Core Insights - The company JieTai Technology announced that its AI-driven small molecule formulation optimization platform AiTEM has successfully achieved the primary endpoint of Phase III clinical trials for the candidate drug MTS-004, making it the first AI-enabled formulation new drug to complete Phase III trials in China [1][2] - MTS-004 is the first and currently the only drug in China to complete Phase III clinical trials for Pseudobulbar Affect (PBA), addressing a significant gap in the domestic treatment landscape for PBA [1][3] Company Overview - MTS-004 is a novel oral treatment candidate for PBA, designed as an orally disintegrating tablet (ODT) that dissolves quickly in the mouth without the need for water, improving patient experience and adherence to treatment [1][2] - The AiTEM platform utilizes JieTai's proprietary AI nano-delivery platform NanoForge, employing specialized algorithms for drug formulation design and optimization, significantly reducing the preclinical formulation optimization cycle from the industry average of 1-2 years to just 3 months [2] Clinical Trial Details - The Phase III clinical trial was led by Dr. Fan Dongsheng, a renowned expert in neurodegenerative diseases, and involved a double-blind, randomized, placebo-controlled multi-center study assessing the efficacy and safety of MTS-004 in PBA patients secondary to various neurological conditions [2] - A total of 264 participants were enrolled over a period of 9.5 months, with the trial conducted across 48 clinical centers, including prestigious hospitals such as Peking University Third Hospital and Xuanwu Hospital [2] Efficacy and Safety - MTS-004 demonstrated good overall safety and clear efficacy in treating PBA secondary to neurological diseases, significantly reducing the average frequency of PBA episodes after 12 weeks of treatment, with statistically significant differences observed [3] - The treatment effects were noted as early as the second week, with improvements in emotional control and quality of life measured by various scales, including CNS-LS scores and SF-36 mental health index [3] Future Plans - The company plans to submit a New Drug Application (NDA) to the National Medical Products Administration (NMPA) for MTS-004 for PBA indications in 2026, with intentions to explore potential expansion into swallowing disorder treatments post-approval [3]

Group 1 - Huawei is set to launch the Mate 70 Air, which supports 66W wired charging and will be available in three colors:曜金黑, 羽衣白, and 金丝银锦 [2] - Wang Ziru has officially joined Thunderbird Innovation, indicating a significant addition to the team [3] - Baidu's executive restructuring has seen Vice President Xie Guangjun take over the newly established business efficiency department [4] Group 2 - The iPhone Air has officially launched in China, but it only supports eSIM activation through offline verification at carrier stores [6] - Microsoft CEO Satya Nadella's total compensation for 2025 is reported to be $96.5 million, including $84.2 million in stock awards [6] - OpenAI has released a new AI-driven web browser called ChatGPT Atlas, which will compete directly with Google's Chrome [6] Group 3 - Sony has announced the release of the PlayStation 5 Pro in mainland China, with a suggested retail price of 5,599 yuan [6] - Former Vivo product manager Song Ziwei is venturing into AI hardware with a focus on AI makeup mirrors [6] - Wang Teng has stepped down from his position at Xiaomi's Zhengzhou branch, with Cheng Guang taking over [7] Group 4 - Anker has initiated a recall in Japan for four battery products due to production defects that could lead to internal short circuits [7] - The new Apple Vision Pro headset, priced from 29,999 yuan, is now assembled in Vietnam, marking a shift from its initial production in China [7] - Recent monitoring indicates that the price of 92-octane gasoline may drop to around 6 yuan per liter, marking a four-year low [9] Group 5 - AI-generated images of extreme poverty and child survivors of violence are increasingly being used by global health NGOs, raising concerns among health experts [10]

10月22日，近日，有多位网友发现喜茶不久前刚回归的人气产品"雪域·牦牛乳恰安莫"，在上架10日后陆续出现售罄情况，北京、天津、青岛、济南、西 安、沈阳、上海等城市不少门店内均已显示临时下架。对于上述情况，喜茶官方表示：原料牦牛乳冬季产量变化，近期可能会有短暂售罄的情况，目前正 在积极补货中。 据悉，"雪域·牦牛乳恰安莫"于2024年9月首次在西藏地区门店上线，受到广泛关注。今年5月、10月，"雪域·牦牛乳恰安莫"先后两次回归全国热销。公开 信息显示，牦牛乳作为该款产品原料，必须先经过风味测试，再通过各项严格的品质指标检测，喜茶还需要前往奶源产地和生产工厂进行实地考察及审 查，确保奶源品质符合喜茶要求。 责任编辑：宋雅芳 ...

Core Insights - Leju Robotics has completed nearly 1.5 billion yuan in Pre-IPO financing, with investments from multiple firms including Shenzhen Longhua Capital and Dongfang Precision [1] Financing Details - The financing round aims to enhance core technology research and development, deepen industry chain layout, and improve application scenarios for humanoid robots [1] - The funds will support the transition of humanoid robots towards large-scale production and diversified applications [1] Industry Chain Investments - Leju Robotics has invested in several upstream and downstream companies, including: - Quanzhibo (integrated joints) - Lijudongli (motors) - Lingxinqiaoshou (dexterous hands) - Kehang Shikong (data platform) - Jubrain Panshi (embodied brain) - Jushi Intelligent (operating system) [1] Collaborative Ventures - The company has partnered with Dongfang Precision to establish a large-scale humanoid robot production line [1] - Joint ventures include a humanoid robot controller company with Heertai and Dongfang Precision, and a production logistics solution company with Haichen [1]

据悉，此次合作的核心，在于将国家级环境风洞实验室深度融入超高速电摩的研发体系。清华合肥院风 洞是全球唯一具备多灾耦合模拟能力的公共安全科研设施，可模拟最高80m/s风速（相当于18级台风） 的极端气流环境，同时复现极寒、暴雪、冰冻、酷热、湿热、强日照等多种复杂气候条件，具备领先的 空气动力学综合验证能力。 首驱科技将依托清华合肥院的环境风洞与科研能力，建立行业首个系统性空气动力学研发流程，涵盖高 速工况下的整车风阻优化、多气候环境下的气动稳定性验证、以及基于CFD仿真与实测数据闭环的迭代 开发机制，推动国内超高速电摩的研发从依赖"路试+经验调校"的粗放模式，转向"仿真-测试-反馈-优 化"的科学化、数据化路径。（文猛） 责任编辑：宋雅芳 新浪科技讯 10月22日上午消息，首驱科技与清华大学合肥公共安全研究院（简称"清华合肥院"）签署 超高速电摩风洞实验战略合作协议，宣布全面进军超高速电摩赛道，致力于打造世界最快的两轮电动 车。 长期以来，两轮电动车市场以城市通勤为核心场景，研发逻辑围绕续航、成本与智能化展开，技术路径 趋于同质化。相比之下，国际超高速电摩赛事早已成为尖端电驱、能量管理与系统集成技术的前沿试验 ...

新浪科技讯 10月22日上午消息，近日，磁编码器企业北京金钢科技有限公司（以下简称"金钢科技"或 公司）宣布完成数千万元Pre-A++轮融资，投资方为盈富泰克。此前，公司于上半年完成中科创星投资 的Pre-A轮及顺融资本、江阴人才投资的Pre-A+轮。半年内连续完成Pre-A系列三轮融资，累计融资金额 共计近亿元。资金将主要用于技术迭代、新产品研发与市场推广。 责任编辑：宋雅芳 金钢科技成立于2017年，专注于磁编码器市场已将近十年，已经成长为全球机器人核心零部件领域的标 杆企业。作为国内最早专注于机器人领域的编码器企业，目前金钢科技在国内人形机器人编码器市场的 市占率达到80%，是众多头部机器人本体、关节厂家的核心供应商。 ...

【#微软CEO年薪近1亿美元#】当地时间10月21日，美国证交会（SEC）文件显示，微软董事长兼首席 执行官萨提亚·纳德拉（Satya Nadella）2025年的总薪酬为9650万美元，其中包括8420万美元的股票奖 励。（智通财经） ...

Core Insights - The tactical shooting game "Delta Operation" has recently faced significant backlash from players due to official adjustments to a popular player-created mode called "Shared Prison" and rampant cheating issues [2][3][4] Player Feedback and Official Response - The game attracted a large player base with its high-risk "Search, Fight, Evacuate" gameplay, leading to the organic development of the "Shared Prison" strategy among players [3] - Following the official announcement to modify the game mechanics, over 560,000 comments criticizing the changes flooded the official channels, indicating strong player discontent [4][6] - The official apology acknowledged the confusion and dissatisfaction caused by the updates, admitting that the handling of the situation was abrupt and inappropriate [6] Impact on Game Performance - The game's iOS revenue saw a significant decline, with daily earnings dropping from approximately $4.59 million to a low of $1.51 million, marking a decrease of over 67% [9][19] - The game's ranking on the iOS free chart fell from a peak of 6th to around 26th, reflecting a loss of player engagement and trust [9][22] Cheating Issues - The game has been plagued by a proliferation of cheats, with numerous shops selling "Delta Assist" and "Delta Vision" hacks on second-hand trading platforms [10][12] - Some shops reportedly achieve monthly sales exceeding 6,000 units, leading to substantial income from these illicit products [12] - The official response to cheating has included significant bans, with over 88,000 accounts banned in a week, highlighting the severity of the cheating problem [16][19] Competitive Landscape - The market environment for "Delta Operation" has become increasingly competitive, with new entrants like NetEase's "Firefly Assault" capitalizing on the game's controversies to attract users [22] - Competitors are actively marketing similar gameplay experiences, which could lead to a further decline in "Delta Operation's" user base if dissatisfaction continues [22]

Core Viewpoint - Netflix reported its Q3 2025 financial results, showing revenue growth but falling short of analyst expectations, leading to a significant drop in stock price after the announcement [2][3]. Financial Performance - Q3 revenue reached $11.51 billion, a 17.2% increase from $9.83 billion in the same quarter last year, but slightly below analyst expectations of $11.52 billion [4]. - Net profit for Q3 was $2.547 billion, up 8% from $2.364 billion year-over-year [4]. - Earnings per share (EPS) were $5.87, an increase from $5.40 in the previous year, but below the expected $6.94 [4]. Regional Revenue Breakdown - Revenue from the U.S. and Canada was $5.072 billion, up 17% from $4.322 billion [4]. - Revenue from Europe, the Middle East, and Africa was $3.699 billion, an 18% increase from $3.133 billion [4]. - Latin America revenue reached $1.371 billion, a 10% increase from $1.241 billion [4]. - Asia-Pacific revenue was $1.369 billion, up 21% from $1.128 billion [4]. Operational Metrics - Q3 operating profit was $3.248 billion, up from $2.909 billion year-over-year, with an operating margin of 28.2%, down from 29.6% [5]. - Net cash from operating activities was $2.825 billion, an increase from $2.331 billion [5]. - Free cash flow for Q3 was $2.660 billion, up from $2.194 billion [5]. Stock Buyback and Debt - Netflix repurchased 1.5 million shares for a total of $1.9 billion, with an additional $10.1 billion available for future buybacks [6]. - Total debt stood at $14.5 billion, with cash and cash equivalents of $9.3 billion [6]. Future Outlook - For Q4 2025, Netflix expects revenue of $11.96 billion, a 16.7% year-over-year increase, and operating profit of $2.860 billion [7]. - The company projects full-year revenue of $45.1 billion for 2025, a 16% increase from 2024, with an operating margin of 29% [7]. Stock Price Movement - Following the earnings report, Netflix's stock price fell over 6% in after-hours trading, closing at $1,162.96, down $78.39 [3][8]. - The stock had previously closed at $1,241.35, reflecting a 0.23% increase during regular trading hours [8].

"提车一个月维修了7次，品质堪忧！" 东风日产N7定位中高级纯电轿车，面向主流家庭用户，这个价格初看确实十分有竞争力。东风汽车有限公司执行副总裁、东风日产副总经 理周锋更是宣称， "东风日产以打造20万内'最家'纯电轿车为目标，在三个关键领域做到了领先：坚守合资品质高标准、智能化进入行业第 一梯队、舒适超越豪华车。 " 不过，从用户们的反馈来看，他提到的"坚守合资品质高标准"要被打脸了。近期，多位车主在黑猫投诉以及社交媒体上反馈，他们购车没多 久就遇到了车机黑屏死机、车辆异响、动力电池系统故障等问题。 一位用户投诉称，他于9月16日提车东风日产N7 625 Max版本，9月20日早上用车时就发现显示电池动力系统故障，无法启动车辆，报售后 后工作人员态度敷衍，让自己报保险拖车到店检测。检测结果显示"电芯电压传感器故障""电池温度传感器严重故障""均衡回路温度无效故 障"等问题，他要求予以退换货，但4S回复称不符合三包退换货条件，只能维修拆开电池包更换零部件。 "才提车几天、行驶不到100km，就发生电池质量问题，我完全有理由怀疑这是一台存在先天问题的故障车！谁知道后续会不会导致出现安 全问题。 "他吐槽称。 一 ...