Core Viewpoint - The document outlines the information disclosure management system of Wuxi WuXi AppTec Co., Ltd., emphasizing the importance of timely, accurate, and complete information disclosure to protect investors' rights and comply with relevant laws and regulations. Group 1: General Principles - The company establishes this system to regulate information disclosure behavior and strengthen management of disclosure affairs [1] - Information disclosure obligations must be fulfilled timely and accurately, ensuring that all investors receive the same information simultaneously [2][3] - Directors and senior management must diligently ensure the authenticity and completeness of disclosed information [4] Group 2: Disclosure Obligations - The company must disclose significant operational information that could impact investor decisions, adhering to the rules of the stock exchanges where its securities are listed [2][3] - Information disclosed in one market must also be disclosed in the other market if the company’s securities are traded in both [2][3] Group 3: Types of Reports - The company is required to prepare and disclose periodic reports, including annual, semi-annual, and quarterly reports, which must contain significant financial data and operational information [12][13] - The annual report must be disclosed within four months after the fiscal year-end, while the semi-annual report must be disclosed within two months after the first half of the fiscal year [7][13] Group 4: Content of Reports - The annual report must include basic company information, major financial data, stock and bond issuance details, and significant events affecting the company [16] - The semi-annual report should cover similar content but can be unaudited unless specific conditions apply [9][12] Group 5: Temporary Reports - The company must disclose any major events that could significantly affect the trading price of its securities immediately upon occurrence [29] - Major events include significant changes in business operations, major investments, and legal issues [29][30] Group 6: Management Responsibilities - The board of directors is responsible for ensuring timely disclosure of periodic reports and must approve the content before it is released [15][20] - The board secretary plays a crucial role in managing the information disclosure process and ensuring compliance with regulations [51][52] Group 7: Internal Controls - The company must have internal procedures for reporting and disclosing significant information, ensuring that all relevant parties are informed promptly [26][27] - The board secretary and company secretary are responsible for overseeing the compliance of information disclosure and managing the related documentation [30][31]

Core Points - The document outlines the rules for the Compensation and Assessment Committee of Wuxi AppTec Co., Ltd, aiming to enhance the management of compensation and assessment for directors and senior management [2][3] - The committee is established under the board of directors and is responsible for formulating assessment standards, reviewing compensation policies, and researching equity incentive plans [2][5] Group 1: General Provisions - The committee is created to improve corporate governance and is based on various legal and regulatory frameworks [2] - The committee consists of three directors, with a majority being independent directors [3] Group 2: Responsibilities and Authority - The committee's main responsibilities include developing compensation plans based on the roles and responsibilities of directors and senior management, and ensuring transparency in the compensation process [5][6] - The committee is tasked with reviewing and approving compensation for non-independent directors and senior management, ensuring fairness and alignment with contractual terms [6][12] Group 3: Decision-Making Procedures - The committee is supported by a working group responsible for preparing proposals and providing necessary operational data [8][15] - Meetings require a two-thirds attendance of committee members, and decisions must be approved by a majority [9][10] Group 4: Meeting Regulations - Meetings must be documented, including attendance and voting results, and records should be maintained for at least ten years [10][11][28] - The committee has the authority to invite other directors and senior management to meetings when necessary [10][11] Group 5: Final Provisions - The rules take effect upon approval by the board and replace any previous regulations [29][30] - Any unresolved matters will be governed by relevant laws and regulations [30][31]

Core Insights - The company achieved revenue of 3.188 billion yuan in H1 2025, representing an 18.2% increase, and a net profit attributable to shareholders of 617 million yuan, up 23.7% [1] - The company’s overseas revenue showed robust growth, particularly in Europe, where revenue reached 548 million yuan, growing over 200% year-on-year, accounting for 17% of total revenue [2] - The company’s emerging business segment is entering a high-growth phase, with revenue from chemical macromolecules expected to double for the full year [4] Financial Performance - In H1 2025, the company reported a gross margin of 43.5%, an increase of 1.3 percentage points, and an adjusted net profit margin of 21.4%, up 5.4 percentage points [2] - The company’s revenue for Q2 alone was 1.647 billion yuan, reflecting a 26.94% increase, with a net profit of 291 million yuan, up 33.94% [1] - The company has a strong order backlog of 1.088 billion USD, indicating high revenue certainty for the full year, with expected revenue growth of 13-15% [2] Business Segments - The small molecule CDMO business generated revenue of 2.429 billion yuan in H1 2025, showing a steady growth of 10.6% [3] - The emerging business segment reported revenue of 756 million yuan, a significant increase of 51.2%, with a backlog growth of over 40% [4] - The chemical macromolecule business saw revenue of 379 million yuan, growing over 130%, with expectations for continued strong growth in the second half of the year [4] Future Outlook - The company anticipates revenue for 2025-2027 to be 6.755 billion, 8.066 billion, and 9.488 billion yuan, with year-on-year growth rates of 16.37%, 19.40%, and 17.63% respectively [4] - Net profit projections for the same period are 1.155 billion, 1.377 billion, and 1.668 billion yuan, with growth rates of 21.70%, 19.24%, and 21.11% respectively [4]

Core Insights - The company reported a 62.2% year-on-year revenue growth in the first half of 2025, reaching 2.7 billion yuan, with a net profit increase of 52.7% to 746 million yuan, aligning with expectations [1] - The gross profit margin improved by 4.0 percentage points to 36.1% due to increased capacity utilization and rapid ramp-up of new capacity [1] - Revenue from overseas markets showed significant growth, with North America and Europe contributing 69% and 95% year-on-year increases, respectively, accounting for 74% of total revenue [1] Revenue Breakdown - Revenue from ADC projects reached 2.5 billion yuan, growing 60% year-on-year, while non-ADC project revenue was 196 million yuan, up 92% [1] - Revenue from IND pre-service and IND post-service was 1.12 billion yuan (up 71%) and 1.59 billion yuan (up 57%), representing 41% and 59% of total revenue, respectively [1] Market Position and Client Base - The company expanded its client base to 563, with 33% of revenue coming from the top 20 global pharmaceutical companies, and market share increased from 9.9% in 2022 to 22.2% in the first half of 2025 [2] - The total value of unfulfilled orders grew by 57.9% to 1.33 billion USD, indicating strong demand [2] Production Capacity Expansion - The company is implementing a "global dual-plant production" strategy, with a new facility in Wuxi operational since May 2025 and a Singapore plant expected to achieve GMP release in the first half of 2026 [2] - Capital expenditures are projected to reach 1.56 billion yuan in 2025, with significant investments in both the Singapore and Wuxi facilities [2] Earnings Forecast and Rating - The adjusted earnings per share forecast for 2025 has been raised from 1.22 yuan to 1.33 yuan, with subsequent years also seeing upward revisions [3] - The target price has been increased from 55.2 HKD to 70.3 HKD, indicating a potential upside of 29% [3]

Core Viewpoint - WuXi AppTec reported strong financial results for the first half of 2025, with significant revenue growth driven by an increase in customer and project numbers [1] Group 1: Financial Performance - The company achieved revenue of 2.701 billion yuan, representing a year-over-year increase of 62.2% [1] - Gross margin improved from 32.1% in H1 2024 to 36.1% in H1 2025, a year-over-year increase of 4.0 percentage points [1] - Net profit reached 746 million yuan, up 52.7% year-over-year, with adjusted net profit (excluding interest income and expenses) at 733 million yuan, a 69.6% increase [1] Group 2: Customer and Order Growth - The total number of global customers expanded to 563, with 64 new customers added in the first half of 2025 [1] - 13 out of the top 20 pharmaceutical companies globally in 2024 have established partnerships with WuXi AppTec [1] - The total number of integrated CMC (iCMC) projects reached 225, with 37 new iCMC projects signed in H1 2025, marking a historical high [1] Group 3: Market Position and Capacity Expansion - WuXi AppTec contributed over 75% of the total amount in global ADC licensing transactions exceeding 1 billion USD from January to July 2025 [2] - The company's market share increased from 9.9% in 2022 to 22.2% in H1 2025 [2] - The company is accelerating capacity construction, with the DP3 formulation workshop completing GMP release in July 2025 and the DP5 workshop under construction [2] Group 4: Revenue and Profit Forecast - Revenue projections for 2025-2027 have been raised to 5.906 billion, 7.440 billion, and 9.286 billion yuan, reflecting year-over-year growth rates of 45.75%, 25.96%, and 24.81% respectively [3] - Expected net profit for the same period is adjusted to 1.499 billion, 1.882 billion, and 2.364 billion yuan [3]

Core Viewpoint - Shanghai Haoyuan Chemexpress Co., Ltd. has implemented a "Quality Improvement, Efficiency Enhancement, and Return to Shareholders" action plan, focusing on enhancing operational efficiency and market competitiveness while ensuring shareholder returns through strategic initiatives and financial performance improvements [1][2]. Group 1: Business Focus and Strategy - The company is transitioning from a "business investment phase" to a "strategic harvest phase," accelerating its globalization process and expanding overseas revenue, which reached 560 million yuan, a year-on-year increase of 24.20% [2][3]. - The company has established an integrated service platform covering the entire pharmaceutical development lifecycle, from starting materials to intermediates, APIs, and formulations, enhancing its ability to support drug development [6][11]. - The company emphasizes high-value custom synthesis services in its life sciences reagent business, leveraging technical advantages to build differentiated competitive barriers in niche markets [3][11]. Group 2: Financial Performance - In the first half of 2025, the company achieved operating revenue of 1.311 billion yuan, a year-on-year increase of 24.20%, and a net profit attributable to shareholders of 152 million yuan, up 115.55% [2][3]. - The company reported an EBITDA of 260 million yuan, reflecting a 39.67% increase compared to the previous year [2]. Group 3: Research and Development - The company maintains a strong focus on R&D, with a research expense ratio exceeding 10% over the past three years, and has applied for a total of 426 patents, with 197 currently valid [11][12]. - The company is committed to integrating green chemistry principles into its drug development and production processes, enhancing efficiency and reducing costs through innovative technologies [12][22]. Group 4: Governance and Compliance - The company has streamlined its governance structure by reducing the board from nine to seven members, enhancing the professionalism and strategic alignment of its governance [14][15]. - The company has implemented a comprehensive upgrade of its governance systems to comply with new regulations, ensuring effective risk management and operational efficiency [16][17]. Group 5: Shareholder Returns and ESG Commitment - The company adheres to a dual-frequency dividend mechanism, optimizing shareholder returns in line with its three-year dividend plan, with cash dividends increasing compared to the previous year [19][21]. - The company actively promotes ESG principles, establishing a three-tier ESG management framework and releasing its second ESG report, showcasing its commitment to sustainable development [22].

Core Insights - Shanghai Hongbo Zhiyuan Pharmaceutical Co., Ltd. reported a significant increase in revenue and net profit for the first half of 2025, with revenue reaching 353 million yuan, a year-on-year growth of 32.73% [1] - The net profit attributable to shareholders was 24.76 million yuan, reflecting a substantial increase of 54.99% compared to the previous year [1] - The company achieved a net profit of 20.16 million yuan after deducting non-recurring gains and losses, marking a remarkable growth of 115.02% from 9.38 million yuan in the same period last year [1] - The net cash flow from operating activities was 39.43 million yuan [1] Business Operations - Hongbo Pharmaceutical provides comprehensive services for new drug research and commercialization for global pharmaceutical companies [1] - The company has maintained continuous investment and progress across multiple technology platforms during the reporting period [1] - Key advancements were noted in solid-state chemistry technology and process safety evaluation technology, which support the safe scale-up of projects from small trials to commercial production [1] Future Outlook - The company aims to continue focusing on technological innovation and platform development to meet the growing demands of global pharmaceutical clients [2]

Core Viewpoint - Kailaiying Pharmaceutical Group (Tianjin) Co., Ltd. has demonstrated strong growth and potential in the industry, as revealed during recent institutional research activities [1] Financial Overview - For the reporting period, the company achieved revenue of 3.188 billion yuan and a net profit attributable to shareholders of 617 million yuan, with a backlog of orders amounting to 1.088 billion USD [2] - Revenue increased by 18.2% year-on-year, while net profit grew by 23.7% [2] - Gross margin stood at 43.5%, up by 1.3 percentage points, and net profit margin was 19.4%, an increase of 0.9 percentage points [2] - Adjusted net profit margin reached 21.4%, reflecting a year-on-year increase of 5.4 percentage points [2] Business Segment Highlights - Small Molecule CDMO business generated revenue of 2.429 billion yuan, a 10.6% increase year-on-year, with a gross margin of 29.8%, up by 9.5 percentage points [3] - Emerging businesses, including peptides and small nucleic acids, saw revenue of 756 million yuan, representing a 51.2% year-on-year growth [3] - The company expanded its global market presence, adding over 150 new CDMO business clients during the reporting period [2] - Revenue from multinational pharmaceutical companies grew by 14.7%, while overseas revenue increased by 23.3% [2] - Revenue from small and medium-sized pharmaceutical companies rose by 21.6%, with domestic revenue up by 3.4% [2] Operational Developments - The small molecule business maintained steady growth despite industry challenges, with significant advancements in overseas capacity construction [3] - The company completed the delivery of 4 R&D projects and 1 production order for MNC clients, along with 285 QA audits [3] - The emerging business segment has a backlog of orders that increased by over 90% year-on-year, with over 40% from overseas [3] - The domestic market saw the approval of its first commercial peptide project in the weight loss sector [3] Future Outlook - For the first half of 2025, the company expects a revenue growth of 13% to 15% [4] - The company plans to enhance cost reduction and efficiency measures while increasing market expansion efforts, particularly in peptides, oligonucleotides, and conjugated drugs [4]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其 準確性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容 而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 Asymchem Laboratories (Tianjin) Co., Ltd. 凱萊英醫藥集團（天津）股份有限公司 茲載列本公司在深圳證券交易所網站刊登的以下資料中文全文，僅供參閱。 承董事會命 凱萊英醫藥集團（天津）股份有限公司 Hao Hong博士 董事長、執行董事兼首席執行官 中國天津，二零二五年八月二十五日 （於中華人民共和國註冊成立的股份有限公司） 於本公告日期，本公司董事會由董事長兼執行董事 Hao Hong 博士，執行董事楊蕊女 士、張達先生及洪亮先生，非執行董事 Ye Song 博士及張婷女士，以及獨立非執行董 事孫雪嬌博士、侯欣一博士及謝維愷先生組成。 （股份代號：6821） 海外監管公告 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B 條作 出。 凯莱英医药集团（天津）股份有限公司 2025 年半年度报告摘要 2025 年半年度报告摘要 1 凯莱英 ...

Core Viewpoint - The company has demonstrated significant revenue growth and has raised its full-year revenue guidance, reflecting confidence in the industry and its own future development [1][2]. Group 1: Financial Performance - In the first half of 2025, the company achieved revenue of 2.7 billion yuan, a year-on-year increase of 62.2%, and a net profit attributable to shareholders of 750 million yuan, up 52.7% year-on-year [1]. - The company's gross margin reached 36.1% in the first half of 2025, an increase of 4.0 percentage points year-on-year, driven by improved capacity utilization and operational efficiency [2]. Group 2: Market Position and Orders - The company's global market share is expected to rise to 22.2% by the first half of 2025, supported by a backlog of unfulfilled orders amounting to 1.33 billion USD, which is a 57.9% increase year-on-year [1]. - The company signed 37 new iCMC projects in the first half of 2025, setting a historical record, with new order amounts increasing by 48.4% year-on-year [1]. Group 3: Capital Expenditure and Growth Strategy - The company plans to increase long-term capital expenditures, with cumulative capital spending expected to exceed 7 billion yuan by 2029, focusing on expanding domestic and international production capacity [2]. - The company is actively developing new ADC and XDC businesses, completing over 2,300 early-stage research projects in the first half of 2025, with a significant portion focused on differentiated targets and new indications [2]. Group 4: Earnings Forecast and Valuation - The earnings per share forecasts for 2025-2027 have been adjusted to 1.29, 1.78, and 2.45 yuan, respectively, reflecting the company's strong growth potential as a leader in the global ADC CRDMO market [3]. - A target price of 65.82 HKD has been set using the DCF valuation method, maintaining a "buy" rating based on the company's long-term development potential [3].