华泰联合证券有限责任公司（以下简称"华泰联合证券"、"保荐人"）作为 江苏东星智慧医疗科技股份有限公司（以下简称"东星医疗"、"公司"）首次公 开发行股票并创业板上市的保荐人，根据《深圳证券交易所上市公司自律监管指 引第 13 号——保荐业务》《深圳证券交易所创业板股票上市规则》和《深圳证券 交易所上市公司自律监管指引第 2 号——创业板上市公司规范运作》等法规和规 则的相关规定以及东星医疗的实际情况，认真履行保荐人应尽的职责，对东星医 疗的董事、监事、高级管理人员等相关人员进行了有计划、多层次的后续培训， 所培训的内容严格按照中国证券监督管理委员会及深圳证券交易所创业板有关 持续督导的最新要求进行。 2025 年 4 月 14 日，华泰联合证券相关人员按照《深圳证券交易所上市公司 自律监管指引第 13 号——保荐业务》的要求完成了对东星医疗董事、监事、高 级管理人员等相关人员的持续培训工作，特向贵所报送培训工作报告。 一、培训的主要内容 华泰联合证券有限责任公司 关于江苏东星智慧医疗科技股份有限公司持续督导期 2024年培训情况报告 深圳证券交易所： 根据《深圳证券交易所上市公司自律监管指引第 13 号—— ...

华泰联合证券有限责任公司 关于江苏东星智慧医疗科技股份有限公司 2024 年度跟踪报告 | 保荐人名称：华泰联合证券有限责任公司 | 被保荐公司简称：东星医疗 | | --- | --- | | 保荐代表人姓名：庄晨 | 联系电话：025-83388070 | | 保荐代表人姓名：黄飞 | 联系电话：025-83388070 | | 事项 | 存在的问题 | 采取的措施 | | --- | --- | --- | | 1.信息披露 | 无 | 不适用 | | 2.公司内部制度的建立和执行 | 无 | 不适用 | | 3．"三会"运作 | 无 | 不适用 | | 4.控股股东及实际控制人变动 | 无 | 不适用 | | 5.募集资金存放及使用 | 无 | 不适用 | | 6.关联交易 | 无 | 不适用 | | 7.对外担保 | 无 | 不适用 | | 8.购买、出售资产 | 无 | 不适用 | | 9.其他业务类别重要事项（包 | | | | 括对外投资、风险投资、委托 | 无 | 不适用 | | 理财、财务资助、套期保值 | | | | 等） | | | | 10．发行人或者其聘请的证券 | 无 | 不适用 ...

Policy Developments - The National Medical Products Administration (NMPA) approved the registration of 308 medical device products as of March 2025, including 248 domestic Class III medical devices, 34 imported Class III medical devices, 19 imported Class II medical devices, and 7 medical devices from Hong Kong, Macau, and Taiwan [1] Drug Approvals - Chengdu Saijing Bio's ursodeoxycholic acid oral suspension has been approved as the first domestic generic Class 3.1 new drug for treating cystic fibrosis-associated liver disease (CFALD), filling a gap in the market for this indication [2] - Kowa Company's pemafibrate tablets have been approved in China for the treatment of dyslipidemia [3] - Merck Sharp & Dohme (MSD) announced that its nine-valent HPV vaccine has received approval for male use in China, targeting males aged 16-26, enhancing public awareness of HPV infections in men [5] Capital Market - Zhongjie Chaorun completed a Pre-A round financing of several million yuan, primarily for clinical trials of its artificial meniscus implant and commercialization of its innovative meniscus suturing device [4] Financial Reports - Aoyang Health reported a 2024 revenue of 2.01 billion yuan, a year-on-year decrease of 7.54%, with a net profit of 40.56 million yuan, down 18.36% [6] - Novogene announced a total revenue of 2.111 billion yuan for 2024, a year-on-year increase of 5.45%, with a net profit of 197 million yuan, up 10.52% [7] - Tianyi Medical reported a revenue of 419 million yuan for 2024, a year-on-year increase of 9.98%, but a net loss of 744,000 yuan [8] - Luoxin Pharmaceutical disclosed a net loss of 962 million yuan for 2024, despite a revenue increase of 11.99% to 2.647 billion yuan [9] - Dongxing Medical reported a revenue of approximately 435 million yuan for 2024, a slight increase of 0.4%, with a net profit of about 97.42 million yuan, up 0.21% [10] Public Sentiment - Xinbang Pharmaceutical announced the resignation of independent director Zhou Jun, with the company reporting a revenue of 6.032 billion yuan for 2024, down 6.63%, and a net profit of 101 million yuan, down 64.70% [11] - Shuangcheng Pharmaceutical warned of potential delisting risk due to expected negative net profit and revenue below 300 million yuan for 2024 [12]

Group 1 - Company Instech reported a net profit of 177 million yuan for 2024, a year-on-year increase of 28.15%, with a proposed cash dividend of 1.20 yuan per 10 shares [1] - Instech achieved an operating revenue of 1.185 billion yuan in 2024, representing a year-on-year growth of 24.45% [1] - The company specializes in the research, production, and sales of rare earth permanent magnet materials and applications [2] Group 2 - Company Junda reported a net loss of 106 million yuan for Q1 2025, transitioning from profit to loss, with a year-on-year revenue decline of 49.52% [3] - Junda's operating revenue for Q1 2025 was 1.875 billion yuan [3] - The company focuses on the research, production, and sales of photovoltaic cell products [4] Group 3 - Company Annada reported a net loss of 10.26 million yuan for Q1 2025, with a year-on-year revenue increase of 1.44% [5] - Annada's operating revenue for Q1 2025 was 473 million yuan [5] - The company specializes in titanium dioxide and iron phosphate products [6] Group 4 - Company Jiuzhou Pharmaceutical reported a net profit of 250 million yuan for Q1 2025, a year-on-year increase of 5.68% [7] - Jiuzhou's operating revenue for Q1 2025 was 1.49 billion yuan, reflecting a year-on-year growth of 0.98% [7] - The company provides custom research and production services for pharmaceutical companies and research institutions [8] Group 5 - Company Yitong Century won a 1.48 billion yuan contract for a 5G comprehensive maintenance project with Guangdong Unicom [9] - The project will enhance the company's business volume and expansion in Guangdong [9] - Yitong Century specializes in communication network technology services and solutions [10] Group 6 - Company Rijiu Optoelectronics reported a net profit of 67.47 million yuan for 2024, a year-on-year increase of 506.9%, with a proposed cash dividend of 2.00 yuan per 10 shares [10] - Rijiu's operating revenue for 2024 was 583 million yuan, representing a year-on-year growth of 22% [10] - The company focuses on the research, production, and sales of touch display application materials [11] Group 7 - Company Ruotong reported a net profit of 95.98 million yuan for 2024, a year-on-year increase of 0.91%, with a proposed cash dividend of 2.00 yuan per 10 shares [12] - Ruotong's operating revenue for 2024 was 408 million yuan, reflecting a year-on-year growth of 7.54% [12] - The company specializes in drilling and completion equipment for oil and gas [13] Group 8 - Company Shuangxiang reported a net profit of 472 million yuan for 2024, a year-on-year increase of 754.84%, with a proposed cash dividend of 1.50 yuan per 10 shares [14] - Shuangxiang's operating revenue for 2024 was 2.29 billion yuan, representing a year-on-year growth of 51.55% [14] - The company focuses on synthetic leather and optical-grade PMMA products [15] Group 9 - Company Xinfang Pharmaceutical reported a net profit of 101 million yuan for 2024, a year-on-year decrease of 64.70%, with a proposed cash dividend of 0.30 yuan per 10 shares [16] - Xinfang's operating revenue for 2024 was 6.032 billion yuan, reflecting a year-on-year decline of 6.63% [16] - The company is involved in medical services, pharmaceutical distribution, and manufacturing [17] Group 10 - Company Dongxing Medical reported a net profit of 97.42 million yuan for 2024, a year-on-year increase of 0.21%, with a proposed cash dividend of 6.00 yuan per 10 shares [18] - Dongxing's operating revenue for 2024 was 435 million yuan, reflecting a year-on-year growth of 0.40% [18] - The company specializes in surgical medical devices [19] Group 11 - Company Wuzhou Special Paper reported a net profit of 64.68 million yuan for Q1 2025, a year-on-year decrease of 51.56%, with an operating revenue of 1.989 billion yuan [20] - Wuzhou's operating revenue for Q1 2025 increased by 15.21% [20] - The company focuses on the research, production, and sales of mechanism paper and pulp [21] Group 12 - Company Jinrui Mining expects a net profit of 15.28 million yuan for Q1 2025, a year-on-year increase of 617.40% [22] - The company specializes in the production and sales of strontium salt products [23] Group 13 - Company Youyan New Materials expects a net profit of 60 million to 75 million yuan for Q1 2025, a year-on-year increase of 13076% to 16370% [24] - The company focuses on electronic films, precious metal materials, and rare earth materials [25] Group 14 - Company Guoli expects a net profit of 11 million to 13 million yuan for Q1 2025, a year-on-year increase of 164.38% to 212.45% [26] - The company specializes in urban infrastructure design, construction, and investment [27] Group 15 - Company Shenzhen Airport reported a passenger throughput of 5.5422 million in March, a year-on-year increase of 8.70% [28] - The airport's cargo throughput was 171,900 tons, reflecting a year-on-year growth of 14.51% [28] - The company is involved in aviation and related non-aviation businesses [29] Group 16 - Company Shenghui Integration reported an order balance of 2.117 billion yuan as of March 31, 2025, a year-on-year increase of 11.89% [30] - The company provides cleanroom engineering and electromechanical engineering services [31] Group 17 - Company Chengyi Pharmaceutical received a drug registration certificate for Mercaptopurine tablets [32] - The drug is applicable for various diseases including choriocarcinoma and acute lymphoblastic leukemia [32] Group 18 - Company Enhua Pharmaceutical initiated Phase I clinical trials for NH280105 capsules, targeting Alzheimer's disease [33] - The trial aims to assess the safety and pharmacokinetics of the drug [33] Group 19 - Company Lingang Steel proposed a share buyback of 50 million to 100 million yuan [34] - The company specializes in the production and development of metallurgical products [35] Group 20 - Company Fujia plans to repurchase shares worth 15 million to 30 million yuan [36] - The company focuses on smart cleaning appliances and key components [37] Group 21 - Company Mould Technology received a project designation letter for exterior parts from a luxury car client, with an estimated total sales of 2.07 billion yuan [38] - The project is expected to start mass production in April 2027 [38] Group 22 - Company Longxin General expects a net profit of 4.55 billion to 5.30 billion yuan for Q1 2025, a year-on-year increase of 76.65% to 105.77% [39] - The company specializes in motorcycles, engines, and general machinery products [40] Group 23 - Company Dongfang Securities reported a net profit of 1.436 billion yuan for Q1 2025, a year-on-year increase of 62.08% [41] - The company focuses on investment management and securities trading [42] Group 24 - Company Yalian Machinery plans to use up to 800 million yuan of idle funds for low-risk financial products [43] - The company specializes in the production of engineered wood production lines and equipment [44] Group 25 - Company Guanghua Technology reported a net loss of 205 million yuan for 2024, with total revenue of 2.589 billion yuan [45] - The company focuses on PCB chemicals and lithium battery materials [46] Group 26 - Company Boya Biotechnology plans to publicly transfer 80% of its subsidiary's equity for 213 million yuan [47] - The transaction aims to optimize resource allocation focusing on blood products [48] Group 27 - Company Darui Electronics plans to repurchase shares worth 30 million to 50 million yuan [49] - The company specializes in customized components and automation equipment [50] Group 28 - Company Hongying Intelligent plans to repurchase shares worth 30 million to 40 million yuan [51] - The company focuses on smart control products and assemblies [52] Group 29 - Company Guangku Technology announced a change in the upper shareholding structure of its controlling shareholder [53] - The operational activities of the company will not be materially affected [54] Group 30 - Company Dingjie Smart's application for convertible bond issuance has been accepted by the Shenzhen Stock Exchange [55] - The company provides digital and intelligent solutions for various industries [56]

二○二四年度 内部控制审计报告 信会师报字[2025]第 ZA10886 号 江苏东星智慧医疗科技股份有限公司全体股东： 按照《企业内部控制审计指引》及中国注册会计师执业准则的相 关要求，我们审计了江苏东星智慧医疗科技股份有限公司（以下简称 东星医疗）2024 年 12 月 31 日的财务报告内部控制的有效性。 江苏东星智慧医疗科技股份有限公司 内部控制审计报告 三、 内部控制的固有局限性 内部控制具有固有局限性，存在不能防止和发现错报的可能性。 此外，由于情况的变化可能导致内部控制变得不恰当，或对控制政策 和程序遵循的程度降低，根据内部控制审计结果推测未来内部控制的 有效性具有一定风险。 内控审计报告 第 1 页 四、 财务报告内部控制审计意见 我们认为，东星医疗于 2024 年 12 月 31 日按照《企业内部控制 基本规范》和相关规定在所有重大方面保持了有效的财务报告内部控 制。 立信会计师事务所 中国注册会计师： 一、 企业对内部控制的责任 按照《企业内部控制基本规范》、《企业内部控制应用指引》、《企 业内部控制评价指引》的规定，建立健全和有效实施内部控制，并评 价其有效性是东星医疗董事会的责任。 二 ...

江苏东星智慧医疗科技股份有限公司 审计报告及财务报表 二○二四年度 江苏东星智慧医疗科技股份有限公司 审计报告及财务报表 （2024 年 01 月 01 日至 2024 年 12 月 31 日止） | | 目录 | 页次 | | --- | --- | --- | | 一、 | 审计报告 | 1-5 | | 二、 | 财务报表 | | | | 合并资产负债表和母公司资产负债表 | 1-4 | | | 合并利润表和母公司利润表 | 5-6 | | | 合并现金流量表和母公司现金流量表 | 7-8 | | | 合并所有者权益变动表和母公司所有者权益变动表 | 9-12 | | | 财务报表附注 | 1-97 | 审计报告 信会师报字[2025]第 ZA10883 号 江苏东星智慧医疗科技股份有限公司全体股东： 一、 审计意见 我们审计了江苏东星智慧医疗科技股份有限公司（以下简称东星 医疗）财务报表，包括 2024 年 12 月 31 日的合并及母公司资产负债 表，2024 年度的合并及母公司利润表、合并及母公司现金流量表、 合并及母公司所有者权益变动表以及相关财务报表附注。 我们认为，后附的财务报表在所有重大方面 ...

江苏东星智慧医疗科技股份有限公司 独立董事2024年度述职报告 （上官俊杰） 各位股东及股东代表： 本人上官俊杰作为江苏东星智慧医疗科技股份有限公司（以下简称"公司"） 的独立董事，严格按照《中华人民共和国公司法》《上市公司独立董事管理办法》 《深圳证券交易所上市公司自律监管指引第 2 号——创业板上市公司规范运作》 等法律、法规以及及《公司章程》《独立董事工作制度》的相关规定和要求，本 着客观、公正、独立的原则勤勉尽责、独立履职，及时了解公司的生产经营及发 展情况，促进公司规范运作、健康发展，维护公司、全体股东特别是中小股东的 利益。现将本人2024年度任职期间内工作情况报告如下： 本人上官俊杰，1978年2月出生，中国国籍，无境外永久居留权，本科学历， 律师。2001年9月至2003年8月，担任中共常州市武进区委党校教师；2003年9月 至2015年12月，担任江苏日月泰律师事务所律师；2016年1月至2019年12月，担 任江苏常元律师事务所主任；现任江苏常武律师事务所主任，常州市律师协会监 事会副监事长，江苏省律师协会监事会监督委员，常州市仲裁委仲裁员，常州市 政府法律智库智库成员，常州长青科技股份有 ...

江苏东星智慧医疗科技股份有限公司 独立董事2024年度述职报告 （蒋海洪离任） 各位股东及股东代表： 报告期内，2024年1月1日至2024年7月12日，本人蒋海洪作为江苏东星智慧医 疗科技股份有限公司（以下简称"公司"）第三届董事会的独立董事，严格按照《 中华人民共和国公司法》《中华人民共和国证券法》《上市公司独立董事管理办 法》《深圳证券交易所上市公司自律监管指引第 2 号——创业板上市公司规范运 作》等法律、法规以及《公司章程》《独立董事工作制度》的相关规定和要求， 本着客观、公正、独立的原则勤勉尽责、独立履职，及时了解公司的生产经营及 发展情况，促进公司规范运作、健康发展，维护公司、全体股东特别是中小股东 的利益。 2024年7月12日，本人任期届满，不再担任公司董事会独立董事及董事会专 门委员会相关职务，现将本人2024年度任职期间内工作情况报告如下： 本人蒋海洪，男，1979年4月出生，中国国籍，无境外永久居留权，法律博 士。2006年8月至2015年5月，担任上海医疗器械高等专科学校管理系教研室主任； 2015年5月至今，担任上海健康医学院医疗器械学院专业（系）主任。现任上海 瀛泰律师事务所高级 ...

江苏东星智慧医疗科技股份有限公司 独立董事2024年度述职报告 （徐光华离任） 各位股东及股东代表： 本人徐光华于2024年1月1日至2024年7月12日担任江苏东星智慧医疗科技股 份有限公司（以下简称"公司"或"东星医疗"）第三届董事会的独立董事，任职期 间，本人严格按照《公司法》《证券法》《上市公司独立董事管理办法》《深圳 证券交易所上市公司自律监管指引第 2 号——创业板上市公司规范运作》等相关 法律法规、规范性文件及《公司章程》《独立董事工作制度》的有关规定和要求， 本着对全体股东负责的态度，忠实勤勉地履行职责，积极关注公司经营状况，按 规定出席相关会议，认真审议董事会各项议案，充分发挥独立董事的独立作用， 对董事会的相关事项发表事前认可或独立意见，维护了公司和股东特别是中小股 东的利益。 2024年7月12日，本人任期届满，不再担任公司董事会独立董事及董事会专 门委员会相关职务，现将本人2024年度任职期间内履行独立董事职责情况汇报 如下： 本人徐光华，男，1963年4月出生，中国国籍，无境外永久居留权，管理学 博士。1985年7月至1994年8月，历任江苏科技大学助教、讲师；1994年9月至 20 ...

（沈世娟） 江苏东星智慧医疗科技股份有限公司 独立董事2024年度述职报告 本人自2024年7月12日起担任公司第四届董事会独立董事，任期与本届董事会 一致，作为江苏东星智慧医疗科技股份有限公司（以下简称"公司"）的独立董 事，严格按照《公司法》《上市公司独立董事管理办法》《深圳证券交易所创业 板股票上市规则》及《公司章程》等法律法规及规范性文件的要求，忠实、勤勉 地履行独立董事职责，积极维护公司整体利益及全体股东尤其是中小股东的合法 权益。现将本人2024年度任职期间的履职情况汇报如下： 尊敬的各位股东及代表： 本人沈世娟，1970年4月出生，中国国籍，无境外永久居留权，苏州大学法 学硕士，常州大学法学教授，国家知识产权高层次人才，专利代理师，2001年2 月至今历任常州大学讲师、副教授、教授；2022年10月至今任常州银河世纪微电 子股份有限公司独立董事；2023年1月至今任江苏海鸥冷却塔股份有限公司独立 董事；2024年7月至今任公司独立董事。 在担任公司独立董事期间，本人未在公司担任除独立董事以外的任何职务， 也未在公司主要股东公司担任任何职务，不存在任何可能妨碍其进行独立客观判 断的关系，不存在影响 ...