香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完 整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或因倚賴該等內 容而引致的任何損失承擔任何責任。 本公告所作出的前瞻性陳述僅與本文作出該陳述當日的事件或資料有關。除法律規定外，於作出前 瞻性陳述當日之後，無論是否出現新資料、未來事件或其他情況，我們並無責任更新或公開修改任 何前瞻性陳述及預料之外的事件。請細閱本公告，並理解我們的實際未來業績或表現可能與預期有 重大差異。本公告中有關我們或任何董事及╱或本公司的意向的陳述或提述乃於本公告刊發日期作 出。任何該等意向均可能因未來發展而出現變動。 CStonePharmaceuticals 基石藥業 ( 於開曼群島註冊成立的有限公司 ) (股份代號：2616) 自願 公告 基石藥業宣佈普吉華®（普拉替尼膠囊）納入2025年國家醫保目錄 本公告乃由基石藥業(「本公司」連同其附屬公司統稱「本集團」或「基石藥業」)自願作出， 以使本公司股東及潛在投資者瞭解本集團的最新業務發展。 …………………………………………………………………………………………… 基石藥業今日 ...

Core Viewpoint - Junshi Biosciences (01877) saw a morning increase of over 3%, currently up 3.23% at HKD 24.28, with a trading volume of HKD 3.177 million. The company announced that its products, Toripalimab injection (brand name: Tuoyi, product code: JS001) and Engreztinib injection (brand name: Junshida, product code: JS002), have been included in the National Medical Insurance Catalog (2025) under Category B, effective January 1, 2026 [1]. Group 1 - The company has successfully added two new indications for Toripalimab and has included Engreztinib in the National Medical Insurance Catalog [1]. - All 12 approved indications for Toripalimab in mainland China have been included in the National Medical Insurance Catalog, making it the only anti-PD-1 monoclonal antibody in the catalog for the treatment of renal cancer, triple-negative breast cancer, and melanoma [1]. - Engreztinib is newly included in the catalog and is the only domestic PCSK9-targeted drug for patients intolerant to statins in the new version of the catalog [1].

Group 1: National Medical Insurance Directory Inclusion - Heng Rui Medicine has multiple drugs included in the 2025 National Medical Insurance Directory [1] - Xing Qi Eye Medicine has 39 products continuing to be included in the National Medical Insurance Drug Directory [1] - Bei Da Pharmaceutical has four products included in the National Medical Insurance Drug Directory [1] - Junshi Biosciences has added indications for Tuoyi® and included Junshida® in the National Medical Insurance Directory [1] - Zhongsheng Pharmaceutical's innovative drug Angladiwei tablets have been included in the National Medical Insurance Directory through negotiation [1] - Yiling Pharmaceutical's subsidiary has its exclusive product Qifang Nasal Tablets included in the National Medical Insurance Directory, totaling 12 exclusive patented traditional Chinese medicine products [1] - Aosaikang's product Liratinib tablets (Aoyi Xin®) has been included in the 2025 National Medical Insurance Directory [1] - Kanghong Pharmaceutical's product Kangbai Xip eye injection (Langmu) has been included in the 2025 National Medical Insurance Directory [1] - Dongcheng Pharmaceutical's Technetium-99m injection has been included in the medical insurance directory; its subsidiary has received clinical trial approval for 177Lu-LNC1009 injection [1] - Micron Biomedical's Sidabena tablets have been included in the National Medical Insurance Directory for regular Class B management [1] - Haichuang Pharmaceutical's Deuteroenzalutamide soft capsules have been included in the National Medical Insurance Directory for the first time [1] - Huadong Medicine's subsidiary products and cooperative products have been included in the National Medical Insurance and commercial insurance innovative drug directory [1] - Aidi Pharmaceutical's two anti-HIV innovative drugs continue to be included in the National Medical Insurance Directory through a simplified renewal process [1] Group 2: Corporate Developments - Hengyin Technology has signed a cooperation agreement with Muxi Co., focusing on the domestic GPU scenario [1] - Jia Jian Co. is planning a change in control, with stock resuming trading on December 8 [2] - Gu Ao Technology's actual controller is planning a change in control, leading to stock suspension [2] Group 3: Financial Performance - Tianbang Food reported a commodity pig sales revenue of 654 million yuan in November, a month-on-month increase of 7.66% [3] - Tian Ci Materials' controlling shareholder has committed not to reduce company shares [3]

Core Viewpoint - Kanghong Pharmaceutical's eye injection, Kangbaxip, has been included in the National Basic Medical Insurance, Maternity Insurance, and Work Injury Insurance Drug Catalog for 2025, reflecting recognition of its innovation and clinical value by the National Healthcare Security Administration [1] Group 1: Product Inclusion - Kangbaxip is the only domestic innovative drug covering four major indications for retinal diseases in the current catalog [1] - The inclusion in the regular catalog management will enhance the stability and accessibility of medication for patients [1] Group 2: Ongoing Clinical Trials - The company is actively conducting Phase III clinical trials for high-dose Kangbaxip [1] - Clinical trials for gene therapy drugs KH631 and KH658 are being carried out in both China and the United States [1] - The aim is to benefit more patients through high-quality innovation [1]

Core Insights - Hansoh Pharmaceutical (03692) announced that its innovative drug Amivantamab has successfully added two new indications to the 2025 National Medical Insurance Directory, which will be implemented on January 1, 2026 [1][2] Group 1: New Indications for Amivantamab - Amivantamab (brand name: 阿美乐) has received approval for two new indications for the treatment of adult non-small cell lung cancer (NSCLC) patients with specific EGFR mutations [1] - The new indications include treatment for patients who have previously undergone surgical resection and for those with locally advanced, unresectable NSCLC who have not shown disease progression during or after platinum-based chemotherapy [1] Group 2: Renewal of Other Drugs in the National Medical Insurance Directory - The drug Pemigatinib (brand name: 圣罗莱) has had its two indications renewed for inclusion in the 2025 National Medical Insurance Directory, specifically for treating anemia caused by chronic kidney disease [2] - The drug Adefovir Dipivoxil (brand name: 恒沐) has also been renewed for chronic hepatitis B treatment in adult patients [2] - Other innovative drugs such as Fluoromethylphenyl (brand name: 豪森昕福), Pegylated Liraglutide (brand name: 孚来美), and Inotuzumab Ozogamicin (brand name: 昕越) are currently under the National Medical Insurance Directory agreement until December 31, 2026 [2]

Core Viewpoint - The company, Silver诺医药-B (02591), has successfully included its core product, Isuparaglutide α, in the latest version of China's National Medical Insurance Drug List (2025 edition) for the treatment of Type 2 Diabetes (T2D) [1] Group 1 - The inclusion of Isuparaglutide α in the National Medical Insurance Drug List is a significant milestone for the company [1] - The updated National Medical Insurance Drug List will officially take effect on January 1, 2026 [1]

Core Viewpoint - Junshi Biosciences (01877.HK) announced that its products, Toripalimab Injection (brand name: Tuoyi, product code: JS001) and Engreitzumab Injection (brand name: Junshida, product code: JS002), have been included in the National Medical Insurance Catalog (2025) under Category B, effective January 1, 2026 [1] Group 1 - The inclusion of Toripalimab's two new indications and Junshida in the National Medical Insurance Catalog reflects the National Healthcare Security Administration's recognition of the clinical value, patient benefits, and innovation of these drugs [1] - Toripalimab is the only anti-PD-1 monoclonal antibody in the catalog approved for treating renal cancer, triple-negative breast cancer, and melanoma, with all 12 approved indications included [1] - Junshida is the first domestic PCSK9-targeted drug included in the new catalog for patients intolerant to statins [1] Group 2 - All four commercialized products of the company, including Tuoyi, Adalimumab Injection (brand name: Junmaikang, product code: UBP1211), Dexamethasone Hydrochloride Tablets (brand name: Mindewi, product code: VV116/JT001), and Junshida, are now part of the National Medical Insurance Catalog [2] - The inclusion in the catalog is expected to enhance affordability and accessibility for patients, promoting market expansion and increasing sales scale, positively impacting the company's long-term operational development [2] - The company will actively cooperate to implement the medical insurance policy, continue to advance hospital access, and expand coverage in core and broader markets to improve patient access to medications [2]

2025年国家医保目录、商保创新药目录将于2026年1月1日起执行。其中，2025年国家医保目录的具体医保支付标准、医保报 销细则、谈判药品的协议有效期等信息，须以国家医疗保障局等相关政府部门公示信息为准。 复星医药（600196）(02196)发布公告，根据2025年12月7日国家医疗保障局、人力资源社会保障部发布的《国家基本医疗保 险、生育保险和工伤保险药品目录(2025年)》(以下简称"2025年国家医保目录")以及首次发布的《商业健康保险创新药品目录 (2025年)》(以下简称"商保创新药目录")，上海复星医药(集团)股份有限公司及控股子公司/单位(以下简称"本集团")多款已上市 产品获首次纳入或涉及备注信息调整，现将有关情况公告如下： | 情形 | 药品名称 | 中国境内 | 中国境内 | | --- | --- | --- | --- | | | | 商品名 | 首次获批上市时间 | | 2025 年国家医保目录 | | | | | 新纳入 | 芦沃美替尼片 | 复迈宁 | 2025年5月 | | 枸橡酸伏维西利胶囊 | | 复妥宁 | 2025年5月 | | 吡仑帕奈口服混悬液 | | 奥捷宁 ...

微芯生物公告称，2025年12月7日，公司产品西达本胺片（爱谱沙®）纳入《国家医保目录》常规乙类 管理，编号932。医保支付范围包括复发或难治的外周T细胞淋巴瘤等患者。西达本胺是全球首个亚型 选择性组蛋白去乙酰化酶抑制剂，已在多地获批多项适应症。新版《国家医保目录》2026年1月1日起执 行，预计不会对本报告期经营业绩产生重大影响。 ...

东诚药业公告称，其全资子公司安迪科的锝替曲膦注射液被纳入《国家基本医疗保险、生育保险和工伤 保险药品目录（2025年）》。该产品仅用于诊断，可用于药物负荷和静息状态下心肌灌注显像。产品属 乙类注射剂，分类为心血管系统的诊断用放射性药物。《医保目录（2025年）》于2026年1月1日起执 行，暂不会对公司经营业绩构成重大影响。 ...