证券研究报告：计算机|点评报告 行业投资评级 强于大市|维持 行业基本情况 ⚫ 复盘 3 年 25 倍的 PLTR，我们认为好的 AI 应用赛道应当 具备以下特征 | 收盘点位 | 5947.69 | | --- | --- | | 52 周最高 | 6063.95 | | 52 周最低 | 4080.58 | 近期研究报告 《国产 AI 或将全面超越》 - 2026.01.12 AI for Science，重在 AI+制药赛道 行业相对指数表现（相对值） -6% -1% 4% 9% 14% 19% 24% 29% 34% 39% 2025-01 2025-03 2025-06 2025-08 2025-10 2026-01 计算机 沪深300 资料来源：聚源，中邮证券研究所 研究所 分析师:陈涵泊 SAC 登记编号:S1340525080001 Email:chenhanbo@cnpsec.com 分析师:李佩京 SAC 登记编号:S1340525080003 Email:lipeijing@cnpsec.com 分析师:王思 SAC 登记编号:S1340525080002 Email:wangsi1@c ...

Core Insights - The company focuses on the integration of physical computing, AI, and robotics in early drug research, with a strong foundation in physical algorithms and high-precision force fields [1] - Revenue growth is significant and stable, with projections showing a substantial increase from 1.3 billion RMB in 2022 to 5.2 billion RMB in the first half of 2025, reflecting year-on-year growth rates of 112.3%, 30.8%, 52.8%, and 403.8% respectively [1] - The company has established a partnership with Dove Tree, securing a collaboration worth 59.9 billion USD, with an initial payment of 51 million USD [1] Group 1 - The company has a strong technological migration capability, expanding from drug discovery to AI for science (AI4S), with a potential market space of nearly 50 billion USD in drug research and materials development [2] - The company has demonstrated its ability to accelerate innovation in drug development through AI, enhancing efficiency in key research stages [2] - The company possesses both dry and wet laboratory capabilities, achieving significant milestones in collaboration with Dove Tree and advancing multiple pipelines [3] Group 2 - The company has successfully developed AI models for predicting synthetic feasibility and reaction conditions, pushing the boundaries of frontier chemical reactions [3] - The company has acquired Liverpool ChiroChem (LLC), which boasts a leading global chiral molecule experimental library [3] - The target market capitalization is set at 48.7 billion RMB, with a "buy" rating assigned based on projected revenue growth from 7.95 billion RMB in 2025 to 14.21 billion RMB in 2027 [3]

Investment Rating - The report initiates coverage with a "Buy" rating for the company, targeting a market value of 48.7 billion RMB [6][5]. Core Insights - The company is positioned as a leader in AI4S (Artificial Intelligence for Science), with significant growth potential in drug discovery and new materials [5][51]. - Revenue is expected to grow substantially, with projections of 795 million RMB in 2025, representing a year-on-year increase of 198% [6][5]. - The company has established a strong partnership with DoveTree, securing a strategic collaboration worth 5.99 billion USD, which includes an upfront payment of 51 million USD [7][5]. Financial Data and Profit Forecast - Revenue for the years 2023 to 2025 is projected to be 174 million RMB, 266 million RMB, and 795 million RMB, with corresponding growth rates of 30.8%, 52.75%, and 198.39% [4][6]. - The adjusted net profit is forecasted to transition from a loss of 522 million RMB in 2023 to a profit of 309 million RMB by 2027, indicating a significant turnaround [4][6]. - The company’s price-to-sales (PS) ratios for 2025 to 2027 are estimated at 47x, 38x, and 26x, respectively, with a target PS of 49x for 2026 [6][5]. Business Model and Technological Edge - The company utilizes a comprehensive approach combining quantum physics, AI, and robotics to enhance drug discovery processes, covering the entire lifecycle from drug design to clinical trials [23][5]. - The core technology includes high-precision virtual data generation through quantum physics, which addresses data scarcity in AI drug research [23][5]. - The company has a unique capability to integrate both dry and wet lab experiments, enhancing research efficiency and data accumulation for model optimization [5][51]. Market Position and Competitive Advantage - The company is recognized for its strong technical capabilities and has a competitive edge in the AI pharmaceutical sector, with a focus on both drug discovery and new materials [5][51]. - The market for AI4S is projected to reach nearly 50 billion USD, highlighting the expansive potential for the company's technology in both pharmaceutical and materials research [5][51]. - The report emphasizes the strong migration potential of the underlying technology from drug discovery to new materials, leveraging similar physical principles [51][5].

Core Viewpoint - The report from Shenwan Hongyuan highlights that Jingtai Holdings (02228) has established a complete closed loop for early drug research and development through its core technologies of "physical computing + AI + robotics" [1] Group 1: Technology and Business Model - The company has expanded its business from AI drug development to a broader "AI4S" platform, showcasing strong technological breadth and platform value [1] - The core technologies include breakthroughs in physical algorithms (crystal structure prediction + solid-state research), construction of underlying physical engines (XEF high-precision force field + XEP free energy perturbation), and expansion into drug modalities (small molecules + large molecules + peptides) [2] Group 2: Financial Performance - Revenue for 2022-2025H1 is projected to be 130 million, 170 million, 270 million, and 520 million yuan, with year-on-year growth rates of 112.3%, 30.8%, 52.8%, and 403.8% respectively [3] - The core business of drug discovery solutions secured a partnership with Dove Tree worth $5.99 billion, with an initial payment of $51 million received [3] Group 3: Market Potential and Technology Transfer - The company accelerates innovative drug development by enhancing efficiency in key stages such as target discovery, lead compound screening, and preclinical research, with multiple cases demonstrating the effectiveness of AI [4] - The underlying technology logic can be transferred to new materials and other fields, with the potential AI service market in drug research and materials development reaching nearly $50 billion in the long term [4] Group 4: Recent Developments and Future Projections - In 2025H1, the company made significant progress in its business, achieving important milestones in collaboration with Dove Tree and advancing multiple pipelines [5] - The company is expected to achieve revenues of 795 million, 985 million, and 1.421 billion yuan in 2025-2027, with year-on-year growth rates of 198%, 24%, and 44% respectively [5]

Investment Rating - The report initiates coverage with a "Buy" rating for the company [2][7]. Core Insights - The company is positioned as a leader in AI for drug discovery and has significant growth potential, with a projected market value of 487 billion RMB [6][7]. - Revenue is expected to grow substantially, with estimates of 795 million RMB, 985 million RMB, and 1.421 billion RMB for 2025, 2026, and 2027 respectively, reflecting year-on-year growth rates of 198%, 24%, and 44% [6][7]. - The company has established a comprehensive technology platform that integrates physical computing, AI, and automation in drug research and development [6][27]. Financial Data and Profit Forecast - Revenue projections for 2023 to 2027 are as follows: 174 million RMB, 266 million RMB, 795 million RMB, 985 million RMB, and 1.421 billion RMB, with corresponding growth rates of 30.80%, 52.75%, 198.39%, 23.92%, and 44.21% [5][6]. - The adjusted net profit is forecasted to be -522 million RMB, -457 million RMB, -23 million RMB, 75 million RMB, and 309 million RMB for the years 2023 to 2027, indicating a significant turnaround by 2025 [5][6]. - The company’s price-to-sales ratio (PS) is projected to be 47x, 38x, and 26x for 2025, 2026, and 2027 respectively, with a target PS of 49x for 2026 based on comparable companies [6][7]. Business Model and Market Position - The company focuses on drug discovery solutions as its core business, with significant revenue contributions from both drug discovery and automation solutions [6][31]. - The company has secured a major partnership with DoveTree, valued at 59.9 billion USD, which includes an upfront payment of 51 million USD [6][8]. - The technology is highly transferable, with applications extending beyond pharmaceuticals to new materials, indicating a potential market space of nearly 50 billion USD in the long term [9][58]. Technological Advancements - The company utilizes a combination of quantum physics, AI, and automation to enhance drug discovery processes, significantly reducing the time and cost associated with traditional methods [6][55]. - The integration of AI in drug development has been shown to cut research timelines by nearly half, as evidenced by various case studies [44][45]. - The company’s capabilities in both dry and wet lab environments provide a competitive edge in the AI-driven drug discovery landscape [6][27].

Core Insights - The company, based on quantum physics, integrates artificial intelligence and robotic automation technology to build a multi-modal AI model system for drug discovery, establishing a data-driven technology barrier [1] - The company has achieved significant revenue growth and is moving towards profitability, with a projected revenue of 2.66 billion yuan in 2024, a 53% year-on-year increase, and a net loss reduction to 15.2 billion yuan [2] - The company has established a strong technical barrier with over 6.5 million high-precision quantitative data points and 1.9PB of cloud data, along with more than 200 AI models [3] - The company is expanding its business model into new materials and other fields, with a significant order of 5.99 billion USD signed with DoveTree [4] - The company is rated "strongly recommended" due to its innovative drug discovery platform and expected revenue growth reaching 7.86 billion yuan by 2025 [5] Revenue and Profitability - In 2024, the company expects to generate 2.66 billion yuan in revenue, a 53% increase year-on-year, and a net loss of 15.2 billion yuan, showing a reduction in losses [2] - By the first half of 2025, the company has achieved profitability with a revenue of 5.17 billion yuan, a 404% year-on-year increase, and an adjusted net profit of 1.42 billion yuan [2] Technical Advantages - The company has accumulated over 6.5 million high-precision quantitative data points and 1.9PB of cloud data, with a monthly output of over 30,000 reaction data points [3] - The company possesses over 200 AI models, including globally leading algorithms such as the protein structure prediction algorithm XtalFold [3] - The company operates a state-of-the-art automated laboratory with over 200 robotic workstations and a 5000m² automated lab [3] Business Expansion and Collaborations - The company is pursuing a global development strategy, establishing a research and service network across the Americas, Europe, and Asia-Pacific [4] - The company has secured a pipeline cooperation order worth 5.99 billion USD with DoveTree, contributing positively to its performance [4] - The company is expanding its technology platform into new fields such as renewable energy, agriculture, and industrial materials [4] Future Outlook - The company is expected to achieve revenues of 7.86 billion yuan in 2025, with adjusted net profits projected to improve over the next few years [5] - The current stock price corresponds to a price-to-sales ratio of 53.44 for 2025, indicating potential for narrowing losses as scale effects materialize [5]

Investment Rating - The report assigns a "Buy" rating for the stock, indicating that it is expected to outperform the benchmark by more than 15% within the next six months [10]. Core Insights - The company has achieved significant revenue growth, with a 403.83% year-on-year increase in revenue to 517 million yuan in the first half of 2025, and a net profit of 83 million yuan, marking a turnaround from a loss of 1.237 billion yuan in the same period of 2024 [2]. - The drug discovery solutions segment saw a remarkable 615% increase in revenue, reaching 435 million yuan, driven by strategic collaborations and advancements in AI technology [2]. - The intelligent automation solutions segment also performed well, with a 95.9% increase in revenue to 82 million yuan, showcasing the effectiveness of AI and robotics in chemical processes [2]. Financial Performance Summary - Revenue projections for the company are as follows: 2024A: 266 million yuan, 2025E: 693 million yuan, 2026E: 984 million yuan, and 2027E: 1.337 billion yuan, reflecting a growth rate of 53%, 160%, 42%, and 36% respectively [4]. - The net profit forecast shows a recovery from a loss of 1.517 billion yuan in 2024A to a profit of 39 million yuan in 2025E, with further increases to 86 million yuan in 2026E and 184 million yuan in 2027E [4]. - The earnings per share (EPS) is projected to improve from -0.79 yuan in 2024A to 0.01 yuan in 2025E, 0.02 yuan in 2026E, and 0.05 yuan in 2027E [4]. Business Segment Performance - The drug discovery solutions segment is highlighted for its strong performance, with significant partnerships and awards enhancing its market position [2]. - The intelligent robotics solutions segment is noted for its innovative applications in chemical processes, achieving high success rates and operational efficiency [2]. - The company is leveraging AI and robotics to create a multi-dimensional innovation ecosystem, enhancing its capabilities in drug development and chemical research [2].

Core Insights - Jingtai Holdings (02228) demonstrated strong market appeal and execution capability through a textbook "lightning placement" by announcing a placement of up to approximately 286 million shares, raising HKD 2.65 billion [1] - The placement price was set at HKD 9.28 per share, representing a premium of approximately 75.8% over the IPO price and about 23.4% over the average closing price of the last 30 trading days, indicating high market recognition of the company's value [1] - The placement attracted significant interest from various institutional investors, including Norges Bank Investment Management, the world's largest sovereign wealth fund, reflecting strong confidence in the company's growth prospects [2] Financial Performance - In the first half of 2025, Jingtai Holdings achieved scale profitability for the first time, with revenue from drug discovery solutions increasing by 615.2% to HKD 435 million, and revenue from intelligent robotics solutions rising by 95.9% to HKD 82 million [2] - As of August 27, 2025, the company's market capitalization exceeded HKD 41.2 billion, making it the highest-valued company in the Asian AI drug discovery sector [2] - The company has a robust cash reserve of HKD 5.308 billion as of June 30, 2025, which, combined with the new financing, brings total cash reserves to approximately HKD 8 billion, providing a strong financial foundation for continued leadership in the field [3] Strategic Initiatives - Jingtai Holdings plans to utilize the proceeds from the placement for product and research iteration, commercialization expansion, and potential mergers and acquisitions, while also exploring innovative financial tools such as RWA (Real World Assets) and RDA (Real Data Assets) [1][4] - The company’s AI and robotics molecular discovery platform aligns well with the newly launched RWA registration platform in Hong Kong, which aims to facilitate the tokenization of real-world assets, enhancing asset liquidity and broadening financing channels for innovative drug development [4]

Core Insights - In the first half of 2025, XtalPi reported a revenue increase of 404% year-on-year, reaching 517 million RMB, and achieved a net profit of 141 million RMB, marking its first half-year profitability [1] - XtalPi is an innovative R&D platform leveraging quantum physics, AI, and robotics, providing drug and materials science development solutions [1] - The company is the first specialized technology firm to be listed on the Hong Kong Stock Exchange under Chapter 18C of the listing rules [1] - Among the top 20 global pharmaceutical companies, 16 are clients of XtalPi [1] Revenue Breakdown - The revenue from drug discovery solutions grew significantly, increasing from 60.85 million RMB in the first half of 2024 to 435.2 million RMB, a growth of 615.2% [2] - This growth in drug discovery solutions was driven by substantial upfront payments from major collaborations and the successful achievement of multiple pipeline milestones [2] - Revenue from intelligent robotics solutions also saw rapid growth, rising from 41.78 million RMB in the first half of 2024 to 81.86 million RMB, an increase of 95.9% [2] - The growth in intelligent robotics solutions was primarily fueled by the rapid expansion of automated chemical synthesis services and XtalPi's R&D solutions [2]

Core Viewpoint - JingTai Technology (2228.HK) has achieved significant recognition in the international capital market, evidenced by its impressive financial performance and strategic partnerships in the AI drug discovery sector [6][11]. Financial Performance - For the first half of 2025, JingTai Technology reported revenue of 517 million yuan, a year-on-year increase of 403.8%. The drug discovery solutions segment saw a revenue increase of 615.2% to 435 million yuan, while the intelligent robotics solutions segment grew by 95.9% to 82 million yuan [5]. - The company achieved its first half-year profit with an adjusted net profit of 142 million yuan [5]. - As of June 30, 2025, JingTai Technology held a cash balance of 5.308 billion yuan, indicating strong liquidity [6]. Market Position - JingTai Technology's market capitalization exceeded 41.2 billion HKD, making it the highest-valued company in the AI drug discovery field in Asia [6]. - The company ranked third in the Hong Kong Stock Connect trading activity, following Tencent and Alibaba [7]. Strategic Partnerships - A significant growth driver for JingTai Technology was its collaboration with biopharmaceutical legend Professor Gregory Verdine, which included a major agreement worth 51 million USD for the first phase and potential further payments totaling 589 million USD based on regulatory and commercial milestones [8][9]. - This partnership is expected to leverage JingTai's AI and robotics drug discovery platform to develop small molecules and antibody candidates for various diseases [9][10]. Technological Advancements - JingTai Technology's AI antibody drug structure modeling platform, XtalFold, was recognized as one of the top ten innovative AI technologies at the World Artificial Intelligence Conference [13]. - The company has developed a unique high-throughput experimental system that integrates advanced visual perception, AI, and robotics, addressing significant challenges in chemical research [15][16]. R&D Investment - In the first half of the year, JingTai Technology increased its R&D investment by 5.3% to 222 million yuan, reflecting a commitment to innovation despite a much higher revenue growth rate [16]. Long-term Value Proposition - JingTai Technology is positioned as a platform company with core competencies in AI and data, capable of empowering various sectors including biomedicine, new materials, and renewable energy, thus representing significant long-term value [18].