Core Insights - The company reported a revenue of 3.188 billion RMB for the six months ending June 30, 2025, representing a year-on-year growth of 20.08% [1] - Net profit attributable to shareholders was 617 million RMB, an increase of 23.71% year-on-year, with basic earnings per share at 1.68 RMB [1] - The gross profit margin for the first half of 2025 was 43.26%, up by 2.03 percentage points compared to the same period last year [1] Revenue Breakdown - The small molecule CDMO business generated revenue of 2.429 billion RMB, reflecting a year-on-year growth of 12.80% [1] - The emerging business segment achieved revenue of 756 million RMB, marking a significant increase of 51.32% year-on-year [1] Operational Performance - Despite a challenging global biopharmaceutical financing environment, the company demonstrated organic revenue growth and positive trends, highlighting its operational strength and solid global customer base [1] - The net profit growth outpaced revenue growth by 3.63 percentage points, attributed to cost reduction and efficiency improvement measures, as well as increased delivery scale and capacity utilization in emerging businesses [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其 準確性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部份內容 而產生或因倚賴該等內容而引致的任何損失承擔任何責任。 Asymchem Laboratories (Tianjin) Co., Ltd. 凱萊英醫藥集團（天津）股份有限公司 （於中華人民共和國註冊成立的股份有限公司） （股份代號：6821） 海外監管公告 本海外監管公告乃由本公司根據香港聯合交易所有限公司證券上市規則第 13.10B 條作 出。 茲載列本公司在深圳證券交易所網站刊登的以下資料中文全文，僅供參閱。 承董事會命 凱萊英醫藥集團（天津）股份有限公司 Hao Hong博士 董事長、執行董事兼首席執行官 中國天津，二零二五年八月二十五日 於本公告日期，本公司董事會由董事長兼執行董事 Hao Hong 博士，執行董事楊蕊女 士、張達先生及洪亮先生，非執行董事 Ye Song 博士及張婷女士，以及獨立非執行董 事孫雪嬌博士、侯欣一博士及謝維愷先生組成。 【2025 年 8 月 26 日】 凯莱英医药集团（天津）股份有限公司 2025 年半年度报告全文 1 ...

Core Viewpoint - The company reported a significant turnaround in its financial performance for the first half of 2025, achieving a revenue of 1.621 billion yuan, a year-on-year increase of 19.88%, and a net profit of 27.0595 million yuan, compared to a loss of 170 million yuan in the same period last year [1] Group 1: Financial Performance - The company achieved a basic earnings per share of 0.05 yuan [1] - Revenue growth was primarily driven by strong performances in small molecule APIs, gene cell therapy, and new molecular businesses, with respective year-on-year growth rates of approximately 20%, 71%, and 128% [1] - The European market saw a revenue increase of about 35%, while the North American market grew by approximately 33% [1] Group 2: Client and Project Engagement - The company provided small molecule API services to over 320 global clients, acquiring 40 new clients during the reporting period [2] - The gene cell therapy business achieved a reduction in losses, serving 51 clients and signing new orders worth 52.55 million yuan [2] - The new molecular business signed orders worth 41.86 million yuan, providing services for 38 clients across 67 projects [2] Group 3: Market and Operational Insights - The company has a cumulative service record of over 1,300 clients and more than 4,600 successful project deliveries, covering major disease treatment areas such as antiviral, oncology, and rare diseases [3] - The company has optimized its internal operations to effectively respond to challenges in the domestic generic drug CDMO market [2]

Core Viewpoint - Kanglong Chemical achieved significant growth in revenue and non-net profit in the first half of the year, despite a decrease in net profit due to a one-time gain from a previous equity transfer [1][2][4] Financial Performance - In the first half of the year, Kanglong Chemical reported revenue of 6.441 billion yuan, a year-on-year increase of 14.93%, and a non-net profit of 637 million yuan, up 36.66% year-on-year [1] - The company's net profit attributable to shareholders was 701 million yuan, a decrease of 37% year-on-year, primarily due to a large equity transfer gain in the same period last year [1] - Revenue for Q1 and Q2 of this year was 3.099 billion yuan and 3.342 billion yuan, respectively, with non-net profits of 292 million yuan and 345 million yuan, both showing positive growth [1] Historical Context - Kanglong Chemical's average quarterly revenue over the past 22 quarters is approximately 2.4135 billion yuan, with an average non-net profit of about 310 million yuan, indicating current performance is significantly above historical averages [4] - The company has consistently generated over 3 billion yuan in quarterly revenue for four consecutive quarters, suggesting a recovery towards historical best performance [2] Market Position - As of August 22, Kanglong Chemical's A-shares closed at 30.1 yuan per share, with a market capitalization of 53.524 billion yuan, while H-shares closed at 21.68 HKD per share, with a market capitalization of 38.394 billion HKD [5] - The company is one of the leading players in the domestic pharmaceutical outsourcing industry, which has experienced fluctuations in performance over the past five years [5] Business Segments - Kanglong Chemical's main business includes laboratory services, small molecule process development, clinical research services, and large molecule and cell and gene therapy services, with the latter being a focus since 2019 [8] - As of mid-2025, the large molecule and cell and gene therapy segment generated revenue of 211 million yuan, with a year-on-year growth of 0.13%, but a negative gross margin of -54.71% [8] Industry Trends - The domestic pharmaceutical outsourcing industry is showing signs of recovery, with leading companies like WuXi AppTec reporting significant revenue growth [9] - Kanglong Chemical's revenue from North American clients was 4.073 billion yuan, a year-on-year increase of 11.02%, accounting for 63.23% of total revenue [9] - The global pharmaceutical investment landscape is recovering, with projections indicating a rise in investment scale from 71 billion USD in 2023 to 102 billion USD in 2024 [10]

Core Viewpoint - The report from Citi maintains a long-term positive outlook on WuXi AppTec (02268), reiterating an "Outperform" rating and raising the target price from HKD 47.3 to HKD 70.7, reflecting an optimistic growth forecast for the company [1] Financial Performance - WuXi AppTec's revenue and adjusted net profit for the first half of the year increased by 62% and 50% year-on-year, respectively, aligning with previous profit forecasts [1] - The total unfulfilled orders and new signed orders grew by 58% and 48% year-on-year, driven by strong demand in the U.S. market [1] Future Guidance - Management has raised the revenue growth guidance for 2025 from 35% to 45%, primarily due to robust demand for Antibody-Drug Conjugates (ADC) outsourcing and a solid order backlog [1] - Revenue forecasts for 2025 to 2027 have been adjusted upwards by 7% to 8% and net profit forecasts by 13% to 17%, with projected revenue growth of 45%, 31%, and 27% for those years, respectively [1]

Group 1 - The core viewpoint of the report is that WuXi AppTec's revenue and adjusted net profit for the first half of the year increased by 62% and 50% year-on-year, respectively, aligning with previous profit forecasts [1] - The strong demand from the U.S. market has driven a year-on-year growth of 58% in total unfulfilled orders and 48% in new signed orders during the period [1] - Management has raised the revenue growth guidance for 2025 from 35% to 45%, primarily due to robust demand for ADC outsourcing and a solid order backlog [1] Group 2 - The report maintains a long-term positive outlook on WuXi AppTec, reiterating the "Outperform" rating and raising the target price from HKD 47.3 to HKD 70.7 [1] - Revenue forecasts for 2025 to 2027 are projected to grow by 45%, 31%, and 27%, respectively [1]

Core Viewpoint - WuXi AppTec's revenue from the United States is accelerating, with a projected increase in the share of U.S. revenue to over 52% by the first half of 2025 [1] Financial Performance - In the first half of the year, WuXi AppTec's revenue increased by 62.6% year-on-year, reaching 2.701 billion RMB [1]

资料显示，北京昭衍新药研究中心股份有限公司(股票代码:603127.SH/6127.HK),成立于1995年,是专业化 的药物研发服务外包企业(CRO),总部位于北京,在北京、苏州、重庆、广州、无锡、梧州、南宁、云 南、上海、美国加州及波士顿设有子公司,昭衍新药建立有符合国际规范的质量管理体系(CNAS/ILAC- MRA认证),具备中国NMPA、美国FDA、日本PMDA、韩国MFDS及经合组织OECD的GLP资质以及国际 AAALAC(动物福利)认证资质,评价资料满足全球药品注册要求。 *注：AH股是指同时在A股和港股上市的公司，溢价（A/H）越大，说明H股相比A股越便宜。 本文源自：金融界 作者：行情君 8月14日，上证指数跌0.46%，收报3666.44点，恒生指数跌0.37%，收报25519.32点。 XD昭衍新AH溢价达43.47%，位居AH股溢价率第79位。当日收盘，XD昭衍新A股报32.21元，跌幅 5.74%，H股报24.56港元，下跌1.52%。 ...

Core Insights - The CXO (Contract Research Organization and Contract Development and Manufacturing Organization) sector in A-shares shows a mixed performance in the first half of the year, with 19 out of 35 companies reporting a year-on-year profit increase, indicating a positive trend in the industry [1] Group 1: Company Performance - WuXi AppTec leads the CXO companies with a net profit of 5.313 billion yuan, followed by Kelun Pharmaceutical with 1.686 billion yuan, and Tigermed with 1.388 billion yuan [2] - WuXi AppTec's revenue reached 18.871 billion yuan, a year-on-year increase of 6.28%, with a net profit growth of 14.61% [2] - Kelun Pharmaceutical reported a revenue of 4.622 billion yuan, a decline of 8.33%, and a net profit decrease of 3.09% [3] Group 2: Sector Trends - The demand for peptide drugs, traditional Chinese medicine, and ADC (Antibody-Drug Conjugates) is increasing, leading to significant order growth for some CXO companies [4] - WuXi AppTec's TIDES business, focusing on oligonucleotides and peptides, generated 1.33 billion yuan in revenue, a growth of 37.9%, with a backlog of orders increasing by 188% [4] - The CRO service provider Boji Pharmaceutical reported a 49% increase in new business contracts, with traditional Chinese medicine contracts growing by approximately 400% [4] Group 3: Market Expansion - Despite a cooling investment environment in the global pharmaceutical sector, several CXO companies are experiencing growth in overseas markets [5] - Kelun Pharmaceutical's revenue from U.S. clients reached 3.348 billion yuan, with a 44.77% increase when excluding large orders [5] - Tigermed's revenue was 3.711 billion yuan, a year-on-year increase of 3.25%, with a net profit growth of 16.47% [6]

Summary of the Conference Call Records Industry Overview - The CRO (Contract Research Organization) and CDMO (Contract Development and Manufacturing Organization) industries have experienced significant changes over the past decade, driven by increased R&D investment and rising outsourcing rates. It is projected that the outsourcing rate will increase from nearly 50% to 60%-65% by 2030 [1][2][3]. - The domestic CXO companies maintain competitiveness in the global market due to advantages such as an engineer dividend, cost advantages, and policy support [1][5][6]. Key Insights and Arguments - The CDMO industry is entering a commercialization phase, with innovative drug technologies like ADC (Antibody-Drug Conjugates) and peptides driving high growth in niche segments [2][16]. - The CXO sector is currently valued at approximately 32 times earnings for 2025, which is about 30% lower than the average over the past three years. As market expectations improve, profitability is expected to gradually increase, leading to a "Davis Double" effect where valuation and earnings both rise [2][18]. - The industry has faced challenges from geopolitical tensions and the COVID-19 pandemic, but recent easing of these tensions and strong performance from leading companies like WuXi AppTec have contributed to a recovery in orders, with growth rates returning to 20% for CDMO orders [1][4][15]. Important but Overlooked Content - The CXO industry has undergone a cycle of mergers and acquisitions, capacity expansion, and increased demand from downstream clients from 2016 to 2021, which has shaped its current landscape [2][9]. - The impact of the Charles River third-quarter report, which fell short of expectations, led to a market pullback in the CXO sector, highlighting the sensitivity of the industry to performance metrics and external factors [1][13]. - The current investment environment is improving, with a notable increase in investment activity in early 2023, despite previous fluctuations due to macroeconomic factors [15][21]. - The supply-demand dynamics in the industry are showing signs of recovery, with overseas markets recovering better than domestic ones, and a general upward trend in pricing due to supply clearing processes [23]. Recommendations for Key Companies - Companies with a strong focus on overseas revenue, such as WuXi AppTec, Kelun Pharmaceutical, and Kanglongda, are showing significant marginal improvements. Domestic companies like Zhaoyan, Mediso, and Tigermed are also recommended for their strong market positions [24].