于往绩记录期间，悦康药业多款旗舰产品凭借良好的市场接受度为公司带来收入及现金流，包括：悦康通®(银杏叶提取物注射液)在中国的医院覆盖面广 泛，包括三级及二级医院，用于管理脑血管和外周血管障碍。爱力士®(枸橼酸爱地那非片)在中国的泌尿科和男科环境中用于处方，治疗男性勃起功能障 碍。立卫克®(奥美拉唑肠溶胶囊)、悦达宁®(盐酸二甲双胍缓释片)等其他关键产品进一步扩大了公司在主要治疗领域的覆盖面。悦康药业也销售具有广泛 标示适应症的头孢菌素抗生素。 2025年12月29日，来自北京的悦康药业集团股份有限公司 Youcare Pharmaceutical Group Co., Ltd.(以下简称"悦康药业")在港交所递交招股书，拟香港主板 IPO上市。 悦康药业(688658.SH)，于2020年12月24日在A股上市，截至12月29日收市，总市值约人民币104亿元。 悦康药业招股书链接： https://www1.hkexnews.hk/app/sehk/2025/108009/documents/sehk25122901955_c.pdf 主要业务 悦康药业，成立于2001年，作为一家生物制药公司，拥有多元、经市 ...

据港交所12月29日披露，悦康药业集团股份有限公司(简称：悦康药业(688658.SH))向港交所主板提交上市申请，中信证券为其独家保荐人。 公司简介 招股书披露，悦康药业是一家生物制药公司，专注于研究、开发、生产和商业化四种模式的疗法：寡核苷酸、信使核糖核酸(mRNA)疫苗、多肽和中药创新 药。公司利用商业化产品组合、跨模态研发技术平台和能力、药品生产质量管理规范(GMP) 认证的生产系统及遍布全国的商业化网络等综合优势，为拥有 大量未满足需求及长期增长潜力的主要治疗领域推进候选产品的差异化创新管线。 | | | | 截至12月31日止年度 | | | | | 截至7月31日止七個月 | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | 2022年 | | 2023年 | | 2024年 | | 2024年 | | 2025年 | | | | (人民幣于元) | 8 | (人民幣于元) | ક | (人民幣于元) | હ | (人民幣于元) | હુર | (人民幣于元) | 多 | | | | | | | ...

智通财经APP获悉，据港交所12月29日披露，悦康药业集团股份有限公司(简称：悦康药业(688658.SH))向港交所主板提交上市申请，中信证券为其独家保荐 人。 公司简介 招股书披露，悦康药业是一家生物制药公司，专注于研究、开发、生产和商业化四种模式的疗法：寡核苷酸、信使核糖核酸(mRNA)疫苗、多肽和中药创新 药。公司利用商业化产品组合、跨模态研发技术平台和能力、药品生产质量管理规范(GMP) 认证的生产系统及遍布全国的商业化网络等综合优势，为拥有 大量未满足需求及长期增长潜力的主要治疗领域推进候选产品的差异化创新管线。 公司多款旗舰产品凭借良好的市场接受度为公司的收入及现金流带来重要贡献，为持续研发投资和产能扩张提供财务基础。悦康通® （银杏叶提取物注射 液）在中国的医院覆盖面广泛，包括三级及二级医院，用于管理脑血管和外周血管障碍。爱力士® （枸橼酸爱地那非片）在中国的泌尿科和男科环境中用 于处方，治疗男性勃起功能障碍。立卫克® （奥美拉唑肠溶胶囊）和悦达宁® （盐酸二甲双胍缓释片）等其他关键产品进一步扩大了公司在主要治疗领域 的覆盖面。公司亦销售具有广泛标示适应症的头孢菌素抗生素。 公司的管线包括创新 ...

经营业绩方面，公司实现规模与效益双丰收。2024年营收突破30亿元，2025年前三季度实现营收25亿 元，同比增长14%，归母净利润3.6亿元，同比增长46%。 于2010年登陆深交所创业板的瑞普生物，是A股首家专注兽药领域的动保上市公司，行业市占率国内第 一。 "十四五"是瑞普生物实现跨越式发展的五年。资本市场运作方面，2021年公司完成13.36亿元定向增 发，为产业链升级注入活水；2025年运用募集资金战略布局生物制造产业化项目，为未来增长再添动 力。 产业布局方面，公司构建起覆盖8省市12个规模化生产基地，形成生物制品、药物制剂、饲料添加剂、 宠物健康四位一体的全产业链格局，产品远销全球50余个国家和地区。2024年，公司宠物供应链营收 6.33亿元，同比增长37.66%，自主研发的"瑞喵舒"猫三联疫苗打破进口垄断。 研发创新是公司竞争力的源泉。"十四五"时期，公司年均研发投入超2亿元，研发投入占比达7.76%，搭 建6个国家级创新平台，截至目前累计获得121项新兽药注册证书，授权专利330项。2025年公司获得猪 流行性腹泻病毒mRNA疫苗临床批件，这是全球第一个食品动物用mRNA疫苗的临床批件。 ...

于2010年登陆深交所创业板的瑞普生物（300119），是A股首家专注兽药领域的动保上市公司，行业市 占率国内第一。 产业布局方面，公司构建起覆盖8省市12个规模化生产基地，形成生物制品、药物制剂、饲料添加剂、 宠物健康四位一体的全产业链格局，产品远销全球50余个国家和地区。2024年，公司宠物供应链营收 6.33亿元，同比增长37.66%，自主研发的"瑞喵舒"猫三联疫苗打破进口垄断。 研发创新是公司竞争力的源泉。"十四五"时期，公司年均研发投入超2亿元，研发投入占比达7.76%，搭 建6个国家级创新平台，截至目前累计获得121项新兽药注册证书，授权专利330项。2025年公司获得猪 流行性腹泻病毒mRNA疫苗临床批件，这是全球第一个食品动物用mRNA疫苗的临床批件。 展望未来，瑞普生物相关负责人表示，公司将锚定"中国动保行业第一、世界前五"的战略目标，深化科 创驱动，攻坚合成生物、mRNA疫苗、基因工程等前沿赛道，加速生物制造产业化落地，打造全球领先 的动保创新高地；拓展全球布局，深耕"一带一路"市场，让中国动保品牌走向世界舞台中央；完善"疫 苗—药品—保健品—医疗服务"生态闭环，创新生态范式，引领中国宠物 ...

Group 1 - The company, Shiyao Innovation, has submitted a listing application to the Hong Kong Stock Exchange, with CITIC Securities as its sole sponsor [1] - The company focuses on innovative therapies targeting unmet clinical needs in significant disease areas such as oncology, autoimmune diseases, and infectious diseases [1] - The company plans to commercialize two antibody drugs in the second half of 2024, including a first-class innovative drug and a biosimilar [1] Group 2 - Since its establishment in 2006, the company has specialized in the research and production of high-quality caffeine, becoming the largest producer of chemically synthesized caffeine globally [1] - The company expanded its main business into the health food sector in 2016, launching a comprehensive range of health food products, with its trademark recognized as a famous Chinese brand [2] - The global and Chinese pharmaceutical markets are experiencing significant growth, with the ADC market in China expected to expand from RMB 3.9 billion in 2024 to RMB 158.6 billion by 2035 [2]

Company Overview - The company, Shiyao Innovation Pharmaceutical Co., Ltd. (石药创新), has submitted a listing application to the Hong Kong Stock Exchange, with CITIC Securities as the sole sponsor [1] - The company focuses on the research, production, and commercialization of biopharmaceuticals, functional raw materials, and health foods [4] Business Development - In 2024, the company acquired control of Giant Bio, expanding its main business into the biopharmaceutical sector, marking a key step in its strategic transformation [5] - The company is developing innovative therapies targeting unmet clinical needs in significant disease areas such as tumors, autoimmune diseases, and infectious diseases [5] - The company has a strong pipeline with 15 drugs in clinical or late-stage development, including 9 ADC drugs and 1 mRNA vaccine [5] Financial Performance - The company's revenue for the fiscal years 2022, 2023, 2024, and the seven months ending July 31, 2025, were approximately RMB 2.838 billion, RMB 2.539 billion, RMB 1.980 billion, and RMB 1.241 billion respectively [9] - The company's profit for the same periods was approximately RMB 294 million, RMB 126 million, a loss of RMB 304 million, and a loss of RMB 226 million respectively [10] - The gross profit margin for the fiscal years 2022, 2023, 2024, and the seven months ending July 31, 2025, were approximately 46.8%, 45.6%, 41.8%, and 38.3% respectively [11] Industry Outlook - The global pharmaceutical market is expected to grow from USD 1,324.5 billion in 2019 to USD 1,542 billion in 2024, with a compound annual growth rate (CAGR) of 5.0% from 2024 to 2030 [13] - The global oncology drug market is projected to grow from USD 143.5 billion in 2019 to USD 253.3 billion in 2024, with a CAGR of 12.0% [14] - The global antibody drug market is expected to expand from USD 163.8 billion in 2019 to USD 254.3 billion in 2024, with a CAGR of 9.2% [15]

Company Overview - The company, Shiyao Innovation Pharmaceutical Co., Ltd. (stock code: 300765.SZ), has submitted a listing application to the Hong Kong Stock Exchange, with CITIC Securities as the sole sponsor [1] - The company focuses on the research, production, and commercialization of biopharmaceuticals, functional raw materials, and health foods [4] Business Development - In 2024, the company acquired control of Giant Bio, expanding its main business into the biopharmaceutical sector, marking a key step in its strategic transformation [5] - The company is engaged in the development of innovative therapies targeting unmet clinical needs in significant disease areas such as tumors, autoimmune diseases, and infectious diseases [5] - The company has a strong technical foundation in antibody drugs, antibody-drug conjugates (ADC), and mRNA vaccines, with plans to commercialize two antibody drugs in the second half of 2024 [5] Product Pipeline - As of December 1, 2025, the company has 15 drugs in clinical or late-stage development, including 9 ADCs and 1 mRNA vaccine [5] - The company’s mRNA vaccine products, including the first domestically developed COVID-19 mRNA vaccine, have been included for emergency use in China [5] Financial Performance - The company's revenue for the fiscal years ending July 31 for 2022, 2023, 2024, and the first seven months of 2025 were approximately RMB 2.838 billion, RMB 2.539 billion, RMB 1.980 billion, and RMB 1.241 billion respectively [8] - The company's profit for the same periods was approximately RMB 294 million, RMB 126 million, a loss of RMB 304 million, and a loss of RMB 226 million respectively [8] - The gross profit margin for these years was approximately 46.8%, 45.6%, 41.8%, and 38.3% [9] Industry Outlook - The global pharmaceutical market is expected to grow from USD 1,324.5 billion in 2019 to USD 1,542 billion in 2024, with a compound annual growth rate (CAGR) of 5.0% from 2024 to 2030 [11] - The Chinese pharmaceutical market is projected to grow from RMB 1,629.7 billion in 2024 to RMB 2,129.7 billion in 2030, with a CAGR of 4.6% from 2024 to 2030 [11] - The global oncology drug market is expected to expand from USD 143.5 billion in 2019 to USD 253.3 billion in 2024, with a CAGR of 12.0% [12] Market Position - The company is positioned as a significant player in the biopharmaceutical sector, focusing on innovative therapies and addressing unmet clinical needs [5][11] - The company has established a solid partnership with leading beverage companies, leveraging its expertise in caffeine production and health food products [6]

The Stock Exchange of Hong Kong Limited and the Securities and Futures Commission take no responsibility for the contents of this Application Proof, make no representation as to its accuracy or completeness and expressly disclaim any liability whatsoever for any loss howsoever arising from or in reliance upon the whole or any part of the contents of this Application Proof. Application Proof of CSPC Innovation Pharmaceutical Co., Ltd. 石藥創新製藥股份有限公司 (the "Company") (A joint stock company incorporated in the Pe ...

Group 1 - The core achievement of Kangtai Biologics is highlighted by the award of the "Outstanding Achievement Award" to Liu Jiankai, the Vice President of the company, recognizing significant contributions to the pharmaceutical field [1] - The 19th Pharmaceutical Development Award ceremony was held in Beijing, emphasizing the importance of breakthrough innovations in the medical and health sectors [1] - A vaccine innovation forum was co-organized by Kangtai Minhai, focusing on cutting-edge vaccine research and industrialization paths, featuring discussions from prominent experts in the field [1] Group 2 - Kangtai Minhai has undertaken nine national-level research projects and received four provincial and ministerial science and technology awards since its establishment [2] - The company has launched 12 vaccine products, including the domestically first four-component vaccine and the globally first dual-carrier 13-valent pneumococcal conjugate vaccine [2] - Kangtai Minhai is currently developing vaccines for Klebsiella pneumoniae, a five-component vaccine, and a hepatitis B treatment vaccine, aiming to become a leading enterprise covering the entire hepatitis B process [2]