上海复星医药（集团）股份有限公司 证券代码：600196 股票简称：复星医药 编号：临 2026-014 关于控股子公司药品获临床试验批准的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或 者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 一、概况 近日，上海复星医药（集团）股份有限公司（以下简称"本公司"）控股子公 司上海复宏汉霖生物技术股份有限公司及其控股子公司（以下合称"复宏汉霖"） 收到国家药品监督管理局（以下简称"国家药监局"）关于同意注射用 HLX43（即 靶向 PD-L1 抗体偶联药物，申请注册分类：治疗用生物制品 1 类）联合 HLX07（即 重组抗 EGFR 人源化单克隆抗体注射液，申请注册分类：治疗用生物制品 1 类）及斯 鲁利单抗注射液（中国境内 1商品名：汉斯状®）用于晚期实体瘤治疗（以下简称"该 治疗方案"）开展临床试验的批准。复宏汉霖拟于条件具备后在中国境内开展该治 疗方案的Ⅱ期临床研究。 二、所涉药品的基本信息及研究情况 本次治疗方案中所涉 HLX43 为复宏汉霖利用许可引进的新型 DNA 拓扑异构酶 I 抑制剂小分子毒素-肽链连接子与其自主 ...

证券代码：600196 股票简称：复星医药 编号：临 2026-012 上海复星医药（集团）股份有限公司 第十届董事会第二十三次会议（临时会议）决议公告 上海复星医药（集团）股份有限公司 董事会 二零二六年一月二十七日 1 上海复星医药（集团）股份有限公司（以下简称"本公司"）第十届董事会 第二十三次会议（临时会议）于2026年1月26日召开，全体董事以通讯方式出席 了会议，本次会议的召开符合《中华人民共和国公司法》（以下简称"《公司法》"）、 其他有关法律法规和《上海复星医药（集团）股份有限公司章程》（以下简称"《公 司章程》"）的规定。会议审议并达成如下决议： 审议通过关于聘任高级管理人员的议案。 经首席执行官提名，同意聘任孟凌媛女士为本公司副总裁，任期自 2026 年 1 月 26 日起至本届董事会任期届满之日止。 表决结果：同意 12 票，反对 0 票，弃权 0 票。 本议案在董事会审议前，已经董事会提名委员会审核通过。 新任高级管理人员的简历详见附件。 特此公告。 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性 陈述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 附件 ...

复星医药公告称，2026年1月26日，公司第十届董事会第二十三次会议审议通过聘任高级管理人员的议 案。经首席执行官提名，同意聘任孟凌媛女士为公司副总裁，任期自当日起至本届董事会任期届满之日 止。表决结果为同意12票，反对0票，弃权0票。孟凌媛1978年1月出生，加入公司前，有丰富的审计及 管理经验，截至26日，其未持有公司股份，与公司相关人员无关联关系，无不得担任高管的情形。 ...

复星医药公告称，其控股子公司复宏汉霖收到国家药监局关于同意注射用HLX43联合HLX07及斯鲁利 单抗注射液用于晚期实体瘤治疗开展临床试验的批准，拟于条件具备后在中国境内开展Ⅱ期临床研究。 截至2025年12月，该治疗方案累计研发投入约266万元。目前全球范围内尚无同类联合用药治疗方案获 批上市。所涉在研药品尚处临床试验阶段，药品研发存在风险。 ...

Core Viewpoint - The vaccine sector is experiencing strong performance due to the emergence of Nipah virus cases in India, leading to increased investment in related biopharmaceutical ETFs [1][3]. Group 1: Market Performance - The biopharmaceutical ETF Huatai (159839) saw a significant increase of 2.13% with a trading volume exceeding 60 million yuan, marking a 133% increase compared to the previous period [1]. - The ETF received a net subscription of 16.5 million shares today, accumulating nearly 40 million yuan in the last five days [1]. - Major component stocks of the ETF showed positive performance, with Zhifei Biological rising nearly 15%, Watson Bio increasing over 11%, and Hualan Biological up nearly 7% [3]. Group 2: Nipah Virus Impact - Five confirmed cases of Nipah virus infection have been reported in West Bengal, India, including healthcare workers, with nearly 100 individuals under home quarantine [3]. - The Nipah virus can attack the lungs and brain, with symptoms including fever, headache, drowsiness, and confusion, and a mortality rate of over 40% [3]. - There is currently no specific vaccine or effective treatment for the Nipah virus [3]. Group 3: Vaccine Development and Innovation - Hualan Biological received approval for clinical trials of its recombinant shingles vaccine, while Zhifei Biological's CA111 injection has entered Phase I clinical trials [7]. - The vaccine industry is focusing on technological upgrades and exploring new markets, particularly in the Middle East [8]. - The growth of the vaccine sector is expected to be driven by the increasing immunization needs of the aging population, shifting focus from children to a broader demographic [8]. Group 4: mRNA Vaccine Developments - Recent positive clinical data from mRNA vaccine leaders indicate a breakthrough development window for therapeutic cancer vaccines [9]. - mRNA technology offers significant advantages over traditional methods, including rapid production capabilities and enhanced safety profiles [9].

Core Viewpoint - Fosun Pharma disclosed a notice regarding the pledge and release of shares by its controlling shareholder, Shanghai Fosun High Technology (Group) Co., Ltd, indicating a pledge of 32 million shares for debt repayment purposes [1] Group 1: Share Pledge Details - Fosun High Technology pledged 32 million shares to Industrial and Commercial Bank of China, accounting for 3.33% of its total holdings and 1.20% of the company's total share capital [1][2] - The pledge period is from January 22, 2026, to January 26, 2028, with the purpose of repaying debts [1][2] Group 2: Share Release Details - Fosun High Technology released 102.65 million shares from pledge, which is 10.68% of its total holdings and 3.84% of the company's total share capital [3] - As of January 22, 2026, the remaining pledged shares amount to 476.28 million, representing 49.54% of Fosun High Technology's holdings and 17.84% of the company's total share capital [3][4] Group 3: Shareholding Structure - As of January 22, 2026, Fosun High Technology holds 961.42 million shares in total, which includes 889.89 million A-shares and 71.53 million H-shares, constituting approximately 36.00% of the company's total shares [3][4] - Together with its concerted actions, Fosun High Technology and its affiliates hold 967.81 million shares, representing 36.24% of the company's total shares [4]

Group 1 - The core point of the article is that Fosun Pharma announced the pledge and release of part of its A-share holdings by its controlling shareholder, Shanghai Fosun High Technology (Group) Co., Ltd. [1] - The number of shares pledged in this transaction is 32,000,000 shares [1]

Core Viewpoint - Fosun Pharma (02196) announced that its controlling shareholder, Fosun High Technology Group Co., Ltd., has pledged and released part of its A-share holdings in the company [1] Group 1 - The number of pledged shares is 32 million, which accounts for 3.33% of the shares held by the controlling shareholder and 1.20% of the total shares of the company [1] - The controlling shareholder released 103 million shares from pledge on January 22, 2026, leaving 476 million shares still pledged [1]

Core Viewpoint - Fosun Pharma announced a plan to spin off its subsidiary Fosun Antigen for a listing on the Hong Kong Stock Exchange, aiming to enhance financing channels and market competitiveness, despite the current downturn in the domestic vaccine industry and Fosun Antigen's poor financial performance [1][3]. Financial Performance - Fosun Antigen's revenue is projected to decline significantly from 461 million yuan in 2022 to 97.42 million yuan in 2024, with a net profit turning from a profit of 86.64 million yuan to a loss of 123.38 million yuan [3]. - The company's total assets as of December 31, 2024, are reported at 345.86 billion yuan, with a debt-to-asset ratio of 33.87% [3]. - The net cash flow from operating activities is negative at -105.29 million yuan for 2024, indicating financial strain [3]. Market Context - The domestic vaccine industry is currently facing challenges, with significant price competition among established products, leading to revenue declines for major players [6][9]. - The market for flu vaccines and rabies vaccines is particularly competitive, with price cuts from leading companies impacting overall sales [6][9]. Product Pipeline - Fosun Antigen has a limited product lineup, with four vaccines currently on the market, including rabies and flu vaccines, which are in a crowded market [5][6]. - The company is developing several vaccines, including the 13-valent and 24-valent pneumococcal conjugate vaccines, but lacks progress compared to competitors [7][10]. Competitive Landscape - The pneumococcal vaccine market is becoming increasingly competitive, with multiple players entering the space, leading to declining sales for existing products [9][12]. - Fosun Antigen's 24-valent pneumococcal vaccine is still in the early clinical trial phase, while competitors have advanced further in their development [10][12].

Core Viewpoint - Fosun Pharma (02196) announced that its controlling shareholder, Fosun High Technology Group Co., Ltd., has pledged and released part of its A-share holdings in the company [1] Group 1 - The number of pledged shares is 32 million, which accounts for 3.33% of the shares held by the controlling shareholder and 1.20% of the total shares of the company [1] - The controlling shareholder released 103 million shares from pledge on January 22, 2026, with 476 million shares remaining pledged [1]