Core Insights - The article discusses the emergence of three companies, He Yuan Bio, Xi'an Yicai, and Bibet, as leaders in the newly established Sci-Tech Growth Tier, despite all being unprofitable firms. These companies have demonstrated strong capabilities in "hard technology" [1][3] Group 1: Company Highlights - Xi'an Yicai is a rising star in the semiconductor industry, ranking as the top domestic and sixth globally in 12-inch silicon wafer production, with a projected monthly shipment volume and capacity accounting for approximately 6% and 7% of the global market, respectively [1] - He Yuan Bio has developed a globally pioneering "rice-derived blood" technology, with its recombinant human albumin injection approved for market in July, addressing the long-standing reliance on imported human serum albumin in China [2] - Bibet focuses on innovative drug development for major diseases, with its first-class innovative drug BEBT-908 approved for market in June, targeting relapsed or refractory diffuse large B-cell lymphoma patients [2] Group 2: Industry Trends - The introduction of the "1+6" policy by the China Securities Regulatory Commission has led to the establishment of the Sci-Tech Growth Tier, which includes 32 unprofitable listed companies primarily in strategic emerging industries such as new-generation information technology and biomedicine [3] - These 32 companies have collectively invested 30.6 billion yuan in R&D, with a median R&D expenditure to revenue ratio of 65.4%, indicating a strong commitment to innovation [3] - The growth of innovative drug companies in the Sci-Tech Growth Tier has resulted in the launch of 20 new national class 1 drugs, showcasing significant potential for development and commercialization [3] Group 3: Market Opportunities - Several innovative drug companies have successfully executed overseas licensing agreements, with potential transaction values totaling nearly 5 billion USD, indicating a robust international market presence [4] - In the semiconductor sector, companies like ChipLink Integrated have become major players in the automotive-grade IGBT market, while firms like Cambricon are enhancing AI computing capabilities [5] - The growth of the Sci-Tech Growth Tier reflects the quality of growth among hard technology enterprises and the capacity of the reform "testbed" [5]

Core Insights - The establishment of the "Science and Technology Innovation Growth Layer" aims to bridge the gap between "technological breakthroughs" and "capital infusion" for high R&D, currently unprofitable hard technology entities [3][11] - Companies like Cambricon have successfully transitioned to this new layer, securing significant funding to enhance their competitiveness in the smart chip industry [1][3] - The growth layer has attracted a variety of new companies, indicating a robust pipeline for future IPOs and capital market engagement [4][11] Group 1: Company Developments - Cambricon, a domestic AI chip company, has raised 3.985 billion yuan for hardware and software development, marking a significant turnaround after years of losses [1] - The rapid IPO process of companies like Moore Threads, which took only 88 days from acceptance to approval, highlights the efficiency of the new growth layer [1] - The growth layer has seen 32 companies transition into it, with 18 new applications submitted, indicating a strong influx of new entrants [4] Group 2: Industry Impact - The growth layer is designed to support the development of the new generation of information technology, enhancing confidence in the hard technology sector [3][6] - Companies in the growth layer are addressing critical core technology issues, contributing to the self-sufficiency of China's information industry [6] - The layer has facilitated significant advancements in various sectors, including semiconductors, AI computing, and telecommunications, showcasing the potential for domestic alternatives [7][8] Group 3: Future Outlook - Many companies are focusing on long-term R&D investments to capture new growth opportunities, particularly in emerging fields like intelligent robotics [10] - The introduction of more inclusive policies and standards aims to create a favorable capital ecosystem for hard technology enterprises [11] - The growth layer's supportive environment has enabled companies like Obsidian to achieve profitability after previously being unprofitable, demonstrating the effectiveness of the new capital market dynamics [10]

Core Insights - The article discusses the upcoming listing of He Yuan Bio, Xi'an Yicai, and Bibet on the Sci-Tech Innovation Board, marking them as the first batch of newly registered companies in the Sci-Tech Growth Layer [3] - The Sci-Tech Growth Layer aims to support technology enterprises and enhance their development through a more inclusive and adaptable listing system [3][4] Group 1: Market Overview - The total market capitalization of the 32 existing companies in the Sci-Tech Growth Layer exceeds 1 trillion yuan, with significant representation in new-generation information technology (15 companies), biomedicine (14 companies), new energy (2 companies), and high-end equipment manufacturing (1 company) [4] - These companies have collectively raised 105.2 billion yuan through IPOs, facilitating increased R&D investment and commercialization efforts [4] Group 2: Financial Performance - In 2024, the 32 companies are projected to achieve a total revenue of 67.6 billion yuan, with 29 companies surpassing 100 million yuan in revenue [6] - The average annual compound growth rate of revenue for these companies is 27.87%, outpacing the overall growth rate of the Sci-Tech Board by nearly 4 percentage points [6] - Despite ongoing losses due to high R&D costs and product introduction phases, 19 companies are expected to reduce their losses year-on-year in 2024, with 16 companies reducing losses by over 20% [6] Group 3: R&D and Innovation - The 32 companies are expected to invest a total of 30.6 billion yuan in R&D in 2024, with a median R&D expenditure to revenue ratio of 65.4%, leading the Sci-Tech Board [7] - Notable achievements include the launch of 20 new drugs with global novelty and the development of significant AI technologies, enhancing the competitive edge of domestic firms [7] Group 4: Institutional Support - Recent reforms, including the "1+6" initiative, have provided tailored support for companies at different stages, facilitating easier access to financing for R&D projects [8] - The merger and acquisition framework has also been improved, allowing companies to pursue external growth strategies more effectively [8]

Core Insights - The article discusses the upcoming listing of He Yuan Bio, Xi'an Yicai, and Bibet on the Sci-Tech Innovation Board, marking them as the first batch of newly registered companies in the Sci-Tech Growth Layer [1][2]. Group 1: Overview of the Sci-Tech Growth Layer - The Sci-Tech Growth Layer was established as part of the "1+6" reform, allowing 32 existing unprofitable companies to enter this layer, which aims to better serve the needs of technology enterprises and new productive forces [2][3]. - The total market capitalization of the 32 existing companies exceeds 1 trillion yuan, with significant representation in strategic emerging industries such as new generation information technology (15 companies) and biomedicine (14 companies) [3]. Group 2: Financial Performance and Growth - The 32 existing companies have collectively raised 105.2 billion yuan through IPOs, which has catalyzed their R&D investments and commercial capabilities [3]. - In 2024, these companies are projected to achieve a total revenue of 67.6 billion yuan, with 29 companies surpassing 100 million yuan in revenue [4]. - The average annual compound growth rate of revenue for these companies is 27.87%, outperforming the overall growth rate of the Sci-Tech Innovation Board by nearly 4 percentage points [4]. Group 3: R&D and Innovation - The 32 companies are expected to invest a total of 30.6 billion yuan in R&D in 2024, with a median R&D expenditure to revenue ratio of 65.4%, leading the Sci-Tech Innovation Board [5]. - Notable achievements include the launch of 20 globally innovative Class 1 new drugs by the innovative pharmaceutical sector, with significant contributions from companies like BeiGene and Zai Lab [5]. Group 4: Institutional Support and Future Prospects - Recent reforms, including the "Sci-Tech Board Eight Articles" and "M&A Six Articles," provide tailored support for companies at different stages, facilitating their growth and development [6]. - The entry of new companies like He Yuan Bio, Xi'an Yicai, and Bibet into the Sci-Tech Growth Layer is expected to further expand the sector, alongside other unprofitable companies applying for IPOs [6].

Core Insights - The launch of the "1+6" reform on June 18 has established the Sci-Tech Innovation Board's growth tier, allowing 32 unprofitable listed companies to enter this tier, leading to increased revenue and reduced losses, with a total market value exceeding 1 trillion yuan [1][2]. Group 1: Growth Tier Companies - Recent IPOs include He Yuan Bio, Xi'an Yicai, and Bibete, which will directly enter the growth tier, contributing to a total of 54 unprofitable companies listed since the board's inception, with 22 achieving profitability post-listing [2]. - The growth tier companies are primarily in strategic emerging industries, including new-generation information technology (15 companies), biomedicine (14 companies), new energy (2 companies), and high-end equipment manufacturing (1 company) [3]. - The growth tier companies have collectively raised 105.2 billion yuan through IPOs, facilitating increased R&D investment and capacity building [3]. Group 2: Financial Performance - In 2024, the 32 growth tier companies achieved a total revenue of 67.6 billion yuan, with 29 companies surpassing 100 million yuan in revenue [5]. - The average annual compound growth rate of revenue for these companies is 27.87%, outperforming the overall board's growth rate by nearly 4 percentage points [5]. - By the first half of 2025, the growth tier companies experienced a year-on-year revenue increase of 37.79%, indicating a strong growth trend [5]. Group 3: Loss Reduction - In 2024, 19 growth tier companies reduced their losses year-on-year, with 16 companies reducing losses by over 20% [6]. - By the first half of 2025, the overall loss reduction amounted to 7.12 billion yuan, with 21 companies reducing losses, and 13 of them by over 20% [6]. - Notable examples include Baijie Shenzhou, which transitioned from a loss of 13.6 billion yuan in 2022 to a profit of 450 million yuan in 2025, and Hanwujing, which achieved profitability for four consecutive quarters starting from Q4 2024 [6]. Group 4: R&D Investment - The 32 growth tier companies invested a total of 30.6 billion yuan in R&D in 2024, with a median R&D investment to revenue ratio of 65.4%, leading the Sci-Tech Innovation Board [8]. - The board's support has enabled these companies to achieve significant R&D milestones, including the launch of 20 new drugs with global innovation attributes [8]. - For instance, Baijie Shenzhou's fundraising efforts have led to the successful development of Zebutini, which became the first domestic drug to exceed 1 billion USD in sales [8]. Group 5: Institutional Support - The "1+6" reform and related policies have provided tailored support for growth tier companies, facilitating their financing and development [10]. - Eight growth tier companies have completed refinancing, raising a total of 13.2 billion yuan, with over 30% of the funds allocated to R&D [10]. - The merger and acquisition framework has also been enhanced, with six disclosed transactions since the introduction of the "Sci-Tech Board Eight Articles," focusing on acquiring quality unprofitable companies [11].

Core Insights - The article discusses the upcoming listing of He Yuan Bio, Xi'an Yicai, and Bibet on the Sci-Tech Innovation Board, marking them as the first batch of newly registered companies in the Sci-Tech Growth Layer [1] - The Sci-Tech Growth Layer aims to support technology enterprises and enhance new productive forces through a more inclusive and adaptable listing system [1][2] Group 1: Market Overview - The total market capitalization of the 32 existing companies in the Sci-Tech Growth Layer exceeds 1 trillion yuan, with significant representation in new generation information technology (15 companies), biomedicine (14 companies), new energy (2 companies), and high-end equipment manufacturing (1 company) [2] - These companies have collectively raised 105.2 billion yuan through IPOs, facilitating increased R&D investment and capacity building [2] Group 2: Financial Performance - The 32 companies in the Sci-Tech Growth Layer are projected to achieve a total revenue of 67.6 billion yuan in 2024, with 29 companies surpassing 100 million yuan in revenue [3] - The average annual compound growth rate of revenue for these companies is 27.87%, outpacing the overall growth rate of the Sci-Tech Board by nearly 4 percentage points [3] - In 2025, the companies are expected to see a year-on-year revenue growth of 37.79%, indicating a strong growth trend [3] Group 3: R&D Investment - The total R&D investment of the 32 companies is expected to reach 30.6 billion yuan in 2024, with a median R&D investment to revenue ratio of 65.40%, leading the Sci-Tech Board [4] - The innovative drug sector has seen significant advancements, with 20 new drugs achieving "global new" status and 10 drugs receiving breakthrough therapy designations [4] Group 4: Technological Advancements - New generation information technology companies are accelerating their technological advancements, with notable products like DeepSeek and the DeepEdge 10 chip entering the market [5] - These advancements are enhancing China's competitiveness in international standards and technology [5] Group 5: Institutional Support - Recent reforms and institutional innovations, such as the "1+6" reform, are providing tailored support for companies at different stages of development [6] - The new refinancing standards and merger regulations are facilitating external growth and R&D funding for companies in the Sci-Tech Growth Layer [6]

Core Viewpoint - The article discusses the upcoming listing of new companies on the Sci-Tech Innovation Board, highlighting the establishment of the Sci-Tech Growth Layer and its implications for technology enterprises and innovative production capabilities [1][9]. Group 1: Overview of the Sci-Tech Growth Layer - The Sci-Tech Growth Layer will include three new companies: He Yuan Bio, Xi'an Yicai, and Bibet, joining 32 existing companies that have not yet turned a profit [1]. - The total market capitalization of the existing 32 companies exceeds 1 trillion yuan [2]. - These companies are primarily distributed across strategic emerging industries, including new-generation information technology (15 companies), biomedicine (14 companies), new energy (2 companies), and high-end equipment manufacturing (1 company) [3]. Group 2: Financial Performance and Growth - The 32 existing companies have collectively raised 105.2 billion yuan through IPOs, which has catalyzed their research and development investments, capacity building, and commercialization efforts [3]. - In 2024, these companies are projected to achieve a total revenue of 67.6 billion yuan, with 29 companies surpassing 100 million yuan in revenue [5]. - The average annual compound growth rate of revenue for these companies since 2019 is 27.87%, outpacing the overall growth rate of the Sci-Tech Innovation Board by nearly 4 percentage points [5]. Group 3: Trends in Profitability - Among the 54 unprofitable companies listed on the Sci-Tech Board, 22 have achieved profitability and "delisted" from the unprofitable category, averaging 4 companies per year [5]. - In 2024, 19 companies are expected to reduce their losses year-on-year, with 16 of them reducing losses by over 20% [6]. - In the first half of 2025, the existing companies in the Sci-Tech Growth Layer significantly reduced losses by 7.1 billion yuan, with 21 companies reducing losses, and 13 of them achieving a reduction of over 20% [6]. Group 4: Research and Development Investment - The total R&D investment of the 32 companies is expected to reach 30.6 billion yuan in 2024, with a median R&D investment-to-revenue ratio of 65.4%, leading the Sci-Tech Innovation Board [8]. - The innovative drug sector has entered a "harvest period," with these companies launching 20 new drugs classified as "global new" and achieving breakthrough therapy designations for 10 drugs [8]. Group 5: Institutional Support and Future Prospects - Recent reforms, including the "1+6" reform, have provided tailored support for companies at different stages, facilitating their growth and development [10]. - The new financing standards allow companies to exceed refinancing limits for R&D projects, with some companies allocating over 30% of raised funds to R&D [10]. - The growth trajectory of the Sci-Tech Growth Layer companies is becoming clearer, with new companies expected to join the layer, further enriching the sector [10].

1、n 本次股票发行后拟在科创板市场上市，该市场具有较高的投资风险。科 创板公司具有研发投入大、经营风险高、业绩不稳定、退市风险高等特点， 投资者面临较大的市场风险。投资者应充分了解科创板市场的投资风险及本 公司所披露的风险因素，审慎作出投资决定。 深圳云天励飞技术股份有限公司 （深圳市龙岗区园山街道龙岗大道 8288 号深圳大运软件小镇 17 栋 1 楼） 首次公开发行股票并在科创板 上市招股说明书 （注册稿） 本公司的发行申请尚需经上海证券交易所和中国证监会履行相应程序。 本招股说明书不具有据以发行股票的法律效力，仅供预先披露之用。投资者 保荐机构（主承销商） （广东省深圳市福田区中心三路 8 号卓越时代广场（二期）北座） 保荐机构（主承销商） 应当以正式公告的招股说明书作为投资决定的依据。 深圳云天励飞技术股份有限公司 首次公开发行股票并在科创板上市招股说明书（注册稿） 监管机构声明 中国证监会、交易所对本次发行所作的任何决定或意见，均不表明其对注册 申请文件及所披露信息的真实性、准确性、完整性作出保证，也不表明其对发行 人的盈利能力、投资价值或者对投资者的收益作出实质性判断或保证。任何与之 相反的声明 ...