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医药生物行业跟踪周报:PD1/VEGF双抗引领新一代IO,建议关注康方生物、神州细胞等-20250706
Soochow Securities· 2025-07-06 07:45
Investment Rating - The report maintains a rating of "Overweight" for the pharmaceutical and biotechnology industry [1] Core Insights - The PD1/VEGF dual antibody is leading the next generation of immuno-oncology (IO) treatments, with significant attention on companies like Kangfang Biopharma and Shenzhou Cell [5][6] - The report highlights the approval of the first domestic recombinant human coagulation factor VIIa by Zhengda Tianqing, marking a significant milestone in the industry [2] - The report suggests a ranking of favored sub-industries: innovative drugs > research services > CXO > traditional Chinese medicine > medical devices > pharmacies [3][12] Summary by Sections Industry Performance - The A-share pharmaceutical index has increased by 3.9% this week and 10% year-to-date, outperforming the CSI 300 by 3.0% and 8.9% respectively [6][11] - The H-share biotechnology index has seen a rise of 5.0% this week and 62% year-to-date, outperforming the Hang Seng Technology Index by 7.3% and 44% respectively [6][11] R&D Progress and Company Dynamics - The report details the significant advancements in innovative drugs, including the initiation of Phase III clinical trials for HER2 dual antibodies by Zhengda Tianqing [2] - It emphasizes the competitive edge of PD1/VEGF dual antibodies, particularly the success of Kangfang Biopharma's Ivosidenib in clinical trials against the leading PD-1 inhibitor, Pembrolizumab [17][23] Market Insights - The report notes that the pharmaceutical sector has shown strong performance, particularly in innovative drugs, with significant gains in stock prices for companies like Saily Medical (+55%) and Shenzhou Cell (+47%) [6][11] - The report also highlights the performance of various sub-sectors, with chemical drugs and biological products showing substantial price increases [6][11] Specific Company Recommendations - The report recommends focusing on companies such as Shenzhou Cell, Huahai Pharmaceutical, and Rongchang Biopharma from the perspective of PD1/VEGF dual antibodies [3][12] - It also suggests looking at companies with strong growth potential like Borui Pharmaceutical and Innovent Biologics, as well as those with low valuations such as Zhaoli Pharmaceutical and Dong'e Ejiao [3][12]