Market Overview - The market experienced a narrow fluctuation with the Shanghai Composite Index reaching a ten-year high of 3888.6 points before closing down 0.39% [1] - The total market turnover was 2.71 trillion yuan, significantly lower than the previous day's 3.18 trillion yuan [1] Medical and Pharmaceutical Sector Performance - The medical and pharmaceutical sectors saw a pullback after several days of gains, with the largest medical ETF (512170) down 1.27% and the only pharmaceutical ETF (562050) down 0.88% [1][2] - Major CXO stocks in the medical sector fell, with WuXi AppTec down 3.18% and Kelun Pharmaceutical down 6.59% [2] - Despite the decline, the medical ETF (512170) showed strong buying power with a significant increase in premium rates towards the end of the trading day, indicating robust demand [2] Investment Opportunities in Medical ETFs - The medical ETF (512170) closed at 0.388 yuan, still below the high of 0.396 yuan from September 2022, suggesting potential for upward movement [4] - The latest PE ratio for the index tracked by the medical ETF is 25 times, which is lower than 62% of the time over the past decade, indicating a favorable valuation for investment [4] - The ongoing bull market trend in A-shares may provide opportunities for undervalued sectors to catch up, particularly in the medical field [4] Pharmaceutical Sector Insights - The pharmaceutical sector is witnessing a divergence among leading innovative drug companies, with some stocks like Hengrui Medicine and BeiGene declining over 1%, while others like Baijitang and New Hope surged [7] - The pharmaceutical ETF (562050) reached a new high during the day but faced a quick pullback, although it ended with significant premiums, suggesting concentrated buying activity [7] - Among the 50 major pharmaceutical companies covered by the pharmaceutical ETF, 32 have reported positive earnings for the first half of the year, with 15 showing growth in net profit [8] Strategic Recommendations - Analysts recommend focusing on the medical ETF (512170) and its associated funds, emphasizing sectors like medical devices and services, which are highly correlated with AI healthcare [10] - The pharmaceutical ETF (562050) is highlighted as a unique investment vehicle focusing on leading pharmaceutical companies, with a significant allocation towards innovative drugs [11]

Core Insights - The Chinese innovative drug sector is on the rise and is currently in the early stages of realizing innovation成果 [1] - There remains a significant opportunity for independent development success and large-scale BD authorization transactions in the future [1] Industry Focus - In the oncology field, two main directions are highlighted: 1. The multidimensional iteration of ADCs (Antibody-Drug Conjugates), focusing on innovations in targets, antibody structures, and toxin combinations [1] 2. Innovations in the molecular components and spatial structures of immunotherapy, which may lead to breakthroughs with new combinations of ICI, TAA, cytokines, and TME-related chemotactic factors [1] Potential Products - The next potential blockbuster products may emerge from specific segments such as TCE (T-cell engagers), other bispecific/multispecific antibodies, and innovative ADCs, along with leading clinical enterprises in these fields [1]

国元证券指出，医保局座谈会明确了支持医疗器械行业"反内卷"、开放出海、差异化创新等原则，利好 行业高质量发展。集采价格有望进一步温和，促进企业盈利企稳提升；政策将激发医疗器械企业创新研 发积极性，新产品推出有望打开成长空间并加速国产替代；随着研发能力增强，政策助力中国创新药械 全球化发展，为企业开拓全球市场。医药生物行业方面，创新药进入成果兑现阶段，研发进展催化较 多，且不受贸易战影响，将持续作为投资主线；出海领域在新兴市场布局的企业发展潜力大。不同医药 领域的集采持续推进，部分细分赛道影响已出清，未来有望迎来新成长。 创业板医药ETF国泰（159377）跟踪的是创医药指数（399275），单日涨跌幅可达20%。该指数从创业 板市场中选取涉及生物医药、医疗器械等业务的上市公司证券作为指数样本，成分股覆盖创新药研发、 生物技术及医疗服务等行业，以反映创业板医疗健康相关上市公司证券的整体表现。 注：如提及个股仅供参考，不代表投资建议。指数/基金短期涨跌幅及历史表现仅供分析参考，不预示 未来表现。市场观点随市场环境变化而变动，不构成任何投资建议或承诺。文中提及指数仅供参考，不 构成任何投资建议，也不构成对基金业绩的 ...

Core Viewpoint - The Shanghai Stock Exchange Sci-Tech Innovation Board Biopharmaceutical Index has shown positive performance, with significant gains in constituent stocks, indicating a bullish trend in the biopharmaceutical sector [1][4]. Group 1: Index Performance - As of July 16, 2025, the Sci-Tech Innovation Board Biopharmaceutical Index increased by 0.21%, with notable rises in stocks such as Yifang Bio (+4.83%) and Nanwei Medical (+3.93%) [1]. - Over the past week, the Jiashi Sci-Tech Medical ETF has accumulated a rise of 4.76%, ranking first among comparable funds [1]. Group 2: Liquidity and Trading Activity - The Jiashi Sci-Tech Medical ETF recorded a turnover rate of 10.5% during trading, with a transaction volume of 21.6692 million yuan, reflecting active market participation [4]. - The average daily transaction volume for the Jiashi Sci-Tech Medical ETF over the past week was 31.1046 million yuan, also ranking first among comparable funds [4]. Group 3: Fund Growth and Performance - The Jiashi Sci-Tech Medical ETF has seen a significant growth of 12.5 million yuan in size over the past year, leading among comparable funds [4]. - The fund's net value increased by 41.50% over the past year, placing it in the top 17.15% among 2,909 index equity funds [4]. - The highest monthly return since inception was 23.29%, with the longest consecutive monthly gain being 5 months and an average monthly return of 7.43% [4]. Group 4: Major Stocks in the Index - As of June 30, 2025, the top ten weighted stocks in the Sci-Tech Innovation Board Biopharmaceutical Index accounted for 50.3% of the index, with leading companies including United Imaging Healthcare (8.97%) and BeiGene (7.05%) [4][6]. Group 5: Policy Developments - The innovative drug industry is set to benefit from favorable policies, with the adjustment of the national medical insurance drug catalog officially starting on July 11, 2025 [6]. - The National Healthcare Security Administration plans to announce the results of the drug catalog adjustments between October and November 2025 [6]. Group 6: Future Outlook - The year 2025 is anticipated to be significant for domestic innovative drugs entering the market, as companies transition from generic to innovative drugs following the "4+7" procurement policy implemented in 2018 [7].

Investment Rating - The report maintains a "Recommended" rating for the healthcare industry, indicating that the industry index is expected to outperform the benchmark index by more than 10% [7][24]. Core Insights - The pharmaceutical sector has shown a slight outperformance against the CSI 300 index, with the Shenwan Pharmaceutical Bio Index rising by 1.40% from June 9 to June 13, 2025, outperforming the CSI 300 by 1.65 percentage points [2][12]. - Year-to-date, the Shenwan Pharmaceutical Bio Index has increased by 9.33%, surpassing the CSI 300 by 11.13 percentage points, ranking 4th among 31 Shenwan primary industry indices [2][14]. - As of June 13, 2025, the valuation of the pharmaceutical sector stands at 28.29 times (TTM overall method, excluding negative values), with a valuation premium of 153.19% compared to the CSI 300 [2][17]. Summary by Sections 1. Market Performance - The pharmaceutical sector has outperformed the CSI 300 index, ranking 5th among 31 primary industry indices during the specified period [2][12]. - The sector's valuation reflects a significant premium over the broader market, indicating strong investor interest [2][17]. 2. Important Events - On June 13, 2025, a State Council meeting emphasized the need for enhanced evaluation of drug and consumable procurement policies, aiming for a more standardized and institutionalized approach to procurement [4][21]. - The meeting also highlighted the importance of improving public hospital compensation mechanisms and supporting pharmaceutical companies in enhancing innovation capabilities [4][21]. 3. Industry Perspective - The report notes that the procurement process in China's pharmaceutical sector has been ongoing for nearly a decade, expanding from solid oral formulations to include various drug categories and medical devices [5][22]. - There is a positive outlook for innovative drugs, overseas expansion, and sectors where procurement impacts have been cleared, suggesting potential growth opportunities [5][22]. - The report encourages attention to specific segments such as insulin and orthopedics, as well as certain generic drug companies, due to the ongoing acceleration of procurement processes [5][22].