Market Overview - The biopharmaceutical sector increased by 1.27% on February 3, with Wanzhe Co., Ltd. leading the gains [1] - The Shanghai Composite Index closed at 4067.74, up 1.29%, while the Shenzhen Component Index closed at 14127.1, up 2.19% [1] Stock Performance - Wanzhe Co., Ltd. (000534) closed at 30.65, with a rise of 10.01% and a trading volume of 313,500 shares, amounting to a transaction value of 921 million yuan [1] - Other notable performers included ST Weiming (002581) with a 5.01% increase, closing at 7.55, and Nearshore Protein (688137) with a 4.84% increase, closing at 44.20 [1] Capital Flow - The biopharmaceutical sector experienced a net outflow of 255 million yuan from institutional investors and 153 million yuan from retail investors, while retail investors saw a net inflow of 408 million yuan [2] - The capital flow for individual stocks showed that Wanzhe Co., Ltd. had a net outflow of 50.83 million yuan from institutional investors, while retail investors contributed a net inflow of 15.59 million yuan [3] Individual Stock Analysis - Eurolin Biotech (688319) had a net inflow of 21.61 million yuan from institutional investors, while ST Weiming (002581) saw a significant net inflow of 13.51 million yuan [3] - Conversely, major outflows were noted in Wanzhe Co., Ltd. and other stocks, indicating varied investor sentiment across the sector [3]

重要内容提示： ■ 一、回购股份的基本情况 通化东宝药业股份有限公司（以下简称"公司"或"通化东宝"）于2025年10月17日召开第十一届董事会第 十八次会议，审议通过了《关于以集中竞价交易方式回购公司股份方案的议案》，同意公司使用自有资 金以集中竞价交易方式回购公司股份，回购后的股份将用于员工持股计划及/或股权激励。在回购股份 价格不超过人民币10元/股（含），资金总额不低于人民币2,000万元（含），不超过人民币4,000万元 （含）。回购期限为自公司董事会审议通过回购股份方案之日起6个月内。内容详见公司于2025年10月 18日在中国证券报、上海证券报及上海证券交易所网站（www.sse.com.cn）披露的《通化东宝关于以集 中竞价交易方式回购公司股份方案的公告》《通化东宝关于以集中竞价交易方式回购股份的回购报告 书》。 二、回购股份的进展情况 2025年11月6日，公司按照股份回购方案实施了首次回购。内容详见公司于2025年11月7日在中国证券 报、上海证券报及上海证券交易所网站（www.sse.com.cn）披露的《通化东宝关于以集中竞价交易方式 首次回购公司股份的公告》（公告编号：2025-07 ...

证券代码：600867 证券简称：通化东宝 公告编号：2026-012 通化东宝药业股份有限公司 关于以集中竞价交易方式回购公司股份进展公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 特此公告。 | 回购方案首次披露日 | 2025/10/18，由董事长李佳鸿提议 | | | | | | | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | | 回购方案实施期限 | 年 2025 4 | 10 | 月 | 17 | 日~2026 | 年 | 月 | 日 16 | | 预计回购金额 | 2,000万元~4,000万元 | | | | | | | | | 回购用途 | □减少注册资本 √用于员工持股计划或股权激励 | | | | | | | | | | □用于转换公司可转债 □为维护公司价值及股东权益 | | | | | | | | | 累计已回购股数 | 3,000,000股 | | | | | | | | | 累计已回购股数占总股本比例 | ...

Core Viewpoint - Tonghua Dongbao Pharmaceutical Co., Ltd. has announced a significant profit forecast for 2025, projecting a net profit of approximately 1.242 billion yuan, highlighting the company's strong resilience and growth potential in the industry [1] Group 1: Financial Performance - The company expects a substantial recovery in its performance, driven by steady growth in its core business and positive contributions from non-recurring gains [1] - Investment income from the transfer of shares in Xiamen Te Bao Bioengineering Co., Ltd. has provided strong support for the company's performance [1] - Core profitability indicators have significantly improved due to ongoing efforts in product structure upgrades, international expansion, and innovative research and development [1] Group 2: Market Position and Product Development - As a leading player in the domestic insulin market, the sales volume of insulin analog products has become the main driver of the company's growth in 2025, with a year-on-year increase of over 100% [1] - The revenue share of insulin analogs continues to rise, facilitating a strategic transition from a focus on human insulin to a balanced development of both human insulin and insulin analogs [1] - The company has achieved significant breakthroughs in hospital access and sales for insulin analogs, laying a solid foundation for ongoing performance recovery [1] Group 3: Market Share and International Expansion - According to data from Yao Yi Magic Cube, the company ranks second in market share for human insulin and insulin analogs, with a human insulin market share of 45.5%, maintaining the top position domestically [2] - The market share of glargine insulin has steadily increased to 15.0%, while the market share of aspart insulin is rapidly expanding, contributing to a significant rise in domestic sales revenue [2] - Following a nearly 80% year-on-year growth in overseas revenue in 2024, the company continues to experience strong growth in 2025, expanding its international product registration and market presence [2] Group 4: Future Outlook - The company aims to leverage the continuous recovery of its 2025 performance to solidify its domestic insulin market position, optimize product structure, and expand market share [2] - There is a focus on accelerating international strategic initiatives, enhancing research and development efforts, and building a comprehensive pipeline to foster sustainable high-quality development [2]

Core Viewpoint - The performance of A-share pharmaceutical stocks in 2025 shows a mixed outlook, with 283 companies disclosing earnings forecasts, where 160 companies expect profit growth while over 120 companies anticipate profit declines, indicating a significant divergence in the industry [1][3]. Group 1: Profit Growth - Among the 283 pharmaceutical stocks, 160 companies are expected to see a year-on-year increase in net profit, with Sino Medical (688108) leading the pack with a projected increase of over 32 times [1][3]. - Sino Medical forecasts a net profit of 43 million to 50 million yuan for 2025, representing a year-on-year growth of 2,767% to 3,233% [3]. - Other notable companies with significant profit growth include WuXi AppTec, Hanyu Pharmaceutical, and Kangxino, with 65 companies projecting a net profit increase of over 100% [3][4]. Group 2: Profit Decline - Over 120 companies are expected to report a decline in net profit for 2025, with 39 companies facing their first losses since listing, including well-known firms like Zhifei Biological and Zhenbao Island [1][5]. - Zhifei Biological anticipates a net loss of approximately 10.698 billion to 13.726 billion yuan, marking a year-on-year decline of 630% to 780% [6][7]. - The decline in the vaccine sector is attributed to decreased public willingness to vaccinate and increased vaccine hesitancy, leading to significant performance pressure across the industry [7][8]. Group 3: Innovative Drug Companies - Several innovative drug companies are reporting positive trends, with some achieving profitability or significantly reducing losses. For instance, Nocren Pharmaceutical is expected to turn a profit for the first time, projecting a net profit of around 633 million yuan [10]. - Rongchang Biopharmaceutical is also expected to turn a profit, with a projected net profit of approximately 716 million yuan, driven by strong sales of core products [10]. - Companies like Junshi Biosciences and Amgen have not yet achieved profitability but are showing a clear trend of reduced losses, indicating a gradual transition towards commercialization and revenue growth in the innovative drug sector [11].

蓝鲸新闻2月1日讯，近日，吉林证监局发布行政监管措施决定书，剑指通化东宝药业股份有限公司、李佳鸿。 决定书显示，通化东宝药业股份有限公司存在以下问题：通化东宝与控股股东东宝实业集团股份有限公司存在部分房产互相混用情况，双方未签订相关租赁 协议，未支付租金。上述事项反映出通化东宝独立性存在不足，违反了《上市公司治理准则》有关规定，公司董事长李佳鸿对上述违规行为负主要责任。 对此，吉林证监局决定对通化东宝药业股份有限公司采取责令改正，对李佳鸿采取出具警示函的监督管理措施，并记入证券期货市场诚信档案。 ...

Group 1 - The core point of the article is that Tonghua Dongbao received a warning from the Jilin Securities Regulatory Bureau due to issues regarding the independence of the company and its major shareholder, Dongbao Industrial Group [1][3] - The company has been found to have mutual use of certain properties with its controlling shareholder without signed lease agreements or rent payments, indicating a lack of independence [3] - The chairman, Li Jiahong, is primarily responsible for these violations, and the regulatory body has decided to impose corrective measures and issue a warning letter [3] Group 2 - On January 29, Dongbao Industrial Group pledged 21 million shares of Tonghua Dongbao to China Construction Bank for debt repayment, representing 1.07% of the company's total share capital [3] - As of the announcement date, Dongbao Industrial Group holds a total of 620 million shares, with 586 million shares pledged, accounting for 29.94% of the total share capital and 94.66% of the shareholder's holdings [3] - Just days before the warning letter, Tonghua Dongbao announced a positive earnings forecast for 2025, expecting a net profit of approximately 1.242 billion yuan, marking a significant turnaround from the previous year [3][4] Group 3 - The company's turnaround in performance is attributed to two main factors: the successful bidding for insulin products in the domestic market and significant growth in other products like liraglutide injection and empagliflozin tablets [4] - Notably, a substantial portion of the net profit increase is due to a one-time gain from the sale of shares in Xiamen Te Bao Biological Engineering Co., which contributed over 800 million yuan, accounting for about 64% of the total net profit [4][5] - This indicates that the impressive performance in 2025 is largely driven by a non-recurring asset sale rather than core business operations [5]

Group 1 - The controlling shareholder of Tonghua Dongbao Pharmaceutical, Dongbao Industrial Group, and its concerted parties hold approximately 641 million shares, accounting for 32.75% of the company's total shares [1] - The total number of pledged shares by Dongbao Group and its concerted parties is about 586 million shares, representing 91.44% of their total holdings and 29.94% of the company's total shares [1] - Dongbao Group specifically holds around 620 million shares, which is 31.63% of the total shares, with a pledged amount of 586 million shares, making up 94.66% of its holdings and 29.94% of the company's total shares [1]

证券代码：600867 证券简称：通化东宝 公告编号：2026-010 通化东宝药业股份有限公司 关于控股股东股份解押及再质押公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示: 通化东宝药业股份有限公司（以下简称"公司"或"本公司"）控股股东东 宝实业集团股份有限公司（以下简称"东宝集团"）及其一致行动人合计持有公 司股份 641,362,975 股，占公司目前股份总额的 32.75%；东宝集团及其一致行 动人持有公司股份累计质押数量（本次解押及再质押后）为 586,439,472 股，占 其及一致行动人所持有公司股份总额的 91.44%，占公司目前股份总额的 29.94%。 其中：东宝集团持有公司股份 619,500,796 股，占公司目前股份总额的 31.63%， 东宝集团持有公司股份累计质押数量（本次解押及再质押后）为 586,439,472 股， 占其所持有公司股份总额的 94.66%，占公司目前股份总额的 29.94%。 2026 年 1 月 30 日,本公司接到东宝集团关于股份解押及再质押相关情况 ...

证券代码：600867 证券简称：通化东宝 公告编号：2026-011 通化东宝药业股份有限公司 关于收到吉林证监局行政监管措施决定书的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈 述或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 二、公司相关说明 公司及相关人员高度重视《决定书》中所涉问题，将严格按照相关法律法规及吉 林证监局的要求认真总结、整改。公司将加强对相关法律法规和规范性文件的学习， 不断提高信息披露质量和规范运作水平，切实维护公司及全体股东的利益，促进公司 健康、稳定、持续发展。 通化东宝药业股份有限公司（以下简称"通化东宝"或"公司"）于2026年1月30 日收到中国证券监督管理委员会吉林监管局（以下简称"吉林证监局"）下发的《关于 对通化东宝药业股份有限公司采取责令改正并对李佳鸿采取出具警示函监督管理措施的 决定》（吉证监决〔2026〕3号）（以下简称"《决定书》"），现将原文内容公告如 下： 一、《决定书》内容 通化东宝药业股份有限公司、李佳鸿： 经查，通化东宝药业股份有限公司存在以下问题： 通化东宝与控股股东东宝实业集团股份有限公司存在部分房产互相 ...