证券代码：300583 证券简称：赛托生物 山东赛托生物科技股份有限公司 投资者关系活动记录表 编号：DY2025-001 投资者关系活 动类别 □特定对象调研 □分析师会议 □媒体采访 业绩说明会 □新闻发布会 □路演活动 □现场参观 □其他 参与单位名称 及人员姓名 参与公司 2024 年度业绩网上说明会活动的投资者 时间 2025 年 5 月 9 日 15:00-17:00 地点 "价值在线"平台（www.ir-online.cn） 上市公司接待 人员姓名 董事长米奇先生 财务总监李福文先生 董事、副总经理、董事会秘书李璐女士 独立董事康立女士 保荐代表人刘彦先生 投资者关系活 动主要内容介 绍 公司于 2025 年 5 月 9 日 15:00-17:00 在"价值在线"（www.ir- online.cn）举办 2024 年度业绩网上说明会，本次业绩说明会采用网络远 程的方式举行，问答环节主要内容如下： 1、问：过去一年，公司的经营策略是什么？ 回复：尊敬的投资者，您好！过去一年，公司董事会管理层确定的经 营策略主要可以用"稳份额、保现金、推注册、剥资产"十二字概括，在 董事会的领导下，公司在生产端严 ...

Summary of Conference Call Records Industry Overview - The pharmaceutical industry is projected to see a revenue decline of 0.46% in 2024, with net profit attributable to shareholders decreasing by 6.7% and non-recurring net profit declining by approximately 11% [1][4] - In Q1 2025, the fastest-growing sectors include medical services, CXO, and raw materials, while community pharmacies and research services lead in revenue growth [1][4] Key Insights on Specific Sectors Innovative Drug Sector - 23 innovative companies reported a total revenue of 62.8 billion yuan in 2024, reflecting a year-on-year growth of 23.8%, with net profit attributable to shareholders reaching 3.7 billion yuan, significantly outpacing the industry average [1][5] - In Q1 2025, these companies achieved a total revenue of 16.3 billion yuan, marking an 18.7% year-on-year increase, indicating a trend towards profitability [5] Research Services Industry - The research services sector saw a total revenue growth of 6.5% in 2024, although profits declined by 20%-16% [6] - In Q1 2025, total revenue grew by 4.7%, with scale profit increasing by 9% and non-recurring profit rising by 13%, indicating a recovery phase compared to the overall industry decline of 5% [6][7] CXO Industry - The CXO sector experienced a revenue decline in 2024 but rebounded in Q1 2025 with a 13% year-on-year revenue growth and a 23% increase in non-recurring net profit, showcasing strong development potential [8] Chemical Preparations Sector - The chemical preparations industry reported stable revenue in 2024, with a slight increase of 1.2%, and a minimal growth of 0.3% in Q1 2025, indicating a phase of stability [9][10] Raw Materials Sector - The raw materials sector faced a revenue decline of 3.8% in Q1 2025, following a 3.9% decrease in 2024, but non-recurring profit grew by 5%, suggesting that the most challenging phase post-pandemic has passed [10] Medical Devices and Traditional Chinese Medicine - The medical devices industry is projected to grow by 1% in 2024 and 0.3% in Q1 2025, with noticeable profit declines potentially linked to centralized procurement policies [11] - The traditional Chinese medicine sector experienced a 6% revenue decline in Q1 2025 due to high base effects, following a 3.9% decrease in 2024 [11] GLP-1 Receptor Agonists Developments - The development of GLP-1 receptor agonists is trending towards oral formulations and extended half-lives, with multi-target drugs becoming a research focus [3][14] - Notably, the revenue for semaglutide surpassed that of pembrolizumab, indicating strong consumer demand [13] - Companies such as Innovent Biologics, Federated Pharmaceuticals, and Boryung Pharmaceutical are making significant strides in the GLP-1 space [16] Market Performance - The overall pharmaceutical sector saw a 1% increase this week, with a year-to-date rise of 1.2%, slightly underperforming compared to the CSI 300 index, which fell by 1% [2] - Notable individual stock performances included Changshan Pharmaceutical (up 23%), Haichuang Pharmaceutical (up 22%), and Jinkai Biotechnology (up 19%) [2] Conclusion - The pharmaceutical industry is navigating a challenging landscape with mixed performance across sectors, but innovative drugs and specific niches like GLP-1 receptor agonists show promising growth potential. The recovery signs in research services and CXO sectors are noteworthy, indicating potential investment opportunities.

Summary of Key Points from Conference Call Records Industry Overview - The medical device sector is expected to see investment opportunities in Q2 2025 due to steady equipment updates and the end of inventory clearance by companies [1][5] - The pharmaceutical industry is projected to perform relatively flat in 2025, ranking between 10th to 15th among 31 primary industries [2] Key Insights on Specific Sectors Innovative Drugs - The innovative drug sector showed strong performance in Q1 2025, with companies like BeiGene reporting a 50% year-over-year revenue increase, and others like Innovent and Rongchang Biotech seeing growth rates of over 40% and nearly 60%, respectively [3] - Small-cap companies like Aidi Kang experienced triple-digit growth, indicating a robust market for innovative drugs [3] Medical Devices - The medical device market is witnessing a significant uptick in procurement, with a nearly 70% year-over-year increase in bidding for equipment in Q1 2025 [3][17] - Major imaging equipment and radiation therapy devices are in high demand, particularly in tertiary hospitals, with procurement rates accelerating in eastern provinces like Jiangsu and Guangdong [20][22] Traditional Chinese Medicine (TCM) - The TCM sector is expected to perform well in Q2 and Q3 2025, driven by domestic demand expansion, aging population, and state-owned enterprise reforms [1][9] - Key recommended stocks include China Resources Sanjiu, Dong-E E-Jiao, and Jianmin, with valuations currently at 15-17 times earnings [9] Pharmaceutical Retail - The pharmaceutical retail sector is undergoing a supply-side clearance, with leading chains focusing on cost reduction and efficiency to ensure profit growth [11] - Companies like Yifeng Pharmacy and Lao Bai Xing are highlighted for their operational efficiency [11] API Market - The active pharmaceutical ingredient (API) market is stabilizing after years of price declines, with companies like Huahai Pharmaceutical and Tianyu Co. reporting stable revenues around 1.4 billion [12] Future Trends and Events - Upcoming academic conferences and significant data releases from companies are expected to impact market sentiment positively [6] - The medical device sector is projected to see concentrated procurement activity in Q3 and Q4 2025, following a government push for large-scale equipment updates [17][18] Additional Insights - The in-vitro diagnostics (IVD) sector is facing pressure due to price reductions and tax adjustments, but a potential recovery is anticipated by the end of 2025 [8] - The high-value consumables market remains stable, with companies in orthopedics showing strong performance post-collective procurement [8] - The construction of tightly-knit county medical communities is expected to drive procurement in these areas, with a goal of 90% completion by the end of 2025 [23]

Investment Rating - The report maintains a "Buy" rating for multiple companies in the pharmaceutical sector, including Junshi Biosciences, Hualan Biological Engineering, and others [4]. Core Viewpoints - The report highlights the investment opportunities in innovative drugs against the backdrop of global asset rebalancing, particularly focusing on KRAS G12C mutation in non-small cell lung cancer (NSCLC) [2][8]. - It emphasizes the potential for KRAS G12C inhibitors to advance to first-line treatment for NSCLC, with an estimated 30% of KRAS mutations in NSCLC being of the G12C subtype, leading to approximately 30,000 new cases annually in China [5][17]. Summary by Sections 1. Industry Viewpoints and Investment Recommendations - KRAS G12C inhibitors are progressing towards first-line treatment for NSCLC, with current standard therapies being PD1 ± chemotherapy [18]. - The report suggests focusing on innovative drugs, particularly in the context of increased liquidity and risk appetite in the market, with significant data releases expected from major conferences [6][32]. 2. Pharmaceutical Industry Market Performance - The pharmaceutical sector saw a 1.01% increase, slightly underperforming the CSI 300 index by 1.00 percentage points [39]. - Sub-sectors such as drug packaging and medical devices performed well, while innovative drugs lagged behind [39]. 3. Company Dynamics - Notable company activities include the approval of new drugs and clinical trial advancements, such as the successful Phase III trials for AstraZeneca's Breztri and Genmab's Epcoritamab [46]. - Companies like Junshi Biosciences and Innovent Biologics are highlighted for their leading positions in the KRAS G12C inhibitor market [22][23]. 4. Industry Dynamics - The report discusses the impact of patent expirations on raw material demand, projecting a significant increase in sales due to the expiration of patents for top-selling small molecule drugs [35]. - It also notes the improvement in demand for raw materials and the end of inventory destocking phases, suggesting a positive outlook for the raw material sector [35].

Investment Rating - The investment rating for the pharmaceutical and biotechnology industry is "Positive" [2]. Core Insights - The report highlights a marginal easing of tariff policies, suggesting a potential recovery in consumption and export sectors within the industry [3][12]. - The pharmaceutical and biotechnology sector has shown a weekly return of 1.01%, ranking 26th among 31 primary sub-industry indices, with medical devices leading at 1.67% [3][27]. - Recent government policies, such as the establishment of geriatric medicine departments in hospitals and new regulations for drug wholesale management in the Beijing-Tianjin-Hebei region, are expected to positively impact the industry [3][47]. Summary by Sections 1. Industry Overview - The pharmaceutical and biotechnology sector's performance over the past month was a return of 4.77%, ranking 19th among 31 primary sub-industry indices [3][14]. - The sector's current PE (TTM) is 26.29 times, which is below the historical average of 31.15 times, indicating a relatively low valuation [20][21]. 2. Market Performance - The report notes that the recent three-month performance shows a decline of 1.88%, while the six-month performance indicates a drop of 7.71% [15][16]. - The report suggests that the easing of tariff impacts may lead to a valuation recovery in specific sub-sectors such as CXO, raw materials, and medical devices [3][12]. 3. Export Industry Chain - The report recommends focusing on the export industry chain, particularly in the CXO sector, with key companies including WuXi AppTec and others highlighted for potential investment [3][12]. - In the raw materials sector, companies like Junshi Biosciences and others are suggested for attention [3][12]. 4. Consumption Recovery - The report anticipates that monetary policies such as interest rate cuts and reserve requirement ratio reductions will enhance macroeconomic consumption [3][12]. - Specific sectors for investment include ophthalmology and dental care, medical aesthetics, traditional Chinese medicine, and retail pharmacy leaders [3][12]. 5. Industry Dynamics - Recent policy developments include the release of guidelines for geriatric medicine and new regulations for drug wholesale management, which are expected to foster healthy development in the pharmaceutical distribution sector [3][47]. - Notable industry news includes collaborations between major pharmaceutical companies and health platforms, as well as significant investments in local production facilities [47].

Investment Rating - The investment rating for the pharmaceutical and biotechnology industry is "Positive" (maintained) [1] Core Insights - The report emphasizes the focus on innovative drugs and the recovery of consumer demand as key drivers for investment in the pharmaceutical sector [3] - The TCE (T-cell Engager) solid tumor pipeline is highlighted, with Janux and Vir making significant progress in their development plans [5][13] - The pharmaceutical sector saw a 1.01% increase in the second week of May, underperforming the CSI 300 index by 1 percentage point, ranking 26th among 31 sub-industries [6][15] Summary by Sections TCE Solid Tumor Pipeline Update - Janux announced that JANX007 (PSMA/CD3) will enter the 1b expansion trial, targeting taxane-naive patients, marking a significant step for TCE in solid tumors [5][13] - Vir has registered VIR-5525 (EGFR/CD3) for a first-in-human trial, expected to start this month, focusing on EGFR-expressing NSCLC [5][13] Market Performance - In the second week of May, the pharmaceutical sector increased by 1.01%, with the medical device sector showing the highest growth at 1.98% [6][19] - The report notes that the offline pharmacy sector experienced the largest decline, dropping by 1.65% [19] Recommended and Benefiting Stocks - Recommended stocks in the pharmaceutical and biotechnology sector include: - Innovative drugs: Zai Lab, Innovent Biologics, and others [7] - Traditional Chinese medicine: Dong-E E-Jiao, Jiangzhong Pharmaceutical, and others [7] - Medical devices: Mindray Medical, and others [7]

Investment Rating - The investment rating for the pharmaceutical and biotechnology industry is "Positive" (maintained) [1] Core Insights - The report emphasizes the focus on innovative drugs and the recovery of consumer demand as key drivers for investment in the pharmaceutical sector [3] - The TCE (T-cell Engager) solid tumor pipeline is highlighted, with Janux and Vir making significant progress in their development plans [5][13] - The pharmaceutical sector saw a 1.01% increase in the second week of May, underperforming the CSI 300 index by 1 percentage point, ranking 26th among 31 sub-industries [6][15] Summary by Sections TCE Solid Tumor Pipeline Update - Janux announced that JANX007 (PSMA/CD3) will enter the 1b expansion trial, targeting taxane-naive patients, marking a significant step for TCE in frontline indications [5][13] - Vir has registered VIR-5525 (EGFR/CD3) for a first-in-human trial, expected to start this month, focusing on EGFR-expressing NSCLC [5][13] Market Performance - In the second week of May, the pharmaceutical sector increased by 1.01%, with the medical device sector showing the highest growth at 1.98% [6][19] - The report notes that the offline pharmacy sector experienced the largest decline, dropping by 1.65% [19] Recommended and Benefiting Stocks - Recommended stocks in the pharmaceutical and biotechnology sector include: - Innovative drugs: Zai Lab, Innovent Biologics, Kelun-Biotech, Yifan Pharmaceutical, and others [7] - Traditional Chinese medicine: Dong-E E-Jiao, Jiangzhong Pharmaceutical, and others [7] - Medical devices: Mindray, Aohua Endoscopy, and others [7]

Group 1: Industry Overview - The overall revenue growth rate for the pharmaceutical and biotechnology sector in Q1 2025 was -4.8%, with a net profit growth rate of -12.2%[3] - The raw material drug sector showed resilience with a revenue growth rate of -3.6% and a net profit growth rate of 10.5% in Q1 2025, benefiting from demand recovery and price stabilization[3] Group 2: Profitability and Financial Performance - In 2024, major raw material drug companies saw an increase in gross margin and net margin by 0.78 percentage points and 0.39 percentage points respectively, while Q1 2025 saw a decline in average gross margin and net margin by 0.64 percentage points and 1.87 percentage points respectively[5] - The average operating cash flow for major raw material drug companies reached 10.04 billion yuan in 2024, a 14.65% increase from 2023, indicating a positive trend[31] Group 3: Capital Expenditure Trends - Capital expenditure for major raw material drug companies in 2024 totaled 7.242 billion yuan, reflecting a year-over-year decrease of 4.12%[36] - The capital expenditure to depreciation ratio for the raw material drug sector decreased from 1.79 in 2023 to 1.27 in 2024, indicating ongoing capacity reduction and structural adjustments[36] Group 4: Investment Strategy - Investment recommendations focus on selecting raw material drug companies with strong growth attributes and stable competitive landscapes, particularly in bulk and specialty raw materials[44] - Companies like Guobang Pharmaceutical and Tianyu Co., Ltd. are highlighted for their favorable supply dynamics and demand recovery[44] Group 5: Risk Factors - Risks include intensified competition leading to suboptimal recovery in product prices and volumes, production safety incidents, and exchange rate fluctuations impacting profitability[47]

Group 1: Investor Relations Activity Overview - The company held an earnings briefing on May 8, 2025, via the China Securities Roadshow Center [4] - Participants included the company's chairman, vice chairman, and board secretary [4] Group 2: Sales Performance and Market Strategy - In 2024, domestic sales revenue reached 37,235.67 million CNY, accounting for 69.32% of total revenue, while export revenue was 16,477.95 million CNY, making up 30.68% [6] - The company plans to mitigate policy risks by optimizing management, reducing costs, and expanding market reach [6] Group 3: Product Development and Market Impact - The "40 tons of Lopinavir and 60 tons of Rufinamide API construction project" was completed and is expected to positively impact operations once products are marketed [6] - Rufinamide has been registered in over ten European countries, while Lopinavir's domestic registration is under review, with expected approval within the year [6] Group 4: Future Growth Strategy - The company aims to focus on refining APIs, expanding new materials, specializing in intermediates, and developing generic and innovative drugs [7] - Strategies include enhancing product quality to maintain market share and investing in R&D for new API development [7] - The company will implement a "dual circulation" strategy to expand both domestic and international markets [7]

Investment Rating - The report indicates a positive outlook for the pharmaceutical raw materials sector, highlighting a significant profit growth in Q1 and an expected improvement in industry supply and demand dynamics [3][4]. Core Insights - The pharmaceutical raw materials sector experienced a revenue of CNY 1176.77 billion in 2024, a year-on-year increase of 6.74%, with a net profit of CNY 150.46 billion, reflecting a growth of 27.89% [3][4][21]. - In Q1 2025, the sector's revenue was CNY 295.46 billion, a slight decline of 0.48% year-on-year, but net profit increased by 20.87% to CNY 45.62 billion [3][4][21]. - The report emphasizes that the rapid profit growth is attributed to several factors, including a low base in H2 2023, the end of inventory destocking by global downstream manufacturers, and improved product pricing stability [3][4][21][23]. Summary by Sections Q1 Performance - The raw materials sector's revenue was stable year-on-year, with a slight decline in Q1 2025 compared to the previous year, while profits showed significant growth [3][4][21]. - The sector's gross margin improved to 38.14% in Q1 2025, up 1.76 percentage points year-on-year, and the net margin reached 15.41%, an increase of 2.63 percentage points [4][25]. Industry Concentration - The top 10 companies in the raw materials sector contributed over 73% of total revenue in 2024, with significant contributions from companies like New and Cheng and Pro Pharmaceutical [31][33]. - In Q1 2025, the top 10 companies accounted for 73.19% of total revenue, indicating a slight decrease in concentration compared to the previous year [33][34]. Valuation and Construction Projects - The report notes that the valuation of the raw materials sector remains at historical lows, with a PE ratio of 30.26x at the end of 2024 and 33.97x at the end of Q1 2025 [5][42]. - The total construction projects in the sector decreased to CNY 163.57 billion by Q1 2025, reflecting a decline of 4.31% year-on-year, indicating a slowdown in capacity expansion [9][44]. Investment Recommendations - The report suggests focusing on companies with strong performance certainty in the formulation and CDMO sectors, such as Aorite and Pro Pharmaceutical, as well as those with significant new product contributions [10][38]. - It highlights the potential for increased demand for raw materials due to the expiration of patents for top-selling small molecule drugs in the coming years [6][42].