兴业证券表示，当前板块景气度可持续，"创新+国际化"创新药产业趋势不变，短期调整后创新药板块 弹性进一步提升。当前在投融资数据、订单和业绩层面均看到创新药产业链向好趋势。 受海外流动性预期变化影响，港股市场创新药板块近期波动较大，各类资金跑步入场，恒生医药ETF （159892）已连续9日获得资金申购，基金份额创近期新高。 以上内容与数据，与有连云立场无关，不构成投资建议。据此操作，风险自担。 从宏观环境来看，美联储官员近期释放鸽派信号，提振降息预期。在美联储降息周期中，港股市场有望 迎来流动性层面的持续改善。 ...

Investment Rating - The industry investment rating is "Recommended (Maintain)" [1] Core Views - The innovative drug industry chain continues to show strong performance, with the pharmaceutical and biotechnology sector outperforming the CSI 300 index, rising by 3.29% while the index fell by 1.08% during the week of November 10 to November 14, 2025 [9][10] - The market potential for small nucleic acids is continuously increasing, indicating that it may become a significant technological hotspot in innovative drugs [19][22] - The sentiment in the innovative drug sector has recently declined, but the sustainability of the sector's prosperity is expected to continue, with a focus on "innovation + internationalization" [22][24] Summary by Sections 1. Weekly Pharmaceutical Sector Performance - The pharmaceutical and biotechnology sector has shown a year-to-date increase of 22.99%, outperforming the CSI 300 index by 5.38 percentage points [9] - The sector's valuation as of November 14, 2025, is 30.89 (PE, TTM), with a premium of 129.74% over the CSI 300 index [10] 2. Industry Events/Policy Overview - On November 14, 2025, the National Bureau of Statistics reported a stable economic performance, with industrial production increasing by 4.9% year-on-year [17] - The People's Bank of China reported an increase of 14.97 trillion yuan in RMB loans in the first ten months of 2025 [17] 3. Industry Investment Strategy - The report highlights the active business development (BD) transactions in the innovative drug sector, with significant collaborations and licensing agreements, such as the partnership between Sainty Biotech and Eli Lilly [19] - The report suggests a focus on the recovery of the medical device and traditional Chinese medicine sectors, as well as the ongoing improvement in the innovative drug industry chain [22][28] 4. Recommended Stocks - Recommended stocks include: - **Hengrui Medicine**: Expected to achieve rapid growth in both domestic and international markets [29] - **BeiGene**: Anticipated to achieve comprehensive profitability in 2025, with strong performance in its core products [30] - **Innovent Biologics**: Expected to reach a revenue target of 20 billion yuan by 2027 [31] - **Kanglong Chemical**: Projected to see significant revenue growth driven by its innovative products [32] - **WuXi AppTec**: Anticipated to maintain rapid growth in its core business and increase global production capacity [33]

Core Viewpoint - The Hong Kong innovative drug sector is experiencing a rise, with notable increases in stock prices for companies like 3SBio and BeiGene, which has positively impacted the Hong Kong Innovative Drug Selected ETF [1] Company Performance - BeiGene reported a total revenue of 27.595 billion yuan for the first three quarters of 2025, marking a year-on-year increase of 44.2% [1] - The net profit attributable to the parent company was 1.139 billion yuan, driven by sales growth from self-developed products and licensed products [1] - The company plans to submit a listing application in Japan for marginal zone lymphoma in the first half of 2026, with expectations of obtaining orphan drug designation [1] Market Trends - Despite recent adjustments in the innovative drug sector, there has been a counter-trend influx of funds, with a net inflow of 114 million yuan into the Hong Kong Innovative Drug Selected ETF over the past 20 days [1] - The ETF tracks the Hang Seng Hong Kong Stock Connect Innovative Drug Selected Index, focusing on leading innovative drug companies and those with high R&D attributes, suitable for aggressive investment strategies [1] Industry Outlook - According to Industrial Securities, the sentiment in the innovative drug sector has recently declined, but the sustainability of the sector's prosperity remains intact due to ongoing business development [1] - The trend of "innovation + internationalization" in the innovative drug industry is expected to continue, with improved fundamentals observed in the industry chain [1] - Positive trends are noted in investment and financing data, orders, and performance metrics within the sector [1]

Group 1 - The Hong Kong innovative drug sector experienced a strong rally, with the Hong Kong medical ETF (159718.SZ) rising by 1.04% and net subscriptions of 3 million units during the day [1] - Notable stocks such as Jinxin Fertility (01951) increased by 5.51%, Weimaitong (02192) by 5.13%, and Shenwei Pharmaceutical (02877) by 4.45% [1] - The negotiation for the 2025 National Basic Medical Insurance Drug List and the price negotiation for commercial insurance innovative drug list was completed, with 120 domestic and foreign companies participating [1] Group 2 - The innovative drug sector sentiment has recently declined, but with ongoing business development (BD) activities, the sector's sustainability is expected to continue [2] - The current investment and financing data, orders, and performance metrics show a positive trend in the innovative drug industry chain [2] - The Hong Kong medical ETF includes a balanced composition of innovative drugs, CXO, internet healthcare, and innovative devices, making it a convenient tool for investors [2]

Core Viewpoint - The Hong Kong innovative drug sector is experiencing a strong performance, with the Hang Seng Innovative Drug Index rising by 1% as of 14:26, indicating positive market sentiment towards Chinese innovative pharmaceutical companies [1] Group 1: Market Performance - The Hang Seng Innovative Drug Index saw a rise of 1%, with notable gains from stocks such as Cloudtop New Drug rising over 5%, and Zai Lab and Four Rings Pharma both increasing over 3% [1] - The Hang Seng Innovative Drug ETF (159316) recorded a net subscription of over 120 million units during the trading session, reflecting strong investor interest [1] Group 2: Industry Developments - At the 2025 European Society for Medical Oncology (ESMO) annual meeting, Chinese innovative drug companies contributed over 440 abstracts, with 32 studies included in the latest breakthrough abstracts, showcasing their research capabilities across multiple cancer types [1] - According to Industrial Securities, the innovative drug sector's favorable conditions are expected to persist, with the "innovation + internationalization" trend remaining a core focus of the pharmaceutical industry [1] Group 3: Investment Opportunities - The innovative drug industry is anticipated to continue receiving policy support, enhancing the global competitiveness of Chinese innovative drugs and ensuring ongoing commercial profitability [1] - The Hang Seng Innovative Drug Index has been designed to exclude CXO, making it the first "pure" innovative drug index with 100% purity, accurately reflecting the overall performance of Chinese innovative drug companies [1] - The Hang Seng Innovative Drug ETF (159316) is currently the only product tracking this index in the market, providing investors with a streamlined way to capitalize on opportunities in the innovative drug sector [1]

Group 1 - The Hong Kong innovative drug sector has rebounded strongly for the second consecutive day, with notable stock increases for companies such as 3SBio (+7.76%), InnoCare Pharma (+6.88%), and CanSino Biologics (+6.72%) [1] - The upcoming European Society for Medical Oncology (ESMO) annual meeting from October 17 to 21 in Berlin is expected to be a catalyst for domestic innovative drug companies, including CanSino Biologics, Kelun-Biotech, and others [1] - The market is also focused on the third-quarter earnings reports, with a significant trend of new product launches and accelerating revenue for traditional pharmaceutical companies like Hengrui Medicine and BeiGene [1] Group 2 - The Hang Seng Medical ETF (159892) has seen a net inflow of 420 million yuan over the past four days, indicating strong investor interest [1] - The innovative drug industry is expected to maintain its core direction of "innovation + internationalization," with ongoing policy support and enhanced global competitiveness [1] - The Hong Kong Medical ETF (520510) has a leading concentration of CXO stocks, including WuXi AppTec, MicroPort Medical, and JD Health, reflecting a strong focus on AI in healthcare [2]

Group 1 - The medical innovation ETF (516820.SH) experienced a strong increase of 0.98%, with constituent stocks such as BaiLi Tianheng (688506) rising by 3.87%, HengRui Medicine (600276) by 3.38%, and XinChuang (300832) by 2.87% [1] - HengRui Medicine has reached an agreement with Glenmark Specialty, granting Glenmark exclusive rights to develop and commercialize the drug Rukang Trastuzumab in all global regions except for China, Hong Kong, Macau, Taiwan, the USA, Canada, and Europe [1] - The innovative drug sector is expected to maintain its favorable outlook, with continuous policy support and enhanced global competitiveness for Chinese innovative drugs, leading to sustained commercial profitability [1] Group 2 - Institutions remain confident in high-quality innovation and the innovation industry chain, viewing any short-term disturbances as buying opportunities, especially with the anticipated increase in US interest rates which will enhance global liquidity and the trend of technology stocks [2] - Investors who missed the initial rally in the pharmaceutical sector can consider the medical innovation ETF (516820) as a means to capitalize on the rebound of core pharmaceutical assets [2]

Group 1 - The overnight SPDR S&P Biotech ETF (XBI) rose by 3.1%, while the Hong Kong pharmaceutical sector (159718.SZ) opened high but continued to weaken, currently down by 0.93% [1] - Among the constituent stocks, Haijia Medical (06078) led the gains with an increase of 7.41%, while Innovent Biologics (01801) saw the largest decline at 6.57% [1] - Industrial insights suggest that the innovative drug sector's prosperity is sustainable, with a focus on "innovation + internationalization" as the core direction of the pharmaceutical sector [1] Group 2 - The innovative drug industry is expected to continue receiving policy support, enhancing the global competitiveness of Chinese innovative drugs and realizing commercial profitability [1] - There is an improvement in the fundamentals of the innovative drug supply chain, with overseas orders and performance beginning to recover, and domestic business showing a self-controllable logic [1] - The demand in the domestic market is anticipated to recover by 2025, with potential improvements in the consumption medical field and medical devices [1] Group 3 - Institutions remain confident in high-quality innovation and the innovative industry chain, viewing any external disturbances as buying opportunities [2] - The Hong Kong pharmaceutical ETF is well-balanced, including innovative drugs, CXO, internet healthcare, and innovative devices, serving as a convenient standardized tool for investors [2] - Recommendations are made to pay attention to the Hong Kong pharmaceutical ETF (159718.SZ) and its connected funds (Class A: 019598, Class C: 019599) [2]

Group 1 - The National Medical Products Administration of China approved 210 innovative drugs during the "14th Five-Year Plan" period, indicating a sustained growth trend in the sector [1] - In the first seven months of this year, 50 innovative drugs were approved, surpassing the total of 48 approved in the entire previous year [1] - The current landscape of China's innovative drugs has transitioned from quantitative to qualitative changes, with leading trends in new targets, technologies, and diseases [1] Group 2 - Chinese innovative drug assets are experiencing a wave of international expansion, with significant recognition of their value globally [2] - The upfront payments and total transaction values for Chinese innovative drug assets have rapidly increased from $8.7 billion and $99.4 billion in 2020 to $49.4 billion and $561.2 billion in 2024 [2] - In the first half of 2025, the total transaction value reached $635.5 billion, exceeding the total for 2024 and accounting for approximately 40% of the global license-out transaction total [2]

Core Viewpoint - The Hong Kong stock market for innovative drugs continues to rise, with the Hong Kong Stock Connect Innovative Drug ETF (520880) increasing by 3.24%, marking three consecutive days of gains [1]. Group 1: Market Performance - The Hong Kong Stock Connect Innovative Drug ETF (520880) has shown a remarkable year-to-date increase of 115.29%, leading the performance among various innovative drug indices [3]. - Major innovative drug companies such as BeiGene and Innovent Biologics have seen significant stock price increases, with BeiGene rising nearly 5% and Innovent Biologics over 3% [4]. Group 2: Policy and Industry Trends - On August 28, the National Healthcare Security Administration announced the preliminary review of the 2025 medical insurance and commercial insurance innovative drug directory, which includes new drugs and notable CAR-T products [2]. - The innovative drug sector is transitioning from capital-driven growth to profit-driven growth, with a positive trend in profitability across the industry [6]. Group 3: Index Adjustments - The Hang Seng Index has announced a revision to the Hang Seng Stock Connect Innovative Drug Select Index, removing companies primarily engaged in CXO services to focus on innovative drug research and development firms [8][9]. - This adjustment is expected to enhance the index's performance by eliminating disturbances from CXO companies, reflecting the maturation of China's innovative drug development [9].