点击注册小程序 查看完整报告 特别申明： 本订阅号中所涉及的证券研究信息由光大证券研究所编写，仅面向光大证券专业投资者客 户，用作新媒体形势下研究信息和研究观点的沟通交流。非光大证券专业投资者客户，请勿 订阅、接收或使用本订阅号中的任何信息。本订阅号难以设置访问权限，若给您造成不便， 敬请谅解。光大证券研究所不会因关注、收到或阅读本订阅号推送内容而视相关人员为光大 证券的客户。 报告摘要 血制品业务稳健增长，四价流感疫苗接种需求显著增强 截至2025年中报，公司下属单采血浆站数量为34家（含6家分站）；2024年，公司采浆量超过100吨的单采 血浆站有4个，成熟期浆站的年平均采浆量均在国内前列。随着新开浆站采浆量的提升，血浆综合利用率 的提高，公司血制品业务有望保持稳健增长。疫苗板块，随着10月以来民众接种流感疫苗意识显著增强， 各地疾控中心的需求显著增加，公司流感疫苗特别是四价流感病毒裂解疫苗的库存消化较快，公司为此增 加了多个批次四价流感疫苗的批签发申请，预计近期将投放市场。 大力布局创新，参股基因公司进入收获期 公司在血制品领域进行现有产品的工艺升级和新产品开发之外，亦加大疫苗、创新药和生物类似药物的研 ...

Traditional Chinese Medicine - The short-term pressure on the industry base is expected to gradually ease, with channel adjustments accelerating and a recovery in demand anticipated by year-end, leading to improvements for most companies on a low base [1] - The current valuation of the sector is at a low level, with institutional holdings being low, indicating potential for valuation improvement as the fundamentals of the traditional Chinese medicine industry continue to improve [1] - Long-term transformation is underway, with companies actively transitioning towards biopharmaceuticals and chemical drug innovation to create a second growth curve, and the consumer goods nature of traditional Chinese medicine companies offers significant brand extension opportunities [1] Blood Products - The supply side is expected to see an increase in the number of plasma stations as local "14th Five-Year" plans are implemented, with ongoing industry consolidation and mergers anticipated [2] - On the demand side, while the short-term price of albumin is under pressure, there is significant growth potential for demand in immunoglobulin and factor products, with ongoing research and development of new products [2] - The variety of blood products is expected to increase, which will drive profit margins from plasma extraction [2] Vaccines - The industry is facing ongoing operational pressures, but there is optimism for improved sales and contributions from new products [3] - Recent policies related to commercial insurance, medical prevention integration, and industry mergers provide a solid foundation for future development in the vaccine sector [3] - The expansion of vaccine companies into international markets is accelerating, with expectations for progress in overseas market development [3] Pharmaceutical Retail - The industry is showing clear signs of marginal improvement, with better funding conditions and sustained demand for four categories of drugs, leading to expected same-store sales growth [4] - The sector's valuation is at historical lows, with low institutional holdings, and there is anticipation for demand recovery due to respiratory diseases and increased industry concentration [4] - Long-term transformation is being actively pursued by leading pharmacies, with pilot projects expected to yield incremental contributions and valuation recovery by 2026 [4] Pharmaceutical Distribution - The growth of medical insurance expenditures is stable, providing long-term market momentum [5] - The high entry barriers for new players indicate potential for increased industry concentration [5] - Innovative business models are accelerating growth and contributing additional revenue [5] State-Owned Enterprise Reform - The policy framework for state-owned enterprise reform has matured, with clear reform directions and ongoing implementation of market value management and merger policies [6] - The ongoing "14th Five-Year" plan is expected to improve the operations and valuations of related enterprises [6]

Core Viewpoint - The company is actively expanding its international market presence and enhancing its product offerings while addressing pricing strategies and production efficiency to meet annual targets [1][2]. Group 1: International Expansion and Product Development - The company has established an International Cooperation Department to focus on international market development and registration preparations, successfully exporting several immunoglobulin products [1]. - The company is advancing its key products towards international certification and registration, aiming to become a globally influential blood product enterprise [1]. Group 2: Pricing Strategy and Market Position - In response to investor concerns about declining gross margins due to falling prices of blood products, the management indicated that product prices have stabilized in 2025, although there was a decrease compared to the full year of 2024 [1]. - The company plans to implement multiple measures to achieve its annual goals, including increasing market share, boosting sales, and reducing inventory [1]. Group 3: Research and Development Progress - The company maintains a leading level of R&D investment in the industry, with over ten products under research, including blood products and gene-recombinant products [2]. - Two products have completed Phase III clinical trials and have submitted applications for marketing authorization, while others are progressing well in clinical trials [2]. Group 4: Production Capacity and Facility Development - The Yunnan project has completed key product registration inspections and is currently addressing inspection deficiencies, with plans to accelerate production site transfer for major products [2]. - The Yunnan facility is expected to commence production in 2026, focusing on human albumin, intravenous immunoglobulin, and prothrombin complex products [2].

Core Viewpoint - The company reported a revenue of 3.11 billion yuan in the first half of 2025, representing a year-on-year growth of 9.47%, while the net profit attributable to shareholders decreased by 12.88% to 633 million yuan [1] Group 1: Financial Performance - In Q2 2025, the company achieved a revenue of 1.793 billion yuan, with a year-on-year growth of 10.70%, but the net profit attributable to shareholders fell by 5.13% to 388 million yuan [1] - For H1 2025, the company’s plasma collection volume was approximately 1361 tons, a year-on-year increase of 0.7%, holding about 20% of the domestic market share [2] - The revenue from immunoglobulin (IVIG) reached 1.43 billion yuan in H1 2025, up 6.56% year-on-year, with a gross margin of 49.8%, down 7.67 percentage points [2] - Albumin revenue was 1.35 billion yuan, showing a year-on-year increase of 20.8%, with a gross margin of 41.0%, down 11.61 percentage points [2] - Other blood products generated 330 million yuan in revenue, down 13.2% year-on-year, with a gross margin of 43.3%, a decrease of 14.8 percentage points [2] Group 2: Market Position and Growth Potential - The company maintains a leading position in the domestic plasma collection industry, with 107 plasma collection stations, of which 85 are operational as of H1 2025 [2] - The company is expected to achieve significant results in acquiring new plasma collection stations due to the strength of its controlling shareholder, China National Pharmaceutical Group [2] - The launch of the fourth-generation chromatography immunoglobulin (10%) is anticipated to enhance profit margins, as it is safer and more efficient compared to the third generation [3] - The company has several products in the pipeline, including subcutaneous immunoglobulin and recombinant coagulation factors, which are in various stages of clinical trials [3] Group 3: Profit Forecast - The company’s projected net profits for 2025-2027 are 1.44 billion, 1.67 billion, and 1.91 billion yuan, with year-on-year growth rates of -6.8%, 15.5%, and 14.4% respectively [3] - The current price-to-earnings ratios are estimated to be 28, 24, and 21 times for the years 2025, 2026, and 2027 [3] Group 4: Investment Rating - The company maintains a "Buy" rating [4]

Core Viewpoint - The company has made significant progress in its operations, including the transfer of equity stakes, approval for new facilities, and advancements in clinical trials and smart factory construction. Group 1: Financial and Shareholder Information - The company plans to distribute a cash dividend of 1.50 yuan per 10 shares to all shareholders, based on a total of 504,248,738 shares [1] - There has been no change in the controlling shareholder or actual controller during the reporting period [1] Group 2: Major Corporate Actions - The company has approved the public transfer of 80% equity in Jiangxi Boya Xinha Pharmaceutical Co., Ltd., with a revised listing price of 158.1655 million yuan [3][4] - The company received approval to establish a single plasma collection station in Dalat Qi, Inner Mongolia [5] - The company obtained clinical trial approval for subcutaneous immunoglobulin and a supplementary drug application for intravenous immunoglobulin [6] Group 3: Operational Developments - The construction of the blood product smart factory is progressing well, with the main structure completed and various installations underway [6] - The company aims to set high standards for the smart factory project, positioning it as a benchmark in the biopharmaceutical industry [6] Group 4: Shareholder Actions - The controlling shareholder, China Resources Pharmaceutical Holdings Co., Ltd., has completed a share buyback plan, acquiring a total of 6,050,900 shares, representing 1.2% of the total share capital [7][8]

Group 1 - The company has not launched any new products so far this year [2] - Two new products, "subcutaneous injection of human immunoglobulin" and "recombinant human coagulation factor VIIa for injection," have completed clinical trials and submitted for market approval [2]

Group 1 - The company TianTan Bio (600161.SH) has completed clinical trials for its subcutaneous human immunoglobulin product and plans to submit a marketing authorization application by December 2024 [2] - The product features a protein concentration increased to 20% and utilizes a sugar-free amino acid formulation, transitioning the administration route from intravenous to subcutaneous injection, which offers more effective, comfortable, convenient, and economical treatment options [2] - Upon approval, the product is expected to provide patients with a new treatment choice, enhancing the company's product portfolio [2]

Group 1 - The core point of the article is that TianTan Biological (600161.SH) announced that its subsidiary Chengdu Rongsheng received a GMP compliance inspection notice from the Sichuan Provincial Drug Administration [1] - The inspection covered the production workshop and related areas for blood products (subcutaneous human immunoglobulin) [1] - Chengdu Rongsheng's blood product production workshop meets national GMP requirements and can commence production after obtaining the relevant registration certificate and production license [1] Group 2 - The product has completed Phase III clinical trials and a marketing authorization application has been submitted [1] - Future production may be influenced by various factors, indicating uncertainty [1]

Core Viewpoint - The company is preparing for its 2024 annual shareholders' meeting, emphasizing the protection of shareholders' rights and the efficiency of the meeting process [1][2][3]. Meeting Procedures - The board of directors is committed to maintaining order and efficiency during the shareholders' meeting, adhering to relevant laws and regulations [1]. - Shareholders must register according to the meeting notice and present valid identification to attend [1]. - Late arrivals will not be counted in the voting unless approved by the meeting's working group [1]. - Shareholders have the right to speak, consult, and vote during the meeting, and must respect the rights of other shareholders [1][2]. Meeting Agenda - The meeting will cover several key topics, including the review of the 2024 board and supervisory reports, financial statements, and profit distribution plans [3][4]. - The company achieved a revenue of 6.03 billion yuan in 2024, a year-on-year increase of 16.44%, and a net profit of 1.55 billion yuan, up 39.58% [4]. Operational Highlights - The company has focused on enhancing blood source development, achieving a collection of 2,781 tons of plasma in 2024, a 15.15% increase year-on-year [4][5]. - The company has implemented various quality management systems to ensure the safety of plasma donors and the quality of raw plasma [5][6]. - The production of blood products has been optimized through the adoption of advanced information systems, leading to improved efficiency and product yield [5][6]. Research and Development - The company has made significant progress in drug development, with several products completing clinical trials and receiving regulatory approvals [7]. - In 2024, the company was granted 22 patents, including 3 invention patents [7]. Market Strategy - The company is actively expanding its market presence, focusing on pediatric, neurological, and critical care sectors, and has established connections with over 700 top-tier hospitals across more than 30 provinces [8]. - The company is also pursuing international market opportunities, with products registered for sale in Macau and participation in international trade exhibitions [8]. Investment and Growth - The company completed the acquisition of a 100% stake in Zhongyuan Ruide for 185 million USD, adding new plasma collection stations and increasing plasma collection capacity [9][10]. - Ongoing investments in existing plasma stations are aimed at expanding blood source capabilities [10]. Compliance and Governance - The company has established a robust internal control system to ensure compliance with legal and regulatory requirements, enhancing risk management capabilities [10][11]. - The board of directors and supervisory committee have conducted regular meetings to oversee the company's operations and ensure adherence to governance standards [12][19]. Future Plans - The company aims to strengthen budget control, enhance blood source management, optimize production processes, and expand international operations in 2025 [15][16][17].

Group 1: Company Developments - Boya Bio's announcement to transfer 80% stake in its subsidiary, Jiangxi Boya Xinhao Pharmaceutical, for approximately 213 million yuan, aiming to optimize business structure and focus on core development [1] - Heng Rui Pharmaceutical received clinical trial approval for two drugs, HRS-9190 and SHR-3792, with total R&D investments of approximately 6.26 million yuan and 32.71 million yuan respectively, enhancing market confidence in future performance [2] - Boya Bio's approval for clinical trials of subcutaneous immunoglobulin, which is expected to boost R&D activity and provide new profit growth points in the blood products sector [3] - Novartis plans to invest 23 billion USD over the next five years in U.S. infrastructure to ensure local production of key drugs, reflecting confidence in long-term sales growth and core profit margin targets [4] - Argenx's FDA approval of Efgartigimod pre-filled subcutaneous injection for treating specific autoimmune diseases, enhancing market opportunities for Zai Lab through collaboration [5] Group 2: Market Implications - The stake transfer by Boya Bio is expected to generate cash flow and enhance sustainable development, aligning with the company's strategic goals [1] - The clinical trial approvals for Heng Rui's drugs are likely to attract more investors and improve the company's market valuation [2] - The approval of subcutaneous immunoglobulin by Boya Bio is anticipated to strengthen its competitive position in the blood products market [3] - Novartis's investment strategy aims to mitigate tariff risks and ensure supply chain stability, which is crucial in the current uncertain regulatory environment [4] - The approval of Efgartigimod's new formulation is expected to enhance patient convenience and solidify Argenx's leadership in the FcRn antagonist market [5]