进入2026年，珍宝岛（603567）药业在全国多地的生产基地一派蓬勃气象，处处涌动着赶产奋进的昂扬 热潮。各条智能制造生产线高速稳定运行，一箱箱成品有序下线，发往全国各地。据副总裁白铁忠介 绍："目前，公司核心制剂生产线均处于满负荷生产状态，2026年第一季度的生产计划已经排满。尤其 是心脑、呼吸系统产品如注射用血塞通、舒血宁注射液、血栓通胶囊、复方芩兰口服液等市场需求稳 定。" 中间体运往虎林、哈尔滨等地的生产基地后，在珍宝岛冻干制剂智能生产车间，AGV移动式自动进出 料系统在精密而静谧地运行着。整个过程中，MES系统全程记录每个批次的工艺数据、质量检验结果 与设备状态，形成完整的数字化档案，实现从原料到成品的全程可追溯。此外，各类检测设备动采集并 整合流动相、红外光谱、有机碳测定、等离子质谱等关键质量数据，让产品质量控制更加客观、精准。 "智能化不只是提高生产力，更是对生产过程的重新定义。"白铁忠表示，"我们通过SCADA系统(数据 采集与监控系统)实时监控上百个工艺控制点，任何偏离标准值的波动都会触发预警，确保每一批产品 都严格遵循预定工艺路径生产。这让我们即使在满负荷运行下，也能保持产品批次间的高度 ...

Group 1 - The core business of the company is traditional Chinese medicine, which has laid a solid foundation for its growth, with key products covering various medical terminals in China [2][3] - The company is expanding into the biopharmaceutical sector, with its investment in Zhejiang Teruisi Pharmaceutical Co., Ltd. entering a value realization phase, particularly with the ADC drug TRS005 receiving breakthrough therapy designation [1][5][7] - The company has launched a new innovative Chinese medicine product, Qingjiang Hewei Granules, which targets a complex condition with limited treatment options, potentially opening a market worth over 1 billion yuan [3][4] Group 2 - The biopharmaceutical market is experiencing significant growth, with ADCs being recognized as a promising platform product, projected to exceed $16.4 billion globally by 2026 [5] - The company has made strategic investments in the biopharmaceutical field, with Teruisi's TRS005 focusing on unmet clinical needs in non-Hodgkin lymphoma, marking a significant step in the company's transformation [6][7] - The company is also advancing in the chemical drug sector, with its independently developed raw material for an antihistamine drug receiving regulatory approval, indicating a strong market presence in a high-barrier segment [8][9] Group 3 - The company's dual-track strategy in chemical drugs, focusing on both raw materials and formulations, has been successfully implemented, enhancing its competitive position in the market [9][10] - The combination of traditional Chinese medicine, biopharmaceuticals, and chemical drugs creates a diversified growth strategy for the company, ensuring a more certain trajectory for future performance [10]

Core Viewpoint - Zhenbaodao, a well-known high-end traditional Chinese medicine company, faces challenges in revenue and profitability, ranking low in the industry despite its strong R&D capabilities and full industry chain advantages [1][2]. Group 1: Company Overview - Established on October 28, 1996, Zhenbaodao was listed on the Shanghai Stock Exchange on April 24, 2015, and is headquartered in Heilongjiang Province [1]. - The company specializes in high-end traditional Chinese medicine formulations, with a diverse range of products and dosage forms [1]. Group 2: Financial Performance - For Q3 2025, Zhenbaodao reported revenue of 918 million yuan, ranking 44th out of 69 in the industry, significantly lower than the top competitors, Baiyunshan (61.606 billion yuan) and Yunnan Baiyao (30.654 billion yuan) [2]. - The net profit for the same period was -376 million yuan, placing the company last in the industry, while the industry leaders reported net profits of 4.789 billion yuan and 3.398 billion yuan, respectively [2]. Group 3: Financial Ratios - As of Q3 2025, Zhenbaodao's debt-to-asset ratio was 38.22%, an increase from 35.06% year-on-year, exceeding the industry average of 32.81% [3]. - The gross profit margin was 35.71%, down from 53.10% year-on-year and below the industry average of 52.44%, indicating a decline in profitability [3]. Group 4: Executive Compensation - The chairman, Fang Tonghua, received a salary of 2.6798 million yuan in 2024, a slight decrease from 2.6936 million yuan in 2023 [4]. - The general manager, Yan Jiujiang, earned 1.1708 million yuan in 2024, a marginal increase from 1.1705 million yuan in 2023 [4]. Group 5: Shareholder Information and Market Outlook - As of September 30, 2025, the number of A-share shareholders decreased by 2.72% to 20,900, while the average number of shares held per shareholder increased by 2.80% to 45,000 [5]. - Huaxin Securities predicts that Zhenbaodao's revenue will grow to 1.984 billion yuan in 2025, 2.823 billion yuan in 2026, and 3.066 billion yuan in 2027, with corresponding EPS of 0.07, 0.50, and 0.54 yuan [5].

Investment Rating - The report assigns a "Buy" rating for the company, marking it as the first recommendation [1]. Core Insights - The company is expected to face short-term impacts from centralized procurement, but sales are anticipated to improve post-implementation. The net profit for the first half of 2025 is projected to be between -77 million and -66 million yuan, primarily due to delayed procurement timelines and price reductions on core products, leading to a 57% decline in revenue and a 64% drop in gross profit year-on-year [3][4]. - The company has made significant progress in the development of innovative traditional Chinese medicine, with a key milestone achieved in the clinical trial of Qingjiang Hewei Granules, which targets a complex syndrome of non-erosive gastroesophageal reflux disease [5]. - The company holds a 17.0211% stake in Zhejiang Tereis, which is developing a first-in-class ADC product, TRS005, showing promising clinical results for treating relapsed or refractory CD20-positive diffuse large B-cell lymphoma [6][7]. Summary by Sections Financial Performance - The company is expected to see a revenue decline in 2025, with projections of 1.984 billion yuan, followed by a recovery to 2.823 billion yuan in 2026 and 3.066 billion yuan in 2027. The earnings per share (EPS) are forecasted to be 0.07 yuan in 2025, 0.50 yuan in 2026, and 0.54 yuan in 2027, with corresponding price-to-earnings (P/E) ratios of 185.9, 24.8, and 23 respectively [8][10]. Market Position and Growth Drivers - The company’s core products are expected to regain sales momentum following the implementation of centralized procurement, which is anticipated to positively impact revenue in the latter half of 2025 [4]. - The innovative drug development and the ADC platform are seen as potential growth drivers for the company, with the ADC product expected to receive regulatory approval in 2024 [6][8]. Investment Outlook - The report suggests that despite short-term challenges due to procurement policies, the company’s innovative drug pipeline and strategic partnerships could lead to significant growth in the coming years, justifying the "Buy" rating [8].

Investment Rating - The report maintains a strong rating for the pharmaceutical and biotechnology sector, indicating it is expected to outperform the market [6]. Core Insights - The report highlights the breakthrough therapy of TRS005, an ADC targeting CD20, which shows potential to outperform existing treatments for DLBCL [4][40]. - The DLBCL market is projected to grow significantly, with the Chinese market expected to increase from RMB 58 billion in 2019 to RMB 186 billion by 2024, and further to RMB 369 billion by 2030, reflecting a CAGR of 26.2% [21][24]. - The report emphasizes the importance of innovative drugs and suggests focusing on companies with strong performance and potential catalysts in the upcoming quarters [4][5]. Summary by Sections 1. Market Review - The CITIC Pharmaceutical Index rose by 1.5% during the week of June 23-27, 2025, underperforming the CSI 300 Index by 0.5 percentage points [3][49]. - The top five performing stocks included Shenzhou Cell (+30.5%), Haooubo (+27.1%), and Huaren Health (+26.0%) [3][63]. 2. DLBCL and ADC Treatment - DLBCL accounts for approximately 30-40% of all NHL cases, with a significant portion of patients remaining untreated despite existing therapies [4][17]. - The report discusses the transition from traditional chemotherapy to targeted therapies, highlighting the introduction of ADCs as a promising treatment avenue [24][27]. - TRS005 has shown promising results in early trials, with an overall response rate (ORR) of 59.4% in the 1.8 mg/kg dosage group [42][46]. 3. Investment Recommendations - The report suggests a focus on innovative drugs as a long-term investment strategy, particularly in companies that are expected to report strong Q2 earnings [4][5]. - Recommended stocks include Innovent Biologics, Kintor Pharmaceutical, and Zhenbao Island, among others [5][13]. 4. Industry Trends - The report notes that the ADC sector is gaining traction, with TRS005 being a key focus due to its potential advantages over existing therapies [40][47]. - The overall pharmaceutical sector is experiencing a shift towards innovative treatments, driven by advancements in technology and an aging population [21][24].