Core Insights - Crystal Tech Holdings (02228) successfully executed a textbook "lightning placement," showcasing its strong market appeal and efficient execution in capital markets [1] - The company raised HKD 2.65 billion through the placement of approximately 286 million shares, with a placement price of HKD 9.28 per share, reflecting a premium of about 75.8% over the IPO price and 23.4% over the average closing price of the last 30 trading days [1] - The placement attracted significant interest from various institutional investors, including the world's largest sovereign fund, Norges Bank Investment Management, indicating strong confidence in the company's growth prospects [2] Financial Performance - In the first half of 2025, Crystal Tech Holdings achieved its first large-scale profitability, with revenue from drug discovery solutions increasing by 615.2% to HKD 435 million, and revenue from intelligent robotics solutions rising by 95.9% to HKD 82 million [2] - As of August 27, the company's market capitalization exceeded HKD 41.2 billion, making it the highest-valued company in the Asian AI drug discovery sector [2] Cash Reserves - As of June 30, 2025, the company held cash reserves of HKD 5.308 billion, and with the new financing, total cash reserves are approximately HKD 8 billion, providing a strong financial foundation for continued leadership in the field [3] Innovation and Future Plans - The company plans to utilize the funds from the placement for product and research iteration, commercialization expansion, and potential mergers and acquisitions, while also exploring innovative financial tools such as RWA (Real World Assets) and RDA (Real Data Assets) [1][4] - The recent launch of the RWA registration platform in Hong Kong aligns with the company's strategy to digitize real-world assets, enhancing liquidity and broadening financing channels for innovative drug development [4]

Core Insights - Jingtai Holdings (02228) demonstrated strong market appeal and execution capability through a textbook "lightning placement" by announcing a placement of up to approximately 286 million shares, raising HKD 2.65 billion [1] - The placement price was set at HKD 9.28 per share, representing a premium of approximately 75.8% over the IPO price and about 23.4% over the average closing price of the last 30 trading days, indicating high market recognition of the company's value [1] - The placement attracted significant interest from various institutional investors, including Norges Bank Investment Management, the world's largest sovereign wealth fund, reflecting strong confidence in the company's growth prospects [2] Financial Performance - In the first half of 2025, Jingtai Holdings achieved scale profitability for the first time, with revenue from drug discovery solutions increasing by 615.2% to HKD 435 million, and revenue from intelligent robotics solutions rising by 95.9% to HKD 82 million [2] - As of August 27, 2025, the company's market capitalization exceeded HKD 41.2 billion, making it the highest-valued company in the Asian AI drug discovery sector [2] - The company has a robust cash reserve of HKD 5.308 billion as of June 30, 2025, which, combined with the new financing, brings total cash reserves to approximately HKD 8 billion, providing a strong financial foundation for continued leadership in the field [3] Strategic Initiatives - Jingtai Holdings plans to utilize the proceeds from the placement for product and research iteration, commercialization expansion, and potential mergers and acquisitions, while also exploring innovative financial tools such as RWA (Real World Assets) and RDA (Real Data Assets) [1][4] - The company’s AI and robotics molecular discovery platform aligns well with the newly launched RWA registration platform in Hong Kong, which aims to facilitate the tokenization of real-world assets, enhancing asset liquidity and broadening financing channels for innovative drug development [4]

Group 1: Industry Overview - SandboxAQ, an AI startup supported by Alphabet and Nvidia, launched a large-scale synthetic dataset to accelerate global drug development by simulating drug molecule and protein interactions [1] - Major pharmaceutical companies like Merck, Pfizer, Eli Lilly, and BMS have invested hundreds of billions in AI drug-related companies, indicating a strong demand for AI-assisted drug development [1] - The total value of significant AI drug development transactions has exceeded $50 billion in the last five years, highlighting the growing interest and investment in this sector [1] Group 2: Company Developments - Crystal Tech Holdings expects to achieve a consolidated revenue of at least RMB 500 million by mid-2025, a year-on-year increase of approximately 387%, driven by a partnership with DoveTree Medicines [3] - Via Biotechnology has seen AI-related orders account for 12% of new signed orders, indicating a growing trend in AI integration within their drug development processes [3] - Via is transitioning from a focus on computational methods to AI-driven drug design, aiming to change the paradigm of drug design [3] Group 3: Market Trends - AI pharmaceutical companies are increasingly securing large orders from multinational corporations, validating the profitability of AI drug development through technology licensing and revenue-sharing models [2] - The first approved AI-driven drug is anticipated to be a significant milestone, with both AI companies and traditional pharmaceutical leaders competing for breakthroughs in this new field [2] - The entry of various players, including cross-industry companies, into the AI drug development space is expected to enhance competitive barriers over time [2]

Core Viewpoint - Jingtai Holdings (02228) announced a placement agreement to issue up to approximately 286 million placement shares at HKD 9.28 per share, aiming to raise approximately HKD 2.63 billion for various strategic initiatives [1] Group 1: Fundraising Details - The company plans to issue up to approximately 286 million shares through a placement agent [1] - Each placement share is priced at HKD 9.28, with total net proceeds expected to be around HKD 2.63 billion if fully subscribed [1] Group 2: Use of Proceeds - The raised funds will be utilized for continuous product iteration and upgrading, enhancing research and development capabilities, and solution capabilities [1] - The company aims to commercialize products and develop business by strengthening collaborations with external parties in similar and mutually beneficial industries [1] - Additional uses include potential acquisitions and investments, talent attraction and recruitment, working capital replenishment, and general corporate purposes [1]

Core Viewpoint - Crystal Tech Holdings (02228) announced a placement agreement to issue up to approximately 286 million shares at a price of HKD 9.28 per share, aiming to raise approximately HKD 2.63 billion for various strategic initiatives [1] Group 1: Fundraising Purpose - The net proceeds from the share placement are intended for continuous product iteration and upgrading, enhancing research and development capabilities, and solution capabilities [1] - The funds will also support product commercialization and business development, strengthening collaborations with external parties and partners in similar and mutually beneficial industries [1] - Additional uses of the funds include potential acquisitions and investments, talent attraction and recruitment, working capital replenishment, and general corporate purposes [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確 性或完整性亦不發表任何聲明，並明確表示，概不對因本公告全部或任何部分內容而產生或 因倚賴該等內容而引致的任何損失承擔任何責任。 本公告僅供參考用途，並不構成收購、購買或認購本公司證券的邀請或要約。 本公告或其任何副本概不得直接或間接在美國，或在刊發或派發本公告屬違法的任何其他司 法權區內刊發或派發。 本公告並非構成或組成於美國境內購買或認購證券的任何要約或購買或認購證券的招攬的 一部分。本公告所述證券並未亦不會根據證券法登記，亦不得在美國境內提呈發售或出售， 惟根據證券法的登記規定獲豁免或不受證券法登記規定規限的交易除外。本公司無意根據證 券法登記本公告所指之任何證券，或在美國進行證券的公開發售。 XtalPi Holdings Limited （ 於 開 曼 群 島 註 冊 成 立 之 有 限 公 司 ） 晶泰控股有限公司 （股份代號：2228） 根據一般授權配售新股份 聯席整體協調人 （按英文字母順序排序） 聯席賬簿管理人 （排名不分先後） – 1 – 董事會欣然宣佈，於2025年8月29日（交易時段前），本公司與配售代理訂 ...

Investment Rating - The report provides an investment rating of "Outperform" for XtalPi Holdings, indicating an expected total return exceeding the relevant market benchmark over the next 12-18 months [17]. Core Insights - XtalPi Holdings reported a significant revenue increase of RMB 517 million for H1 2025, a year-on-year growth of 403.8%, and achieved an adjusted net profit of RMB 142 million, marking its first half-year profit [6][7]. - The company has a strong cash position with a cash balance of RMB 5.308 billion and a 20% reduction in monthly average cash burn to RMB 49.7 million, reflecting improved financial health [6][7]. - Future growth is anticipated due to the progress in collaboration with DoveTree Medicines and the scaling of its AI technology platform [6][7]. Summary by Sections Revenue and Profitability - The drug discovery solutions segment became the largest growth driver, generating RMB 435 million in revenue, a staggering increase of 615.2% year-on-year, accounting for 84% of total revenue [9][10]. - The intelligent robotics solutions segment also showed strong performance, achieving revenue of RMB 81.86 million, a 95.9% increase year-on-year, driven by demand for automated chemical synthesis services and increased penetration of XtaPi R&D solutions [10] [3]. R&D Investment and Technological Advancements - R&D expenditure increased by 5.3% year-on-year to RMB 222 million, supporting technological breakthroughs and the expansion of the R&D team [8]. - The implementation of the end-to-end AI drug discovery platform and the "AI + Robotics" technology matrix has significantly enhanced internal R&D efficiency and serves as a core competitive advantage for external services [8][9]. Key Collaborations and Orders - The company achieved a major milestone in its collaboration with DoveTree Medicines, receiving an initial payment of USD 51 million, which directly contributed to the explosive growth of its drug discovery solutions business [7][9]. - The order volume for intelligent robotics solutions increased significantly, indicating a robust order reserve across diversified business lines [7].

Group 1 - On August 28, 2025, the top three companies by trading volume in the Hong Kong Stock Connect (southbound) were SMIC (00981) with a trading volume of 11.618 billion, Meituan-W (03690) with 9.659 billion, and the Tracker Fund of Hong Kong (02800) with 7.940 billion [1][2] - In the Shenzhen-Hong Kong Stock Connect (southbound), the top three companies were Meituan-W (03690) with a trading volume of 6.145 billion, SMIC (00981) with 5.565 billion, and Alibaba-W (09988) with 4.726 billion [1][2] Group 2 - In the Hong Kong Stock Connect (southbound), the net buying amounts for the top three companies were SMIC (00981) with +0.575 billion, Meituan-W (03690) with +0.630 billion, and Alibaba-W (09988) with +0.706 billion [2] - The Tracker Fund of Hong Kong (02800) had a significant net outflow of -7.885 billion, indicating a strong selling pressure [2] - In the Shenzhen-Hong Kong Stock Connect (southbound), Meituan-W (03690) experienced a net outflow of -0.297 billion, while SMIC (00981) had a net inflow of +0.318 billion [2]

Summary of Key Points Core Viewpoint - The Hong Kong stock market experienced significant net selling from northbound capital, with a total net sell of 204.41 billion HKD on August 28, 2023, indicating a cautious sentiment among investors [1]. Group 1: Northbound Capital Activity - Northbound capital saw a net sell of 132.97 billion HKD through the Shanghai Stock Connect and 71.44 billion HKD through the Shenzhen Stock Connect [1]. - The most bought stocks included SMIC (00981), Kangfang Biotech (09926), and Huahong Semiconductor (01347), while the most sold stocks were the Tracker Fund of Hong Kong (02800), Hang Seng China Enterprises Index (02828), and Tencent (00700) [1]. Group 2: Stock Performance and Predictions - SMIC received a net buy of 8.92 billion HKD, while Huahong Semiconductor had a net buy of 4.63 billion HKD, reflecting a renewed interest in chip stocks [6]. - Kangfang Biotech saw a net buy of 5.11 billion HKD, supported by positive clinical trial results for its drug [6]. - China Life (02628) received a net buy of 3.83 billion HKD, with expectations of steady growth in profits and new business value (NBV) [7]. Group 3: Sector Trends and Market Sentiment - The technology sector showed mixed results, with Meituan (03690) and Alibaba (09988) receiving net buys of 3.33 billion HKD and 3.29 billion HKD, respectively, while Tencent faced a net sell of 5.83 billion HKD [7]. - The AI sector is expected to be a key driver for Hong Kong tech stocks, with improved market sentiment due to easing trade tensions between China and the U.S. [7]. - Horizon Robotics (09660) reported a revenue increase of 67.6% year-on-year, indicating strong growth in the autonomous driving market [8]. Group 4: ETF and Fund Flows - Northbound capital also sold off ETFs, with the Tracker Fund of Hong Kong (02800) and Hang Seng China Enterprises Index (02828) facing net sells of 118.86 billion HKD and 47.76 billion HKD, respectively [9]. - Despite the selling pressure, there is an expectation for continued foreign capital inflow into the Chinese market, although the importance of foreign capital in the Hong Kong market has decreased [9].

Core Viewpoint - Jingtai Holdings (02228.HK) achieved its first half-year profit since its listing, marking a significant milestone and indicating a new growth phase for the company, laying a solid foundation for its future strategic plans [3]. Financial Performance - For the first half of 2025, the company reported revenue of 5,307.7 million yuan, representing a year-on-year increase of 403.8% [4]. - The adjusted net profit for the same period was 141.6 million yuan [4]. Business Review - The drug discovery solutions segment saw a remarkable revenue increase of 615.2%, driven by significant collaborations and milestone achievements [6]. - A major collaboration with biopharmaceutical legend Gregory Verdine resulted in an initial payment of $51 million and potential milestone payments totaling $5.89 billion [7]. - The antibody business experienced substantial growth, achieving nearly double the revenue of the entire previous year in the first half of 2025 [12]. Technological Advancements - The company has developed the AI-driven drug discovery platform XtalFold®, which has been upgraded to enhance its performance in complex biomolecular modeling [15]. - The AI capabilities have been continuously upgraded, with over 200 AI models developed for various applications in drug discovery [14]. Strategic Collaborations - The company signed multi-million dollar agreements with JW Pharmaceutical and other leading firms to provide comprehensive automation and AI-driven solutions for drug candidate screening and synthesis [22][23]. - A significant partnership with Roche was established to automate molecular sorting and storage processes [24]. Innovations in Robotics - The company introduced a new generation of modular robots equipped with patented flexible gripping devices, enhancing operational flexibility and efficiency in chemical research [21]. - The Multi-Agent system is being deployed to streamline the entire chemical synthesis process, significantly improving throughput and data accumulation efficiency [39].