半侵入式脑机接口通过将电极放置在硬膜上或者硬膜下采集大脑中的神经信号，由于神经信号随着传输距离迅速衰减，半侵入式脑机接口所采集信号的 时间和空间分辨率较低，难以提取精细的神经编码信息；与之相比，侵入式脑机接口直接将柔性电极植入脑组织内部，从而能够精准捕获具有高时空间 分辨率的单神经元动作电位（Spikes）。因此， 侵入式脑机接口不仅能实现对精细动作的实时、高精度解码，更在人机交互的信息传输速率（Bit Rate）有数量级的优势。 在侵入式脑机接口技术的全球竞争中，国外市场由马斯克创办的Neuralink率先领跑，国内则由智冉医疗凭借在核心技术领域的突破，叠加全链条自主 创新优势，成为国产侵入式脑机接口的领军企业。 已完成侵入式脑机接口产业链上中游的系统化布局。 本文为IPO早知道原创 作者｜ 罗宾 微信公众号｜ipozaozhidao 据IPO早知道消息，近日，国内侵入式脑机接口企业「智冉医疗」宣布完成3亿元人民币A+轮融资。本轮融资由中科创星领投，老股东君联资本、北京 市医药健康产业投资基金、IDG资本、顺为资本、联想创投、元生创投、红杉中国、美团龙珠、BV百度风投、杏泽资本、佳银资本持续跟投。本轮所募 ...

近日，国内侵入式脑机接口领军企业智冉医疗完成3亿元A+轮融资，本轮融资由中科创星领投，老股东君联资本、北京市医药健康产业投资基金、IDG资 本、顺为资本、联想创投、元生创投、红杉中国、美团龙珠、BV百度风投、杏泽资本、佳银资本持续跟投，这也是智冉医疗在半年内完成的第二轮融资 据了解，本轮融资将主要用于推进大规模临床试验与高通量柔性脑机接口产品迭代，加速该技术向临床应用落地。 来源：猎云网 从创立之初，智冉就坚定地走侵入式脑机接口技术路线，一方面是因为团队在侵入式脑机接口底层技术拥有深厚的技术积累；另一方面，是基于对行业终局 的深刻认知。脑机接口的未来是要实现人类大脑与外部设备之间高带宽的信息交互，从而将脑机接口从一种'弥补缺陷'的辅助工具，进化为人类通往高效人 机共生的核心底层技术，而只有侵入式脑机接口的路线能够实现这一跨越。 当前，植入式脑机接口已然形成了两种技术路线：半侵入式脑机接口和侵入式脑机接口。两者的本质区别在于电极与脑组织的物理位置关系，这直接决定了 神经信号的质量与应用上限。半侵入式脑机接口通过将电极放置在硬膜上或者硬膜下采集大脑中的神经信号，由于神经信号随着传输距离迅速衰减，半侵入 式脑机接口 ...

本轮融资主要用于推进大规模临床试验、高通量柔性脑机接口产品迭代，加速侵入式脑机接口技术的临 床应用落地。 可拉伸柔性电极植入大脑后的动态运动效果，企业供图 除了攻克柔性电极的难点，成立至今，智冉医疗在神经芯片、解码算法与电极植入机器人方面，也已经 完成研发布局。另外，自建了近2000㎡临床级微纳加工车间与GMP标准组装车间，实现临床级产品的 全链条自主可控。 去年8月，智冉医疗刚获得超3亿元A轮融资。时隔半年再次拿到大额融资，且老股东集体加注，可见投 资机构对智冉医疗侵入式脑机接口全栈能力的认可。 智冉医疗创始人、CEO宋麒告诉36氪，从创立之初，智冉就坚定做侵入式脑机接口，一方面是因为团队 在侵入式脑机接口底层技术拥有深厚的技术积累；另一方面，脑机接口的未来终局不会限于瘫痪患者脑 控外设、功能重建等，而要实现高效的人机信息互通，只有侵入式脑机接口能够做到真正高通量、高质 量的信号读写。 "柔性电极"这一核心部件，可谓是侵入式脑机接口赛道的关键入场券。人的大脑是非常柔软的组织，电 极植入大脑皮层后，如何确保长期不移位，并减少因免疫反应产生瘢痕、而导致脑电信号衰减等，成为 重要研发方向。 智冉医疗创始人方英在柔 ...

去年8月，智冉医疗刚获得超3亿元A轮融资。时隔半年再次拿到大额融资，且老股东集体加注，可见投资机构对智冉医疗侵入式 脑机接口全栈能力的认可。 智冉医疗创始人、CEO宋麒告诉36氪，从创立之初，智冉就坚定做侵入式脑机接口，一方面是因为团队在侵入式脑机接口底层技 术拥有深厚的技术积累；另一方面，脑机接口的未来终局不会限于瘫痪患者脑控外设、功能重建等，而要实现高效的人机信息互 通，只有侵入式脑机接口能够做到真正高通量、高质量的信号读写。 "柔性电极"这一核心部件，可谓是侵入式脑机接口赛道的关键入场券。人的大脑是非常柔软的组织，电极植入大脑皮层后，如何 确保长期不移位，并减少因免疫反应产生瘢痕、而导致脑电信号衰减等，成为重要研发方向。 智冉医疗创始人方英在柔性高通量电极与神经记录调控研究领域深耕多年，有多项突破性成果。研发的高通量"可拉伸柔性电 极"在植入大脑后，能够动态跟随大脑的搏动与颅内位移，确保了电极在脑组织中的长期稳定性。而且，相比于传统线性电极， 这款可拉伸电极在脑内也更加"柔软"，对脑组织的机械损伤更低。当前，智冉医疗已经研制出基于可拉伸柔性电极的高通量无线 侵入式脑机接口系统。 时 隔半年再次拿到大额融 ...

Core Insights - The article highlights a breakthrough in the field of invasive brain-machine interfaces (BMIs) achieved by a research team led by Fang Ying from Zhiren Medical, which successfully developed a high-throughput, stretchable flexible electrode that addresses the core challenges of traditional flexible electrodes in dynamic brain movements [2][12]. Group 1: Technological Advancements - The newly developed stretchable flexible electrode overcomes the limitations of traditional linear electrodes, which struggle to maintain stability during brain movements, thus providing a foundational solution for the long-term stability of invasive BMIs [2][4]. - The innovative design of the stretchable electrode allows it to dynamically adapt to the brain's pulsations and movements, ensuring long-term stability within the brain tissue [6][9]. - The research team demonstrated that the stretchable flexible electrode could achieve long-term stable recordings of neuronal activity in non-human primates, marking a significant milestone for clinical applications of invasive BMIs [8][12]. Group 2: Market Position and Future Implications - Zhiren Medical is positioned to lead the invasive BMI sector, with its breakthrough technology aligning with national strategic plans, thereby facilitating the transition from laboratory research to large-scale clinical applications [12][13]. - The advancements in invasive BMIs are expected to integrate seamlessly into everyday life, enhancing human-machine interactions in dynamic environments, such as extreme sports, without the risk of device displacement or brain injury [12][13]. - As the technology matures, China is poised to gain a significant competitive edge in the global invasive BMI market, leveraging its technological advancements to influence industry development [13].

2026年2月4日，博睿康技术（上海）股份有限公司正式向上海证监局提交上市辅导备案，辅导机构为中信证券，正式踏上A股IPO之路。 01） 不慌实验室 "第一股"竞争进入白热化 这家脱胎于清华大学神经工程实验室、深耕脑机接口十余年的企业，一跃成为资本市场焦点，也让国产脑机接口"第一股"的竞争进入白热化阶段。 自2015年天使轮融资启动，到2024年完成D轮融资，博睿康在近十年时间里累计完成6轮融资，松禾资本、熔拓兴兆、常州科教城产业基金、红杉中国等 知名机构密集入局，资本持续加注，印证了赛道热度与团队价值。 股权结构显示，公司控股股东为胥红来，持股13.90%，黄肖山持股11.85%，红杉恒辰持股8.94%，股权相对分散，但机构背书充足、科研背景扎实。 在脑机接口从科幻概念走向产业落地的关键节点，博睿康选择登陆资本市场，不仅是企业发展的重要里程碑，更成为观察中国脑机接口从技术研发走向商 业化、资本化的重要窗口，标志着国产脑机接口正式迈入资本市场主战场。 博睿康的核心价值，在于依托清华大学自主创新的脑机接口技术，构建"硬件+软件+算法"一体化能力，是国内少数实现从科研到临床全链条布局的脑机 接口企业。 公司专注神 ...

经济观察报记者刘晓诺 多动症干预领域，迎来了脑机接口的新方案。 近日，强脑科技发布了缺陷与多动障碍(ADHD)干预产品"专注欣"医疗版，这是一款脑机接口产品，包 括软件和硬件，均已获得二类医疗器械注册证。 其中，注意缺陷与多动障碍康复训练软件适用于6—12岁的ADHD儿童的康复辅助训练，医疗机构、康 复机构或家庭环境中均可使用。而搭载软件的硬件是一款前额叶单通道脑电采集器，采取非侵入式脑机 接口设计，比传统脑电设备更加轻便、易于佩戴，可更快速、更便捷地完成脑电采集与训练。 据强脑科技介绍，专注欣是一种安全、无创、无药的治疗方案。其技术原理是神经反馈训练，即利用大 脑神经元的可塑性，通过一定的训练手段(如奖励、强化机制)，帮助受训练者学会对目标脑神经活动的 自主调节和改善，达成修复或提升脑功能的目的。 专注欣包括用户信息模块、注意力训练模块、训练报告模块3个核心模块。软件里设置了各种有趣画 面，让孩子在高度训练的背景下来完成操作任务。游戏化的设计让孩子感到有趣，容易坚持。 基于严格诊断标准和三组对照研究结果，金星明认为，脑机接口与药物联合应用在症状改善和功能恢复 方面效果显著，且脑机接口技术对6—7岁低龄儿童表 ...

Group 1 - The core message emphasizes the importance of technological self-reliance and innovation for building a modern socialist country, as highlighted by President Xi Jinping during his visit to the National Innovation Park in Beijing [4] - The "14th Five-Year Plan" compared to the "15th Five-Year Plan" places a stronger emphasis on achieving a high level of technological self-reliance, aiming for a significant improvement in this area [5][6] - The visit underscores the need to enhance the innovation system, targeting breakthroughs in key core technologies and producing significant original and disruptive results to support high-quality economic and social development [6][7] Group 2 - The National Innovation Park has seen the establishment of 1,000 enterprises, with a focus on cutting-edge fields such as quantum information, 6G communication, and smart hardware, demonstrating the seamless integration of innovation and industry [7] - The development of international technology innovation centers in Beijing, Shanghai, and the Guangdong-Hong Kong-Macao Greater Bay Area aims to accelerate the formation of original innovation sources in China, serving as a strategic guide for building a strong technological nation [8] - The emphasis on enhancing the capabilities of international technology innovation centers reflects a commitment to fostering key technologies and empowering future industrial development, showcasing the potential for a more competitive innovation ecosystem [8]

智通财经APP获悉，浙商证券发布研报称，马斯克旗下Neuralink首款产品Telepathy预计在今年量产，目 前超10000人申请体验。Neuralink现估值超90亿美金，公司愿景是增加沟通带宽，提高交流效率，联接 人脑与AI。在未来，假设交流带宽将成为生物与技术之间的瓶颈，普通人将通过脑机接口实现与AI的 交流和复杂机械的操控。政策端，我国脑计划十年规划(2021-2030)进入下半场关键落地期，脑机接口成 为新质生产力未来产业之一，迎政策东风。建议关注脑机接口与大模型、具身智能技术深入融合。 浙商证券主要观点如下： Neuralink的首款产品Telepathy(心灵感应)预计在今年量产，目前超10000人申请体验 Telepathy聚焦"大脑功能正常，但运动/交流通路断裂"的重症群体，例如脊髓损伤、渐冻症患者。量产 的三个重要条件——N1性能提升、手术安全性提升、成本降低：1)预计2026年N1设备电极数量从1000 个增加到3000个，提升神经信号的接收量。2)针对手术流程，未来将直接穿过包裹大脑的硬脑膜植入电 极线的技术，可降低手术的侵入性，减少风险，降低感染隐患。3)第二代设备将电极植入速度 ...

Group 1: Core Perspectives - The emphasis on technology as the primary productivity force, talent as the primary resource, and innovation as the primary driving force is highlighted, with a focus on aligning with national strategic technology initiatives and enhancing international cooperation [1] - The goal is to build a distinctive highland for technological innovation, reform, and open cooperation, aiming to create a regional technology innovation center [8] Group 2: Technological Innovation Highland - Hainan is focusing on creating a globally influential technology innovation center by developing regional innovation systems that support high-quality local development [2] - The province has seen a significant increase in R&D funding, with a growth rate that has been the highest in the country for three consecutive years, and the number of national-level innovation platforms has doubled to 25 [2] - Hainan's comprehensive technology innovation index has improved, moving up six places to rank in the second tier nationally [2] Group 3: Integration of Technology and Industry - The strategy includes deep integration of technological innovation with industrial innovation, focusing on five key areas: agriculture, marine, aerospace, green technology, and digital technology [3] - The aim is to enhance the role of enterprises in technological innovation, fostering high-tech companies and unicorns through organized research and development [3] Group 4: Reforming the Technology System - Hainan is advancing reforms in the technology system, including optimizing management mechanisms and enhancing the collaborative innovation between government, industry, academia, and finance [4][5] - The province is implementing a series of institutional innovations to improve the efficiency of technology transfer and commercialization [5] Group 5: Open Cooperation in Technology - Hainan is actively engaging in international technology cooperation, establishing partnerships with 54 countries and regions, and hosting various international technology exchange events [6][7] - The province aims to leverage its unique advantages as a free trade port to attract innovative resources and enhance the internationalization of its technology work [7] Group 6: Talent Development - The construction of a "talent-rich island" and "technology innovation island" is a strategic task for the high-standard development of Hainan Free Trade Port, emphasizing the importance of talent in achieving these goals [8]