| 证券代码：300705 | 证券简称：九典制药 | | | --- | --- | --- | | 债券代码：123223 | 债券简称：九典转02 | 公告编号：2025-075 | 湖南九典制药股份有限公司 关于吸收合并全资子公司的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 一、吸收合并情况概述 为了优化资源配置，提高整体运营效率，湖南九典制药股份有限公司（以下 简称"公司"或"九典制药"）于 2025 年 10 月 23 日召开的第四届董事会第十 三次会议审议通过了《关于吸收合并全资子公司的议案》，拟以公司为主体吸收 合并全资子公司湖南汇阳信息科技有限公司（以下简称"汇阳信息"）。本次吸 收合并完成后，汇阳信息的法人资格将被注销，公司将依法承继其全部资产、债 权债务、合同关系等权利与义务。 本次吸收合并是在原合并报表范围内的合并，本事项不构成关联交易，也不 构成《上市公司重大资产重组管理办法》规定的重大资产重组。本次吸收合并不 涉及公司注册资本等事项的变更。根据《深圳证券交易所创业板股票上市规则》 和《公司章程》的相关规定，本次事项不涉及支 ...

Company Overview - Jiu Tian Pharmaceutical Co., Ltd. is located in Changsha High-tech Development Zone, Hunan Province, and was established on January 19, 2001. The company was listed on October 10, 2017. Its main business involves the research, production, and sales of pharmaceutical products [1] - The revenue composition of the company includes: 82.47% from pharmaceutical preparations, 7.65% from active pharmaceutical ingredients, 6.03% from pharmaceutical excipients, 3.16% from extracts and others, 0.63% from technology transfer and services, and 0.05% from other sources [1] Stock Performance - As of October 23, Jiu Tian Pharmaceutical's stock price decreased by 2.06%, trading at 16.67 CNY per share, with a market capitalization of 8.339 billion CNY. The stock has declined by 5.50% year-to-date and by 2.69% over the last five trading days [1] - The company experienced a net outflow of 8.7643 million CNY in principal funds, with significant selling pressure observed [1] Financial Performance - For the period from January to June 2025, Jiu Tian Pharmaceutical achieved a revenue of 1.512 billion CNY, representing a year-on-year growth of 10.67%. The net profit attributable to shareholders was 291 million CNY, reflecting a year-on-year increase of 2.57% [2] Shareholder Information - As of June 30, 2025, the number of shareholders decreased by 11.65% to 38,800, while the average number of circulating shares per person increased by 14.35% to 9,542 shares [2] - The company has distributed a total of 450 million CNY in dividends since its A-share listing, with 346 million CNY distributed over the past three years [3] - Among the top ten circulating shareholders, Hong Kong Central Clearing Limited holds 7.0605 million shares, a decrease of 10.6772 million shares from the previous period. Southern CSI 1000 ETF increased its holdings by 524,400 shares [3]

Core Viewpoint - Jiutian Pharmaceutical announced that both the company and its subsidiaries have no overdue external guarantees, no litigation related to external guarantees, and no losses incurred from being judged against such guarantees [2] Group 1 - The company confirmed the absence of overdue external guarantees [2] - There are no ongoing litigations related to external guarantees [2] - The company has not incurred any losses from judgments related to guarantees [2]

Core Viewpoint - Hunan Jiutian Pharmaceutical Co., Ltd. is focusing on the transformation towards innovative drug development, with a significant increase in R&D investment and a stable operational performance in Q3 2025, despite challenges in the broader pharmaceutical industry [2][3]. Group 1: Q3 Operational Performance - The overall operational status in Q3 2025 remained stable, with market demand relatively consistent and sales progressing as planned [2]. - The pharmaceutical manufacturing industry saw a revenue of 12,275.2 billion yuan in the first half of 2025, a year-on-year decrease of 1.2%, and a profit total of 1,766.9 billion yuan, down 2.8% year-on-year [2]. - Despite industry pressures, the sales of medicated plaster in the terminal market showed a yearly increase, with sales expected to exceed 7 billion yuan in 2024, a growth of approximately 10%, and over 4 billion yuan in the first half of 2025, a growth of about 15% [2]. Group 2: Focus on Innovative Drug Transformation - The company is fully transitioning to focus on innovative drug R&D, with chemical innovative drugs as the core direction and some involvement in traditional Chinese medicine [3]. - Key therapeutic areas include pain management, focusing on polypeptide and small molecule drugs, and oncology, concentrating on PDC drug development [3]. - The company plans to invest between 250 million to 300 million yuan in R&D for 2025, indicating a strong commitment to its innovative transformation [3]. Group 3: Competitive Advantages and Market Strategies - The external pain relief market is expected to grow due to increasing health demands and an aging population, providing significant development space [4]. - The company aims to enhance product strength and brand influence in the gel plaster sector, optimizing product structure to meet diverse health needs [4]. - Specific product strategies include leveraging the advantages of JIJ02 gel for acne treatment and expanding indications in the polypeptide drug field, focusing on pain and pulmonary fibrosis [4]. - To address the impact of centralized procurement on key products like Loxoprofen Sodium Gel, the company plans to enhance sales through a comprehensive channel coverage system, increase R&D investment for new product launches, and strengthen cost control through an integrated supply chain [4].

| 证券代码：300705 | 证券简称：九典制药 | 公告编号：2025-072 | | --- | --- | --- | | 债券代码：123223 | 债券简称：九典转02 | | 湖南九典制药股份有限公司 关于为全资子公司提供担保的进展公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 二、担保进展情况 近日，九典宏阳因生产经营需要，分别向长沙银行股份有限公司浏阳支行（以 下简称"长沙银行"）、上海浦东发展银行股份有限公司长沙分行（以下简称"浦 发银行"）申请授信。公司与长沙银行签订了《最高额保证合同》，为九典宏阳 提供最高本金余额为人民币 10,000 万元的保证担保；与浦发银行签订了《最高 额保证合同》，为九典宏阳提供最高本金余额为人民币 46,200 万元的保证担保。 以上担保金额在公司已履行审议程序的担保额度以内，无需履行其他审议程 序。本次担保生效后，公司为九典宏阳提供担保的剩余总额度为人民币 23,800 万元整。 三、被担保人情况 公司名称：湖南九典宏阳制药有限公司 统一社会信用代码：91430122344723202P 类型：有限责 ...

Group 1: Company Overview and Market Conditions - The overall business operation of the company in Q3 2025 remains stable, with market demand relatively steady and sales progressing as planned [2] - The pharmaceutical manufacturing industry saw a revenue of CNY 12,275.2 billion in the first half of 2025, a year-on-year decrease of 1.2%, and a total profit of CNY 1,766.9 billion, down 2.8% [2] - Despite the overall industry pressure, the transdermal patch market is showing a positive growth trend, with sales expected to exceed CNY 7 billion in 2024, a year-on-year increase of approximately 10%, and over CNY 4 billion in the first half of 2025, up about 15% [3] Group 2: Strategic Focus and R&D Investment - The company is fully transitioning to focus on innovative drug research and development, with a core emphasis on chemical and traditional Chinese medicine innovations [4] - The estimated R&D expenditure for the year 2025 is projected to be between CNY 250 million and CNY 300 million [5] - The company is committed to enhancing its product strength and brand influence through continuous R&D, aiming to meet diverse health needs and create long-term value for investors [6][7] Group 3: Competitive Landscape and Product Development - The external pain relief market has significant growth potential, driven by increasing health demands and an aging population [6] - The JIJ02 gel shows advantages over existing acne treatments, such as lower risk of resistance and milder side effects, with plans to expand its indications in the peptide drug area [7] - Following the implementation of centralized procurement for the Loxoprofen Sodium Gel Patch, the company will adopt multi-faceted measures to stabilize its business foundation and ensure long-term growth [7]

Core Viewpoint - The company, Jiutian Pharmaceutical (300705), responded to investor inquiries on October 17, indicating that the number of shareholders and the shareholding ratio of the top ten shareholders will be disclosed in regular reports as per regulations [1] Group 1 - The company confirmed that shareholder information is disclosed in periodic reports [1]

Group 1 - The company is focusing on a strategic transformation towards innovative drug development, with a core emphasis on chemical innovative drugs and a layout for traditional Chinese medicine innovative drugs [2] - In the pain management sector, the company is developing peptide and small molecule drugs, while in the oncology sector, it is concentrating on PDC drugs [2] - The company has received clinical trial approval for JIZM01 and JIZM02, and has submitted production applications for the pepper seven pain relief gel patch [2] Group 2 - The company is optimistic about the market prospects for its anti-inflammatory and pain relief patch, primarily targeting the OTC channel, and plans to enhance sales through resource sharing and product matrix expansion [3] - The JIJ02 gel is expected to complete Phase I clinical trials by mid-next year and initiate Phase II trials, with characteristics that make it superior to existing acne treatments [4] - The company plans to expand the indications for peptide drugs and focus on new project introductions, particularly in pain and pulmonary fibrosis areas [4] Group 3 - The company is currently in the bidding phase for the eleventh batch of national drug procurement for its Loxoprofen sodium gel patch, with submission of application materials and public pricing due by October 27 [5] - The company’s e-commerce strategy is centered around the "big health category," utilizing social e-commerce platforms like Xiaohongshu, Douyin, and Kuaishou for targeted marketing [6]

Group 1: Company Strategy and Focus - The company is fully transforming to focus on innovative drug research and development, with a core emphasis on chemical and traditional Chinese medicine innovations [2][3] - Key therapeutic areas include pain management, with a focus on peptide and small molecule drugs, and oncology, specifically PDC drug development [2] - The company employs a dual approach of independent research and project acquisition to enhance its innovation capabilities and accelerate the commercialization of results [3] Group 2: Product Development and Market Outlook - The company has submitted production applications for its traditional Chinese medicine product, Jiao Qi Pain Relief Gel, which is currently under review [2] - The JIJ02 gel is expected to complete Phase I clinical trials in the first half of next year and will initiate Phase II trials thereafter [5] - The company is optimistic about the market potential for its anti-inflammatory pain relief patch, particularly due to the increasing prevalence of chronic pain among the aging population [4] Group 3: Market Strategy and Sales Channels - The sales strategy for the anti-inflammatory pain relief patch primarily targets OTC channels, with plans to enhance sales through resource sharing and product diversification [4] - The company is currently in the bidding phase for the 11th batch of national drug procurement, with submission of application materials and public pricing scheduled for October 27 [6] - The company plans to leverage e-commerce platforms like Xiaohongshu, Douyin, and Kuaishou to reach health-conscious consumers through content marketing and KOL collaborations [9]

Market Overview - The chemical pharmaceutical sector experienced a decline of 0.66% on October 9, with Nanjing New Pharmaceutical leading the drop [1] - The Shanghai Composite Index closed at 3933.97, up 1.32%, while the Shenzhen Component Index closed at 13725.56, up 1.47% [1] Stock Performance - Notable gainers in the chemical pharmaceutical sector included: - Haichen Pharmaceutical (300584) with a closing price of 63.81, up 13.76% and a trading volume of 155,800 shares, totaling 973 million yuan [1] - Changshan Pharmaceutical (300255) closed at 49.29, up 8.21% with a trading volume of 394,400 shares, totaling 1.916 billion yuan [1] - Conversely, Nanjing New Pharmaceutical (688189) saw a significant drop of 19.96%, closing at 9.10 with a trading volume of 32,300 shares, totaling 29.426 million yuan [2] Capital Flow - The chemical pharmaceutical sector experienced a net outflow of 1.108 billion yuan from institutional investors, while retail investors saw a net inflow of 544 million yuan [2] - The capital flow for specific stocks showed: - Changshan Pharmaceutical had a net inflow of 14.6 million yuan from institutional investors, but a net outflow of 14 million yuan from retail investors [3] - Haichen Pharmaceutical recorded a net inflow of 85.3 million yuan from institutional investors, with retail investors showing a net outflow of 68 million yuan [3]