证券代码：600867 证券简称：通化东宝 公告编号：2025-066 关于变更会计师事务所的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 拟聘任的会计师事务所名称：大信会计师事务所（特殊普通合伙）（以下 简称"大信会计师事务所"或"大信"）。 原聘任的会计师事务所名称：北京德皓国际会计师事务所（特殊普通合伙） （以下简称"北京德皓国际会计师事务所"） 通化东宝药业股份有限公司 变更会计师事务所的简要原因：根据《国有企业、上市公司选聘会计师事 务所管理办法》的相关规定，综合考虑通化东宝药业股份有限公司（以下简称"公 司"）业务发展和未来审计的需要，经公司审慎评估和研究，拟变更会计师事务所。 根据公司选聘会计师事务所的竞争性谈判结果，拟聘任大信会计师事务所为 2025 年度财务报告审计机构和内部控制审计机构。公司已就该事项与北京德皓国际会计 师事务所进行了充分沟通，其已知悉本次变更事项并对此无异议。 公司董事会审计委员会、董事会对本次变更会计师事务所事项均无异议。 本事项尚须提交公司股东会审议。 一、拟选 ...

证券代码：600867 证券简称：通化东宝 公告编号：2025-065 通化东宝药业股份有限公司 关于取消监事会并修订《公司章程》 及修订和新增部分治理制度的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 一、取消监事会的相关情况 根据《公司法》《关于新<公司法>配套制度规则实施相关过渡期安排》《上 市公司章程指引》等相关法律法规、规范性文件的规定，结合公司实际情况，公 司不再设置监事会与监事，由董事会审计委员会行使《公司法》规定的监事会的 职权。《监事会议事规则》等监事会相关制度相应废止，《公司章程》以及公司 各项治理制度中涉及监事会、监事的规定不再适用。 在公司股东会审议通过取消监事会事项前，公司监事会仍将严格按照法律法 规及规范性文件的要求继续履行职能，维护公司及全体股东的合法利益。 二、修订《公司章程》的相关情况 为进一步完善公司治理，公司根据《公司法》《上市公司章程指引》《上海 证券交易所股票上市规则》等法律法规、规范性文件的最新修订及更新情况，结 合公司实际情况，对《公司章程》的部分条款进行修订。 因本次修订 ...

证券代码：600867 证券简称：通化东宝 公告编号：2025-069 通化东宝药业股份有限公司 关于召开2025年第三次临时股东会的通知 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 一、 召开会议的基本情况 (一)股东会类型和届次 2025年第三次临时股东会 (二)股东会召集人：董事会 (三)投票方式：本次股东会所采用的表决方式是现场投票和网络投票相结合的方 式 (四)现场会议召开的日期、时间和地点 召开的日期时间：2025 年 11 月 3 日 10 点 00 分 召开地点：公司会议室 (五)网络投票的系统、起止日期和投票时间。 网络投票系统：上海证券交易所股东会网络投票系统 网络投票起止时间：自2025 年 11 月 3 日 至2025 年 11 月 3 日 1 股东会召开日期：2025年11月3日 本次股东会采用的网络投票系统：上海证券交易所股东会网络投票系统 采用上海证券交易所网络投票系统，通过交易系统投票平台的投票时间为股 东会召开当日的交易时间段，即 9:15-9:25,9:30-11:30， ...

本公司监事会及全体监事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 证券代码：600867 证券简称：通化东宝 公告编号：2025-064 通化东宝药业股份有限公司 第十一届监事会第十二次会议决议公告 内容详见公司于 2025 年 10 月 18 日在中国证券报、上海证券报及上海证券 交易所网站（www.sse.com.cn）披露的《通化东宝关于取消监事会并修订<公司 章程>及修订和新增部分治理制度的公告》。 表决结果：同意 3 票 反对 0 票 弃权 0 票 本议案尚需提交股东会审议。 一、监事会会议召开情况 通化东宝药业股份有限公司（以下简称"公司"或"通化东宝"）第十一届 监事会第十二次会议，于 2025 年 10 月 17 日在公司会议室以现场结合通讯方式 召开，会议通知于 2025 年 10 月 10 日，以书面、电子邮件等形式发出。本次会 议应参加会议监事 3 人，实际参加会议监事 3 人。会议由监事会主席王君业先生 主持。符合《公司法》和《公司章程》的规定，所作决议合法有效。 2025 年 10 月 18 日 二、监事会会议审议情况 ...

通化东宝公告，拟以2000万元-4000万元回购公司股份，回购价格不超过10元/股。本次回购股份将用于 员工持股计划及/或股权激励。预计回购股份数量不低于200万股且不超过400万股，回购期限为董事会 审议通过本次回购股份方案之日起6个月内。资金来源为公司自有资金。 ...

Meeting Overview - The first meeting of the 2025 Employee Stock Ownership Plan (ESOP) of Tonghua Dongbao Pharmaceutical Co., Ltd. was held on October 15, 2025, via communication methods, with 75 participants representing a total of 39.8541 million shares, accounting for 100% of the ESOP's total shares [2][3] Resolutions Passed - The meeting approved the establishment of the 2025 ESOP Management Committee to enhance the management efficiency of the ESOP and protect the rights of the shareholders [2][4] - The committee will consist of three members, with Zhang Guodong serving as the committee chair, and its term will align with the duration of the ESOP [4][5] Committee Authority - The meeting authorized the 2025 ESOP Management Committee to handle various matters related to the ESOP, including convening meetings, managing accounts, and overseeing share subscriptions [5][6] - The committee is also responsible for managing the distribution of rights, handling changes or terminations of the ESOP, and executing investment strategies as authorized by the shareholders [6][7]

Core Insights - The recombinant protein concept sector rose by 2.66%, ranking 7th among concept sectors, with 49 stocks increasing in value, including *ST Wanfang, which hit the daily limit, and notable gainers such as Saiseng Pharmaceutical, Kefu Medical, and Rejing Bio, which rose by 9.16%, 7.86%, and 6.96% respectively [1][2] Market Performance - The top-performing concept sectors today included Tonghuashun Fruit Index (+3.40%), Cell Immunotherapy (+3.18%), and PEEK Materials (+3.06%), while the sectors with declines included Military Equipment Restructuring (-1.88%) and Transgenic (-1.07%) [2] - The recombinant protein sector saw a net inflow of 389 million yuan, with 37 stocks receiving net inflows, and 6 stocks attracting over 30 million yuan in net inflows, led by Tonghua Dongbao with 48.94 million yuan [2][3] Fund Flow Analysis - The stocks with the highest net inflow ratios included *ST Wanfang (31.91%), Furuida (13.74%), and North China Pharmaceutical (12.46%) [3] - The top stocks in the recombinant protein sector by net inflow included Tonghua Dongbao (4.55% increase, 48.94 million yuan inflow), Beida Pharmaceutical (-0.77%, 46.41 million yuan inflow), and Hite Bio (5.13%, 35.56 million yuan inflow) [3][4]

证券代码：600867 证券简称：通化东宝 公告编号：2025-062 通化东宝药业股份有限公司关于 2025 年员工持股计划第一次持有人会议决议的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 一、会议召开情况 通化东宝药业股份有限公司（以下简称"公司"、"通化东宝"）2025 年员工 持股计划第一次持有人会议于 2025 年 10 月 15 日以通讯方式召开，会议通知已 于 2025 年 10 月 10 日通过书面或电子邮件的方式送达各位持有人。本次会议由 公司董事长（代行董事会秘书）李佳鸿先生召集和主持，出席本次会议的持有人 共 75 人，代表公司 2025 年员工持股计划份额合计 3,985.41 万份，占 2025 年员 工持股计划总份额的 100%。 本次会议召开符合有关法律法规、规范性文件以及《通化东宝 2025 年员工 持股计划》《通化东宝 2025 年员工持股计划管理办法》的相关规定。经与会持有 人认真审议，会议形成了如下决议： 二、会议审议情况 （一）审议通过了《关于设立 2025 年员工持股计划管理 ...

Group 1 - The core point of the news is that Tonghua Dongbao's stock price increased by 5.25% to 9.02 CNY per share, with a trading volume of 436 million CNY and a turnover rate of 2.53%, resulting in a total market capitalization of 17.666 billion CNY [1] - Tonghua Dongbao Pharmaceutical Co., Ltd. is primarily engaged in the production of biological products, with 90.29% of its revenue coming from raw materials and formulations, while medical devices account for 6.07%, traditional Chinese medicine and chemical drugs for 2.24%, and other sources for 1.27% [1] - The company was established on December 28, 1992, and went public on August 24, 1994, with its main products including hard capsules, tablets (including hormone types), granules, small-volume injections, and raw materials (recombinant human insulin) [1] Group 2 - Among the top ten circulating shareholders of Tonghua Dongbao, a fund under Yinhua Fund holds a position, having reduced its holdings by 6.308 million shares in the second quarter, now holding 11.0713 million shares, which is 0.57% of the circulating shares [2] - The fund, named Innovation Medicine (159992), has achieved a year-to-date return of 28.18%, ranking 1649 out of 4220 in its category, and a one-year return of 22.33%, ranking 2081 out of 3857 [2] - The fund manager, Ma Jun, has a tenure of 13 years and 45 days, with a total fund size of 33.304 billion CNY, achieving a best return of 144.61% and a worst return of -75.62% during his tenure [3]

Summary of Conference Call Notes Industry Overview - **Industry**: China Healthcare - **Quarter**: 3Q25 Key Companies and Revenue Growth Companies with Higher Revenue Growth 1. **United Imaging** - Expected revenue growth: **44% YoY** in 3Q25 - Growth driven by improved hospital bidding data in China [1][6] 2. **Lepu** - Expected revenue growth: **38% YoY** in 3Q25 - Growth factors: - Low base effect from 3Q24 due to "Four Same" policy impacting pharmaceutical business - Incremental revenue from consumer healthcare segment, particularly medical aesthetics [1][6] 3. **Gan & Lee Pharmaceuticals** - Expected revenue growth: **23% YoY** in 3Q25 - Benefits from insulin VBP renewal and progress in overseas expansion [1][6] Companies Under Pressure 1. **Zhifei** - Currently in the trough of its revenue cycle - Revenue expected to decline by **30% YoY** in 3Q25 - Increased competition following Wantai's launch of a 9-valent HPV vaccine - Offering discounts to accelerate inventory destocking [2][6] 2. **ICL Companies (Kingmed and Dian Diagnostics)** - Expected to post negative revenue growth in 3Q25 - Industry pricing pressure has stabilized, indicating potential for positive growth in 4Q25 [2][6] Financial Estimates and Changes - **Tonghua Dongbao**: Revised annual earnings estimates upward due to market share gains post-insulin VBP renewal [7] - **Kelun**: Revised net profit estimates downward due to ongoing price war in the API industry, while revenue estimates remain unchanged [7][10] Detailed Financial Estimates Exhibit 1: Revenue and Earnings Growth Preview - **United Imaging**: Revenue from **1,621 million** to **2,327 million** (44% YoY) - **Lepu**: Revenue from **1,402 million** to **1,937 million** (38% YoY) - **Gan & Lee**: Revenue from **930 million** to **1,140 million** (23% YoY) - **Zhifei**: Revenue from **4,528 million** to **3,177 million** (-30% YoY) [6] Exhibit 2: Updated Estimates for Tonghua Dongbao (2025E to 2027E) - **Revenue**: Increased from **2,612 million** to **2,689 million** (3.0% change) - **Net Profit**: Increased from **401 million** to **408 million** (1.5% change) [8] Exhibit 3: Updated Estimates for Kelun (2025E to 2027E) - **Revenue**: Remains at **19,029 million** (0.0% change) - **Net Profit**: Decreased from **2,791 million** to **2,686 million** (-3.8% change) [10] Risks and Methodology - **Mindray**: Target price of **Rmb314** with risks including VBP impacts and market penetration challenges [12][13] - **SNIBE**: Target price of **Rmb73** with risks from competition and policy changes [14] - **Hualan**: Target price of **Rmb19** with risks from regulatory changes and competition [15] - **Tonghua Dongbao**: Neutral rating with target price of **Rmb9**, risks from product sales ramp-up and competition [17] - **Kelun**: Neutral rating with target price of **Rmb38**, risks from API price declines [18] Conclusion - The China healthcare sector is experiencing varied growth dynamics, with certain companies like United Imaging and Lepu showing strong revenue growth, while others like Zhifei face significant challenges. The financial estimates reflect these trends, with adjustments made based on market conditions and competitive pressures.