1H25，公司核药抗肿瘤板块收入4.22亿港币，剔除汇率影响同比+105.5%，主要由于国内易甘泰快速放 量。此外，报告期内易甘泰获FDA批准用于原发性肝细胞癌，成为全球首个获批原发性肝细胞癌和结直 肠癌肝转移的内放射治疗产品。RDC方面公司临床推进顺利，TLX-591CDx完成三期临床入组， TLX591、ITM-11等产品加入国际多中心III期临床试验，自研创新核药GPN02006亮相国际会议。 公司公布1H25业绩：收入61.07亿港币，同比+1.0%，剔除汇率影响同比+2.0%;归母净利润11.69亿港 币，超该行预期，主要由于收入超预期。 在创新和壁垒产品放量的支持下，公司上半年经营业绩稳健，体现良好的抗风险能力 智通财经APP获悉，中金发布研报称，由于1H25远大医药(00512)业绩体现了较好的抗风险能力，上调 2025年/2026年归母净利润预测3.3%/3.4%至19.1亿/21.0亿港币。当前股价对应2025年/2026年18.0倍/16.4 倍P/E。考虑到公司创新管线不断兑现，该行维持跑赢行业评级，上调目标价21.9%至11.7港币，对应 2025年/2026年21.7倍/19.8倍P ...

在创新和壁垒产品放量的支持下，公司上半年经营业绩稳健，体现良好的抗风险能力 根据公司公告，1H25公司持续推动创新结构转型，创新和壁垒产品收入占比约51%(vs去年同期 36.1%)。易甘泰、Lava、恩卓润/恩明润、能气朗、合心爽/合贝爽等产品快速增长。剔除第十批集采影 响，公司人民币口径收入同比增长约13.0%，支持收入实现可持续增长。 核药板块延续翻倍增长态势，创新核素偶联药物(RDC)管线进展丰富 中金发布研报称，由于1H25远大医药(00512)业绩体现了较好的抗风险能力，上调2025年/2026年归母净 利润预测3.3%/3.4%至19.1亿/21.0亿港币。当前股价对应2025年/2026年18.0倍/16.4倍P/E。考虑到公司创 新管线不断兑现，该行维持跑赢行业评级，上调目标价21.9%至11.7港币，对应2025年/2026年21.7 倍/19.8倍P/E，较当前股价有20.6%的上行空间。 中金主要观点如下： 1H25业绩超该行预期 公司公布1H25业绩：收入61.07亿港币，同比+1.0%，剔除汇率影响同比+2.0%;归母净利润11.69亿港 币，超该行预期，主要由于收入超预期。 关注 ...

Core Viewpoint - The company has achieved significant innovation progress and robust financial performance in 2025, driven by high R&D investment and strategic policy support [1][2][27]. Financial Performance - In the first half of 2025, the company reported a record revenue of approximately HKD 61.1 billion, with net profit around HKD 11.7 billion [1]. - R&D investment reached about HKD 10.2 billion, leading to 38 major R&D milestones, including 16 innovative products [1]. Innovation and Product Development - The company’s Yttrium-90 microsphere injection received FDA approval for primary liver cancer, achieving a 98.5% objective response rate [2][7]. - The company has successfully integrated multiple innovative products into the commercial insurance directory, enhancing its market presence [2][3]. - The nuclear medicine segment has become a core revenue driver, with approximately HKD 4.2 billion in revenue, reflecting over 100% growth [4]. Market Potential and Strategy - The global liver cancer treatment market is projected to reach USD 9.81 billion by 2030, indicating significant growth potential for the company's innovative therapies [6]. - The company is positioned to leverage its comprehensive clinical and commercialization network across Europe, the US, and Japan to enhance product penetration [2][9]. Regulatory and Policy Support - Recent policy measures from the National Healthcare Security Administration have established a stable pricing mechanism for innovative drugs, further empowering the company's growth [1][27]. - The establishment of a zero-radiation smart nuclear medicine factory in Chengdu represents a strategic investment in advanced manufacturing capabilities [15][16]. Competitive Landscape - The company is one of only four globally to commercialize innovative nuclear medicines, positioning it as a leader in the field [3][9]. - The market for radiopharmaceuticals is rapidly expanding, with significant transactions involving major multinational corporations [9][10]. Product Pipeline and Future Outlook - The company has a robust pipeline with 15 innovative products targeting various cancers, including prostate and kidney cancers, with several in Phase III clinical trials [10][12]. - The innovative eye drug OC-01 for dry eye syndrome has shown promising clinical results and is expected to capture a significant market share in China [25][26]. Investment Sentiment - The company's strategic value has been recognized by the capital market, with multiple institutions raising their ratings and target prices significantly [27].

Investment Rating - The report assigns a "Buy" rating for the company with a target price of 13.07 HKD, based on a 20x PE for 2025 [5]. Core Insights - The company is positioned for accelerated growth through a dual strategy of "independent research and global expansion," which enhances its international transformation potential [1][12]. - In 2024, the company achieved a revenue of 10.784 billion RMB, a year-on-year increase of 10.59%, and a net profit of 2.286 billion RMB, up 31.28% year-on-year, driven by increased demand for core products in nuclear medicine and cardiovascular precision intervention [21]. Summary by Sections 1. Company Overview - Founded in 1939, the company operates across three main sectors: nuclear medicine for tumor diagnosis and treatment, cardiovascular precision intervention, and pharmaceutical technology [1][12]. - The company has over 10,000 employees globally and more than 30 subsidiaries, with a diverse product portfolio exceeding 200 items in the medical insurance directory [1][12]. 2. Pharmaceutical Technology - The company is focused on developing innovative drugs in respiratory and critical care, with STC3141 showing promise as a new treatment for sepsis [2][31]. - The global market for sepsis treatment is projected to grow from 12.54 billion USD in 2024 to 19.37 billion USD by 2032, indicating significant unmet clinical needs [40]. 3. Nuclear Medicine - The company has established a complete industrial chain in nuclear medicine, with its core product, Yttrium-90 microsphere injection, rapidly gaining market traction since its approval in 2022 [3][4]. - The company is advancing multiple nuclear medicine products through clinical trials, including TLX591 for prostate cancer and GPN02006 for liver cancer diagnosis, positioning itself in the global first-tier of development [4][12]. 4. Financial Forecast - Revenue projections for 2025-2027 are 12.405 billion RMB, 13.729 billion RMB, and 15.113 billion RMB, respectively, with net profits expected to be 2.121 billion RMB, 2.396 billion RMB, and 2.773 billion RMB [5].

Group 1 - Nanshan Aluminum International (02610.HK) expects a mid-term net profit of approximately $225 million to $265 million for the six months ending June 30, 2025, compared to a net profit of about $159 million for the same period ending June 30, 2024 [1] - The increase in net profit is primarily attributed to an improvement in gross margin, driven by higher alumina prices and relatively stable unit production costs [1] - The average selling price of the company's products for the first half of 2025 is expected to be around $530 per ton, up from approximately $387 per ton in the first half of 2024, but lower than $561 per ton in the second half of 2024 [1] Group 2 - TCL Electronics (01070.HK) anticipates a year-on-year adjusted net profit growth of approximately 45% to 65% for the first half of 2025 [2] - Renrui Talent (06919.HK) expects a mid-term profit attributable to equity holders to increase by 66.7% to 94.1% [2] - China Rare Earth Holdings (03788.HK) reports an increase in total gold resources to 5.07 million ounces [2]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對 其準確性或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內 容而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 加入國際多中心 III 期臨床試驗的申請已獲中國藥監局默示許可 本公告乃遠大醫藥集團有限公司(「本公司」，連同其附屬公司統稱「本集團」)之董事 會(「董事會」)自願刊發。 董事會欣然公告，本集團用於治療前列腺癌的全球創新在研放射性核素偶聯藥物 「( RDC」) TLX591 (177Lu-rosopatamab tetraxetan)加入國際多中心 III 期臨床試驗的申請， 近日已獲得中華人民共和國國家藥品監督管理局(「中國藥監局」)默示許可，這是本集 團在核藥抗腫瘤診療領域的重要研發進展。本集團高度重視核藥產業全球化發展戰略， 積極推進創新核藥產品的全球化開發及註冊進程，並將持續深化本集團核藥產品管線的 全球化拓展。 該研究是一項前瞻性、隨機、對照、開放標籤、國際多中心的 III 期臨床試驗，擬在中 國、美國、澳大利亞、新西蘭及歐洲等全球多個國家和地區入組 500 余名患者，旨在評 估 TLX591 ...

Grand Pharmaceutical Group Limited 遠大醫藥集團有限公司* 香港交易及結算所有限公司及香港聯合交易所有限公司對本公告之內容概不負責，對 其準確性或完整性亦不發表任何聲明，並明確表示概不就因本公告全部或任何部分內 容而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 本集團全球創新放射性產品 SIR-Spheres®釔[ 90Y]微球注射液 提前正式獲得 FDA 批准新增適應症 本公告乃遠大醫藥集團有限公司(「本公司」，連同其附屬公司統稱「本集團」)之董事 會(「董事會」)自願刊發。 ( 於百慕達註冊成立之有限公司 ) (股份代號：00512) 自願性公告 SIR-Spheres®釔[ 90Y]微球注射液，是一款針對肝臟惡性腫瘤的選擇性內放射治療產品， 採用全球領先的介入技術將釔[ 90Y]樹脂微球注入肝臟腫瘤血管，釋放高能量 β 放射線 殺滅腫瘤細胞，兼具了放射性藥物和精准介入治療的雙重優勢。本次新適應症的獲批是 基於一項前瞻性、多中心、開放標籤的臨床試驗（「DOORwaY90」）的中期結果。該 試驗中期數據顯示，DOORwaY90 成功達到預先設定的共同主要終點：經獨立中 ...

Core Insights - Telix Pharmaceuticals Limited is hosting an Investor Day on June 11, 2025, in New York City, focusing on growth opportunities in precision medicine and therapeutic radiopharmaceuticals [1][4] Company Overview - Telix is a biopharmaceutical company dedicated to developing and commercializing therapeutic and diagnostic radiopharmaceuticals, headquartered in Melbourne, Australia, with operations in the U.S., Brazil, Canada, Europe, and Japan [4] - The company is addressing significant unmet medical needs in oncology and rare diseases through its clinical and commercial stage products [4] Event Details - The Investor Day will feature key opinion leaders discussing the clinical utility and opportunities for Telix's theranostic candidates [2] - In-person attendance is available for institutional investors and analysts, with advance registration required [3] Key Opinion Leaders - Dr. Oliver Sartor, an expert in prostate cancer, will discuss TLX591, having published over 500 peer-reviewed articles and led pivotal Phase 3 studies [7] - Dr. John de Groot, a neuro-oncology expert, will present on TLX101, with over 200 peer-reviewed publications and significant involvement in clinical studies [7] - Dr. Joseph Osborne, specializing in renal cancer imaging, will cover TLX250-CDx, focusing on advancing molecular imaging [7]

Core Viewpoint - The recent advancements in innovative nuclear medicine products by the company, particularly the Yttrium-90 microsphere injection, have garnered significant international recognition, showcasing the clinical potential of its nuclear medicine pipeline [1][4][9]. Group 1: Product Developments - The innovative nuclear medicine product, Yttrium-90 microsphere injection, has been highlighted at major international conferences, indicating its clinical value and potential in treating liver cancer [4][5]. - The company has successfully launched a global innovative ophthalmic drug for treating demodex blepharitis, which is expected to enhance its market presence in the Greater Bay Area and mainland China [3][9]. - The Yttrium-90 microsphere injection has achieved a disease control rate of 90.9% and an objective response rate of 87.8% in clinical studies, establishing it as a leading treatment for hepatocellular carcinoma (HCC) [7][8]. Group 2: Financial Performance - The company's stock price has surged over 50% since early May, reaching a historical high of 9.19 HKD, with a year-to-date increase of over 130% [3]. - The Yttrium-90 microsphere injection has treated nearly 2,000 patients and is projected to generate approximately 500 million HKD in sales revenue for 2024, reflecting a year-on-year growth rate exceeding 140% [7][8]. Group 3: Research and Clinical Impact - The Yttrium-90 microsphere injection has become a focal point in global HCC treatment, with multiple studies presented at the ASCO and APPLE conferences [5][6]. - The company has trained over 1,100 doctors across 70 hospitals to enhance the clinical application of its products, indicating a commitment to improving treatment accessibility [8][9]. Group 4: Infrastructure and Future Plans - The company is establishing a "zero-radiation" intelligent nuclear medicine factory in Chengdu, which will serve as a comprehensive platform for research, production, and sales, enhancing its operational capabilities [13][16]. - The factory is set to be the first of its kind globally, with a planned investment exceeding 3 billion RMB, focusing on isotope production and automated manufacturing processes [16][18].

Core Viewpoint - The recent diagnosis of prostate cancer in former U.S. President Biden has highlighted the importance of early cancer screening, which aligns with the comprehensive strategies of Yuan Da Pharmaceutical in the prostate cancer sector [1][3]. Company Overview - Yuan Da Pharmaceutical has established a robust presence in the prostate cancer market with innovative medical devices and a comprehensive product portfolio that integrates diagnosis and treatment [1][2]. - The company has seen a significant stock price increase, reaching a nearly ten-year high of 9 HKD per share, with a cumulative rise of approximately 50% over the past two weeks [1]. Market Dynamics - The global prostate cancer treatment market is projected to grow from 13.5 billion USD in 2025 to 29.9 billion USD by 2034, with a CAGR of 9.2% [7]. - In China, the prostate cancer medication market was valued at approximately 30.3 billion CNY in 2023, reflecting a year-on-year growth of 15.07% [7]. Early Screening Importance - The early detection rate of prostate cancer in China is only 32%, significantly lower than the 92% in the U.S., leading to a higher incidence of late-stage diagnoses [9]. - Early-stage prostate cancer patients have a survival rate of up to 100%, while those with metastatic disease have only a 31% five-year survival rate [3]. Product Development and Clinical Trials - Yuan Da Pharmaceutical's innovative products include TLX591-CDx, which has completed patient enrollment for its Phase III clinical trial in China and is expected to submit for market approval within the year [2][10]. - The company has a pipeline of 15 innovative products in the nuclear medicine sector, covering multiple cancer types, and has achieved significant clinical milestones [16][17]. Strategic Positioning - The establishment of a global nuclear medicine R&D and production base in Chengdu, set to commence operations in June 2025, will enhance Yuan Da's capabilities in the nuclear medicine field [19]. - The company aims to create a comprehensive ecosystem for urogenital system diseases, integrating early screening and treatment solutions [15][20]. Future Outlook - Yuan Da Pharmaceutical is positioned to become a key player in the global pharmaceutical market, with a focus on innovation and expanding its market share in cancer diagnostics and treatment [20].