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Nature子刊:华人学者证实,含糖饮料和人工甜味剂饮料,都与肝病风险增加有关
生物世界· 2025-12-24 10:30
Core Insights - The study published by Yale University reveals a significant association between the consumption of sweetened beverages (both sugary and artificially sweetened) and adverse liver health outcomes, indicating that daily intake of these beverages increases the risk of metabolic dysfunction-related fatty liver disease (MASLD), severe liver disease, and chronic liver disease mortality [2][4]. Group 1: Study Overview - The research utilized data from the UK Biobank, involving 173,840 participants aged 40-69, and applied Cox proportional hazards regression models to analyze the relationship between sweetened beverage consumption and liver health outcomes [3]. - At baseline, 14.2% of participants consumed at least one sugary drink daily, while 10.8% consumed at least one artificially sweetened drink daily, with one serving defined as 250mL [3]. Group 2: Findings on Beverage Consumption - Each additional serving of sugary beverages per day was associated with a 10% increase in MASLD risk, a 21% increase in cirrhosis risk, an 18% increase in severe liver disease risk, and a 37% increase in chronic liver disease mortality risk [4]. - For artificially sweetened beverages, each additional serving per day correlated with a 15% increase in MASLD risk, a 14% increase in severe liver disease risk, and a 41% increase in chronic liver disease mortality risk [4]. Group 3: Health Improvement Potential - Reducing sweetened beverage intake may significantly improve liver health; substituting one serving of sugary drinks with tea or coffee is linked to a 10%-32% reduction in risks associated with MASLD, cirrhosis, severe liver disease, and chronic liver disease mortality [5]. - Similarly, replacing one serving of artificially sweetened beverages with tea or coffee is associated with a 14%-34% reduction in the same health risks [5]. Group 4: Protein Signatures and Health Risks - The study identified specific proteomic signatures associated with sweetened beverage consumption that correlate with increased risks of MASLD, cirrhosis, severe liver disease, and chronic liver disease mortality [5]. - For sugary beverages, each standard deviation increase in related proteomic features was linked to a 65% increase in MASLD risk, a 52% increase in cirrhosis risk, a 111% increase in severe liver disease risk, and a 53% increase in chronic liver disease mortality risk [5]. - For artificially sweetened beverages, the corresponding increases were 96% for MASLD, 71% for cirrhosis, 114% for severe liver disease, and 442% for chronic liver disease mortality [5]. Group 5: Implications for Dietary Recommendations - The findings underscore the importance of understanding how sweetened beverages impact liver health and suggest the need for personalized dietary recommendations to reduce the intake of these beverages to improve liver health and lower the risk of severe complications related to liver disease [6].
天猫国际进博会发布营养保健新趋势,引领科学精准健康消费升级
Sou Hu Cai Jing· 2025-11-08 08:56
Core Insights - The event highlighted the trend of "scientific, precise, professional, and diversified" development in imported healthcare consumption, focusing on oral anti-aging, liver health, and women's health [1][13] Group 1: Trends in Healthcare - Oral anti-aging emerged as a significant focus, with the launch of the "Methylsulfonylmethane + X" anti-aging summit, indicating a shift towards scientific and professional approaches in the industry [2] - The "Tmall International Fourth Meal Liver Fat Reduction Scientific Nutrition White Paper" was initiated to address the needs of nearly 300 million individuals with fatty liver disease in China, emphasizing the scientific mechanisms of key ingredients like fucoxanthin [4] Group 2: Global Brand Participation - The event showcased global brands such as Norway's Aker BioMarine and Japan's Kaneka, highlighting advancements in clinical results and fermentation technology, reflecting a trend from ingredient-focused to technology-driven innovations [6] - Brands like Centrum and Swisse are innovating by offering more refined nutritional solutions that cater to specific age groups and life stages, indicating a shift towards comprehensive lifecycle nutrition management [8] Group 3: Platform Empowerment - Tmall International is enhancing its ecosystem by integrating research, brand collaboration, and consumer engagement, facilitating a seamless path from scientific research to market entry for overseas health brands [11] - The platform's robust cross-border supply chain and AI operational tools enable new health products to enter the Chinese market efficiently, aligning with the "Healthy China 2030" strategy [13]
跨界公益活动呼吁公众关注肝脏健康
Bei Ke Cai Jing· 2025-09-17 10:31
Core Points - The COLOR RUN, known as "the happiest 5K on Earth," recently took place in Beijing with nearly 20,000 participants, promoting health awareness and community engagement [1] - The event was organized in collaboration with the Peking University-Stanford Asian Liver Center, aiming to raise public awareness about liver health and combat stigma associated with hepatitis B [1][3] - The event featured interactive activities, including a "Jade Ribbon" wall for participants to leave colorful handprints and learn about hepatitis B through fun quizzes [1] Health Statistics - According to the World Health Organization (WHO), one person dies from hepatitis-related diseases every 30 seconds, with 80% of infected individuals unaware of their condition [2] - In China, approximately 80 million people are carriers of the hepatitis B virus, equating to 1 in every 14 individuals [2] - China accounts for 31.5% of the global hepatitis B patient population, with about 17 million diagnosed individuals needing antiviral treatment, yet only 3 million currently receiving it [2] Community Engagement - The event attracted various influential organizations and student groups, including the Peking University Love Charity Society, to support the cause and challenge hepatitis B discrimination [1][2] - The center's leader emphasized the importance of promoting liver health through enjoyable activities, aiming to bridge the gap caused by stigma surrounding hepatitis B [3]
护肝意识催生需求 我国肝脏健康市场今年有望突破800亿元
Bei Ke Cai Jing· 2025-06-26 13:57
Core Insights - The report indicates that over 150 million people in China suffer from liver-related issues such as fatty liver and hepatitis, with 80% of early liver damage showing no obvious symptoms [1][2][5] - The rising awareness of health management has led to a diversified demand for health products, particularly liver health products, which are gaining traction among younger consumers [1][2][4] - The liver health market in China is projected to exceed 80 billion yuan this year, positioning it as a star segment within the broader health market [5] Market Trends - The liver health product market has been experiencing rapid growth since 2012, driven by core demands such as metabolism promotion, dietary regulation, and improvement of physical and mental states [4][6] - The demographic of liver health product consumers is shifting, with 35% of consumers in 2023 aged between 26 and 35, making this age group the largest and fastest-growing segment [4][6] Product Offerings - Various forms of liver health products are emerging, including liver tea, liver protection tablets, liver capsules, and health-enhanced gummies, catering to different age groups and health conditions [6] - Natural ingredient-rich liver health products are particularly favored by consumers [4] Sales Channels - Traditional direct sales are declining, with pharmacies, shopping malls, and online platforms becoming the primary purchasing channels, especially e-commerce, which is expected to continue growing due to the younger generation's health consciousness [6][7] - Local brands are achieving significant sales, with some health products surpassing 500 million yuan in annual sales [7]