创新抗乙肝和丁肝药物立贝韦塔（HH-003）单抗是新一代靶向HBV Large（L）蛋白的PreS1区域，具有 免疫清除病毒功能的入侵抑制剂。该药物已分别被中国国家药监局和美国药监局（FDA）授予"突破性 疗法"资格，2024年12月新药上市申请（NDA）正式获得中国国家药监局受理并获得优先审评审批资 格，2025年年底或2026年年初有望获得附条件批准上市。 ...

Core Insights - The innovation process in the pharmaceutical industry is extremely challenging, with an average time of 10 years and a cost of 1 billion USD from target discovery to market launch, while the success rate is less than 10% [1] Company Insights - 诺诚健华 has been recognized for its innovative journey over the past decade, highlighting the importance of continuous research and development in the pharmaceutical sector [1] - The company benefits from the supportive research policies and industrial ecosystem in Beijing, which provide a conducive environment for growth [1] Industry Insights - China's innovative drugs have become a part of global innovation, representing a new form of productive force in the industry [1]

为了让更多人感受到藏式茶饮的独特风味，喜茶推出瓶装饮料市场首款咸酪藏茶牛乳茶产品。喜茶基于 门店藏地茶饮的研发经验，对这款产品的原料品质、生产工艺等都进行了严格把控和创新研发。在工艺 方面，喜茶基于此前门店现制产品的研发经验，对藏茶茶底的萃茶工艺进行了创新。此次上新瓶装咸酪 藏茶，喜茶通过门店现制产品和瓶装产品的组合方式，为消费者带来了藏地风物体验，持续推动藏茶品 类出圈。 喜茶自2020年推出瓶装产品以来，始终以门店现制饮品为灵感，通过门店现制产品洞察消费者需求，进 行差异化的瓶装产品研发。今年6月，喜茶在山姆推出了瓶装超级植物茶产品——羽衣甘蓝青瓜，这款 瓶装产品灵感源自喜茶门店的超级植物茶系列；而去年喜茶在山姆推出的特浓抹茶也同样成为爆款。 新京报讯(记者王子扬)11月3日，新京报记者了解到，新茶饮企业喜茶推出全新瓶装产品——咸酪藏茶 牛乳茶，迅速成为会员制商店山姆酒水饮料新品榜中茶饮销量第一名。同时，喜茶门店回归了"雪域.牦 牛乳恰安莫""牦牛乳酥油茶"系列产品，进行门店现制与瓶装产品的组合联动。据了解，这款产品是喜 茶在山姆推出的第8款定制瓶装产品。 ...

据新华社北京11月3日电 记者11月3日从司法部获悉，为督促行政执法人员树牢执法为民理念，提升企 业和群众的获得感、幸福感、安全感，推动规范涉企行政执法专项行动进一步走深走实，司法部发布 《行政执法人员行为准则》。 行为准则共10条，聚焦目前企业和群众反映强烈的行政执法突出问题，尤其是规范涉企行政执法专项行 动明确的四类重点问题，从正面引导和负面禁令两个方面逐条作了规定：一是严格遵循职权法定，二是 严格做到积极履行法定职责，三是严格按照法律规定和客观事实执法，四是严格做到公正执法，五是严 格遵守法定程序，六是严格推进文明执法，七是严格做到执法与服务相结合，八是严格遵守纪律规定， 九是严格遵守行政执法案卷归档保存规定，十是严格遵守保密规定。 司法部有关负责人介绍，行为准则将以往散见于法律法规、有关制度文件的规定进行归纳、整理和提 炼，凝聚成通俗易懂的内容。一方面突出正面引导，督促行政执法人员树立正确的执法理念，提升规范 执法意识。另一方面强调负面禁令，对一些既往规定中的禁止性内容进行了系统重申，明确行政执法人 员行为红线，便于行政执法人员全面掌握和严格遵守。 在规范行政执法主体、人员、行为和程序等方面，行为准则 ...

停牌期间，公司将根据上述事项进展情况，严格按照有关法律、法规的规定及时履行信息披露义务。待 上述事项确定后，公司将及时发布相关公告并申请公司股票复牌。 新京报贝壳财经讯11月3日，维信诺（002387）发布公告称，公司正在筹划向特定对象发行A股股票事 宜，该事项可能导致公司控制权发生变更，具体方案尚需进一步论证和磋商。鉴于上述事项尚存在重大 不确定性，根据有关规定，经公司向深圳证券交易所申请，公司股票自星期一开市起停牌，预计停牌时 间不超过2个交易日。 ...

11月2日，美国总统特朗普接受采访时表示，美军可能向尼日利亚派兵或发动空袭以制止恐怖分子实施 暴行。美国网民评论称"为什么特朗普想与之开战的国家全都是石油储量丰富的国家？"特朗普10月31日 在社交媒体上发文警告，尼日利亚政府迅速采取行动制止暴力。尼日利亚外交部1日发布声明指出，特 朗普的言论不符合实际情况。 ...

Core Points - The 40th Yanqing Ice and Snow Carnival is set to begin, featuring diverse ice and snow tourism products to cater to families, children, and professional players [1] - Yanqing has become a prominent ice and snow cultural tourism destination, especially after being one of the three competition zones for the 2022 Beijing Winter Olympics [1] - The event will include attractions such as winter ice lanterns at Longqing Gorge, snow-covered forests at Yudushan, and various ski trails at Shijinglong Ski Resort [1] - The local tourism bureau is focusing on enhancing the winter tourism experience by connecting with key tourism markets in the Pearl River Delta and Yangtze River Delta regions [1] - New "ice and snow + accommodation" services will provide visitors with an immersive winter vacation experience combining snow activities and warm lodging [1]

为持续深化援助效果，顺义区构建"评估-服务-跟踪-再评估"闭环机制，依托就业驿站和基层服务平台为 援助对象提供长期"就业陪跑"，通过动态管理档案实现定制化跟踪服务。 招聘会还设置了高校毕业生专区、重点行业专区等特色板块，对岗位进行标签化展示，方便求职者快速 匹配。本次活动共吸引127家企业参与，提供岗位3155个，现场初步达成就业意向1454人次，线上参与 1.7万人次。 新京报讯（记者耿子叶）顺义区近日举办2025年"金秋百企"专场招聘会，首次系统化运用分类分级就业 援助技术，构建"即时岗位匹配+短期能力提升+长期就业陪跑"的全流程服务体系，推动就业服务从"大 水漫灌"向"精准滴灌"转变。 招聘会现场设有"分类分级服务体验区"，职业指导师通过量表问卷从就业能力、心态和条件三个维度为 求职者精准画像，提供个性化指导。"一来就先做了测评，指导老师不仅帮我分析了优势短板，还结合 我的兴趣指出了适合的职业方向，让我对未来的规划清晰了很多。"求职者陈莹莹分享道。体验区内设 有简历修缮、面试模拟、职业指导等六大服务展台，运用AI工具快速优化简历、模拟面试，心理咨询 师与职业指导师协同提供心理调适与职业规划服务。此外，实 ...

Core Viewpoint - The announcement from the Ministry of Finance and the State Taxation Administration clarifies the tax policies related to gold transactions, particularly focusing on the exemption of value-added tax (VAT) for standard gold sales under specific conditions, effective from November 1, 2025, to December 31, 2027 [1][2]. Tax Policy Changes - The new policy states that when members or clients sell standard gold through the Shanghai Gold Exchange or the Shanghai Futures Exchange, they are exempt from VAT if no physical delivery occurs [2][3]. - The key change is the classification of standard gold based on its actual use, leading to different VAT treatments depending on whether the gold is for investment purposes or other uses [3][4]. Implications for Investors - For investment purposes, members purchasing standard gold will be subject to VAT "immediate collection and refund" policies, while direct sales or processing into investment gold products will incur VAT [3][4]. - Non-investment use of standard gold will be exempt from VAT, with ordinary invoices issued instead of VAT special invoices [3][5]. Market Impact - The announcement is seen as a response to the recent high gold prices and increased trading activity, with COMEX gold futures prices remaining above $4,000 per ounce [7][8]. - The policy may reduce the impact of informal gold circulation on prices and encourage institutional participation in the gold market [8]. Consumer Effects - The policy is expected to have minimal impact on individual consumers purchasing gold or gold jewelry, as the retail prices typically include VAT and consumption tax [9][11]. - However, if consumers purchase through dealers rather than directly from member units, they may face increased costs due to the changes in tax treatment [9][10].

Core Insights - The 17th New Oriental Family Education Forum focused on the theme "From Track to 'Field', Restructuring the Life Pattern of Children's Growth" to address the increasing psychological issues among adolescents and the role of family education in equipping children with necessary skills [1][5] Group 1: Psychological Health of Adolescents - Yu Minhong and Bi Shumin discussed the fragility of today's youth, questioning whether their struggles stem from personal choices or societal and educational pressures [2] - The "pipeline mentality" among parents, which emphasizes prestigious university admissions as the sole path to success, has led to children being squeezed into a narrow focus on academic performance, neglecting their hobbies and personal development [2] - Bi Shumin highlighted the importance of helping children find a sense of direction in an uncertain future, emphasizing the need for education to foster happiness and self-worth [2] Group 2: Family Education and Self-Acceptance - Zhao Dongmei shared her personal experience with her son dropping out of school, advocating for acceptance and support rather than shame for children facing educational challenges [3][4] - She emphasized the need for parents to reflect on their roles and the power dynamics in parent-child relationships, suggesting that societal pressures can exacerbate children's feelings of inadequacy [4] - The forum underscored the importance of distinguishing between "going to school" and "learning," promoting a more positive and individualized approach to education [4] Group 3: Educational Reform and Community Engagement - Experts at the forum discussed the necessity of raising awareness about family education, with Zhang Zhiyong stating that while love for children is instinctual, effectively loving them is a learned skill [4] - Lin Xiaoying provided a theoretical framework for understanding educational involution, emphasizing the need for interest-driven learning to foster genuine growth [4] - The forum aimed to provide rational support for educators and parents, promoting high-quality development in family education amidst rising anxiety [5]