证券代码：301293 证券简称：三博脑科 公告编号：2025-052 三博脑科医院管理集团股份有限公司 关于部分募投项目结项并将节余募集资金永久补充流动资金及注销 募集资金专户的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假 记载、误导性陈述或重大遗漏。 经中国证券监督管理委员会证监许可〔2023〕534 号文《关于同意三博脑科 医院管理集团股份有限公司首次公开发行股票注册的批复》同意注册，并经深圳 证券交易所同意，公司首次公开发行人民币普通股（A 股）39,612,900 股，每股 面值人民币 1.00 元，发行价格为 29.60 元/股。本次发行募集资金总额 117,254.1840 万元；扣除发行费用（不含增值税）后，募集资金净额为 106,163.91 万元，募集 资金已于 2023 年 4 月 27 日划至公司指定账户，立信会计师事务所（特殊普通合 伙）对公司本次公开发行新股的资金到位情况进行了审验，并于 2023 年 4 月 27 日出具了"信会师报字[2023]第 ZB10925 号"《验资报告》。 二、募集资金存放与管理情况 为规范公司募集资金的管理和使用，保护投资 ...

证券代码：301293 证券简称：三博脑科 公告编号：2025-051 一、董事会会议召开情况 三博脑科医院管理集团股份有限公司（以下简称"公司"）第三届董事会第十 六次会议于 2025 年 12 月 31 日在公司会议室以现场结合通讯的方式召开。会议 通知于 2025 年 12 月 26 日以电子邮件等方式发出。本次会议应出席董事 9 名， 实际出席的董事 9 人，会议由董事长张阳先生主持，公司高级管理人员列席了会 议。本次会议的召集、召开和表决程序符合《公司法》等法律法规和《公司章程》 的有关规定。 二、董事会会议审议情况 经与会董事认真审议，会议形成了如下决议： （一）审议通过《关于部分募投项目结项并将节余募集资金永久补充流动资 金及注销募集资金专户的议案》 经审议，董事会同意将"首都医科大学三博脑科医院建设项目"结项，同意注 销募集资金专户，并将截至 2025 年 12 月 22 日的节余募集资金 7,027.72 万元（含 扣除手续费后的利息收入、现金管理收益等，实际金额以资金转出当日募集资金 专户余额为准）永久补充流动资金，用于公司日常生产经营及业务发展。公司本 次将节余募集资金永久补充流动资金， ...

中信证券股份有限公司 关于三博脑科医院管理集团股份有限公司 部分募投项目结项并将节余募集资金永久补充流动资金 及注销募集资金专户 的核查意见 深圳证券交易所： 中信证券股份有限公司（以下简称"中信证券"或"保荐人"）作为三博脑科医 院管理集团股份有限公司（以下简称"三博脑科"或"公司"）首次公开发行股票并 在创业板上市持续督导保荐机构，根据《证券发行上市保荐业务管理办法》《上 市公司监管指引第 2 号——上市公司募集资金管理和使用的监管要求》《深圳证 券交易所创业板股票上市规则》《深圳证券交易所上市公司自律监管指引第 2 号 ——创业板上市公司规范运作》《深圳证券交易所上市公司自律监管指引第 13 号——保荐业务》等有关规定，对公司部分募投项目结项并将节余募集资金永久 补充流动资金及注销募集资金专户的事项进行了核查，具体情况如下： 一、募集资金基本情况 经中国证券监督管理委员会（以下简称"中国证监会"）证监许可〔2023〕 534 号文《关于同意三博脑科医院管理集团股份有限公司首次公开发行股票注册 的批复》同意注册，并经深圳证券交易所同意，公司首次公开发行人民币普通股 （A 股）39,612,900 股，每股 ...

Market Overview - The A-share market experienced mixed performance with the Shanghai Composite Index recording a "9 consecutive days of gains" as of December 29, 2023, marking a slight increase of 0.04% [1] - The Shenzhen Component Index and the ChiNext Index fell by 0.49% and 0.66% respectively, while the North Star 50 Index decreased by 0.45% [1] - Total trading volume in the Shanghai and Shenzhen markets was 21,577 billion yuan, a decrease of 234 billion yuan from the previous day [1] Multi-Financial Sector - The multi-financial sector showed active performance, with stocks like Lakala leading the gains, and companies such as Cuiwei Co., Luxin Venture Capital, and Yuexiu Capital reaching around 10% limit up [3] - On December 26, the Shanghai Stock Exchange announced new guidelines to support high-quality commercial rocket enterprises under the Sci-Tech Innovation Board, which is expected to accelerate the development of the commercial aerospace industry [3] - The rapid growth of the commercial aerospace sector is projected to create significant market opportunities for carbon fiber composite materials, which can account for 70%-90% of the structural weight in spacecraft [3] Carbon Fiber Industry - Shanxi Securities noted that leading companies in the carbon fiber industry are announcing price increases, indicating a recovery in industry conditions [4] - The market for carbon fiber is showing clear differentiation, with general products facing strong competition, while high-end applications in aerospace, hydrogen storage, and wind power require consistent performance and reliable supply [4] - According to Baichuan Yingfu, China's actual consumption of carbon fiber is expected to reach 96,446 tons in 2025, a year-on-year increase of 71.89%, primarily driven by the wind power and aerospace sectors [4] Brain-Computer Interface Sector - The brain-computer interface sector saw significant gains, with Haige Communication reaching around 10% limit up, followed by companies like Meihao Medical and Mcland [5] - On December 26, the National Medical Products Administration released a list of high-end medical devices for priority approval, which includes implantable brain-computer interface devices [5] - The global brain-computer interface market is currently valued at several billion dollars and is expected to exceed 10 billion dollars by 2030, with the medical application market projected to reach 40 billion dollars by 2030 and 145 billion dollars by 2040 according to McKinsey [5][6]

Core Viewpoint - The brain-computer interface (BCI) sector is experiencing significant growth driven by favorable policies, technological advancements, and increased investment interest, as evidenced by the recent surge in stock prices of related companies in both Hong Kong and A-share markets [2][6][7]. Policy Developments - The National Medical Products Administration has included implantable brain-computer interface medical devices in the "Priority Approval List for High-end Medical Devices (2025 Edition)" [2]. - A joint initiative by seven ministries, including the Ministry of Industry and Information Technology, has set phased goals for the BCI industry by 2027 and 2030 [3]. - The "14th Five-Year Plan" emphasizes the BCI sector as a key area for fostering new economic growth [4]. - The National Healthcare Security Administration has introduced new pricing guidelines for invasive BCI procedures, facilitating reimbursement pathways [4]. Technological Advancements - Recent breakthroughs in BCI technology include the first domestically developed fully implanted, wireless BCI product by Brain Tiger Technology, which successfully completed its first clinical trial [5]. - The National Medical Products Administration has approved the world's first invasive BCI product for treating addiction-related mental disorders [5]. - Ongoing clinical trials and collaborations among research institutions and medical units are yielding significant progress in the field [5]. Market Insights - The BCI industry is entering a rapid commercialization phase, supported by policy backing, technological breakthroughs, and increased capital influx [5][6]. - The market for BCI is projected to be a nearly $10 billion opportunity globally, with domestic companies making strides in flexible electrodes and real-time Chinese language decoding [7]. - Investment interest in the BCI sector is rising, particularly in rehabilitation applications and non-invasive BCI technologies, as companies strategically position themselves for future growth [6][7].

Group 1 - The brain-computer interface concept sector rose by 1.62%, ranking 6th among concept sectors, with 34 stocks increasing in value [1][2] - Leading stocks in the sector included Haige Communication, which hit the daily limit, and others like Meihao Medical and Mcland, which rose by 8.30%, 8.22%, and 7.21% respectively [1][2] - The sector experienced a net inflow of 678 million yuan from main funds, with 25 stocks receiving net inflows, and 7 stocks exceeding 50 million yuan in net inflow [2][3] Group 2 - Haige Communication had the highest net inflow of main funds at 724 million yuan, followed by Innovative Medical, Sanbo Brain Science, and Century Huatu, with net inflows of 166 million yuan, 77.5 million yuan, and 76 million yuan respectively [2][3] - The net inflow ratios for Haige Communication, Meihao Medical, and Innovative Medical were 21.95%, 11.38%, and 11.34% respectively, indicating strong investor interest [3][4] - Other notable stocks included Sanbo Brain Science with a 7.21% increase and a net inflow ratio of 6.28% [3][4]

Market Overview - The A-share market experienced fluctuations, with the Shanghai Composite Index closing up 0.04% at 3965.28 points, marking a nine-day rise, while the Shenzhen Component Index fell 0.49% to 13537.1 points, and the ChiNext Index dropped 0.66% to 3222.61 points. The total trading volume in both markets reached 2.14 trillion yuan, with over 3300 stocks declining [1] Hot Sectors - The commercial aerospace sector continued to show strength, with over ten stocks hitting the daily limit, including Shenjian Co. with eight consecutive limit-ups. The recent announcement from the Shanghai Stock Exchange regarding new listing rules for commercial rockets is expected to drive demand in related industries such as satellite manufacturing and ground equipment [2] - The brain-computer interface sector saw significant gains, with stocks like Haige Communication and Xilinmen hitting the daily limit. This surge followed the opening of the Fifth Frontier Brain Science and Industry Conference, which launched the "Guangdong-Hong Kong-Macao Greater Bay Area Brain Science and Central Nervous System Disease AI Innovation Alliance" [3] - The carbon fiber sector experienced a rally, with stocks like Heshun Technology and Jilin Chemical Fiber hitting the daily limit. This was influenced by Toray's announcement of a price increase for its carbon fiber products, expected to improve market conditions [4] - The robotics sector remained active, with stocks such as Awat New Materials and Buke Co. hitting the daily limit and reaching historical highs. The establishment of a humanoid robot standardization committee is anticipated to drive growth in specialized robotics [5] Institutional Insights - CITIC Securities noted that a year-end market rally has begun, driven by optimistic expectations among institutional investors, improved overseas liquidity, and a series of policy announcements. Key sectors to watch include non-ferrous metals and AI computing power, with commercial aerospace remaining the primary focus [6] - Guosheng Securities suggested that the market is likely to confirm its direction before the holiday, despite ongoing adjustments. They highlighted the potential for a mid-term reversal in various sectors [8] - Huatai Securities indicated that while the overseas environment has improved, the A-share market may still experience volatility in the short term due to a lack of cohesive funding and ongoing policy uncertainties. They recommend focusing on sectors with improving fundamentals, such as batteries and certain chemicals [9]

Group 1 - The A-share market's brain-computer interface sector experienced a collective surge, with Xiangyu Medical rising over 9%, Sanbo Brain Science, Meihao Medical, Mylande, and Innovation Medical increasing over 6%, and Xilinmen, Pulite, and Botuo Bio rising over 5% [1] - The Fifth Frontier of Brain Science and Industry Conference and the 2025 Shenzhen Brain-Computer Interface Expo commenced on December 28, marking a significant event in the sector [1] - The "Guangdong-Hong Kong-Macao Greater Bay Area Brain Science and Central Nervous System Disease AI Innovation Alliance" was officially launched, indicating a collaborative effort to advance brain science and technology [1]

Core Viewpoint - Sanbo Brain Science (301293) has made significant improvements in its operations following the relocation of its Kunming branch to a new facility, which includes the addition of a cardiology department and advanced medical equipment [1] Group 1: Facility Improvements - The new Kunming facility has been equipped with a medical linear accelerator, gamma knife, and hyperbaric oxygen chamber, leading to a substantial enhancement in the hospital environment [1] - After operating for a period, the business volume at the new location has shown a noticeable increase compared to the old facility [1] Group 2: New Operations - The Xi'an Sanbo branch, which opened in September this year, is currently in a ramp-up phase and requires time for market cultivation and patient attraction [1] - As a result, the current patient visit volume and bed occupancy rate have not yet reached full capacity [1]

Investment Rating - The industry investment rating for the pharmaceutical and biotechnology sector is "Hold" [2]. Core Insights - The report highlights significant breakthroughs in the domestic brain-computer interface (BCI) technology, indicating an acceleration in industry development and international recognition [5]. - The report emphasizes the transition of invasive brain-computer interfaces from laboratory settings to market approval processes, suggesting a rapid expansion of application scenarios [6]. Summary by Relevant Sections Industry Overview - The report discusses the recent advancements in invasive brain-computer interface technology, including the first domestic medical device entering the FDA's breakthrough therapy pathway, which enhances the international recognition of China's BCI technology [5]. - It mentions successful clinical trials using high-throughput wireless invasive BCI systems, enabling patients with high-level paralysis to control smart wheelchairs and robotic dogs through brain signals, achieving a 15%-20% improvement in brain control performance [5]. Investment Recommendations - The report suggests focusing on companies such as Innovation Medical, Aipeng Medical, and Sanbo Brain Science, as they are positioned to benefit from the advancements in the BCI sector [6].