南京诺唯赞生物科技股份有限公司 2025 年第一次临时股东会 会议资料 2025 年 11 月 南京诺唯赞生物科技股份有限公司 2025 年第一次临时股东会会议资料 南京诺唯赞生物科技股份有限公司 2025 年第一次临时股东会会议须知 为维护全体股东合法权益，确保股东会的正常秩序和议事效率，保证股东会 的顺利进行，根据《中华人民共和国公司法》《中华人民共和国证券法》、中国 证券监督管理委员会《上市公司股东会规则》以及《南京诺唯赞生物科技股份有 限公司章程》《南京诺唯赞生物科技股份有限公司股东大会议事规则》等有关规 定，南京诺唯赞生物科技股份有限公司（以下简称"公司"）特制定本次股东会 会议须知： 一、董事会在股东会召开过程中，应当以维护股东的合法权益、确保正常程 序和议事效率为原则，认真履行法定职责。股东会设立秘书处，负责会议有关程 序方面事宜。 二、各股东（含股东代理人，下同）请按照本次股东会会议通知中规定的时 间 和 登 记 方 法 办 理 参 会 手 续 ， 详 见 公 司 刊 登 于 上 海 证 券 交 易 所 网 站 （www.sse.com.cn）的《关于召开 2025 年第一次临时股东会的通知》 ...

Investment Rating - Maintain "Outperform" rating with a target price of 74.78 RMB, reflecting a 10% upside from the current price [4][11]. Core Insights - The innovative drug industry is rebounding, leading to strong company performance with a revenue increase of 32.26% year-on-year in the first three quarters of 2025, reaching 613 million RMB, and a net profit attributable to shareholders of 132 million RMB, up 58.61% [4][11]. - The company has seen rapid quarterly revenue growth, with Q3 2025 revenue at 226 million RMB, representing a year-on-year increase of 37.50% and a quarter-on-quarter increase of 12.32% [12]. - Increased R&D investment has diversified the product range, with nearly 60 GMP-grade products developed for CGT drug CMC, commercialization, and clinical research [13]. Financial Summary - Total revenue projections for 2023A to 2027E are as follows: 544 million RMB (2023A), 645 million RMB (2024A), 840 million RMB (2025E), 1,074 million RMB (2026E), and 1,366 million RMB (2027E), with growth rates of 14.6%, 18.6%, 30.2%, 27.8%, and 27.2% respectively [3]. - Net profit attributable to shareholders is projected to grow from 154 million RMB in 2023A to 354 million RMB in 2027E, with a significant increase of 53.9% in 2025E [3]. - The company’s EPS is forecasted to be 0.92 RMB (2023A), 0.74 RMB (2024A), 1.14 RMB (2025E), 1.53 RMB (2026E), and 2.11 RMB (2027E) [3][4]. R&D and Product Development - The company has developed a series of recombinant proteins and antibodies for CAR-T product development, enhancing its capabilities in the CGT field [12][13]. - In the ADC field, the company offers a range of high-quality products, including target proteins and enzymes for linker cleavage, which are essential for ADC PK research [13].

Market Overview - The Shanghai Composite Index closed at 4018.60 points, above the annual line, with a change of 0.53% [1] - The total trading volume of A-shares reached 2,194.371 billion yuan [1] Stocks Breaking Annual Line - A total of 112 A-shares have surpassed the annual line today, with notable stocks showing significant deviation rates [1] - The stocks with the highest deviation rates include: - Shede Liquor: 9.90% - Binhai Energy: 8.36% - Pinwo Food: 6.38% [1] Detailed Stock Performance - The following table summarizes the performance of stocks that broke the annual line: - Shede Liquor (600702): Today's change of 10.01%, turnover rate of 7.58%, latest price 65.63 yuan [1] - Binhai Energy (000695): Today's change of 9.96%, turnover rate of 5.02%, latest price 12.47 yuan [1] - Pinwo Food (300892): Today's change of 8.84%, turnover rate of 16.98%, latest price 36.70 yuan [1] - Other notable stocks include: - Haida Co. (300320): 8.77% change, 9.19% turnover, latest price 10.91 yuan [1] - Huachao City A (000069): 9.92% change, 3.74% turnover, latest price 2.66 yuan [1] Additional Stocks with Minor Deviations - Stocks with smaller deviation rates that just crossed the annual line include: - Wanxin Media: Minor deviation rate [1] - Chengdu Bank: Minor deviation rate [1] - China Publishing: Minor deviation rate [1]

Market Overview - As of 10:30 AM today, the Shanghai Composite Index is at 3998.79 points, with a slight increase of 0.03% and total A-share trading volume reaching 1,083.642 billion yuan [1] Stocks Breaking Through Annual Line - A total of 76 A-shares have surpassed their annual line today, with notable stocks showing significant deviation rates including Binhai Energy at 8.36%, Overseas Chinese Town A at 6.04%, and Peking University Pharmaceutical at 5.58% [1] - The stocks with the largest deviation rates are as follows: - Binhai Energy: 9.96% increase, turnover rate of 4.54%, annual line at 11.51 yuan, latest price at 12.47 yuan [1] - Overseas Chinese Town A: 9.92% increase, turnover rate of 3.53%, annual line at 2.51 yuan, latest price at 2.66 yuan [1] - Peking University Pharmaceutical: 10.02% increase, turnover rate of 6.51%, annual line at 6.14 yuan, latest price at 6.48 yuan [1] Additional Stocks with Minor Deviations - Other stocks that have just crossed the annual line with smaller deviation rates include: - Shifeng Culture: 7.28% increase, turnover rate of 9.18%, annual line at 20.09 yuan, latest price at 20.92 yuan [1] - Shede Liquor: 3.72% increase, turnover rate of 2.05%, annual line at 59.70 yuan, latest price at 61.88 yuan [1] - Times Energy: 3.05% increase, turnover rate of 1.39%, annual line at 16.45 yuan, latest price at 16.92 yuan [1]

Investment Rating - The report maintains a "Market Weight" rating for the pharmaceutical and biotechnology industry, indicating that the industry is expected to perform within ±10% of the market index over the next six months [3][29]. Core Insights - The SW pharmaceutical and biotechnology industry underperformed the CSI 300 index, declining by 0.61% from October 24 to November 6, 2025, which is approximately 2.50 percentage points lower than the index [10][23]. - Most sub-sectors within the industry recorded negative returns during the same period, with the vaccine and pharmaceutical distribution sectors showing the highest gains of 2.87% and 2.33%, respectively, while offline pharmacies and medical research outsourcing experienced declines of 3.95% and 3.11% [11][12]. - Approximately 57% of stocks in the industry recorded positive returns, with notable performers including Hezhong China, which saw a weekly increase of 115.96% [15][12]. Summary by Sections 1. Market Review - The SW pharmaceutical and biotechnology industry lagged behind the CSI 300 index, with a decline of 0.61% from October 24 to November 6, 2025 [10]. - Most sub-sectors recorded negative returns, with vaccines and pharmaceutical distribution leading in gains [11]. - About 57% of stocks in the industry had positive returns, with significant fluctuations among individual stocks [15]. 2. Industry News - The 11th batch of national drug centralized procurement results was announced, involving 55 varieties and 445 companies, with a selection rate of 57% [21]. - The new procurement rules emphasize clinical stability, quality assurance, and higher standards for bidding companies [21]. 3. Company Announcements - Yekang Pharmaceutical announced that its subsidiary received approval for clinical trials of YKYY013 injection for chronic hepatitis B treatment [22]. 4. Industry Outlook - The report suggests focusing on investment opportunities in innovative drugs and sectors with expected business development catalysts, including medical devices and traditional Chinese medicine [25]. - Key companies to watch include Mindray Medical, Yifeng Pharmacy, and Aier Eye Hospital, among others [26].

Group 1 - The core viewpoint of the news is that NuoVas has experienced fluctuations in its stock performance and financing activities, indicating a high level of trading activity and potential investor interest [1][2]. - On November 6, NuoVas' stock price decreased by 0.61%, with a trading volume of 32.48 million yuan. The financing buy-in amount was 2.79 million yuan, while the financing repayment was 2.27 million yuan, resulting in a net financing buy-in of 0.52 million yuan [1]. - As of November 6, the total balance of margin trading for NuoVas was 99.09 million yuan, with the financing balance accounting for 1.08% of the circulating market value, indicating a high level compared to the past year [1]. Group 2 - NuoVas, established on March 16, 2012, and listed on November 15, 2021, focuses on the research and development of functional proteins and high molecular organic materials, with a revenue composition of 81.86% from biological reagents, 9.99% from diagnostic reagents, and 3.15% from consumables [2]. - For the period from January to September 2025, NuoVas reported a revenue of 0.952 billion yuan, a year-on-year decrease of 3.40%, and a net profit attributable to shareholders of 6.62 million yuan, down 63.57% year-on-year [2]. - NuoVas has distributed a total of 0.731 billion yuan in dividends since its A-share listing, with 0.611 billion yuan distributed over the past three years [3].

Policy Developments - The National Medical Insurance Administration has initiated a pilot program for intelligent review of the entire process of medical insurance management, aiming to enhance the review capabilities and ensure the sustainable operation of medical insurance funds through the integration of AI technology [2]. Industry Developments - Chongqing has introduced measures to support high-quality development of innovative drugs, emphasizing the role of artificial intelligence in drug innovation and the establishment of a public service platform for "AI + pharmaceuticals" [3][4]. - Shanghai Pharmaceuticals has received FDA approval for its clopidogrel tablets, which are expected to generate approximately $1.284 billion in sales in the U.S. market in 2024, marking a significant opportunity for the company to expand its overseas market presence [6]. - NuoVation has obtained two medical device registration certificates for adenovirus antigen test kits, which are classified as Class III medical devices, indicating a step forward in the company's product offerings [7]. - Renfu Pharmaceutical has received approval for clinical trials of its HWH217 tablets, aimed at treating pulmonary arterial hypertension, with a total R&D investment of approximately 6 million yuan [8]. Capital Market - Pulsecare has successfully completed a financing round of over 100 million yuan, indicating strong investor interest in cardiovascular treatment technologies [10]. - Sunshine Nuohua has completed a share purchase plan by its associated company, acquiring 612,638 shares, which represents 0.55% of the total share capital, with an investment exceeding 28 million yuan [11]. Major Industry Events - The first batch of ovarian cancer treatment drugs has cleared customs in Beijing, marking a significant step in ensuring nationwide supply for this new treatment [13]. - Research from the Beijing Brain Science and Brain-like Research Institute has identified a new mechanism for treating depression, which could lead to the development of new antidepressant strategies with fewer side effects [14]. Regulatory Updates - Asia-Pacific Pharmaceutical has received a notification that its application for the consistency evaluation of diltiazem hydrochloride tablets has been rejected due to insufficient evidence supporting bioequivalence, indicating challenges in the drug development process [16].

Core Viewpoint - Novogene announced that its wholly-owned subsidiary, Nanjing Novogene Medical Technology Co., Ltd., has recently received two Medical Device Registration Certificates from the National Medical Products Administration [2] Group 1 - The company has achieved regulatory approval for its medical devices, which may enhance its market position and product offerings [2] - The issuance of these certificates indicates compliance with national standards, potentially leading to increased trust from healthcare providers and patients [2]

证券代码：688105 证券简称：诺唯赞 公告编号：2025-048 南京诺唯赞生物科技股份有限公司 关于自愿披露全资子公司取得医疗器械 注册证的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性依法承担法律责任。 南京诺唯赞生物科技股份有限公司（以下简称"公司"）全资子公司南京诺 唯赞医疗科技有限公司于近日收到国家药品监督管理局颁发的 2 项《医疗器械注 册证》，具体情况如下： 一、产品注册相关情况 （一）医疗器械注册证基本信息 | 序 | 名称 | 注册证编号 | | | | 注册分类 | 注册证 | | 预期用途 | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 号 | | | | | | | 有效期至 | | | | 1 | 腺病毒抗原检测试剂盒（胶体金法） | 国 | 械 | 注 | 准 | Ⅲ类 | 2030 年 | | | | | | 20253402230 | | | | | 11 月 3 | 日 | 体外定性检测人 | | 2 | 腺病毒抗 ...

Core Viewpoint - The company has received two medical device registration certificates from the National Medical Products Administration for its adenovirus antigen test kits, enhancing its competitive position in the respiratory pathogen detection market [1] Group 1: Product Development - The company’s subsidiary, Nanjing Novogene Medical Technology Co., Ltd., has developed two adenovirus antigen test kits: one using colloidal gold method and the other using quantum dot fluorescence immunochromatography method [1] - These test kits are designed for auxiliary diagnosis of respiratory adenovirus infections, which are particularly harmful to children under five years old [1] Group 2: Market Positioning - The approval of the adenovirus antigen test kits complements the company's existing rapid detection solutions for respiratory pathogens, catering to various clinical needs and application scenarios [1] - The company’s quantum dot platform, combined with already certified influenza A/B antigen and respiratory syncytial virus antigen tests, enables automated and high-sensitivity detection of five core respiratory pathogens [2] - The company’s product offerings meet the rapid testing needs of grassroots medical institutions, customs, and airports, enhancing its market reach [2]