证券研究报告 医药生物 行业定期报告 hyzqdatemark 2025 年 05 月 19 日 板块表现： 长春高新，涅槃重生？ 投资评级： 看好（维持） ——医药行业周报（25/5/12-25/5/16） 投资要点： 请务必仔细阅读正文之后的评级说明和重要声明 证券分析师 本周医药市场表现分析：5 月 12 日至 5 月 16 日，医药指数上涨 1.27%，相对沪深 300 指数 超额收益为+0.16%。本周题材性个股表现较好，拓新药业、川宁生物、华大基因等。建议关 注：1）创新药作为产业趋势，近期盘整较为充分，继续重点推荐 A 股信立泰、科伦药业、热 景生物、一品红、科兴制药、恒瑞医药；港股三生制药、科伦博泰、康方生物、中国生物制 药；2）业绩落地、估值较低的个股，建议关注长春高新（创新药）、昆药集团、开立医疗、 迈瑞医疗、鱼跃医疗、海泰新光等；3）Ai/科技+医疗，建议关注华大智造、麦澜德、三友医 疗、润达医疗、塞力医疗、乐心医疗等。 联系人 医药指数和各细分领域表现、涨跌幅：本周医药指数上涨 1.27%，上涨个股数量 345 家，下 跌个股 138 家，涨幅居前为拓新药业（+45.03%）、永安药业 ...

Investment Rating - The report suggests a positive outlook on the pharmaceutical industry, particularly focusing on innovative drugs and potential treatments for cancer cachexia [1][11]. Core Insights - The report highlights the complexity of cancer cachexia and the limited treatment options currently available, emphasizing the importance of developing targeted therapies [17][18]. - It identifies key companies to watch, including Changchun High-tech, Kexing Pharmaceutical, Sunshine Nuohuo, Shiyao Group, and Jinfang Pharmaceutical, which are involved in promising drug candidates [1][17]. - The report anticipates a structural bull market in the pharmaceutical sector, driven by innovative drugs and new technologies [3][14]. Summary by Sections 1. Industry Performance - The pharmaceutical index increased by 1.27% during the week of May 12-16, underperforming the ChiNext index but outperforming the CSI 300 index [1][12]. 2. Cancer Cachexia Insights - Cancer cachexia affects 60%-80% of cancer patients, with approximately 20% of these patients dying from it, highlighting the critical need for effective treatments [17]. - The report discusses the mechanisms of cancer cachexia, including metabolic abnormalities and inflammatory responses, which complicate treatment options [18][21]. 3. Potential Drug Targets - The report identifies GDF15/GFRAL and GHSR as key potential drug targets for cancer cachexia, with several companies developing therapies targeting these pathways [27][35]. - Notable drug candidates include ponsegromab by Pfizer, which has shown promising results in clinical trials [33]. 4. Investment Strategies - The report outlines investment strategies focusing on innovative drugs, including overseas big pharma, early-stage research, and undervalued generics [15][16]. - It emphasizes the importance of self-sufficiency and restructuring the supply chain within the pharmaceutical industry [5][14]. 5. Future Outlook - The report predicts a favorable trading atmosphere for the pharmaceutical sector in 2025, with a high likelihood of structural growth driven by innovative drugs and new technologies [3][14].

Strategic Planning - The company emphasizes the importance of long-term strategic vision in innovative drug development, particularly in international expansion beyond the U.S. market [2] - The potential overseas transaction value for the company reached $14 billion by the end of 2024, highlighting the urgency of international business development [3] - The company is actively pursuing a strategic transformation to build a high-expectation, high-tech, and high-barrier second growth curve [3] Product Development - The company has a mature growth hormone industry with 12 approved indications, maintaining a leading market share in China [4] - The long-acting growth hormone product has undergone extensive clinical trials, demonstrating safety and efficacy over three years with over 10,000 real-world applications [4] - The company is expanding its product pipeline, with several new products expected to be approved in 2025, including liquid flu vaccines and long-acting follicle-stimulating hormones [6][7] Financial Performance - The company is experiencing increased expenses due to new product development and market promotion, which may impact short-term performance [13] - The company plans to control costs while ensuring the smooth implementation of strategic plans [14] - The company has a profit distribution plan for 2024, with a commitment to maintain a minimum dividend payout ratio of 40% [15] Research and Development - The company is focused on enhancing its R&D capabilities, with ongoing projects in various therapeutic areas, including pediatric and women's health [9] - The Shanghai R&D headquarters is under construction, aiming to consolidate global biopharmaceutical innovation resources [11] - The company is committed to increasing R&D investment sustainably while ensuring a favorable return on investment [10] Market Expansion - The company is prioritizing international market development, leveraging domestic strengths to enhance overseas sales [12] - The company is actively pursuing regulatory approvals for its products in foreign markets, adapting to varying requirements [12] - The company is exploring potential licensing opportunities for its innovative drugs [12] Operational Efficiency - The company is optimizing its sales team efficiency and focusing on core product lines to enhance commercialization capabilities [14] - The company is implementing cost-saving measures while maintaining a stable core team [18] - The company is transitioning its real estate operations towards a lighter asset model, integrating with its pharmaceutical projects [18] Governance and Compliance - The company adheres to strict regulations regarding related party transactions, ensuring transparency and compliance [20] - The company is committed to improving investor relations and information disclosure practices [20]