板块表现： 证券研究报告 医药生物 行业定期报告 hyzqdatemark 2026 年 02 月 09 日 刘闯 SAC：S1350524030002 liuchuang@huayuanstock.com 分子胶：撬动"不可成药"靶点的创新药新范式 投资评级： 看好（维持） ——医药行业周报（26/2/2-26/2/6） 投资要点： 请务必仔细阅读正文之后的评级说明和重要声明 证券分析师 联系人 本周医药市场表现分析：2 月 2 日至 2 月 6 日，医药指数上涨 0.14%，相对沪深 300 指数超 额收益为 1.47%。上周市场风格有所变化，白酒等底部消费类资产表现较好，医药行业中的 医疗服务、中药亦有表现。另外，经历短期波动消化后，创新药板块已显现企稳回暖迹象。 我们建议精选基本面强劲、前期调整充分的创新药个股，看好未来股价有望走出新高度，同 时建议积极关注医疗新科技等板块，以及 26 年困境反转的底部个股。1）创新药建议关注，A 股）恒瑞医药、信立泰、泽璟制药、热景生物、科伦药业、上海谊众、康弘药业、华纳药厂、 前沿生物、福元医药、苑东生物、昂利康；港股）中国生物制药、三生制药、信达生物、康 方生物 ...

Investment Rating - The report maintains an "Accumulate" rating for the pharmaceutical and biotechnology industry [1] Core Insights - The pharmaceutical index in A-shares has shown a slight increase of 0.14% this week and 3.28% year-to-date, outperforming the CSI 300 by 1.41% and 0.85% respectively [3][8] - The report highlights the emergence of molecular glue as a significant trend in the industry, with several successful stocks like RVMD, GLU, and KYMR, and substantial business development (BD) activities [3][15] - The report suggests that molecular glue has the potential to create new blockbuster drugs in oncology and autoimmune diseases, urging investors to focus on domestic companies involved in this area [3][11] Summary by Sections 1. Market Performance - The A-share pharmaceutical index has outperformed the CSI 300 index, with notable gains in traditional Chinese medicine (2.56%), medical services (1.31%), and raw materials (0.64%) [3][8] - The report lists top-performing stocks, including Guangsheng Tang (+29.83%) and HaiXiang Pharmaceutical (+18.64%), while noting declines in stocks like Changshan Pharmaceutical (-15.78%) [8] 2. Molecular Glue - Molecular glue is defined as a class of small molecule drugs that facilitate the binding of E3 ubiquitin ligases to previously unrecognized pathogenic target proteins, leading to their degradation [15] - The report mentions that BMS has two marketed molecular glues with peak sales exceeding $16 billion, and ongoing research into new iterations [3][15] - Domestic companies such as Yuan Dong Biology and Jin Fang Pharmaceutical are noted for their potential in molecular glue development [3][11] 3. R&D Progress and Corporate Developments - The report highlights significant clinical research milestones, including Pfizer's initiation of a Phase II/III trial for its PD-1/VEGF bispecific antibody SSGJ-707 [3] - It also notes that Novartis has submitted its BAFF-R monoclonal antibody for approval in China, and AbbVie has started a Phase II trial for its Bcl-2 inhibitor Venetoclax [3] 4. Recommended Stocks - The report provides a list of recommended stocks across various sectors, including: - CXO and upstream research services: WuXi AppTec, Hao Yuan Pharmaceutical, and Aopumai [11] - Traditional Chinese medicine: Zuo Li Pharmaceutical and Fang Sheng Pharmaceutical [11] - PD-1 PLUS: 3SBio, KANGFANG Biologics, and Innovent Biologics [11] - ADC: Ying En Biologics and Kelong Biotechnology [11] - AI drug development: Jing Tai Holdings [11]

证券研究报告·行业跟踪周报·医药生物 医药生物行业跟踪周报 分子胶海外风起，国内管线蓄势破局 2026 年 02 月 09 日 增持（维持） [Table_Tag] [Table_Summary] 投资要点 证券分析师 朱国广 执业证书：S0600520070004 zhugg@dwzq.com.cn 行业走势 -8% -4% 0% 4% 8% 12% 16% 20% 24% 2025/2/10 2025/6/10 2025/10/8 2026/2/5 医药生物 沪深300 相关研究 《降息等多因素支持科研上游持续复 苏，重点推荐皓元医药、奥浦迈等》 2026-02-01 《mRNA 疫苗龙头释放积极临床数据 信号，建议关注悦康药业、康希诺等》 2026-01-26 东吴证券研究所 1 / 45 请务必阅读正文之后的免责声明部分 ◼ 本周、年初至今 A 股医药指数涨幅分别为 0.14%、3.28%，相对沪深 300 的超额收益分别为 1.41%、0.85%；本周、年初至今恒生生物科技指数涨 跌幅分别为-1.31%、7.34%，相对于恒生科技指数跑赢 5.20%、10.41%； 本周中药（2.56%）、医疗服务 ...

证券研究报告 行业周报 礼来替尔泊肽全线爆发，2025年合计贡献365亿美元 生物医药行业强于大市（维持） 平安证券研究所生物医药团队 分析师： 叶寅投资咨询资格编号:S1060514100001邮箱：YEYIN757@PINGAN.COM.CN 倪亦道投资咨询资格编号:S1060518070001邮箱：NIYIDAO242@PINGAN.COM.CN 韩盟盟投资咨询资格编号:S1060519060002邮箱：HANMENGMENG005@PINGAN.COM.CN 裴晓鹏投资咨询资格编号:S1060523090002邮箱：PEIXIAOPENG719@PINGAN.COM.CN 何敏秀投资咨询资格编号:S1060524030001邮箱：HEMINXIU894@PINGAN.COM.CN 王钰畅投资咨询资格编号:S1060524090001邮箱：WANGYUCHANG804@PINGAN.COM.CN 曹艳凯投资咨询资格编号:S1060524120001邮箱：CAOYANKAI947@PINGAN.COM.CN 张梦鸽投资咨询资格编号:S1060525070003邮箱：ZHANGMENGGE752@PINGA ...

Group 1: Company Overview - Chengdu Sailano Medical Technology Co., Ltd. (Sailano) has officially signed to establish its headquarters in Chengdu Tianfu International Bio-City, focusing on the field of structural heart disease [1][3] - Sailano aims to become a unicorn in the field of pan-cardiac disease medical devices, with a global innovation capability and a forward-looking vision [3] - The company holds 21 invention patents and 19 utility model patents, showcasing its strong intellectual property portfolio [3] Group 2: Research and Development - Sailano plans to build a headquarters, R&D center, and production base in the bio-city to systematically conduct research, production, and sales of medical devices for structural heart disease [3] - The company has established close clinical trial cooperation with top cardiac centers in China, creating a collaborative innovation system from clinical needs to technology transfer [3] - Sailano's product pipeline targets the core area of interventional treatment for structural heart disease, with several in-development products possessing "international advanced" technical advantages [3] Group 3: Clinical Applications and Collaborations - The company will leverage its existing clinical cooperation network and R&D platform to accelerate clinical research, registration, and industrialization of core products after settling in the bio-city [3] - The high-frequency skin ultrasound technology developed by Tianfu Jin Cheng Laboratory has entered clinical validation, providing a new tool for skin disease diagnosis and treatment evaluation [6][10] - The technology aims to enhance the precision of skin disease diagnosis by offering non-invasive, real-time imaging capabilities [10] Group 4: Industry Developments - Chengdu Biomedicine has seen multiple advancements in various subfields, including the structural heart disease sector [4] - Chengdu Baili Tianheng Pharmaceutical Co., Ltd. has been recognized in the "2025 Hurun China 500" list, ranking 86th with a value of 153 billion yuan, an increase of 79.5 billion yuan [12] - Baili Tianheng is developing innovative drugs in the tumor macromolecule treatment field and has received multiple breakthrough therapy designations from regulatory agencies [12]

2月6日，苑东生物跌5.02%，截至发稿，报66.20元/股，成交2.12亿元，换手率1.78%，总市值116.86亿 元。 资料显示，成都苑东生物制药股份有限公司位于四川省成都市双流区安康路8号，成立日期2009年6月1 日，上市日期2020年9月2日，公司主营业务涉及化学原料药和化学药制剂的研发、生产与销售。主营业 务收入构成为：制剂销售78.75%，原料药销售9.22%，技术服务及转让6.79%，CMO/CDMO4.01%，其 他1.22%。 从基金十大重仓股角度 声明：市场有风险，投资需谨慎。 本文基于第三方数据库自动发布，不代表新浪财经观点，任何在本 文出现的信息均只作为参考，不构成个人投资建议。如有出入请以实际公告为准。如有疑问，请联系 biz@staff.sina.com.cn。 数据显示，申万菱信基金旗下1只基金重仓苑东生物。申万菱信医药先锋股票A（005433）四季度增持 5.99万股，持有股数18.15万股，占基金净值比例为5.01%，位居第七大重仓股。根据测算，今日浮亏损 失约63.51万元。 责任编辑：小浪快报 申万菱信医药先锋股票A（005433）成立日期2020年11月16日，最新 ...

Market Performance - The chemical pharmaceutical sector increased by 1.41% on February 3, with Yiming Pharmaceutical leading the gains [1] - The Shanghai Composite Index closed at 4067.74, up 1.29%, while the Shenzhen Component Index closed at 14127.1, up 2.19% [1] Top Gainers in Chemical Pharmaceutical Sector - Yiming Pharmaceutical (002826) closed at 20.98, up 9.27% with a trading volume of 269,200 shares and a transaction value of 559 million [1] - Yuandong Biological (688513) closed at 68.90, up 8.85% with a trading volume of 64,600 shares [1] - Nami Technology (688690) closed at 29.00, up 7.01% with a trading volume of 93,900 shares and a transaction value of 265 million [1] - Lianhuan Pharmaceutical (600513) closed at 20.15, up 5.94% with a trading volume of 162,200 shares and a transaction value of 323 million [1] Top Losers in Chemical Pharmaceutical Sector - Shuangbi Pharmaceutical (002038) closed at 6.41, down 7.10% with a trading volume of 801,300 shares and a transaction value of 511 million [2] - Haizhi Pharmaceutical (002653) closed at 47.50, down 5.47% with a trading volume of 90,200 shares and a transaction value of 430 million [2] - Nuo Cheng Jianhua (688428) closed at 21.13, down 3.78% with a trading volume of 163,500 shares [2] Capital Flow Analysis - The chemical pharmaceutical sector experienced a net outflow of 42.01 million from institutional investors, while retail investors saw a net inflow of 651 million [2] - The main capital inflow was observed in Yiming Pharmaceutical with 58.98 million, while it faced a net outflow of 58.77 million from retail investors [3] - Other notable inflows included Guangsheng Tang (300436) with 14.8 million from main capital, while it faced a net outflow of 95.56 million from retail investors [3]

Core Viewpoint - China Medical announced that its wholly-owned subsidiary, Tianfang Pharmaceutical Co., Ltd., received approval from the National Medical Products Administration for two drug registration certificates for Dabigatran Etexilate Capsules, a direct thrombin inhibitor used for various thromboembolic conditions [1] Group 1: Product Information - Dabigatran Etexilate is primarily used to reduce the risk of stroke and systemic embolism in patients with non-valvular atrial fibrillation, treat deep vein thrombosis (DVT) and pulmonary embolism (PE), and prevent DVT and PE recurrence [1] - The drug was developed by Boehringer Ingelheim and was launched in Germany and the UK in March 2008, received FDA approval in October 2010, and was launched in China in February 2013 [1] Group 2: Market Context - As of the announcement date, besides Tianfang Pharmaceutical, 13 other companies, including Chengdu Baitai Pharmaceutical Co., Ltd., Jiangsu Hengrui Medicine Co., Ltd., and Chengdu Yuandong Biopharmaceutical Co., Ltd., have obtained production licenses for this drug in China [1] - According to a third-party database, the sales revenue of this drug in China's three major terminal markets is projected to be approximately 571 million yuan in 2024, with an estimated 375 million yuan in the first three quarters of 2025 [1]

Core Viewpoint - Yuan Dong Biotech (688513) has announced the initiation of Phase I clinical trials for its innovative chemical drug EP-0226, aimed at treating neuropathic pain, in collaboration with the Shanghai Institute of Materia Medica and the Zhongke Zhongshan Drug Innovation Research Institute [1] Group 1 - The first subject has been dosed in the clinical trial for EP-0226 [1] - Preclinical studies indicate that EP-0226 demonstrates superior target selectivity, in vivo analgesic activity, and efficacy compared to the approved drug pregabalin [1] - The safety profile of EP-0226 is reported to be good, suggesting it may provide a safe and effective treatment option for patients suffering from neuropathic pain [1]

Core Viewpoint - Yuan Dong Biotech (688513.SH) has initiated Phase I clinical trials for its innovative drug EP-0226, developed in collaboration with the Shanghai Institute of Materia Medica and Zhongke Zhongshan Drug Innovation Research Institute, aimed at treating neuropathic pain [1] Group 1: Drug Development - EP-0226 is a novel calcium channel (Cav2.2) modulator designed to treat neuropathic pain by binding to the calcium channel α2δ subunit, reducing calcium influx in neurons, and consequently decreasing the release of excitatory neurotransmitters such as glutamate and norepinephrine [1] - Preclinical studies indicate that EP-0226 demonstrates superior target selectivity, analgesic activity, and efficacy compared to the approved drug pregabalin, with good safety profiles, potentially offering a new safe and effective treatment option for patients with neuropathic pain [1]