Eli Lilly has revealed it is to build an active pharmaceutical product (API) facility in Texas, US, a week after revealing Virginia as the first site in its $27bn US manufacturing drive. The $6.5bn manufacturing facility will produce Eli Lilly’s array of small molecule therapeutics – chief among which will be orforglipron, the drugmaker’s oral glucagon-like peptide-1 receptor agonist (GLP-1RA) hopeful in obesity treatment. Lilly’s CEO David Ricks said: "Our new Houston site will enhance Lilly's ability t ...

Eli Lilly and Company has announced plans to invest $6.5bn in an active pharmaceutical ingredients (API) manufacturing facility at Generation Park in Houston, in the US state of Texas. The new facility will produce APIs for small-molecule medicines, including those targeting oncology, cardiometabolic health, immunology and neuroscience. It will create 615 permanent jobs, including positions for scientists, engineers, lab technicians and operations personnel. The construction phase will generate 4,000 jo ...

Core Viewpoint - Eli Lilly's CEO Dave Ricks criticized the UK as "probably the worst country in Europe" for drug prices, highlighting the need for government reforms in the pharmaceutical pricing landscape [1] Company Summary - Eli Lilly is facing challenges in the UK market due to unfavorable drug pricing policies, which may impact its competitive position and profitability in the region [1] Industry Summary - The comments from Eli Lilly's CEO reflect broader concerns within the pharmaceutical industry regarding pricing pressures in Europe, particularly in the UK, which could lead to calls for policy changes to improve market conditions for drug manufacturers [1]

Core Insights - Eli Lilly and Company is recognized as one of the best pharmaceutical stocks, particularly excelling in obesity treatments and expanding its global presence [1] Group 1: Product Development and Market Expansion - The obesity drug franchise, led by Mounjaro (tirzepatide), has rapidly expanded beyond the U.S. to regions including Europe, Asia, the Middle East, Mexico, Brazil, India, and China [2] - New clinical trial data indicates that Orforglipron, an oral GLP-1 agonist, has outperformed Novo Nordisk's Rybelsus in blood sugar control and weight loss for type 2 diabetes patients [3] Group 2: Manufacturing and Investment - Eli Lilly announced a $5 billion facility near Richmond, Virginia, focused on bioconjugates and monoclonal antibodies, as part of a broader $27 billion investment plan for four U.S. plants [4] - This investment is aimed at enhancing capabilities in next-generation oncology and autoimmune therapies [4] Group 3: Regulatory Approvals and Acquisitions - The Alzheimer's drug donanemab (Kisunla) has received an FDA-approved dosing schedule and positive feedback from European regulators [5] - The acquisition of Verve Therapeutics for $1.3 billion is expected to strengthen Eli Lilly's innovation capabilities [5] Group 4: Pricing Strategy and Policy Impact - Eli Lilly introduced a flat-rate $499 monthly pricing model for Zepbound, aimed at improving affordability [6] - Upcoming U.S. policy changes, including Medicaid coverage for GLP-1 weight-loss drugs in 2026 and Medicare in 2027, could further enhance demand [6]

Core Viewpoint - Eli Lilly is expected to report significant earnings growth in the upcoming earnings release, with a projected EPS increase of 444.07% year-over-year and a revenue increase of 40.32% [2]. Company Performance - Eli Lilly's stock closed at $746.98, reflecting a -1.06% change from the previous day, underperforming the S&P 500's loss of 0.55% [1]. - Prior to this trading session, Eli Lilly's shares had gained 8.57%, outperforming the Medical sector's loss of 0.2% and the S&P 500's gain of 3.64% [1]. Earnings Estimates - The upcoming earnings report is anticipated on October 30, 2025, with an expected EPS of $6.42 and quarterly revenue projected at $16.05 billion [2]. - For the annual period, the Zacks Consensus Estimates predict earnings of $23.03 per share and revenue of $61.81 billion, representing increases of +77.29% and +37.22% respectively [3]. Analyst Estimates - Recent modifications to analyst estimates for Eli Lilly indicate a positive outlook, with a 0.21% increase in the Zacks Consensus EPS estimate over the last 30 days [6]. - Eli Lilly currently holds a Zacks Rank of 3 (Hold), reflecting a neutral sentiment among analysts [6]. Valuation Metrics - Eli Lilly is trading at a Forward P/E ratio of 32.78, which is a premium compared to the industry average of 14.65 [7]. - The company has a PEG ratio of 1.06, which is lower than the Large Cap Pharmaceuticals industry's average PEG ratio of 1.53 [7]. Industry Context - The Large Cap Pharmaceuticals industry, part of the Medical sector, holds a Zacks Industry Rank of 63, placing it in the top 26% of over 250 industries [8]. - Strong individual industry groups, as measured by the Zacks Industry Rank, tend to outperform weaker groups by a factor of 2 to 1 [8].

礼来此举也是对美国总统特朗普最新关税政策威胁的积极回应。特朗普此前表示，可能对进口到美国的 药品征收关税，以推动制药企业将生产环节重新迁回美国。过去十年，美国本土药品制造业规模显著萎 缩。 分析人士认为，礼来扩大在美国的产能布局，不仅是为了满足市场需求，也是为了降低政策不确定性带 来的供应链风险。 根据公司公告，休斯敦新工厂将主要生产orforglipron以及其他针对心脏代谢健康、肿瘤学、免疫学和神 经科学等领域的小分子药物。小分子药物通常以口服片剂形式出现，不仅对患者使用更方便，也更易于 大规模生产，制造成本相对更低。 礼来表示，该项目将为大休斯敦地区带来615个全职岗位，包括工程师、科学家、运营人员和实验室技 术人员，同时在建设过程中创造4000个建筑相关工作岗位。 制药巨头礼来(LLY.US)周二宣布，将投资65亿美元在美国德克萨斯州休斯敦建设一座全新生产设施，以 扩大其小分子药物产能，重点用于生产备受市场关注的实验性口服减肥药orforglipron。 这将是礼来今年宣布的第二项重大投资计划。早在今年2月，礼来已宣布计划斥资至少270亿美元在美国 新建四家制造工厂，此前自2020年以来，公司在美国国 ...

Key TakeawaysFord (F) has expanded a recall to 4,632 Expedition and Navigator SUVs from the 2020 model year due to a battery junction box circuit board short risk, with two underhood fires reported, though no stop-driving instructions have been issued.Disney+ (DIS) is set to implement another price hike in October, with the ad-supported plan increasing by $2 to $11.99 and the premium no-ads plan rising by $3, reflecting ongoing "streamflation" in the digital entertainment sector.Federal Reserve Chair Jerome ...

The planned site, which will be used to manufacture the company's first oral weight-loss drug, is expected to be operational within five years. ...

Core Insights - Eli Lilly is set to produce its next-generation experimental weight-loss pill, orforglipron, at a new multi-billion-dollar manufacturing facility in Texas [1] Company Developments - The new manufacturing plant will be dedicated to the production of orforglipron, indicating a significant investment in expanding the company's capabilities in the weight-loss medication market [1]

Eli Lilly on Tuesday said it will spend $6.5 billion to build a manufacturing facility in Houston, Texas, to boost production of the company's pipeline of so-called small molecule drugs, including its closely watched experimental obesity pill. It is the second in a string of new planned U.S. investments by the drugmaker. Eli Lilly announced in February that it would spend at least $27 billion to build four new domestic manufacturing plants, adding to $23 billion in previous investments since 2020. Eli Lilly ...