健康元药业集团 关于荷兰子公司获得生产许可证的公告 公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 近日，健康元药业集团股份有限公司（以下简称：本公司）全资子公司 JOINCARE PHARMA NETHERLANDS B.V. 收到荷兰卫生、福利与体育部 （Ministerie van Volksgezondheid, Welzijn en Sport）核准签发的《生产许可证》。 现将有关详情公告如下： 一、生产许可的相关情况 企业名称：JOINCARE PHARMA NETHERLANDS B.V. 许可证编号：109585 F 住所地址：Flight Forum 128A 5657 DD, EINDHOVEN 许可范围：药品进口 证券代码：600380 证券简称：健康元 公告编号：临 2025-046 健康元药业集团股份有限公司 关于荷兰子公司获得生产许可证的公告 发证机关：荷兰卫生、福利与体育部（Ministerie van Volksgezondheid, Welzijn en Sport） 有效日期：自 2025 年 ...

●股东大会召开日期：2025年6月6日 ●本次股东大会采用的网络投票系统：上海证券交易所股东大会网络投票系统 ●公司拟使用上证所信息网络有限公司（以下简称"上证信息"）提供的股东大会提醒服务，委托上证信 息通过智能短信等形式，根据股权登记日的股东名册主动提醒股东参会投票，向每一位投资者主动推送 股东会参会邀请、议案情况等信息。 一、召开会议的基本情况 证券代码：600380 证券简称：健康元 公告编号：临2025-045 健康元药业集团股份有限公司 关于召开2024年年度股东大会的提示性公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容 的真实性、准确性和完整性承担法律责任。 重要内容提示： 4、现场会议召开的日期、时间和地点 召开的日期时间：2025年6月6日14点00分 召开地点：深圳市南山区高新区北区朗山路17号健康元药业集团大厦二号会议室。 5、网络投票的系统、起止日期和投票时间。 网络投票系统：上海证券交易所股东大会网络投票系统 1、股东大会类型和届次 2024年年度股东大会 2、股东大会召集人：董事会 3、投票方式：本次股东大会所采用的表决方式是现场投 ...

健康元药业集团 关于召开 2024 年年度股东大会的提示性公告 证券代码：600380 证券简称：健康元 公告编号：临 2025-045 健康元药业集团股份有限公司 关于召开2024年年度股东大会的提示性公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： ●股东大会召开日期：2025 年 6 月 6 日 ●本次股东大会采用的网络投票系统：上海证券交易所股东大会网络投票系统 ●公司拟使用上证所信息网络有限公司（以下简称"上证信息"）提供的股东大会 提醒服务，委托上证信息通过智能短信等形式，根据股权登记日的股东名册主动提醒股 东参会投票，向每一位投资者主动推送股东会参会邀请、议案情况等信息。 一、召开会议的基本情况 1、股东大会类型和届次 2024 年年度股东大会 2、股东大会召集人：董事会 3、投票方式：本次股东大会所采用的表决方式是现场投票和网络投票相结合的 方式 4、现场会议召开的日期、时间和地点 召开的日期时间：2025 年 6 月 6 日14 点 00 分 召开地点：深圳市南山区高新区北区朗山路 17 ...

Group 1 - The core viewpoint of the articles highlights the rapid development of China's innovative drug industry, supported by government policies, leading to a significant increase in the number of approved innovative drugs [1][2] - Guangdong Zhongsheng Pharmaceutical Co., Ltd. announced the approval of its innovative drug, Anladiwei Tablets, marking a major breakthrough in respiratory system treatment and enhancing the company's market competitiveness [2][3] - The approval of Anladiwei Tablets is expected to contribute positively to the company's future performance, as it expands the product line and strengthens its leading position in the respiratory drug market [2][3] Group 2 - Health元药业集团 announced the approval of its long-acting injectable Aripiprazole Microspheres, which is the first of its kind globally, targeting adult schizophrenia [3] - Sichuan Kelun Pharmaceutical Co., Ltd. made progress in international collaboration by entering into an exclusive licensing agreement for the development of SKB378/HBM9378/WIN378, indicating a strategic move in the innovative drug sector [3] - The overall demand for innovative drugs is expected to grow due to aging populations, changing disease patterns, and increased health awareness, suggesting a significant market opportunity for domestic companies [3]

Group 1 - A total of 25 A-share listed companies disclosed merger and acquisition announcements during the week of May 19 to May 25 [1] - Haiguang Information and Zhongke Shuguang announced plans for a stock swap merger, with Haiguang Information issuing A-shares to all A-share shareholders of Zhongke Shuguang [1] - Both companies' A-shares will be suspended from trading starting May 26, with the suspension expected to last no more than 10 trading days [1] Group 2 - Northern Long Dragon plans to acquire Henan Zhongsheng's equity and related financing, leading to stock suspension [2] - Dike Co., Ltd. intends to acquire 60% of Zhejiang Sute for 696 million yuan, gaining control of the Solamet® photovoltaic silver paste business [2] - China Shenhua plans to acquire 7.43% of the National Energy Group Financial Company for 2.929 billion yuan [2] Group 3 - Yunnan Copper intends to purchase 40% of Liangshan Mining's shares, with stock resuming trading on May 26 [2] - Riyi Electronics plans to acquire 20% of its subsidiary Changzhou Huichang Sensor Co., Ltd. [2] - Hongming Co., Ltd. intends to acquire 83% of Shenzhen Chisu for 151 million yuan, which is expected to constitute a major asset restructuring [2]

Core Insights - Shenzhen has established its first pharmaceutical and medical device industry overseas joint venture to enhance global market access and accelerate the internationalization of local enterprises [1][2] Group 1: Industry Overview - Shenzhen's pharmaceutical and medical device exports are projected to lead major cities in China in 2024, accounting for 12.9% of the national total [1] - The total export value of medical devices from Shenzhen reached 29.8 billion yuan, with a year-on-year growth of 12.3%, representing 21.3% of the national export share [1] - Pharmaceutical exports from Shenzhen totaled 11.5 billion yuan, with a continuous increase in national share, reaching 6.4% in 2024 [1] Group 2: Joint Venture Structure - The joint venture is initiated by leading companies such as Kexing Pharmaceutical and Mindray Medical, along with other prominent firms like Health元 and Haipru [2] - It includes collaboration with professional service institutions in insurance, consulting, legal, and logistics sectors to create a comprehensive support ecosystem for overseas expansion [2] - The joint venture will establish specialized committees for pharmaceutical and medical device exports, facilitating access to international resources and market entry [2] Group 3: Future Initiatives - The joint venture plans to conduct a series of activities including brand promotion, training, and participation in international exhibitions to showcase Shenzhen's pharmaceutical and medical device innovations [2] - It aims to organize training on legal regulations, product registration, and market analysis, enhancing the capabilities of local enterprises for international operations [2] - The initiative will focus on collective participation in international exhibitions across regions such as Europe, South America, and Central Asia to enhance the global visibility of Shenzhen's pharmaceutical and medical device industry [2]

Industry News - Ionis announced positive topline results for its antisense oligonucleotide therapy Tryngolza (Olezarsen) in the Phase 3 Essence clinical trial, significantly reducing triglyceride levels in patients after 6 months and achieving all key secondary endpoints with statistical significance [2] Company News - Health元 announced that its subsidiary LIAN SGP plans to acquire 64.81% of Vietnamese listed company Imexpharm for approximately 15.87 million RMB, which is a leading pharmaceutical company in Vietnam with products that include antibiotics and cardiovascular drugs, showing high synergy with Health元's existing products [3] - 众生药业 reported that its subsidiary 众生睿创's innovative drug Angladiwe tablets received approval from the National Medical Products Administration, being the first global RNA polymerase PB2 protein inhibitor for treating adult patients with uncomplicated influenza A [3] - 科伦药业 announced that its subsidiary 科伦博泰's new indication application for the ADC drug sac-TMT has been accepted by CDE, aimed at treating adults with HR+ and HER2- breast cancer who have previously received endocrine therapy and other systemic treatments [3] - 艾力斯 announced that its KRASG12C inhibitor, citric acid gorasetinib tablets, has received approval from the National Medical Products Administration for treating adult patients with advanced non-small cell lung cancer with KRASG12C mutations who have received at least one systemic treatment [4]

Group 1: Stock Performance - Yibin Paper (600793.SH) has experienced a significant short-term stock price increase and a substantial rise in trading volume [1] - Sanofi Health (688336.SH) has seen a cumulative stock price increase of over 100% since May 19, 2025, indicating potential irrational speculation and a possible correction [1] - Laisun Tongling (603900.SH) has shown a notable short-term increase in stock price and turnover rate, exceeding most companies in the industry [1] Group 2: Project Investments - Youyan Powder Materials (688456.SH) plans to establish a subsidiary to invest in an additive manufacturing metal powder materials industrial base [1] - Suqian Agricultural Development (601952.SH) intends to initiate a project for the construction of a 14,000-ton grain storage facility [1] Group 3: Contract Awards - Zhongnan Media (601098.SH) has signed a procurement contract through its wholly-owned subsidiary [1] Group 4: Operating Data - China Power Construction (601669.SH) reported a total new contract amount of 386.49 billion yuan from January to April, a year-on-year decrease of 4.9% [1] - China Chemical (601117.SH) recorded a total contract amount of 123.017 billion yuan from January to April [1] Group 5: Equity Acquisitions - Health元 (600380.SH) announced that its controlling subsidiary, Lizhu Group, plans to acquire equity in Vietnam's IMP company [1] Group 6: Share Buybacks - Geling Deep Vision (688207.SH) has completed a buyback of 1.29% of its shares [1] Group 7: Shareholding Changes - Yiwan Yichuang (300792.SZ) shareholders Zhang Fan and director Lu Hualiang plan to reduce their holdings by up to 3.02% [1] - Daqian Ecology (603955.SH) has announced that Xinhua Publishing Group intends to reduce its holdings by up to 3% [1] - Hongli Zhihui (300219.SZ) controlling shareholder plans to increase holdings by 25 million to 50 million yuan [1] - Sanfeng Environment (601827.SH) controlling shareholder intends to increase holdings by 150 million to 300 million yuan [1] - Chengdu Xian Dao (688222.SH) plans to increase holdings by 25 million to 50 million yuan [1] Group 8: Strategic Partnerships - Tiantie Technology (300587.SZ) has signed a strategic cooperation framework agreement with Xinjie Energy [2]

Group 1 - Health元 announced that its subsidiary, Lijuz Group, plans to acquire 64.81% of Imexpharm Corporation for approximately 5.73 trillion VND (about 1.587 billion RMB), which represents 11.45% of Lijuz Group's latest audited net assets [1] - Imexpharm Corporation is a Vietnamese pharmaceutical company engaged in the research, production, and sales of drugs, including antibiotics and cardiovascular medications [1] - After the acquisition, Imexpharm will become a subsidiary of Lijuz Group, aiding in the expansion of the group's overseas market [1] Group 2 - Lijuz Group's revenue has been under pressure, with a reported revenue of 11.812 billion RMB in 2024, a decrease of 4.97% year-on-year, while net profit increased by 5.50% to 2.061 billion RMB [2] - The decline in revenue is attributed to price reductions from national medical insurance negotiations affecting key products, as well as decreased sales in antiviral products following reduced demand due to COVID-19 and flu [2] - Health元 also reported a revenue of 15.619 billion RMB in 2024, down 6.17% year-on-year, with a net profit of 1.387 billion RMB, a decrease of 3.90% [2] Group 3 - Lijuz Group is accelerating its international expansion to enhance its risk resilience, with products already covering Southeast Asia, South America, the Middle East, and Africa [3] - The company has initiated the construction of an active pharmaceutical ingredient factory in Indonesia to support local and international production, aiming to reduce costs and improve market responsiveness [3] - In 2024, Lijuz Group achieved overseas revenue of 1.724 billion RMB, a year-on-year increase of 9.69%, accounting for 14.59% of total revenue, which is a 2 percentage point increase from 2023 [3]

Group 1 - The rise of health-conscious food products developed by hospitals reflects a growing consumer desire for healthier eating options, as seen with popular items like medicinal bread and low-sugar mooncakes [1] - The trend indicates a shift in consumer preferences from merely satisfying hunger to prioritizing both taste and health, with products incorporating traditional Chinese medicine ingredients [1] - The increasing prevalence of chronic diseases among younger populations highlights the importance of healthier dietary choices, prompting consumers to seek out nutritious food alternatives [1] Group 2 - The "Chinese medicine + food" innovation path is supported by government initiatives aimed at enhancing the quality of traditional medicine and promoting its integration with the food industry [2] - Jiangsu province is well-positioned to leverage its rich heritage in traditional medicine and advanced food processing capabilities to create a robust market for health-oriented food products [2] - There is a need for professional oversight in the development of "Chinese medicine + food" products to prevent misleading claims and ensure safety and scientific validity in food production [2]