Company Overview - Rongchang Biopharmaceuticals is an innovative biopharmaceutical company focused on antibody-drug conjugates (ADC), antibody fusion proteins, monoclonal antibodies, and bispecific antibodies [2] - The company aims to discover, develop, and commercialize innovative and distinctive first-in-class and best-in-class biopharmaceuticals to address unmet clinical needs in autoimmune diseases, oncology, and ophthalmology [2] - Main business revenue composition includes 99.46% from product sales, 0.38% from material sales, and 0.16% from leasing services [2] Financial Performance - As of June 30, 2025, Rongchang Biopharmaceuticals reported a revenue of 1.098 billion yuan, a year-on-year increase of 48.02% [3] - The net profit attributable to shareholders was -450 million yuan, reflecting a year-on-year growth of 42.40% [3] Shareholder and Market Activity - As of June 30, 2025, the number of shareholders increased to 12,900, up 90.69% from the previous period, while the average circulating shares per person decreased by 47.56% to 12,595 shares [3] - The stock price experienced a significant increase of 209.47% year-to-date, but has seen a decline of 6.07% in the last five trading days and 10.22% in the last 20 days [1] - Major shareholders include Hong Kong Central Clearing Limited as the second-largest shareholder with 9.3526 million shares, and several new institutional investors have entered the top ten shareholders list [4]

Core Insights - The report from Guojin Securities highlights the significant advancements in China's innovative drug research presented at the ESMO conference, indicating a potential boost for the international expansion of these drugs [1] Group 1: Innovative Drug Research - The number of significant research publications from Chinese pharmaceutical companies at ESMO has reached a historical high, making it a focal point of the conference [1] - A total of 35 Chinese studies were included in the regular oral abstracts for the 2025 ESMO conference, with 14 formal oral presentations, a significant increase from 5 in 2024 [1] - The inclusion of 23 Chinese studies in the Late-Breaking Abstracts (LBA) category also set a new record, showcasing the research strength and academic influence of Chinese companies on the international stage [1] Group 2: ADC Developments - Domestic ADCs are demonstrating the potential to redefine existing clinical treatment standards, with notable products like Kelun's SKB264 showing promising Phase III clinical data for NSCLC and HR+/HER2- breast cancer [2] - The mOS data for SKB264 in the second-line EGFRm NSCLC treatment is particularly impressive, with a hazard ratio of 0.60, indicating a significant survival benefit [2] - Bai Li Tian Heng's ADC, iza-bren, has achieved breakthroughs in treating nasopharyngeal carcinoma, marking a critical milestone from concept validation to efficacy verification [2] Group 3: Bispecific and Multi-specific Antibodies - Bispecific and multi-specific antibodies are poised to upgrade existing immunotherapy and targeted therapy, with significant data from Kangfang Biotech's PD-1/VEGF bispecific antibody showing superior results compared to traditional treatments for advanced squamous NSCLC [3] - The mPFS for the combination of the bispecific antibody and chemotherapy was reported at 11.14 months versus 6.90 months for the comparator, with a hazard ratio of 0.60, indicating a strong potential to reshape first-line treatment standards [3] - The HER2 bispecific antibody KN026 from Shiyao Group/Kangning Jierei has shown promising results in III phase trials for gastric cancer, indicating its potential as a global leader in this category [3]

Core Viewpoint - Recent clinical trial results for Taitasip from Rongchang Biologics have met primary and all secondary endpoints, indicating strong potential for the drug in the market [1] Group 1: Clinical Results - Rongchang Biologics announced that Taitasip's Phase III results in mainland China have achieved all major and secondary endpoints [1] - The positive clinical data supports a favorable outlook for the sales prospects of both Taitasip and Vidisimo [1] Group 2: Market Potential - The global sales peak for Rongchang Biologics is projected to exceed $2.5 billion, reflecting the significant market value of Taitasip in the autoimmune sector [1] - The company is expected to gradually realize this market value in its overall valuation [1] Group 3: Financial Projections - Revenue forecasts for 2025 to 2027 have been raised by 1% to 4% based on the promising clinical data [1] - The target price for Rongchang Biologics has been increased to HKD 109, maintaining a "Buy" rating [1]

Group 1 - Rongchang Biologics (09995.HK) experienced a nearly 5% increase in stock price, reaching a rise of 4.81% at HKD 96.95 [1] - The trading volume for Rongchang Biologics was reported at HKD 706 million [1]

Core Viewpoint - Rongchang Biopharma (09995) shares increased by nearly 5%, closing at HKD 96.95 with a trading volume of HKD 706 million, driven by significant research presentations at the ESMO annual meeting in Berlin [1] Group 1: Research Highlights - Rongchang Biopharma presented 10 key studies at the ESMO annual meeting from October 17 to 21, 2025, including the pivotal Phase III study data of Vidisicimab for first-line treatment of urothelial carcinoma, which was prominently featured at the conference and published in the New England Journal of Medicine [1] - The Phase III clinical research data for Taitasip in treating IgA nephropathy will be presented as a "Late-Breaking Oral" report at the American Society of Nephrology (ASN) annual meeting scheduled for November 5 to 9, 2025, in Houston, USA [1] Group 2: Market Outlook - Huatai Securities believes that the dense data readouts validate the global competitiveness of the company's pipeline and are expected to accelerate its overseas expansion: 1) The overseas Phase I/II study of Vidisicimab is progressing steadily, with expectations for the 2LUC indication to achieve BLA by early 2026; 2) RC148 has received CDEBTD approval, and the overseas Phase I/II clinical trial has been approved by the FDA, indicating significant overseas potential; 3) The global Phase III enrollment for Taitasip is proceeding smoothly, with pSS expected to become the next key indication [1]

Core Viewpoint - Rongchang Biopharma (09995) experienced a nearly 5% increase in stock price, reaching HKD 96.95, with a trading volume of HKD 706 million, following the announcement of significant research findings at the 2025 European Society for Medical Oncology (ESMO) annual meeting in Berlin [1] Group 1: Research Highlights - Rongchang Biopharma presented 10 major studies at the ESMO annual meeting, including the Phase III study data of Vidisicimab for first-line treatment of urothelial carcinoma, which was prominently featured at the conference and published in the New England Journal of Medicine (NEJM) [1] - The Phase III clinical research data for Taitasip in treating IgA nephropathy will be presented as a "Late-Breaking Oral" report at the upcoming 2025 American Society of Nephrology (ASN) annual meeting in Houston, scheduled for November 5-9 [1] Group 2: Market Outlook - Huatai Securities believes that the dense data readouts demonstrate the global competitiveness of the company's pipeline and are expected to accelerate its overseas expansion: 1) The overseas Phase I/II study of Vidisicimab is progressing steadily, with expectations for the 2LUC indication to achieve BLA by early 2026 [1] - RC148 has received CDEBTD approval, and the overseas Phase I/II clinical trial has been approved by the FDA, indicating significant potential for international market entry [1] - The global Phase III enrollment for Taitasip is proceeding smoothly, with primary Sjögren's syndrome (pSS) expected to become a key indication [1]

Core Viewpoint - Rongchang Biopharmaceuticals has shown significant stock performance with a year-to-date increase of 220.29%, indicating strong market interest and potential growth in the biopharmaceutical sector [1][3]. Financial Performance - As of June 30, 2025, Rongchang Biopharmaceuticals reported a revenue of 1.098 billion yuan, representing a year-on-year growth of 48.02% [3]. - The company recorded a net profit attributable to shareholders of -450 million yuan, which is a 42.40% increase compared to the previous period [3]. Stock Market Activity - On October 21, 2023, the stock price of Rongchang Biopharmaceuticals reached 96.44 yuan per share, with a trading volume of 351 million yuan and a turnover rate of 2.28% [1]. - The stock has experienced a net outflow of 28.82 million yuan from major funds, with significant buying and selling activity from large orders [1]. Shareholder Structure - As of June 30, 2025, the number of shareholders increased to 12,900, a rise of 90.69% from the previous period [3]. - New significant shareholders include Hong Kong Central Clearing Limited and several mutual funds, indicating growing institutional interest [4]. Business Overview - Rongchang Biopharmaceuticals focuses on innovative biopharmaceuticals, particularly in the fields of antibody-drug conjugates (ADC), monoclonal antibodies, and bispecific antibodies [2]. - The company aims to address unmet clinical needs in autoimmune diseases, oncology, and ophthalmology, with a revenue composition of 99.46% from product sales [2].

Group 1 - Yongtai Biologics-B (06978.HK) increased by 14.94% [1] - Hepp Pharmaceuticals-B (02142.HK) rose by 5.32% [1] - Rongchang Biologics (09995.HK) gained 5.14% [1] - Yaojie Ankang (02617.HK) saw an increase of 5.02% [1] - Cornerstone Pharmaceuticals-B (02616.HK) experienced a rise of 3.92% [1]

格隆汇10月17日丨荣昌生物(09995.HK)公告，公司将于2025年10月30日(星期四)举行董事会会议，藉以 (其中包括)考虑及批准公司及其附属公司截至2025年9月30日止9个月未经审计第三季度业绩及其刊发。 ...

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性 或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容而產生或因倚 賴該等內容而引致的任何損失承擔任何責任。 RemeGen Co., Ltd.* 榮 昌 生 物 製 藥（ 煙 台 ）股 份 有 限 公 司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：9995） 董事會召開日期 榮昌生物製藥（煙台）股份有限公司（「本公司」）之董事會（「董事會」）謹此宣佈， 本公司將於2025年10月30日（星期四）舉行董事會會議，藉以（其中包括）考慮及 批准本公司及其附屬公司截至2025年9月30日止九個月之未經審計第三季度業績 及其刊發。 承董事會命 榮昌生物製藥（煙台）股份有限公司 董事長兼執行董事 王威東先生 中華人民共和國，煙台 2025年10月17日 於本公告日期，董事會成員包括執行董事王威東先生、房健民博士、林健先生及 溫慶凱先生；非執行董事王荔強博士及蘇曉迪博士；及獨立非執行董事郝先經先 生、陳雲金先生及黃國濱先生。 * 僅供識別 ...