本报讯(记者袁传玺) 作为一款源头创新药物，爱谱沙具有独特的表观遗传调控机制，对肿瘤抑制性免疫微环境具有重新激活 作用，可单独或联合其他药物治疗恶性肿瘤。凭借显著疗效，爱谱沙在复发/难治性外周T细胞淋巴瘤领 域已连续八年获得中国临床肿瘤学会(CSCO)指南最高级别I级1A类证据推荐，弥漫大B细胞淋巴瘤适应 症亦获得2025年CSCO指南的最高级别推荐。 微芯生物是科创板首家过会企业及第一家上市的生物医药企业，是中国原创新药领域的先行者。此次爱 谱沙在京东健康全网独家首发，是双方深化合作、共同推动创新疗法高效可及的重要举措，将加速创新 药物的精准触达与普惠落地，为更多患者带来新的治疗希望和更优的生存获益。作为新药线上首发第一 站，京东健康将依托全渠道资源与医疗健康服务生态，为患者提供从药品咨询、在线问诊到精准用药指 导的一站式服务，助力爱谱沙快速覆盖终端市场。 日前，由深圳微芯生物科技股份有限公司自主研发的全球首创口服选择性组蛋白去乙酰化酶(HDAC)抑 制剂爱谱沙(西达本胺)在京东健康股份有限公司(以下简称"京东健康")全网独家首发。京东健康将充分 发挥全渠道优势和医疗健康服务能力，加速创新药物普惠可及，让广 ...

炒股就看金麒麟分析师研报，权威，专业，及时，全面，助您挖掘潜力主题机会！ 文/新浪财经上海站 陈秀颖 2025年上半年，中国创新药行业在政策红利与国际化突破的双重助力下迎来高光时刻，Wind数据显 示，A股创新药板块80家企业中，16家已发布中报预告。头部企业凭借技术壁垒与商业化能力实现爆发 式增长。 | 证券简称 | 预告净利润同比增长 | | 预告净利润同比增 董事长 | 总经理 | | --- | --- | --- | --- | --- | | | 上限 | 长下限 | | [交易日期] 最新 [交易日期] 最新 | | | [报告期] 今年中报 | [报告期] 今年中报 | | | | | [单位] %↓ | [单位] % | | | | 双鹭药业 | 356.24 | | 237.95 徐明波 | 徐明波 | | 全诺生物 | 332.10 | | 253.54 文永均 | 文永均 | | 步长制药 | 205.94 | | 110.88 赵涛 | #x15 | | 通化东宝 | 194.30 | | 194.30 李佳鸿 | 冷春生 | | 微芯生物 | 173.00 | | 173.00 X ...

Group 1 - The core viewpoint of the articles highlights the growing trend of companies listed on the Sci-Tech Innovation Board (STAR Market) in China expanding their operations internationally, leveraging their proprietary technologies and high-value products to compete in global markets [1][2]. - In 2024, the total overseas revenue of STAR Market companies is projected to reach 430.36 billion RMB, marking a year-on-year increase of 6.1%, with 173 companies experiencing over 30% growth in overseas revenue [1]. - The characteristics of STAR Market companies' international expansion include diverse models such as independent overseas operations and licensing collaborations, as well as a focus on developing First-in-Class and Best-in-Class drugs [1][2]. Group 2 - Unlike early "going global" enterprises that relied on cost advantages, STAR Market companies are competing in high-end markets with high technology, high research and development, and high added value [2]. - Companies like YK Cloud have transitioned from providing cloud services to exporting AI capabilities, with their AI computing platform supporting flexible scheduling of domestic and international chips [2]. - The export of high-value products and the synergy between technology and capital are key support points for the development of STAR Market companies [2]. Group 3 - For STAR Market companies to achieve stable and long-term international expansion, a robust support system is essential, including improved cross-border financing mechanisms and enhanced regulatory cooperation with overseas capital markets [3]. - Companies need to enhance their international operational capabilities, conduct thorough research on overseas markets, and develop suitable overseas strategies [3]. - Emphasis should be placed on cultivating international management teams and technical talent to improve operational management levels abroad [3].

Summary of Key Points Core Viewpoint - On July 18, a total of 16 stocks on the Sci-Tech Innovation Board (STAR Market) experienced block trading, with a cumulative transaction amount of 171 million yuan, indicating active trading activity in this sector [1]. Group 1: Trading Activity - A total of 31 block trades were recorded, with a cumulative trading volume of 4.8367 million shares [1]. - The stock with the highest transaction amount was Haitan Ruisheng, which had 9 block trades totaling 38.30 million shares and a transaction amount of 38.30 million yuan [1]. - Other notable stocks in terms of transaction amounts included Guangyun Technology and Fuchuang Precision, with transaction amounts of 24.9162 million yuan and 20.9360 million yuan, respectively [1]. Group 2: Price and Discount Analysis - The stocks that experienced the highest discount rates relative to their closing prices included Qingyun Technology, Weixin Bio, and Guangyun Technology, with discount rates of 19.48%, 17.25%, and 14.95%, respectively [1]. - The average increase for the stocks involved in block trading was 2.55%, with the top gainers being Dema Technology, Qingyun Technology, and Huasheng Lithium, which saw increases of 14.74%, 7.90%, and 7.22% respectively [1]. Group 3: Institutional Participation - Among the block trades, 12 transactions involved institutional buyers or sellers, with the highest buying amounts for Haitan Ruisheng, Guangyun Technology, and Qingyun Technology, at 27.70 million yuan, 11.2276 million yuan, and 7.579 million yuan, respectively [2]. - In terms of net capital flow, six stocks saw net inflows, with Dema Technology, Huasheng Lithium, and Qingyun Technology leading with net inflows of 51.1035 million yuan, 33.284 million yuan, and 32.1246 million yuan, respectively [2].

Group 1 - Chinese assets are experiencing a resurgence, with NIO and Li Auto rising nearly 7% as foreign investment increases in A-shares [2] - The Invesco Global Sovereign Asset Management Research indicates a noticeable recovery in interest from international investment institutions towards the Chinese market, managing approximately $27 trillion in assets [2] - Several foreign institutions express optimism about Chinese assets due to the stable economic performance, policy benefits, and improved corporate earnings outlook [2] Group 2 - The U.S. House of Representatives has advanced cryptocurrency legislation, supported by President Trump, which has led to significant stock price increases for companies in the crypto sector [3] - Blue Ocean Interactive surged over 45% after announcing the establishment of LK Crypto, focusing on mainstream crypto asset management and RWA [3] - Hong Kong is actively developing stablecoin products, creating a dual regulatory framework that connects the U.S. dollar stablecoin with the mainland [3] Group 3 - The Hong Kong IPO market is witnessing a surge, with a significant increase in financing amounts, reflecting global capital's confidence in China's industrial upgrade and consumption potential [7] - On July 9, the Hong Kong Stock Exchange saw five companies queueing for listing in a single day, raising over 10 billion HKD [7] Group 4 - The domestic consumption and investment policies are being emphasized by the Chinese government to strengthen the domestic circulation [5][6] - Analysts highlight the urgency and necessity of promoting consumption as a core strategy for economic growth [6] Group 5 - The A-share market has seen an increase in financing balance for eight consecutive days, totaling an increase of 44.038 billion CNY, indicating positive market sentiment [10] - Analysts suggest that the current macro environment and market risk appetite signal potential for further market growth [10] Group 6 - The number of private equity MOM products registered this year has reached a new high, with 43 products registered by July 15, surpassing the total for the past nine years [14] - This trend indicates a strong interest in the MOM fund model, which allows for diversified asset management [14] Group 7 - The beverage brand Wahaha is facing a decline in sales following a family dispute involving its chairman, which has raised concerns among distributors [16] - The internal family conflict could potentially disrupt the competitive landscape of the Chinese beverage industry [16] Group 8 - The domestic electric vehicle market is seeing significant growth, with L2-level assisted driving penetration exceeding 50% [18] - The heavy truck sales in the first half of the year have increased by approximately 7%, with new energy heavy trucks being a major highlight [18] Group 9 - The stock market is experiencing fluctuations, with the Shanghai Composite Index slightly declining by 0.03% to 3503.78 points [19] - The Hong Kong market is also showing mixed performance, with the Hang Seng Index and the Hang Seng Tech Index experiencing slight declines and gains, respectively [19] Group 10 - The U.S. stock market has seen gains driven by positive economic data and corporate earnings reports, with the S&P 500 rising by 0.45% [20] - Approximately 88% of S&P 500 companies that have reported earnings exceeded analyst expectations, boosting investor confidence [20] Group 11 - Several foreign investment banks have expressed positive views on the Chinese market, with Citigroup raising its ratings for Chinese and Korean markets to "overweight" [21] - Citigroup projects the Hang Seng Index to reach 25,000 points by the end of the year and the CSI 300 Index to reach 4,200 points [21] Group 12 - The stock market's investment logic is shifting towards cash flow analysis in a low-interest-rate environment, with a focus on high-dividend and strong cash flow companies [22] - Analysts are optimistic about sectors such as automotive, electronics, and traditional high-growth areas like AI and pharmaceuticals [22]

Group 1: US Market Performance - Strong retail sales data and a decrease in initial jobless claims led to a rise in the US dollar and stock market, with the S&P 500 and Nasdaq closing at new highs [1][2] - The S&P 500 index rose by 0.54%, the Dow Jones increased by 0.52%, and the Nasdaq gained 0.74% [2] Group 2: Company Earnings and Stock Movements - Netflix's stock dropped by 2% after its earnings report, while PepsiCo's shares rose by 7.4% [3] - Microsoft and Nvidia both saw approximately 1% increases in their stock prices [3] - TSMC reported better-than-expected earnings, with its ADR rising by 3.38%, marking three consecutive days at historical highs [3] Group 3: Bond and Commodity Markets - The 2-year US Treasury yield rose by over 3 basis points, while the dollar appreciated by 0.33% [4] - Gold prices fell by over 1.1% before rebounding, ultimately closing down by 0.28% [5] - Oil prices initially dropped but later increased, with US crude rising nearly 2% from its daily low [5] Group 4: AI and Technology Developments - Nvidia's VP announced plans to port CUDA to the RISC-V architecture, indicating strong demand for AI chips [12][16] - TSMC's Q2 net profit surged by 61%, exceeding expectations, with a projected sales growth of about 30% for the year [12] Group 5: Investment Strategies and Market Trends - Dongfang Securities noted that the Shanghai Composite Index has remained above 3500 points for six trading days, indicating a potential upward trend in the market [13] - The technology sector, particularly AI, robotics, and semiconductors, is expected to remain a long-term focus for investors [13] Group 6: Industry-Specific Developments - Chongqing issued a plan to cultivate the recycling industry for new energy vehicle batteries, aiming for a 90% coverage rate by 2027 [9] - Shanghai's health departments released guidelines to promote the transformation of scientific achievements in medical institutions [10] Group 7: New Financial Products - Huaxia Fund (Hong Kong) launched two tokenized money market funds, including the world's first RMB tokenized fund [11]

Policy Developments - The National Medical Products Administration (NMPA) has released a draft for public consultation regarding the adjustment of medical device classifications, aiming to optimize the registration and filing requirements for medical devices [1] Drug Approval - Yuyuan Pharmaceutical's YKYY029 injection has received clinical trial approval for treating hypertension, marking a significant step in the development of a novel siRNA drug [2] - Hengrui Medicine has received clinical trial approvals for four drugs, including SHR-8068 injection and Abediterib injection, with total R&D investments amounting to approximately 20.33 million yuan [3] Financial Reports - Microchip Biotech expects a net profit of 30.06 million yuan for the first half of 2025, driven by increased sales from new drug listings and optimized sales strategies [4] - China National Pharmaceutical Modern reported a 6.46% decline in net profit for the first half of the year, attributed to decreased sales and prices of certain antibiotics and other products [5] Capital Market - Tigermed announced the sale of its stake in Lixin Pharmaceutical for approximately 34.11 million USD, reflecting a strategic move in the context of the domestic pharmaceutical industry's consolidation [6] Industry Events - A breakthrough in brain-computer interface technology has been achieved in Shanghai, allowing patients with speech impairments to communicate through decoded brain activity [8] - Yuan Da Pharmaceutical's innovative nasal spray for dry eye treatment has received approval and its first prescriptions have been issued, providing a new treatment option for patients [9] Debt Resolution - Kangmei Pharmaceutical has reached a settlement agreement to resolve historical debt issues for 43.5 million yuan, facilitating the closure of related legal matters [10] Market Sentiment - Weier Pharmaceutical announced plans for its employee stock ownership platform to reduce its holdings by up to 1% of the company's shares, driven by shareholder funding needs [11]

Group 1 - Tigermed announced the sale of its stake in Lixin Pharmaceutical, holding a direct stake of 3.41% and an indirect stake of 4.58% through fund holdings, with the total transaction valued at approximately $34.11 million [1] - The sale reflects Tigermed's ability to achieve investment returns and demonstrates its professional post-investment management capabilities as a leading CRO [1] Group 2 - Yuan Da Pharmaceutical's innovative nasal spray product for dry eye treatment, OC-01, has received approval from the National Medical Products Administration and its first commercial prescriptions have been implemented [2] - The product's launch enhances Yuan Da's ophthalmology pipeline and signifies its strategic shift from a traditional pharmaceutical company to an innovative one, with future market performance being promising [2] Group 3 - China Pharmaceutical's general manager, Hu Huidong, has resigned due to work adjustments, which may lead to new development strategies if a new management team with rich industry experience is appointed [3] - The impact of this leadership change should be evaluated in conjunction with the company's fundamentals and subsequent announcements [3] Group 4 - Microchip Biotech expects a significant increase in net profit by 173% for the first half of 2025, with revenue projected at 407.29 million yuan, a 35% year-on-year increase [4] - The company is entering a harvest phase due to its independent R&D capabilities, validating its "small but beautiful" commercialization path, although it must continue to advance its pipeline and manage potential policy risks for sustained growth [4]

Core Viewpoint - Multiple listed companies in the Shanghai and Shenzhen markets have announced significant developments, including changes in control, asset sales, investments, and performance forecasts, which may present investment opportunities and risks for investors. Group 1: Control Changes and Major Transactions - Helen Piano's actual controllers are planning a change in control, leading to a suspension of trading starting July 18, 2025, for up to two trading days [3] - Tiger Medical is selling 95.09% of its stake in Lixin Pharmaceutical for approximately $34.11 million [4] - ST Lifan announced that its operational situation has not changed significantly despite a stock price fluctuation of 42.54% over two trading days [9] Group 2: Investments and Acquisitions - Sdic plans to invest approximately 509 million yuan in expanding its high-end functional film production capacity [5] - Dongfang Yuhong's subsidiary intends to acquire 100% of Chile's Construmart for about $123 million [6] - Huaitian Thermal Power has been recommended as the owner of a 700,000 kW wind power project, aligning with its investment strategy [7] Group 3: Performance Announcements - Hangzhou Bank reported a net profit of 11.662 billion yuan for the first half of the year, a year-on-year increase of 16.67% [14] - Tuojing Technology expects a net profit increase of 101% to 108% in Q2 2025, driven by new product breakthroughs [15] - Weicheng Bio anticipates a net profit of 30.06 million yuan for the first half of 2025, reversing a loss from the previous year [17] Group 4: Contracts and Strategic Partnerships - State Grid Information won contracts totaling 966 million yuan from the State Grid Corporation [21] - Beizhi Technology signed a contract worth 164 million yuan with a major client [22] - Mould Technology received a project letter of intent for exterior parts with an expected total sales of 2.044 billion yuan [23] Group 5: Shareholding Changes - Huasheng Lithium plans to reduce its shareholding by up to 2.24% [25] - Yutai Micro's shareholder intends to reduce holdings by up to 3% due to personal funding needs [26] - Alter's controlling shareholder plans to reduce holdings by up to 3% [27]

Mergers and Acquisitions - Dongfang Yuhong plans to acquire 100% equity of Chilean building materials retailer Construmart S.A. for approximately $123 million [1] Major Asset Restructuring - Hongming Co. has terminated its plan to acquire 83% equity of Shenzhen Chisu Automation Equipment Co. due to failure to reach a final agreement [2] Performance Disclosure - Sumeida reported a net profit of 646 million yuan for the first half of the year, a year-on-year increase of 12.62%, with total revenue of 55.101 billion yuan, down 1.52% [3] - Jintong Co. reported a net profit of 1.38 billion yuan for the first half of 2025, a year-on-year decrease of 8.45%, with total revenue of 6.959 billion yuan, up 5.55% [4] - Microchip Biotech expects a net profit of approximately 30.06 million yuan for the first half of 2025, a year-on-year increase of 173%, with revenue expected to be around 407 million yuan, up 35% [5] Shareholding Changes - Huasheng Lithium plans to reduce its shareholding by up to 2.24%, equating to a maximum of 3.567 million shares [6] - Yutai Micro's shareholder Li Haihua intends to reduce his stake by up to 3%, totaling no more than 2.4 million shares [7] - Hongqiang Co.'s controlling shareholder Liu Lianjun plans to reduce his stake by up to 3%, amounting to no more than 6.3478 million shares [8] Legal Issues - Jintong Ling has been prosecuted for financial fraud and false issuance of stocks, accused of providing false financial data for six consecutive years, resulting in significant investor losses [9][10]