重组胶原蛋白

Search documents
创健医疗终止新三板挂牌、胶原蛋白巨头资本路径生变 2024年归母净利润腰斩
Xin Lang Zheng Quan· 2025-08-18 09:57
Group 1 - Jiangsu Chuangjian Medical Technology Co., Ltd. (Chuangjian Medical) has officially announced the termination of its listing on the National Equities Exchange and Quotations (NEEQ) after just 271 days, marking a rapid exit from the capital market [1][2] - The company initiated its listing process in early 2024, signed a contract with CITIC Securities, and officially listed on NEEQ on November 11, 2024, becoming the third collagen-restructured enterprise to do so [2] - The decision to withdraw may stem from a strategic shift, allowing the company to avoid the disclosure pressures and compliance costs associated with being a public company during a critical period of technological breakthroughs in collagen [2][3] Group 2 - Prior to its delisting, Chuangjian Medical received two core patent authorizations related to collagen technology, indicating a strong focus on innovation and potential market applications in the medical beauty sector [2] - The company has formed a strategic partnership with a leading global cosmetics OEM, Kosei Meishi, to develop new regenerative medical materials, suggesting a pivot towards business-to-business (B2B) opportunities [2][3] - The broader trend of medical companies exiting the NEEQ highlights a common challenge in the industry, where compliance costs and liquidity issues are increasingly burdensome, leading to a significant rise in delistings [3][4] Group 3 - The exit of Chuangjian Medical is part of a larger trend, with a 40% year-on-year increase in delistings among biomedicine companies on NEEQ in the first half of 2025, indicating a significant capital withdrawal from the sector [4] - The company’s strategy emphasizes enhancing product innovation and leveraging technological advancements to attract strategic investments, potentially positioning itself for future growth in higher-tier capital markets [4]
北交所规模最大定增预案出炉:钟睒睒34亿豪赌“胶原蛋白印钞机”
Xin Lang Zheng Quan· 2025-07-04 08:27
Core Viewpoint - Jinbo Bio plans to raise 2 billion yuan through a private placement to Yangshengtang, while its actual controller Yang Xia will transfer shares worth 1.403 billion yuan to Hangzhou Jiushi, leading to Zhong Shanshan indirectly controlling 10.58% of Jinbo Bio, becoming the second-largest shareholder [1] Group 1: Company Overview - Jinbo Bio, listed on the Beijing Stock Exchange in July 2023, is recognized as the "first stock of recombinant collagen" [1] - The company has experienced significant revenue growth, with projections showing an increase from 233 million yuan in 2021 to 1.443 billion yuan in 2024, and net profit rising from 57.39 million yuan to 732 million yuan during the same period, reflecting a compound annual growth rate of over 100% [1] - The core product, recombinant type III humanized collagen freeze-dried fiber (branded as Wei Yimei), is the first of its kind in China and has rapidly gained popularity since its approval in 2021, with sales expected to exceed 1 billion yuan in 2024 [1] Group 2: Strategic Partnerships and Market Position - The investment from Zhong Shanshan is expected to leverage Yangshengtang's strengths in branding, distribution, and funding to help Jinbo Bio overcome its current bottlenecks and achieve further growth [1] - Jinbo Bio's recombinant collagen technology complements Yangshengtang's existing business, potentially leading to new product developments in cosmetics, food, and pharmaceuticals [2] Group 3: Challenges and Risks - Despite high growth, Jinbo Bio faces challenges such as reliance on a single product, Wei Yimei, which is projected to account for over 70% of revenue in 2024 [2] - The company has low brand recognition compared to competitors like Huaxi Bio and Aimeike, primarily relying on medical beauty institutions for consumer recommendations, which limits direct consumer engagement [3] - The 2 billion yuan fundraising will be allocated to developing a humanized collagen FAST database and product development platform, with 11.5 billion yuan specifically for integrating AI technology to enhance research efficiency [3]
34亿,钟睒睒投了山西女首富
华尔街见闻· 2025-07-01 04:35
Core Viewpoint - The article discusses a significant strategic partnership between Jinbo Biological (832982.BJ) and Yangshengtang Co., Ltd., which involves a major share issuance and a substantial reduction in shareholding by Jinbo's controlling shareholder, Yang Xia [3][4][5][6]. Group 1: Strategic Partnership and Share Issuance - Jinbo Biological plans to issue 6.24% of its shares to Yangshengtang for an amount not exceeding 2 billion yuan, potentially marking the largest cash capital increase in the history of the Beijing Stock Exchange [5][21][22]. - Following the transaction, Yangshengtang will become the second-largest shareholder of Jinbo Biological, holding a total of 10.58% of the company's shares [23]. Group 2: Share Reduction by Controlling Shareholder - Yang Xia, the controlling shareholder of Jinbo Biological, will transfer 5% of her shares to a partnership controlled by Yangshengtang, with a total reduction amounting to 1.403 billion yuan, setting a record for the largest share reduction in the history of the Beijing Stock Exchange [6][18][20]. - This transaction is notable as it marks Yang Xia's first reduction of shares since the company's listing [16][18]. Group 3: Market Context and Implications - The total market capitalization of Jinbo Biological is approximately 40.959 billion yuan, representing 12.82% of the total market capitalization of 268 companies on the Beijing Stock Exchange [26][27]. - The article highlights the potential for increased sales and distribution capabilities for Jinbo Biological through the partnership with Yangshengtang, leveraging its extensive distribution network [11][34][35]. Group 4: Competitive Landscape and Future Prospects - Jinbo Biological faces increasing competition in the medical aesthetics market, particularly with its flagship product, Wei Yimei, as competitors like Juzhi Biological and Chuangjian Medical are entering the market [38][39]. - The partnership with Yangshengtang is seen as a strategic move to enhance Jinbo Biological's marketing and distribution efforts, particularly in skincare products, which currently represent a small portion of its revenue [40][41][42].
北交所的最大一笔「减持」来了
Hua Er Jie Jian Wen· 2025-06-30 15:09
Core Viewpoint - JINBO Biotech (832982.BJ), known as the "king of market value" on the Beijing Stock Exchange, is entering a significant strategic partnership with Yangshengtang Co., Ltd., owned by former Chinese billionaire Zhong Shanshan [1][4]. Group 1: Strategic Partnership and Share Issuance - JINBO Biotech will issue 6.24% of its shares to Yangshengtang for an amount not exceeding 2 billion yuan, potentially marking the largest cash capital increase in the history of the Beijing Stock Exchange [2][17]. - The controlling shareholder, Yang Xia, will transfer 5% of her shares to a subsidiary of Yangshengtang, with a total reduction amounting to 1.403 billion yuan, which is expected to set a record for the largest reduction by a controlling shareholder on the Beijing Stock Exchange [3][12]. Group 2: Market Impact and Future Prospects - Following the transaction, Yangshengtang will become the second-largest shareholder of JINBO Biotech, holding 10.58% of the total share capital post-issuance [18]. - The partnership is anticipated to enhance JINBO Biotech's channel sales capabilities, leveraging Yangshengtang's extensive distribution network through its subsidiary Nongfu Spring, a leading beverage company in China [7][30]. Group 3: Financial Performance and Valuation - As of June 30, JINBO Biotech's total market value reached 40.959 billion yuan, accounting for 12.82% of the total market capitalization of the Beijing Stock Exchange [21]. - The company's price-to-earnings ratio (PE) stands at 51 times, significantly higher than its peers, indicating a potentially favorable time for the controlling shareholder to reduce holdings [23]. Group 4: Growth Strategy and Product Development - JINBO Biotech aims to expand its production capacity and establish a broader sales and marketing system through this strategic cooperation, focusing on the consumerization of medical products and the lifestyle integration of technological products [27]. - The collaboration with Yangshengtang is expected to facilitate JINBO Biotech's entry into more market areas, particularly in skincare products, which currently represent a small fraction of its revenue compared to its medical device products [36].
钟睒睒,投了山西女首富
盐财经· 2025-06-30 09:42
Core Viewpoint - The article discusses the significant investment by Zhong Shanshan in Jinbo Biological, a rising player in the medical beauty industry, highlighting the strategic partnership and potential for business synergies in the field of recombinant collagen products [5][11][14]. Group 1: Investment Details - Jinbo Biological announced two transactions, including introducing Yangshengtang as a strategic investor, with a total transaction amount reaching 3.4 billion yuan [5][10]. - The company plans to issue up to 7.18 million shares to Yangshengtang, which would represent 6.24% of its pre-issue total share capital, aiming to raise no more than 2 billion yuan, potentially marking the largest cash capital increase in the history of the Beijing Stock Exchange [9]. - Yang Xia, the controlling shareholder, will transfer 5.75 million shares to Hangzhou Jiushi at a price of 243.84 yuan per share, totaling 1.403 billion yuan [10]. Group 2: Company Background - Jinbo Biological, founded by Yang Xia, focuses on recombinant collagen products and has achieved a market value of 40 billion yuan [7][12]. - The company has developed a range of products, including recombinant collagen injections, which have gained significant popularity in the medical beauty sector [24][25]. - As of the first quarter of 2025, Jinbo Biological had cash reserves of only 959 million yuan, indicating a need for new investment to expand production capacity [13]. Group 3: Market Potential - The medical beauty industry, particularly recombinant collagen, is experiencing rapid growth, with Jinbo Biological reporting a revenue of 1.443 billion yuan in 2024, a year-on-year increase of 84.92%, and a net profit of 732 million yuan, up over 140% [25]. - The gross profit margin for Jinbo Biological reached 92%, surpassing that of leading companies like Kweichow Moutai [25]. - The article emphasizes the strong consumer interest in beauty products, with recombinant collagen being positioned as a new trend in skincare, potentially rivaling hyaluronic acid [29][34].
暴涨超8%!钟睒睒拟大手笔入股
第一财经· 2025-06-27 13:04
Core Viewpoint - The article discusses the recent capital increase and strategic partnership of Jinbo Biological, a leader in recombinant collagen, with Yangshengtang, highlighting the financial implications and future growth potential in the collagen market [1][2]. Group 1: Capital Increase and Shareholder Changes - Jinbo Biological plans to issue up to 7.1756 million shares at a price of 278.72 yuan per share, raising a total of no more than 2 billion yuan, with 1.15 billion yuan allocated for the development of a humanized collagen FAST database and product development platform [1]. - Following the issuance, Yangshengtang will hold 5.87% of Jinbo Biological, making it the second-largest shareholder, while Yang Xia's stake will decrease to 50.73% [2][3]. - Yang Xia transferred 575.33 million shares (5% of total shares) to Hangzhou Jiushi at a price of 243.84 yuan per share, totaling 1.403 billion yuan [1][2]. Group 2: Strategic Cooperation and Market Position - Jinbo Biological and Yangshengtang signed a strategic cooperation agreement to enhance research and development collaboration, focusing on the application of collagen bio-materials in skincare, food, and pharmaceuticals [4][5]. - The partnership aims to leverage Yangshengtang's resources for brand promotion, channel management, and international expansion, aligning with Jinbo Biological's product offerings in anti-aging and medical aesthetics [5]. - Analysts note that the recombinant collagen industry is experiencing technological advancements and increasing consumer awareness, leading to accelerated commercialization [5].
“测不到胶原”风波发酵:巨子生物陷信任危机,重组胶原蛋白市场震荡
2 1 Shi Ji Jing Ji Bao Dao· 2025-05-26 12:09
Core Viewpoint - The controversy surrounding Juzhibio's flagship product, Kefu Mei, has raised significant concerns about the authenticity of its collagen claims, leading to a crisis of trust among investors and consumers [1][3][6]. Company Summary - Juzhibio, known as a leader in recombinant collagen, has faced allegations of product falsification, particularly regarding its Kefu Mei product, which reportedly contains only 0.0177% collagen, below the regulatory threshold of 0.1% [3][4]. - The company has stated that all its products are compliant with regulatory standards and have undergone rigorous quality checks [4][6]. - Following the controversy, Juzhibio's stock price fell by 4.04% to HKD 73.6, with a total market capitalization of HKD 788.19 billion as of May 26 [2]. Industry Summary - The demand for aesthetic products, including hyaluronic acid and collagen, has been rising, with major players like Juzhibio and Jinbo Bio seeing growth despite market challenges [2][9]. - The recombinant collagen market in China is projected to grow significantly, reaching CNY 585.7 billion by 2025, with a compound annual growth rate of 44.93% [10][12]. - The lack of standardized testing methods for collagen products has led to discrepancies in product claims and consumer trust issues, highlighting the need for regulatory frameworks in the industry [5][8][12].
重组胶原蛋白赛道捧出两位“首富”
经济观察报· 2025-05-14 11:40
Core Viewpoint - The article highlights the rapid growth and competitive landscape of the recombinant collagen protein industry, focusing on two key players: Juzhi Biotechnology and Jinbo Biotechnology, both of which have achieved significant market milestones and financial success in recent years [1][2][5]. Company Overview - Juzhi Biotechnology was established in 2000 and specializes in the research, production, and sales of recombinant collagen and other bioactive components. It went public on the Hong Kong Stock Exchange in November 2022, becoming the first stock in the recombinant collagen sector listed there [4][5]. - Jinbo Biotechnology was founded in 2008 and went public on the Beijing Stock Exchange in 2023, marking it as the first stock in the recombinant collagen sector listed on that exchange [1][5]. Financial Performance - In 2024, Juzhi Biotechnology reported a revenue of 5.539 billion yuan, a year-on-year increase of 57.2%, while Jinbo Biotechnology achieved a revenue of 1.443 billion yuan, with a remarkable growth rate of 84.92% [8]. - Juzhi Biotechnology's adjusted net profit was 2.152 billion yuan, up 46.5% year-on-year, and Jinbo Biotechnology's net profit reached 732 million yuan, soaring by 144.27% [8]. - Both companies maintained high gross margins, with Juzhi Biotechnology at 82.09% and Jinbo Biotechnology at 92.02% in 2024 [8]. Market Trends - The recombinant collagen market in China is projected to grow from 18.5 billion yuan in 2022 to 108.3 billion yuan by 2027, reflecting a compound annual growth rate (CAGR) of 42.4% [6]. - The increasing consumer demand and advancements in biotechnology are driving the rapid development of the recombinant collagen industry [6]. Competitive Landscape - The industry is becoming increasingly competitive, with established players like Huaxi Biotechnology and Aimeike entering the recombinant collagen market. New entrants are also attempting to reshape the market dynamics [8]. - Juzhi Biotechnology's revenue heavily relies on its core brand, Kefu Mei, which contributes over 80% of its total revenue [9]. Challenges and Risks - Juzhi Biotechnology faces challenges due to its reliance on a single brand and an increasing dependence on online sales channels, which accounted for 71.6% of total revenue in 2024 [9]. - Jinbo Biotechnology also has a high revenue concentration, with 78.17% of its revenue coming from a single medical device product line [10]. - Both companies are navigating a competitive environment where maintaining market position and expanding product lines are critical for future growth [11][14].
重组胶原蛋白赛道捧出两位“首富”
Sou Hu Cai Jing· 2025-05-13 23:55
Core Insights - The topic of "Northwest University Vice President Fan Daidi becomes the richest person in Shaanxi" has gained significant attention on social media, highlighting the wealth of Fan Daidi and her husband Yan Jianya, who own two listed companies: Juzhi Biotechnology and Triangle Defense [2] - According to the 2025 Hurun Global Rich List, Fan Daidi and her husband have a combined net worth of 31.5 billion yuan, surpassing other notable figures in the region [2] Company Overview - Juzhi Biotechnology, founded in 2000, specializes in the research, production, and sales of recombinant collagen and other bioactive components, and was listed on the Hong Kong Stock Exchange in November 2022 [3][4] - Fan Daidi, a co-founder of Juzhi Biotechnology, served as the executive director until July 2023 and has a long-standing affiliation with Northwest University, where she has held various academic positions [3][4] Market Dynamics - The recombinant collagen market is experiencing rapid growth, with a projected market size increase from 18.5 billion yuan in 2022 to 108.3 billion yuan by 2027, reflecting a compound annual growth rate (CAGR) of 42.4% [4] - Both Juzhi Biotechnology and Jinbo Biotechnology are showing high growth rates, with Juzhi's revenue reaching 5.539 billion yuan in 2024, a year-on-year increase of 57.2%, while Jinbo's revenue grew by 84.92% to 1.443 billion yuan [5] Financial Performance - Juzhi Biotechnology reported an adjusted net profit of 2.152 billion yuan in 2024, up 46.5% year-on-year, while Jinbo's net profit surged by 144.27% to 732 million yuan [5] - Both companies maintain high gross margins, with Juzhi's gross margin at 82.09% and Jinbo's at 92.02% in 2024 [6] Competitive Landscape - The competition in the recombinant collagen sector is intensifying, with established players like Huaxi Biotechnology and Aimeike entering the market, alongside new entrants like Hangzhou Meiliu Biotechnology, which has significantly reduced production costs [6][9] - Juzhi Biotechnology's revenue heavily relies on its core brand, Kefu Mei, which accounts for over 80% of its revenue, and the company is increasingly dependent on online sales channels, which constituted 71.6% of total revenue in 2024 [6][7] Product Development Challenges - Juzhi Biotechnology has plans to enter the recombinant collagen injection market, with two products expected to be approved in 2024, but currently, its registration is limited to dressing products [7][8] - Jinbo Biotechnology has achieved breakthroughs in the third-class medical device sector, holding all three existing registrations for recombinant collagen medical devices in China, but also faces challenges with revenue concentration [8][9]
美妆|重组胶原蛋白:供给创造需求,创新驱动成长,国内海外齐奔赴
中信证券研究· 2025-04-28 00:14
重组胶原蛋白行业在技术、工艺上持续进步,继I型、III型后在XVII型、IV型以及多型别组合方面再现突破;各龙头公司在结构解析、发酵制 备、产品化、商业化方面的闭环能力更为成熟。格局方面,各公司均综合布局"妆&二类械&消费/严肃医疗三类械",同时又在各自擅长的品类深 耕,差异化竞争。最后,中国重组胶原蛋白全球化提速,"原料、妆、械"全面出海。 ▍ 皮肤具备多种生理功能,胶原蛋白分布广且功效多样。 皮肤呈现层叠结构,由表皮、真皮、皮下组织构成。皮肤具有屏障、吸收、分泌和排泄、感觉、体温调节、物质代谢、免疫等多种功能,直接 参与全身的各种功能活动并维持内环境的稳定。人体内2 9种型别胶原蛋白,各型别功能和分布有所区别。目前人类研究发现的胶原蛋白共2 9 种,当前市场上开发和商业化较多的为I型和III型胶原蛋白。双光子显微成像等技术能够有效检验重组胶原蛋白透皮吸收情况。 文 | 徐晓芳 杜一帆 张琳 宋硕 徐嘉琪 皮肤生理功能梳理 | 序号 功能 | | 功能解析 | | --- | --- | --- | | 1 | 屏障功能 | 一方面,保护机体内各种器官组织免受外界环境中机械的、物理的、化学的和生物 | | ...