Market Overview & Macro Trends - S&P 500 rose 17 points or 0.2%, and the Dow gained over 100 points or 0.2%[7] - Tech sector declined by nearly 2% or more, while consumer staples, energy, and materials increased by 0.2% to 0.3%[8][9] - Long-term bond yields dropped significantly, with the 20-year yield falling 11 basis points and the 30-year yield falling 10 basis points[26] Corporate Performance & Stock Movements - Moderna shares surged 30% on the day and 491% year-to-date, backed by 13% of the float short, after a melanoma vaccine trial showed positive results[9][11][12] - Estee Lauder shares jumped 16%, marking its best day since November 2011, reporting fourth-quarter revenue of $3.6 billion and organic sales growth accelerating to 5%[14][15] - Twist Bioscience shares rose 22% to a more than five-year high after being chosen as an independent evaluator for Anthropic[16] - TJX Group shares fell about 4% as the MA Max segment's second-quarter comparable sales missed estimates[18][19] - Viking Holdings shares dropped about 8% amid investor concerns regarding low water levels in the Danube and Rhine rivers, despite booking 53% of its 2027 capacity[22][23] - White Fiber priced a private placement of $270 million in senior notes to build out AI infrastructure, with its market cap standing at about $1 billion and shares falling 21%[24][25]

$MRNA is onchain & trending with $28.3M traded in 24h.Moderna announced positive Phase 3 results today for its mRNA melanoma therapy.$MRNA is accessible as perpetual markets or RWAs on Trust Wallet. https://t.co/kbd6JzI1t1 ...

Result in high-risk patients validates decades of research into mRNA-based therapeutic cancer vaccines. https://t.co/ZfMfK735mM ...