Core Viewpoint - Yiling Pharmaceutical reported strong financial performance in the first half of 2025, with significant growth in revenue and net profit, driven by effective cost control and cash flow management [1] Financial Performance - The company achieved operating revenue of 4.04 billion yuan and a net profit attributable to shareholders of 669 million yuan, representing year-on-year growth of 26.03% [1] - The non-recurring net profit was 641 million yuan, with a year-on-year increase of 27.08% [1] - Operating costs decreased by 23.76%, and selling expenses fell by 15.28% [1] - Net cash flow from operating activities surged by 214.97% to 832 million yuan, with cash and cash equivalents at 1.003 billion yuan and a debt-to-asset ratio of 21.81% [1] Business Segments - The proprietary Chinese medicine segment remains the main revenue source, contributing 1.963 billion yuan from cardiovascular products, accounting for 48.6% of total revenue with a gross margin of 65.54% [3] - The company has 17 proprietary Chinese medicines, with 11 included in the 2024 National Medical Insurance Directory and 5 in the National Essential Drug List, covering eight major systems [3] - The chemical medicine segment is accelerating international expansion, with 4 innovative drug candidates in clinical stages and 15 ANDA products approved by the FDA [3][4] Research and Development - The company invests heavily in R&D, with an expenditure of 399 million yuan, representing 9.87% of revenue, and holds 870 valid patents, including 511 invention patents [6] - The establishment of a multi-level academic society system supports the research and promotion of the company's products, enhancing their market value [6]

Core Viewpoint - Yiling Pharmaceutical has demonstrated strong resilience with a return to double-digit profit growth in the first half of 2025, achieving a net profit of 669 million yuan, a year-on-year increase of 26.03% [1] Product Dimension - Yiling Pharmaceutical has established a diversified pharmaceutical health industry structure, driven by three main sectors: patented traditional Chinese medicine, chemical drugs, and health industry [2] - The patented traditional Chinese medicine segment remains the profit cornerstone, contributing 1.963 billion yuan in revenue, accounting for 48.6% of total revenue, with a gross margin of 65.54% [2] - The chemical drug business is crucial for international market expansion, with significant progress in the development of innovative drugs and a well-structured product pipeline [2] - The health industry aligns with the "Healthy China 2030" strategy, focusing on modern health needs and creating a unique health product system [3] Theoretical Dimension - The theory of "Luo Disease" serves as a foundational pillar for Yiling Pharmaceutical's product development and is a core competitive advantage [4] - The company has developed numerous innovative traditional Chinese medicines under this theoretical framework, enhancing its academic standing and market competitiveness [4] R&D Dimension - Yiling Pharmaceutical invested 399 million yuan in R&D in the first half of 2025, representing 9.87% of its revenue, positioning it at a leading level within the industry [6] - The company has established various innovation platforms and a comprehensive drug integration innovation technology system to support future R&D efforts [6][7] - The company holds 870 valid patents, including 511 invention patents, which will bolster its future product offerings and market competitiveness [8]

Core Viewpoint - The newly released guideline recommends the innovative traditional Chinese medicine, Shen Song Yang Xin Capsule, for the management of atrial fibrillation (AF), marking a significant milestone in integrating traditional Chinese medicine into modern cardiovascular treatment [1][2][14]. Group 1: Guideline Development and Significance - The guideline was developed by 67 experts from various medical associations, incorporating recent research and consensus on atrial fibrillation management [1]. - It emphasizes a comprehensive management approach for AF, integrating prevention, acute treatment, and long-term follow-up, highlighting the importance of multidisciplinary collaboration [2][3]. Group 2: Clinical Evidence and Recommendations - Shen Song Yang Xin Capsule is recommended for maintaining sinus rhythm in paroxysmal AF patients and reducing recurrence rates in patients post-radiofrequency ablation [1][4]. - The capsule's efficacy was supported by a multi-center randomized controlled trial involving 349 patients, showing a total effective rate of 62.3%, comparable to the drug Propafenone [5][7]. Group 3: Mechanism and Unique Advantages - The capsule operates through a unique formulation that addresses both rapid and slow heart rhythms, making it particularly suitable for elderly patients who may experience both types of arrhythmias [9][12]. - Its mechanism includes regulating ion channels and autonomic nervous functions, which helps improve cardiac conduction and stabilize heart rates [10][11]. Group 4: Future Implications and Research Directions - The inclusion of Shen Song Yang Xin Capsule in the guideline is expected to enhance the treatment options available for AF, particularly in the context of post-ablation management [14][15]. - Experts advocate for further high-quality clinical research to validate the efficacy of traditional Chinese medicine in treating arrhythmias, aiming for broader acceptance and integration into global treatment protocols [15][16].

7月11日晚，以岭药业发布公告称，该公司控股子公司以岭（澳门）有限公司收到澳门特别行政区政府 药物监督管理局（以下简称"澳门药监局"）核准签发的《中成药注册证明书》。 资料显示，2025年1月，以岭药业发布公告称芪防鼻通片获国家药品监督管理局批准上市。芪防鼻通片 作为中药1.1类创新药，组方基于过敏性鼻炎"肺脾两虚为本、外邪侵袭为标"病机理论化裁，融合经典 名方"玉屏风散"与"辛夷散"，并创新加入高良姜、蝉蜕等特色药材，肺脾同调、标本兼治，不仅为过敏 性鼻炎患者带来了新的治疗选择，也为中医药在耳鼻喉领域的应用注入了新的活力。 图片1.png 据悉，以岭药业以络病理论创新带动中医药产业化，运用现代高新技术研发创新中药。目前，以岭药业 拥有17个专利新药，其中11个为国家医保目录产品，5个为国家基药目录品种，尤其是心脑血管和呼吸 系统疾病用药品种处于行业领先地位。在研品种方面，2个中药已申报生产，6个中药处于临床阶段，并 有上百个院内制剂作为新药研发的"储备军"。此外，以岭药业申报注册的第一个经典名方品种半夏白术 天麻颗粒已获受理。 公告显示，芪防鼻通片是澳门药监局批准的第一个中成药创新药，用于治疗持续性变应性鼻 ...

Core Viewpoint - The announcement by the National Medical Products Administration regarding the optimization of clinical trial review and approval for innovative drugs is a significant positive development for the industry, particularly as it reduces the review time from 60 to 30 working days for innovative drug applications, including traditional Chinese medicine (TCM) [1] Group 1: Industry Overview - The recognition of TCM as an essential part of innovative drugs contrasts with the capital market's perception, which has not seen significant growth in TCM companies despite a surge in innovative drug stocks this year [1] - The modernization of TCM is gaining traction, supported by national policies, emphasizing the integration of traditional advantages with modern scientific techniques [3][4] Group 2: Company Profile - Yiling Pharmaceutical - Yiling Pharmaceutical is a leading innovative drug company with a focus on TCM, biopharmaceuticals, and health products, with TCM being the primary revenue and profit contributor [1] - As of the end of 2024, Yiling Pharmaceutical holds 17 patented TCM products covering eight major clinical disease systems, leading in the cardiovascular and respiratory disease treatment sectors [1] Group 3: Financial Performance - In 2024, Yiling Pharmaceutical's revenue from cardiovascular drugs exceeded 3.8 billion, while respiratory drugs accounted for less than 800 million, together representing over 70% of total revenue [9] - The company has experienced a decline in revenue over the past two years, primarily due to a significant drop in demand for its product Lianhua Qingwen post-pandemic [11] Group 4: Research and Development - Yiling Pharmaceutical has consistently ranked among the top in R&D investment within the A-share TCM sector, with annual R&D expenditures of approximately 895 million, 935 million, and 908 million over the past three years, representing 7.15%, 9.06%, and 13.94% of revenue respectively [5] - The company has achieved notable academic breakthroughs, including a landmark study published in a top medical journal demonstrating the efficacy of its product Tongxinluo in reducing cardiovascular events [6] Group 5: Growth Potential - Yiling Pharmaceutical's core competitive advantage lies in its founder's innovative theory on vascular diseases, which has attracted international research interest [12] - The company has five new drugs approved in the past five years, with four included in the medical insurance directory, indicating a strong pipeline for future growth [12] - The current market valuation of Yiling Pharmaceutical is estimated to be around 300 billion, with potential for significant appreciation as the market begins to recognize the value of innovative TCM [16]

Core Viewpoint - The article highlights the significant achievements of Yiling Pharmaceutical in the Chinese traditional medicine sector over the past five years, particularly its innovative drug development and successful market entries, marking a notable acceleration in the industry [2][4]. Group 1: Product Launches and Innovations - Yiling Pharmaceutical's proprietary traditional Chinese medicine, Qifang Bitong Pian, has been successfully registered and launched in Macau, becoming the first innovative traditional Chinese medicine approved in the region [2][3]. - Over the past five years, Yiling has launched five innovative traditional Chinese medicines, averaging one new drug per year, which is significantly higher than the industry average of less than ten new drugs annually [4][5]. - The company has a robust pipeline with two traditional medicines already submitted for production approval, six in clinical stages, and over a hundred hospital preparations as potential new drug candidates [5][6]. Group 2: Strategic Positioning and Market Expansion - Yiling's product strategy focuses on creating a comprehensive "big respiratory" product matrix that addresses multiple respiratory diseases, enhancing its market position [6][7]. - The company has expanded its focus from traditional respiratory treatments to include mental health products, responding to the growing demand for solutions to emotional and psychological issues [8][9]. - The launch of Tongluo Mingmu Capsules demonstrates the application of Yiling's "Luo Disease Theory" in treating complications related to diabetes, showcasing the versatility of traditional Chinese medicine in modern healthcare [9][10]. Group 3: Future Outlook and Business Strategy - Yiling Pharmaceutical is not only advancing its traditional Chinese medicine business but is also actively developing biopharmaceuticals and health products, creating a diversified portfolio that meets various consumer needs [11][12]. - The company aims to establish a new development pattern that integrates traditional Chinese medicine, biopharmaceuticals, and health industries, positioning itself as a comprehensive health solution provider [12].

Core Viewpoint - Yiling Pharmaceutical has successfully registered and launched its proprietary traditional Chinese medicine, Qifang Bitong Tablets, in Macau, marking a significant milestone in its internationalization process and showcasing its innovative capabilities in the traditional medicine sector [1][3]. Group 1: Product Innovation and Market Position - Over the past five years (2020-2024), Yiling Pharmaceutical has achieved a remarkable record of launching five new proprietary traditional Chinese medicines, averaging one new drug per year, which is significantly higher than the industry average of fewer than ten new approvals annually [2][4]. - The company has a robust pipeline with two traditional medicines already submitted for production approval, six in clinical stages, and over a hundred hospital preparations as potential new drug candidates [2][4]. - The recent launches, including Qifang Bitong Tablets and previous products like Lianhua Qingke Tablets and Tongluo Mingmu Capsules, illustrate Yiling's strategic focus on respiratory health and its ability to create a comprehensive product matrix addressing various respiratory diseases [4][5]. Group 2: Strategic Development and Market Expansion - Yiling Pharmaceutical's approach combines theoretical frameworks, clinical trials, and industrial capabilities, allowing it to innovate continuously within the same theoretical framework, particularly in the field of respiratory diseases [4][6]. - The company is expanding its product offerings beyond respiratory health to include mental health solutions, such as Yishen Yangxin Anshen Tablets for insomnia and Jiejing Chufan Capsules for mild to moderate depression, tapping into the growing demand for mental health treatments [6][7]. - Yiling's product innovation strategy reflects a shift from single blockbuster products to a multi-disease treatment approach, enhancing its market presence and addressing a broader range of health needs [5][6]. Group 3: Future Outlook and Business Model - Yiling Pharmaceutical is diversifying its business model by developing both traditional Chinese medicine and biopharmaceuticals, with several innovative drugs in clinical stages and a range of health products already launched [8][9]. - The company aims to create a comprehensive health solution that resonates with modern consumers, transforming traditional Chinese medicine into a globally understood health narrative [9].

Core Viewpoint - Beijing Yiling Pharmaceutical Co., Ltd. is leading the innovation in traditional Chinese medicine through the development of the "Luo Disease Theory" and the integration of AI technology in its production processes [4][10][17]. Group 1: Company Overview - Beijing Yiling Pharmaceutical was established in October 2006 and is a wholly-owned subsidiary of Shijiazhuang Yiling Pharmaceutical Co., Ltd., focusing on research innovation, market expansion, and international cooperation [3]. - The company has developed a comprehensive product system guided by the "Luo Disease Theory," which provides new diagnostic and treatment approaches for complex diseases [4][6]. Group 2: Product Development and Innovation - The company has created a series of clinically effective formulas based on the Luo Disease Theory, targeting major diseases such as cardiovascular diseases, diabetes, and respiratory diseases [6]. - Over 30 years, Yiling has developed an integrated model of traditional Chinese medicine innovation, successfully launching over ten patented traditional Chinese medicines, with five included in the national essential drug list and eleven in the medical insurance directory [6][9]. Group 3: Research and Clinical Trials - Yiling has introduced evidence-based medicine research methods into traditional Chinese medicine, conducting over 40 clinical studies to validate the efficacy of its products [9]. - The company is currently preparing for clinical trials of its Lianhua Yusheng Granules, with the trial expected to start in August 2025 [20]. Group 4: Technological Integration and Production Capacity - Yiling has completed the intelligent transformation of its production line for Lianhua Qingwen Granules, increasing its production capacity from 360 million bags to 1.08 billion bags [13][16]. - The company emphasizes the integration of smart manufacturing technologies to enhance production efficiency and quality control [13][16]. Group 5: Industry Impact and Future Plans - Beijing Daxing Biopharmaceutical Industry Base has become a key area for pharmaceutical health development, with Yiling positioned as an important innovation engine within this ecosystem [17]. - The company aims to deepen its collaboration in research and development, responding to the development plans of the Daxing Biopharmaceutical Industry Base, and continuously enhance its core competitiveness [20].

Core Viewpoint - The third China International Supply Chain Promotion Expo highlights the importance of industrial collaboration and international cooperation, showcasing innovative developments in the supply chain sector [1] Group 1: Innovation and Development Model - Yiling Pharmaceutical has established a unique "theory-clinical-research-industry-education" innovation development model, which integrates traditional Chinese medicine theory with clinical practices and research [1] - The company has undertaken over 60 national and provincial-level projects and holds more than 800 domestic and international patents, demonstrating its commitment to innovation [1] Group 2: Evidence-Based Research - Yiling Pharmaceutical is a pioneer in conducting internationally recognized evidence-based medical research, completing over 40 studies that are among the highest in quantity and quality in the industry [2] - Significant breakthroughs have been achieved in cardiovascular disease prevention, with studies showing a 41% reduction in diabetes risk and a 36% reduction in adverse cardiovascular events [2] Group 3: International Recognition - Research on Yiling's Qi Li Qiang Xin capsules published in the journal Nature Medicine indicates a 22% reduction in major composite endpoint events for heart failure patients [3] - The efficacy of the company's products is gaining international recognition, transitioning traditional Chinese medicine from "experience-based" to "evidence-based" practices [3] Group 4: Health Product Development - Yiling Pharmaceutical's health products, including anti-aging solutions, have attracted attention at the expo, showcasing the integration of technology in traditional medicine [4] - The company has developed over ten proprietary sub-health management products and has a pipeline of more than a hundred product concepts, catering to various health needs [5] Group 5: Market Response - Domestic and international customers have praised Yiling Pharmaceutical's series of health products, indicating strong market interest and acceptance [6]

Core Viewpoint - The third China International Supply Chain Promotion Expo showcases the development of traditional Chinese medicine (TCM) and its integration into modern health solutions, emphasizing the importance of quality in the TCM supply chain and innovation in product offerings [2][9]. Group 1: Supply Chain and Quality Management - The quality of traditional Chinese medicinal materials is fundamental to the industry's development, with Yiling Pharmaceutical implementing strict management protocols from seed to product [3]. - Yiling Pharmaceutical has established over 60 medicinal material cultivation bases across seven major production areas in China, covering tens of thousands of acres and involving over 40 varieties [3]. - The company’s model of "company + base + farmers" not only ensures the quality of medicinal materials but also provides stable income for local farmers, achieving a balance between environmental sustainability and economic growth [3]. Group 2: Innovation in Services and Products - Yiling Pharmaceutical has developed over 560 varieties of traditional Chinese medicine granules, streamlining the preparation process to enhance convenience for consumers [4]. - The company has created a complete industrial chain that includes cultivation, research, production, sales, and health services, reinforcing the foundation for high-quality development in TCM [4]. Group 3: Research and Development - Yiling Pharmaceutical has pioneered a unique innovation model that integrates theory, clinical practice, research, industry, and education, leading to the development of patented new drugs based on traditional theories [5]. - The company has undertaken over 60 national and provincial research projects and has received multiple national awards, showcasing its commitment to advancing TCM through scientific research [5][6]. Group 4: Health Product Development - Yiling Health, a subsidiary of Yiling Pharmaceutical, has developed a range of health products targeting various demographics, including fatigue relief for professionals and anti-aging formulas for seniors [8]. - The company has created over ten proprietary sub-health management products and has a pipeline of more than a hundred product concepts, demonstrating its adaptability in the health market [8]. Group 5: Global Outreach and Academic Exchange - Yiling Pharmaceutical has successfully entered international markets with its innovative TCM products, obtaining over a hundred international approvals for various health products [9]. - The company has been actively promoting TCM globally through academic exchanges and collaborations with international institutions, enhancing the recognition of TCM in the global academic community [9].