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数千万融资!国产蛋白组学分析平台完成种子轮
思宇MedTech· 2025-12-15 08:59
近日, 深圳栅极芯致生物科技有限公司(以下简称"栅极芯致") 宣布完成 数千万元种子轮融资 ,由深创投种子基金领投, 南山战新投与光明泰诺种子基金共同投资。 融资将主要用于推进公司 AI 驱动的高通量、超灵敏蛋白组学生物分析平台的研发与产业化,加速仪器与试剂的报证进程,并 进一步扩展在药物开发与临床诊断方向的技术与团队布局。 一、公司 定位 栅极芯致成立于 2023 年,由来自生物芯片材料、半导体工艺、计算光学与生命科学仪器工程领域的专家共同创立。团队具备 显著的跨界特征:既有在微纳结构与材料体系拥有长期积累的科研人才,也有熟悉生命科学仪器商业化路径的工程团队,并 结合了在计算摄影、图像增强、自监督模型等方向具备经验的算法研究者。 公司自创立之初即明确要构建下一代超灵敏蛋白检测平台,核心目标包括: 栅极芯致已围绕核心技术布局数十项专利。公司表示,目前技术已验证可在血液样本中实现飞克级(femtogram)蛋白标志物 检测,在成本、稳定性、集成度及智能化方面具备明确差异化优势。 (1)大视野、高集成度 无需机械扫描即可获得大范围荧光信号,检测能力可随芯片面积线性扩展。 (2)显著降低设备成本与体积 用半导体技术 ...
港股午评|恒生指数早盘跌0.92% 黄金股逆市走高
智通财经网· 2025-12-15 04:07
Market Overview - The Hang Seng Index fell by 0.92%, down 238 points, closing at 25,737 points, while the Hang Seng Tech Index dropped by 1.79% [1] - The trading volume in the Hong Kong stock market reached HKD 108.2 billion in the morning session [1] Gold Sector - Gold stocks rose against the market trend due to increased central bank purchases and growing investment demand, with Zijin Mining International up by 6.94% and Chifeng Jilong Gold Mining up by 3% [1] Resource Sector - Jiexin International Resources surged over 6% as tungsten prices hit a new high, with institutions expecting a continued upward trend across the entire industry chain [2] - Chinese brokerage firms, including Changjiang Securities and Dongwu Securities, announced increases in margin financing limits, leading to a rise in Chinese brokerage stocks, with China Merchants Securities up by 3.77% and Orient Securities up by over 2% [2] Insurance Sector - Domestic insurance stocks continued to rise, with expectations of double-digit growth in new policy premiums and NBV, as New China Life Insurance increased by nearly 4% and China Pacific Insurance rose by 2.6% [2] Sportswear Sector - The sportswear sector saw collective gains, attributed to improved textile and apparel exports in November, with Yue Yuen Industrial up by 6% and Li Ning up by 5% [2] Dairy Sector - Dairy stocks were active as three departments announced stronger measures to boost consumption, with You Ran Dairy up by over 6% and Modern Dairy up by over 5% [2] Technology Sector - Goldwind Technology rose over 4% as the market showed enthusiasm for commercial aerospace concepts, with institutions optimistic about the wind power equipment landscape [3] Pharmaceutical Sector - The pharmaceutical sector faced significant declines, with the Hang Seng Biotechnology Index down by 3.95% and the Hang Seng Innovative Drug Index down by 3.83%, highlighted by a drop of over 8% in Gilead Sciences [4] Optical Communication Sector - The optical communication sector experienced a broad decline, with Yangtze Optical Fibre and Cable falling by over 8% following Oracle's delay in OpenAI data center construction [5] Semiconductor Sector - Concerns over an AI bubble resurfaced, leading to declines in semiconductor stocks, with Hua Hong Semiconductor down by over 6% and SMIC down by over 2% [6]
新型生物芯片助力病毒抗体快速筛查
Xin Hua She· 2025-12-15 03:48
研究人员目前正在进一步优化芯片的稳定性与重复性,希望能将其投入到新型呼吸道病原体的早期检测 中。 新华社耶路撒冷12月14日电(记者王卓伦 路一凡)以色列魏茨曼科学研究所日前发布公报说,该所研 究人员开发出一种无细胞生物芯片,未来可用于新发病毒的早期抗体快速筛查、候选疫苗抗体活性比较 等。 公报说,传统的病毒抗体研究通常需要在实验室里逐步完成病毒蛋白的表达、纯化,再利用酶联免疫吸 附试验等方法分析抗体反应,整个流程耗时较长、步骤复杂。面对快速传播的新发病毒,研究人员常难 以及时开展大规模蛋白筛选和免疫学分析。 这种新型生物芯片基于基因编程,每个生物芯片可携带30至40个特定病毒蛋白或片段。仅需不到一滴 血,就可以揭示一个人在几十个病毒目标或抗原上的免疫"指纹"。由于每种抗原出现在芯片上的不同位 置,研究人员可以分别测量与每种抗原结合的抗体数量。 实验结果显示,与传统的标准酶联免疫吸附试验相比,这种芯片可检测到传统方法无法检测到的更微妙 的抗体反应。 相关成果已发表在英国《自然·纳米技术》杂志上。(完) ...
【IPO追踪】再现“三股齐发” 翰思艾泰获7家基石投资者支持
Sou Hu Cai Jing· 2025-12-15 03:33
12月15日,翰思艾泰-B(03378.HK)、轻松健康(02661.HK)、诺比侃(02635.HK)同日宣布招股。其中,翰思艾泰-B关注度相对较高,原因是此前上市 生物科技股多数取得不错表现。 今年以来,借助第18A章登陆港股市场的创新药企首日表现不俗,宝济药业-B(02659.HK)首日飙涨近139%,旺山旺水-B(02630.HK)、轩竹生物-B (02575.HK)、劲方医药-B(02595.HK)等多股也在首日实现显著上升。 12月以来,港股IPO市场迎来上市小高潮,共有21家企业启动上市或进入招股阶段。截至发稿,这20家企业中,9家已完成上市,2家完成招股并等待挂牌, 9家正处于招股阶段。其中,近两个交易日招股活动尤为密集,6家企业集中招股,连续两日呈现"三箭齐发"的态势。 | 所申請 | 申請/成功 | 所申請 | 申請 / 成功 | 所申請 | 申請/成功 | 所申請 | 申請 / 成功 | | --- | --- | --- | --- | --- | --- | --- | --- | | 香港發售 | 配發時應付 | 香港發售 | 配發時應付 | 香港發售 | 配發時應付 | 香港發售 ...
江苏康为世纪生物科技股份有限公司 关于首次公开发行前股票期权行权限售股上市流通的公告
Core Points - The company will have 434,236 shares listed for circulation on December 22, 2025, as part of its stock option incentive plan [1][2][4] - The total number of shares after the initial public offering (IPO) was 93,161,111, which has since increased to 112,493,716 shares due to stock option exercises and capital increases [2][3] Summary by Sections Listing Details - The type of stock listing is categorized as "other," with a total of 434,236 shares available for subscription through offline methods [1] - The circulation date for the listed shares is set for December 22, 2025 [1] Share Capital Changes - Following the IPO on October 25, 2022, the company had 93,161,111 shares, with 73,115,709 shares under limited circulation and 20,045,402 shares freely tradable [1] - On December 22, 2022, the first exercise of the stock option plan resulted in the issuance of 361,862 shares, raising the total share count to 93,522,973 [2] - A subsequent capital increase on May 16, 2023, led to a further increase in total shares to 112,227,568 [2] - The second exercise of the stock option plan on March 11, 2024, added 266,148 shares, bringing the total to 112,493,716 [3] Lock-up Period and Commitments - The shares being listed are subject to a lock-up period of 36 months from the exercise date, which began on December 22, 2022 [2] - Shareholders involved in the stock option exercise have committed to not reducing their holdings during this period and will adhere to the same reduction regulations as the company's directors and senior management after the lock-up expires [3]
Cell Stem Cell:上海科技大学向阳飞团队建立交感神经节类器官,在体外模拟交感-心脏连接
生物世界· 2025-12-13 04:04
Core Viewpoint - The article discusses a significant advancement in the field of neuroscience, specifically the successful creation of human sympathetic ganglia organoids (hSGO) from human pluripotent stem cells (hPSC), which can be integrated with human heart organoids (hHFO) to form a human sympathetically innervated heart organoid (hSHO) [1][6]. Group 1: Research Background - The sympathetic ganglia are a crucial component of the peripheral nervous system (PNS) and play an essential role in maintaining homeostasis [4]. - Previous attempts to create organoids representing the peripheral nervous system have been limited, particularly in mimicking the self-organizing development of sympathetic ganglia [5]. Group 2: Research Methodology - The research team utilized directed 3D differentiation techniques from human pluripotent stem cells to develop a method for generating human sympathetic ganglia organoids (hSGO), which exhibit directed and self-organizing sympathetic neuronal differentiation [5]. - The hSGO produced sympathetic neurons and glial cells, demonstrating functional development over long-term culture [5]. Group 3: Key Findings - By fusing hSGO with hHFO, the researchers successfully recreated the functional sympathetic innervation of the human heart, resulting in the formation of hSHO [6]. - The hSHO model allows for the evaluation of factors regulating sympathetic innervation of the heart, such as nerve growth factor signaling, and reveals that inter-tissue interactions influence the development of both sympathetic nerves and the heart [6].
巨子生物(02367.HK)12月12日回购1403.64万港元,已连续4日回购
巨子生物回购明细 | 日期 | 回购股数 (万股) | 回购最高价 (港元) | 回购最低价 (港元) | 回购金额 (万港元) | | --- | --- | --- | --- | --- | | 2025.12.12 | 40.00 | 35.220 | 35.000 | 1403.64 | | 2025.12.11 | 40.00 | 35.360 | 34.200 | 1388.76 | | 2025.12.10 | 40.00 | 36.220 | 35.620 | 1438.24 | | 2025.12.09 | 40.00 | 36.180 | 35.720 | 1437.64 | 注:本文系新闻报道,不构成投资建议,股市有风险,投资需谨慎。 (原标题:巨子生物(02367.HK)12月12日回购1403.64万港元,已连续4日回购) 证券时报•数据宝统计,巨子生物在港交所公告显示,12月12日以每股35.000港元至35.220港元的价格回 购40.00万股,回购金额达1403.64万港元。该股当日收盘价35.100港元,上涨2.15%,全天成交额2.51亿 港元。 自12月9日以来公司已连 ...
直击朋友圈“开闸了”欢呼声:新企获备案,赴美上市新周期开启
Sou Hu Cai Jing· 2025-12-12 14:57
金融从业者的朋友圈今晚被"开闸了"三个字刷屏,中国证监会一纸备案通知书,点燃了沉寂大半年的中概股赴美上市热情。 证监会国际合作司向龙电华鑫新能源科技集团发出的境外发行上市备案通知书,允许这家注册资本53亿元的新能源材料企业发行不超过1.415亿普通股,选 择在纳斯达克或纽交所上市。 这则消息迅速在金融圈内传播,引发行业人士的集体欢呼。 | 01 市场信号 | | --- | 02 实际数据 龙电华鑫获得备案,象征着中国公司赴美上市通道的重新激活。 这一消息迅速在金融从业者的社交圈中传播,"开闸了"三个字成为今日行业内的关键词。经过近八个月的相对沉寂,此次备案被市场解读为重要政策信号。 有证券律师透露:"近期赴美上市备案审核节奏明显加快,监管部门对符合条件的企业持更为开放的态度。" 龙电华鑫计划募资约5亿美元,将成为近期较大规模的中概股IPO案例。 与外界感知不同,中企赴美上市的通道从未完全关闭,但规模和结构发生了变化。 2025年上半年,已有36家中国公司在美国成功上市,延续了2024年64家的历史高位。主要集中在新能源、生物科技和消费领域。 面对全球资本市场的复杂环境,越来越多的中国企业开始构建多重上市架构 ...
[12月12日]指数估值数据(A股港股上涨;价值风格回调,风险如何呢;港股指数估值表更新;抽奖福利)
银行螺丝钉· 2025-12-12 13:58
文 | 银行螺丝钉 (转载请注明出处) 今天大盘整体上涨,截止到收盘,还在4.2星。 大中小盘股都上涨,小盘股上涨略多。 现金流等价值风格上涨。 成长风格也整体上涨。 今天收盘后,也是12月份指数调仓的时间。 等下周一看到的估值,也就是指数调仓后的了。 港股今天上涨比A股多一些。 港股科技股领涨。 螺丝钉也汇总了港股指数的估值,供参考。 这也跟A股的风格轮动有关。 1. 最近价值风格出现了一些波动。 A股经常出现成长、价值风格的轮动。 (1)今年三季度是成长风格比较强势。 创业板指,在今年3季度,创下最近10年,最大单季度涨幅。 价值风格三季度也上涨,但涨幅就没有成长风格这么多。 (2)到了10-11月,成长风格短期出现大幅回调。 创业板指从3331点,短期下跌到11月24日的2892点,回调13.2%。 科创50波动更大一些,回调了20%。 同期价值风格没有太大波动。 价值、红利等指数略微下跌;自由现金流指数,在10月初到11月24日,甚至还略微上涨了一些。 (3)到了12月,成长风格短期大幅下跌后,出现了反弹。 只是阶段性,成长和价值风格的表现会有强弱。 这也是A股的特点。 成长风格比较吸引市场眼球,短期 ...
昊海生物科技:黎映彤获委任为联席公司秘书、授权代表及法律程序代理人
Zhi Tong Cai Jing· 2025-12-12 12:30
昊海生物科技(06826)发布公告,赵明璟先生已辞任公司其中一位联席公司秘书;根据香港联交所证券上 市规则第3.05条所规定的公司的授权代表;及根据上市规则第19A.13(2)条及公司条例(香港法例第622章) 第16部所规定的代公司于香港接受法律程序送达文件及通知书的公司的授权代表,自2025年12月12日起 生效。继赵先生辞任后,董事会欣然宣布,黎映彤女士,彼具备上市规则第3.28条所规定的专业资格, 已获委任为联席公司秘书、授权代表及法律程序代理人,自2025年12月12日起生效。田敏女士将继续担 任另一位联席公司秘书。 ...