Wind数据显示，截至9月30日上午收盘，长春高新涨0.87%，报130.02元/股，最新市值为530亿元。 被称为"东北药茅"的长春高新9月29日向港交所递交H股发行上市申请。 相关业内人士表示，长春高新赴港上市，有助于其深化全球化战略布局，加快国际化进程，增强在境外的融资能力，深入挖掘公司价值，推动公司创新管 线成果持续兑现和国际化布局深入推进，打开新增长空间。 持续加大研发力度 近年来，面对行业发展趋势及公司发展需要，长春高新从技术领域着手打造产品赛道，不断提高研发效能及项目商业转化能力，快速形成创新产品矩阵并 转化为企业实际经营成果。公司积极拓展技术覆盖面，推进全球化布局，推动现有产品技术升级和工艺优化，持续完善多层次的研发管线，不断丰富项目 储备。 招股书显示，自2012年至2024年，长春高新研发费用以30.7%的复合年增长率增长。2022年、2023年、2024年及2025年上半年，公司研发费用分别占总收 入的10.8%、11.8%、16.1%及17.5%。 图片来源：Wind 产品组合日益丰富 长春高新业务覆盖治疗性生物制剂、化学药品、疫苗及中成药。公司是国内少数在上述药物类型均实现研发、生产 ...

被称为"东北药茅"的长春高新9月29日向港交所递交H股发行上市申请。 相关业内人士表示，长春高新赴港上市，有助于其深化全球化战略布局，加快国际化进程，增强在境外的融资能力，深入挖掘公司价值，推动公司创新管 线成果持续兑现和国际化布局深入推进，打开新增长空间。 Wind数据显示，截至9月30日上午收盘，长春高新涨0.87%，报130.02元/股，最新市值为530亿元。 图片来源：Wind 产品组合日益丰富 长春高新业务覆盖治疗性生物制剂、化学药品、疫苗及中成药。公司是国内少数在上述药物类型均实现研发、生产和商业化全产业链能力的制药企业之 一。 持续加大研发力度 近年来，面对行业发展趋势及公司发展需要，长春高新从技术领域着手打造产品赛道，不断提高研发效能及项目商业转化能力，快速形成创新产品矩阵并 转化为企业实际经营成果。公司积极拓展技术覆盖面，推进全球化布局，推动现有产品技术升级和工艺优化，持续完善多层次的研发管线，不断丰富项目 储备。 招股书显示，自2012年至2024年，长春高新研发费用以30.7%的复合年增长率增长。2022年、2023年、2024年及2025年上半年，公司研发费用分别占总收 入的10.8% ...

Core Viewpoint - On September 25, 2023, the stock of Pulaike experienced a decline of 0.73%, with a trading volume of 43.54 million yuan, indicating a relatively stable market performance despite the slight drop [1]. Financing Summary - On the same day, Pulaike had a financing buy-in amount of 3.45 million yuan and a financing repayment of 3.77 million yuan, resulting in a net financing outflow of 321,000 yuan [1]. - As of September 25, the total financing and securities lending balance for Pulaike was 151 million yuan, with the financing balance accounting for 3.22% of the circulating market value, which is above the 50th percentile level over the past year, indicating a high level of financing activity [1]. - In terms of securities lending, Pulaike repaid 5,700 shares and sold 600 shares on September 25, with the selling amount calculated at 8,124 yuan, while the remaining securities lending balance was 14,350 yuan, which is below the 20th percentile level over the past year, indicating a low level of securities lending activity [1]. Company Overview - Pulaike Bioengineering Co., Ltd. was established on June 22, 2002, and listed on May 18, 2015. The company primarily engages in the research, production, sales, and related technology transfer of veterinary biological products, chemical drugs, and traditional veterinary medicine [2]. - The revenue composition of Pulaike includes poultry vaccines and antibodies (41.19%), pig vaccines (32.25%), chemical drugs (21.37%), functional health products (1.79%), pet vaccines (1.38%), and other income sources [2]. - As of June 30, 2023, Pulaike had 18,000 shareholders, an increase of 4.27% from the previous period, with an average of 19,234 circulating shares per person, a decrease of 4.09% [2]. Financial Performance - For the first half of 2025, Pulaike achieved an operating income of 559 million yuan, representing a year-on-year growth of 15.79%, and a net profit attributable to shareholders of 116 million yuan, reflecting a significant year-on-year increase of 57.12% [2]. Dividend Information - Since its A-share listing, Pulaike has distributed a total of 1.057 billion yuan in dividends, with 500 million yuan distributed over the past three years [3]. Institutional Holdings - As of June 30, 2023, the seventh largest circulating shareholder of Pulaike was the Guotai Zhongzheng Livestock Breeding ETF (159865), holding 3.4499 million shares, which is an increase of 141,400 shares compared to the previous period [3].

Core Viewpoint - The stock price of Pulaike has experienced fluctuations, with a year-to-date increase of 8.94% but a recent decline over various trading periods, indicating potential volatility in the market [2]. Company Overview - Pulaike Bioengineering Co., Ltd. is located in Luoyang, Henan Province, established on June 22, 2002, and listed on May 18, 2015. The company primarily engages in the research, production, and sales of veterinary biological products, chemical drugs, and traditional veterinary medicine [2]. - The revenue composition of Pulaike includes: poultry vaccines and antibodies (41.19%), pig vaccines (32.25%), chemical drugs (21.37%), functional health products (1.79%), pet vaccines (1.38%), and other income sources [2]. Financial Performance - For the first half of 2025, Pulaike achieved operating revenue of 559 million yuan, representing a year-on-year growth of 15.79%. The net profit attributable to the parent company was 116 million yuan, reflecting a significant increase of 57.12% [2]. - Since its A-share listing, Pulaike has distributed a total of 1.057 billion yuan in dividends, with 500 million yuan distributed over the past three years [3]. Shareholder Information - As of June 30, 2025, Pulaike had 18,000 shareholders, an increase of 4.27% from the previous period. The average circulating shares per person decreased by 4.09% to 19,234 shares [2]. - Among the top ten circulating shareholders, the Guotai Zhongzheng Livestock Breeding ETF ranks as the seventh largest, holding 3.4499 million shares, an increase of 141,400 shares from the previous period [3].

Group 1 - On September 19, Hanyu Pharmaceutical experienced a decline of 2.74% with a trading volume of 1.232 billion yuan [1] - The financing data on the same day showed a financing purchase amount of 120 million yuan and a financing repayment of 159 million yuan, resulting in a net financing outflow of 38.83 million yuan [1] - As of September 19, the total balance of margin trading for Hanyu Pharmaceutical was 1.473 billion yuan, accounting for 6.91% of its circulating market value, which is above the 80th percentile of the past year [1] Group 2 - As of June 30, the number of shareholders for Hanyu Pharmaceutical reached 63,000, an increase of 9.95% compared to the previous period [2] - The company reported a revenue of 549 million yuan for the first half of 2025, representing a year-on-year growth of 114.86%, and a net profit attributable to shareholders of 145 million yuan, a significant increase of 1504.30% [2] - Since its A-share listing, Hanyu Pharmaceutical has distributed a total of 417 million yuan in dividends, with no dividends paid in the last three years [2]

Company Overview - Pulaike Bioengineering Co., Ltd. is located in Luoyang, Henan Province, established on June 22, 2002, and listed on May 18, 2015. The company primarily engages in the research, production, sales, and related technology transfer of veterinary biological products, chemical drugs, and traditional veterinary medicine [1][2]. Financial Performance - For the first half of 2025, Pulaike achieved operating revenue of 559 million yuan, representing a year-on-year growth of 15.79%. The net profit attributable to the parent company was 116 million yuan, reflecting a significant increase of 57.12% [2]. - Since its A-share listing, Pulaike has distributed a total of 1.057 billion yuan in dividends, with 500 million yuan distributed over the past three years [3]. Stock Performance - As of September 16, Pulaike's stock price decreased by 2.07% to 14.21 yuan per share, with a total market capitalization of 4.918 billion yuan. The stock has seen a year-to-date increase of 14.92%, but has declined by 1.93% over the last five trading days and 6.76% over the last twenty days [1]. - The stock's trading volume on September 16 was 32.122 million yuan, with a turnover rate of 0.65% [1]. Shareholder Information - As of June 30, 2025, Pulaike had 18,000 shareholders, an increase of 4.27% from the previous period. The average circulating shares per person decreased by 4.09% to 19,234 shares [2]. - Among the top ten circulating shareholders, the Guotai Zhongzheng Livestock Breeding ETF (159865) ranked as the seventh largest, holding 3.4499 million shares, an increase of 141,400 shares from the previous period [3]. Business Segments - Pulaike's main business revenue composition includes: poultry vaccines and antibodies (41.19%), pig vaccines (32.25%), chemical drugs (21.37%), functional health products (1.79%), pet vaccines (1.38%), and other income sources [1].

Core Viewpoint - The National Medical Products Administration (NMPA) has officially launched a 30-day review and approval channel for innovative drug clinical trials, aimed at accelerating the drug development process in China [1][3]. Group 1: Overview of the 30-Day Channel - The 30-day channel for clinical trial applications is designed for innovative drugs that meet specific criteria, including traditional Chinese medicine, chemical drugs, and biological products [3][4]. - The introduction of the 30-day channel follows the implementation of a 60-day implied approval system in 2019, which significantly improved the efficiency of clinical trial reviews [3][8]. - The NMPA aims to enhance the speed of clinical trials while maintaining high safety standards, ensuring that the review process does not compromise the quality of drug safety assessments [9][10]. Group 2: Conditions for Eligibility - To qualify for the 30-day channel, drug applications must demonstrate significant clinical value and can include pediatric drugs, rare disease drugs, and traditional Chinese medicine [4][5]. - The channel encourages global synchronized research, requiring that Phase III international multi-center clinical trials be primarily led by Chinese clinical trial institutions [4][5]. - Applicants must commit to initiating clinical trials within 12 weeks of approval, which emphasizes the need for efficient clinical operations [6][8]. Group 3: Impact on the Industry - China's innovative drug development is rapidly advancing, with over 20% of the global pipeline of new drugs currently under research [8]. - In the first half of 2025, the total amount of innovative drug licensing reached nearly $66 billion, reflecting growing international recognition of Chinese innovative drugs [8]. - The NMPA's ongoing reforms in the review and approval system have led to a significant increase in the number of approved innovative drugs, with 43 approvals in the first half of the year, marking a 59% year-on-year increase [8][9].

Company Overview - Pulaike Bioengineering Co., Ltd. is located in Luoyang, Henan Province, established on June 22, 2002, and listed on May 18, 2015. The company primarily engages in the research, production, sales, and related technology transfer of veterinary biological products, chemical drugs, and traditional veterinary medicine [1][2]. Financial Performance - For the first half of 2025, Pulaike achieved operating revenue of 559 million yuan, representing a year-on-year growth of 15.79%. The net profit attributable to the parent company was 116 million yuan, reflecting a significant increase of 57.12% [2]. - Since its A-share listing, Pulaike has distributed a total of 1.057 billion yuan in dividends, with 500 million yuan distributed over the past three years [3]. Stock Performance - As of September 8, Pulaike's stock price increased by 2.01% to 14.74 yuan per share, with a total market capitalization of 5.101 billion yuan. The stock has risen by 19.21% year-to-date, but has seen a decline of 3.41% over the past 20 days [1]. - The stock's trading volume on September 8 was 27.6557 million yuan, with a turnover rate of 0.55% [1]. Shareholder Information - As of June 30, 2025, Pulaike had 18,000 shareholders, an increase of 4.27% from the previous period. The average number of circulating shares per shareholder was 19,234, which decreased by 4.09% [2]. - Among the top ten circulating shareholders, the Guotai Zhongzheng Livestock Breeding ETF ranked as the seventh largest, holding 3.4499 million shares, an increase of 141,400 shares compared to the previous period [3]. Business Segmentation - The company's main revenue sources include poultry vaccines and antibodies (41.19%), pig vaccines (32.25%), chemical drugs (21.37%), functional health products (1.79%), and pet vaccines (1.38%). Other income sources include technology licensing (0.94%) and vaccines for ruminants (0.25%) [1].

Core Viewpoint - Reap Bio has shown a mixed performance in stock price, with a year-to-date increase of 20.43% but a recent decline of 2.11% over the last five trading days [2] Company Overview - Reap Bio, established on August 2, 2001, and listed on September 17, 2010, is located in Tianjin Free Trade Zone and specializes in veterinary biological products, chemical drugs, biological agents, and animal health products [2] - The company's main revenue sources are: poultry biological products (35.04%), formulations and raw materials (33.24%), pet supply chain (20.63%), livestock biological products (6.86%), and others [2] Financial Performance - For the first half of 2025, Reap Bio achieved a revenue of 1.708 billion yuan, representing a year-on-year growth of 55.37%, and a net profit attributable to shareholders of 257 million yuan, up 61.19% [2] - Since its A-share listing, the company has distributed a total of 1.371 billion yuan in dividends, with 462 million yuan in the last three years [3] Shareholder Information - As of June 30, 2025, the number of shareholders stood at 27,000, with an average of 12,406 circulating shares per person [2] - Major shareholders include Hong Kong Central Clearing Limited and Guotai CSI Livestock Breeding ETF, with notable changes in their holdings [3]

Core Viewpoint - Lianhuan Pharmaceutical's stock has experienced significant fluctuations, with a year-to-date increase of 119.12%, but a recent decline in the last five trading days by 5.99% [1][2]. Group 1: Stock Performance - As of September 3, Lianhuan Pharmaceutical's stock price was 21.52 CNY per share, with a market capitalization of 6.143 billion CNY [1]. - The stock has seen a trading volume of 289 million CNY and a turnover rate of 4.61% [1]. - The company has appeared on the "Dragon and Tiger List" nine times this year, with the most recent appearance on August 21, where it recorded a net buy of -44.74 million CNY [1]. Group 2: Financial Performance - For the first half of 2025, Lianhuan Pharmaceutical reported a revenue of 1.285 billion CNY, representing a year-on-year growth of 14.12% [2]. - The net profit attributable to shareholders was -40.03 million CNY, a decrease of 163.65% compared to the previous period [2]. Group 3: Shareholder Information - As of June 30, 2025, the number of shareholders was 30,100, a decrease of 0.72% from the previous period [2]. - The average number of circulating shares per shareholder increased by 0.72% to 9,485 shares [2]. - The company has distributed a total of 343 million CNY in dividends since its A-share listing, with 111 million CNY distributed in the last three years [3].