随着我国经济快速发展和人民生活水平的提高，急性心肌梗死的发病率与死亡率逐年升高。秋冬季更是心血管疾病的高发期，气温的下降不仅带来了寒 冷，也增加了心梗的发生风险。 审核专家：中国医学科学院阜外医院心内科副主任医师 安涛 刚垫,机云山巩仪化。 2人 武好医生 小时： 好： 典型症状 前胸剧烈疼痛,呈现压榨性、 闷痛或紧缩感,持续时间超过 15分钟,经休息和含服硝酸甘 油无效。 2.胸部压迫感( 像有块大石头压在胸口,感觉 闷、堵、胀痛,可能持续几分钟 或反复出现。 不典型症状 l.放射性疼痛( 胸部疼痛扩散到左肩、手臂 部、下颌或牙床,表现为 或酸痛。女性患者更易出 种不典型症状。 2.头晕乏力 ( 突然乏力虚弱,全身发 冷，头昏脑胀甚至晕倒昏 l.剧烈胸痛 ( 3.消化道不适 : FEE | FEATS ttp://www.f 3.伴随症状( 常伴有大汗淋漓、面色苍白、 呼吸困难、恶心呕吐、头晕甚 e量厥。 上腹疼痛、恶心、胃灼热 吐,容易与胃肠疾病混淆。 4.糖尿病患者 可能无痛，仅表现为气短， 如果发现自己出现了这些症状,切勿疏忽大意, 保持冷静,及时采取自救措施并立即就医。 9人的医生 all his ...

撰文丨王聪 该研究开发了 按需挤出 （ extrusion-on-demand， EoD ） 生物打印技术，构建出具有微米级结构保真度 （内膜、中膜和外膜） 与可定制宏观 几何形状的 动脉模型 ，再现了血管疾病中的协同微环境相互作用， 可用于解析心血管疾 病机制、评估微环境特异性疗法，从而推动心血管疾病的个性化治疗革新。 编辑丨王多鱼 排版丨水成文 心血管疾病 是全球头号致死病因，然而，由于缺乏能够真实再现人体动脉复杂环境的实验室模型，预防和治 疗心血管疾病的研究一直受阻。在患者身上，血管疾病是由结构重塑、血流紊乱和炎症信号转导等多种因素 共同作用而产生的，但现有的模型却过于简化了这一现实。二维 （2D） 平面培养无法体现细胞间相互作 用，而大多数三维 （3D） 系统又缺乏天然血管所具有的分层结构和血流动力学调控机制。因此，许多基本 机制仍未得到解决，药物试验也常常无法取得预期效果。 2025 年 11 月 11 日，浙江大学 杨华勇 院士团队 周竑钊 、西湖大学 沈璐琦 、杭州师范大学 李琦 作为共同通讯作者，在 Cell 子刊 Cell Biomaterials 上发表了题为： Multiscale bi ...

Core Insights - The rising incidence of cardiovascular diseases (CVD) among young people necessitates the identification of high-risk groups for targeted preventive measures [2][4] - Maternal diabetes is linked to an increased risk of early-onset cardiovascular diseases in male offspring, while female offspring are not affected [11][12] Group 1: Research Findings - A study published by a team from Karolinska Institute confirmed that sons of mothers with type 1 diabetes are at higher risk for early endothelial dysfunction and related cardiovascular diseases, independent of metabolic disorders [2][6][11] - The research utilized a mouse model to demonstrate that maternal hyperglycemia specifically leads to early endothelial dysfunction in male offspring, with oxidative stress and arginase-1 signaling pathways identified as potential mechanisms [6][11] - Epidemiological studies in Denmark and Sweden corroborated these findings, showing that sons of mothers with type 1 diabetes have an increased risk of early cardiovascular diseases associated with endothelial dysfunction [6][8][11] Group 2: Implications - The study highlights a previously underappreciated risk group for early cardiovascular disease, emphasizing the impact of maternal health on offspring cardiovascular health [12] - The findings suggest a need for future preventive strategies targeting this specific demographic, particularly focusing on the health of mothers with diabetes [11][12]

Core Viewpoint - The article highlights the increasing risk of cardiovascular diseases (CVD) during the autumn and winter seasons, particularly among vulnerable populations such as the elderly and those with pre-existing health conditions. It emphasizes the importance of awareness regarding early symptoms and preventive measures to mitigate risks associated with cold weather and lifestyle factors. Group 1: Cardiovascular Disease Statistics - In 2021, CVD was the leading cause of death among urban and rural residents in China, accounting for 48.98% and 47.35% of deaths respectively [3] - The crude incidence rate of CVD among residents aged 18 and above in 2023 was 620.33 per 100,000, with males at 717.36 and females at 519.64, showing a significant increase with age [3] Group 2: Seasonal Impact on Cardiovascular Health - Cold weather poses a direct challenge to blood vessels, leading to constriction and increased blood pressure, which heightens the heart's workload [4] - The autumn and winter seasons coincide with a rise in respiratory infections, which can indirectly harm the cardiovascular system and increase the risk of acute myocardial infarction [6] Group 3: High-Risk Populations - Elderly individuals and young professionals under high stress are identified as high-risk groups for cardiovascular events during the colder months [6][9] - Lifestyle factors such as obesity, hypertension, and sedentary behavior contribute to the increasing prevalence of CVD among younger populations [9] Group 4: Early Symptoms and Misdiagnosis - Common early symptoms of cardiovascular issues include fatigue, chest discomfort, palpitations, and sleep disturbances, which are often overlooked or misdiagnosed as gastrointestinal problems [7] - Patients frequently visit other medical departments without receiving appropriate cardiovascular care, highlighting the need for better awareness and education [8] Group 5: Preventive Measures and Lifestyle Recommendations - Maintaining a healthy lifestyle, including a balanced diet low in salt and high in fruits and vegetables, is crucial for preventing cardiovascular diseases [10] - Regular physical activity, stress management, and adequate sleep are essential components of cardiovascular health [11] - During cold weather, individuals are advised to dress warmly and engage in moderate exercise to adapt to temperature changes [11]

Core Insights - The recent drop in temperatures across the country has led to a significant increase in heart attack patients visiting hospitals, particularly among those with pre-existing cardiovascular conditions [1][2] Group 1: Cardiovascular Disease Risks - Cold weather causes blood vessels to constrict, leading to increased blood pressure and added strain on the heart, which can trigger coronary artery spasms and worsen existing conditions [2] - Symptoms of heart issues can manifest in various forms, including chest pain, dizziness, and discomfort in different body parts, necessitating immediate medical attention [2][3] - The incidence of heart attacks is rising among younger individuals due to lifestyle factors such as obesity, stress, and smoking, highlighting the need for regular blood pressure monitoring and medical guidance [3] Group 2: Stroke Awareness and Prevention - A decrease in temperature by 1 degree Celsius increases the risk of stroke by 1.13%, with winter diets high in calories potentially raising cholesterol and blood lipid levels [4] - Recognizing stroke symptoms is crucial, with immediate treatment within a 4.5-hour window being vital for minimizing brain damage [4] - Establishing emergency protocols in hospitals for stroke treatment is essential, including ensuring airway clearance and timely emergency calls [4] Group 3: Lifestyle Recommendations - Adopting a healthy lifestyle, including proper hydration, balanced diet, and regular exercise, can significantly reduce the risk of stroke [5] - Maintaining good mental health and adequate sleep is important, as stress can contribute to immune issues and blood clot formation [5] - Engaging in consistent physical activity, even at home, can enhance overall cardiovascular health and reduce the likelihood of thrombus formation [5]

时值深秋，昼夜温差大，突发心血管疾病的风险也随之升高。医生提醒，若活动时出现胸闷、胸痛、心 悸、下肢浮肿，以及不明原因的乏力、气短，或者口角歪斜、言语不清等症状，且持续不能缓解，请立 即就医。 医生提醒，冠心病患者在医生的指导下，可使用抗血小板药物预防血栓形成，使用他汀类药物稳定斑 块、降血脂；病情严重的患者需由专科医生评估冠状动脉病变严重程度，改善心脏功能，提升预后效 果。（记者邹欣媛、吴天麟） "高血压、冠心病、心梗、心源性脑梗塞、心衰等都属于心血管疾病的范畴。"宁夏医科大学总医院心内 科主任医师王竟靖说，随着气温下降，血管遇冷容易收缩痉挛，导致血压升高，加重心脏负担。此外， 不及时补充水分、盲目"贴秋膘"以及情绪剧烈波动都可能诱发心血管疾病。 心血管疾病患者以及存在心血管疾病风险因素的人群，需加强防护。医生建议，根据气温变化适时增减 衣物，恶劣天气减少外出，避免头部、颈部、腹部和脚部等部位受寒；注意膳食均衡，坚持少盐、少 油、少糖的饮食习惯；进行适量运动，比如散步、打太极拳，如果室外气温较低，可在室内运动；适量 补充水分，采取少量多次的饮水方式；保持平和、乐观的心态。 "如果既往有血糖、血压、血脂异常， ...

新华社北京10月7日电（余佩璇、张帆）赶工作时手边的冰奶茶、宅家点的重辣火锅配可乐，这些年轻人习以为常的生活场景，正悄悄埋下健康 隐患——越来越多的人在体检时意外发现血压偏高，曾经被贴上"老年人专属病"标签的高血压，如今有逐步向中青年人群蔓延的趋势。中青年 高血压表现特征为何？成因有哪些？该怎样预防或干预？在第28个全国高血压日来临之际，记者采访相关专家进行解答。 "若不加以控制，高血压会造成多系统损伤，其中心脏、脑部、肾脏、眼部及血管危害更为突出。"郑博说，长期高血压会导致动脉硬化、心肌 肥厚，增加心梗、脑卒中风险；肾脏或肾动脉受损可能引发肾功能衰竭；眼底病变可能导致视力下降甚至失明。 专家表示，在中青年阶段干预并改善不良生活方式，有助于控制血压，遏制心血管疾病的发生发展。饮食上，应培养清淡饮食习惯，限制钠盐 摄入，每日食盐量不超过5克。同时，调整饮食结构，应遵循低盐、低脂、高纤维的饮食原则，多吃新鲜蔬菜、水果和全谷类食物，少吃油腻、 高盐、高糖的食物。 作息上，应保证每天7至9小时睡眠，避免周末"补觉式"作息紊乱，防止生物钟失衡。此外，还要根据自身情况选择快走、慢跑、游泳等合适的 运动方式，坚持规律锻炼， ...

央视网消息：9月29日是世界心脏日，国家心血管病中心发布的数据显示，心血管疾病，已成为导 致我国居民死亡的首要原因。现在正是体检季，不少人在自己的体检报告上看到有动脉粥样硬化斑块， 一部分人觉得，这是正常的老化，也有人谈斑块色变，认为是心梗的信号。那么，长了斑块到底要不要 干预？ ...

Core Insights - Cardiovascular diseases are increasingly affecting younger populations, with stress and anxiety identified as significant risk factors for heart health [1][5] - Obstructive Sleep Apnea (OSA) is a rising concern, with an estimated 1.76 billion people in China affected, making it a critical health issue [1][2] - The diagnosis rate of OSA is alarmingly low, with less than 1% in China and only 20% in the U.S., highlighting the need for increased awareness and screening [4] Group 1: Cardiovascular Health - Cardiovascular diseases are the leading cause of death, with a notable increase in cases among younger individuals [1] - Emotional factors, particularly stress and anxiety, are significant contributors to cardiovascular risks in young people [5] - The theme for World Heart Day 2023 is "Rhythm Never Stops," emphasizing the importance of continuous heart health awareness [1] Group 2: Obstructive Sleep Apnea (OSA) - OSA is often misperceived as mere snoring, but it can lead to serious complications such as hypertension, with over 47% of OSA patients in China suffering from high blood pressure [2][4] - The prevalence of OSA is expected to rise, with projections indicating that the number of affected individuals in China could exceed 200 million this year [1] - Diagnosis of OSA typically involves sleep monitoring, which can be conducted in hospitals or at home using portable devices [4]

Company Overview - The founder of Yunnan Yunhaiyao Restaurant Management Co., Ltd., Zhao Han, passed away due to a sudden heart attack at the age of 40, which has garnered widespread attention [5]. - Zhao Han was instrumental in establishing the brand, opening over 100 restaurants in major cities such as Beijing, Shanghai, Guangzhou, and Shenzhen within a decade [5]. Leadership Changes - Following Zhao Han's passing, the company's board underwent adjustments, with Zhu Haiqin taking over as Chairman and CEO, assuming full responsibility for company decisions and management [3]. Industry Context - The restaurant industry has faced numerous challenges in recent years, prompting Yunhaiyao to explore various strategies, including brand collaborations and partnerships with popular media to attract new customers [3].