Group 1 - The core viewpoint of the news is that Zhaoyan New Drug has seen a significant increase in its stock price, rising by 5.32% to reach 36.25 yuan per share, with a trading volume of 1.357 billion yuan and a turnover rate of 6.15%, resulting in a total market capitalization of 27.169 billion yuan [1] - Zhaoyan New Drug Research Center Co., Ltd. is primarily engaged in non-clinical safety evaluation services for drugs and the sale of preclinical research services and laboratory animals, established on February 25, 1998, and listed on August 25, 2017 [1] Group 2 - According to data from the top ten heavy stocks of funds, Guojin Fund has a significant holding in Zhaoyan New Drug, with the Guojin Xinyi Medical Consumption A fund holding 256,000 shares, accounting for 4.07% of the fund's net value, ranking as the eighth largest heavy stock [2] - The Guojin Xinyi Medical Consumption A fund, established on June 30, 2020, has a latest scale of 32.205 million yuan, with a year-to-date return of 20.05% and a one-year return of 27.2% [2] - The fund manager, Zhang Wang, has been in position for 5 years and 178 days, with the fund's total asset scale at 360 million yuan, achieving the best return of 47.64% and the worst return of -12.63% during his tenure [2]

Core Viewpoint - Zhaoyan New Drug has shown significant stock price growth in 2023, with a year-to-date increase of 111.57% and a recent market capitalization of 26.322 billion yuan [1] Group 1: Stock Performance - As of September 12, Zhaoyan New Drug's stock price reached 35.12 yuan per share, with a trading volume of 7.81 billion yuan and a turnover rate of 3.58% [1] - The stock has experienced a 3.26% increase over the last five trading days, a 6.55% increase over the last 20 days, and an 87.91% increase over the last 60 days [1] - The company has appeared on the "Dragon and Tiger List" twice this year, with the most recent occurrence on July 29 [1] Group 2: Financial Performance - For the first half of 2025, Zhaoyan New Drug reported a revenue of 669 million yuan, a year-on-year decrease of 21.28%, while the net profit attributable to shareholders increased by 135.90% to 60.9324 million yuan [2] - Since its A-share listing, the company has distributed a total of 703 million yuan in dividends, with 356 million yuan distributed over the past three years [3] Group 3: Shareholder Structure - As of June 30, 2025, the number of shareholders increased by 25.59% to 61,200 [2] - The top five circulating shareholders include Huabao Zhongzheng Medical ETF, which increased its holdings by 2.2669 million shares, and Hong Kong Central Clearing Limited, which reduced its holdings by 943,870 shares [3]

Market Overview - The Shanghai Composite Index rose by 1.65% on September 11, with 31 out of 41 sectors experiencing gains, led by the communication and electronics sectors, which increased by 7.39% and 5.96% respectively [2] - The pharmaceutical and biotechnology sector saw a modest increase of 0.25% [2] Capital Flow Analysis - The net inflow of capital in the two markets reached 34.518 billion yuan, with 11 sectors experiencing net inflows [2] - The electronics sector had the highest net inflow of 21.723 billion yuan, corresponding to its 5.96% increase, followed by the computer sector with a net inflow of 8.479 billion yuan and a daily increase of 3.71% [2] Pharmaceutical and Biotechnology Sector Performance - Within the pharmaceutical and biotechnology sector, there were 474 stocks, with 350 stocks rising and 111 stocks declining [3] - The top three stocks with the highest net inflow were Jimin Health (2.37 billion yuan), Shutai Shen (1.55 billion yuan), and Rejing Bio (1.41 billion yuan) [3] - The sector experienced a net outflow of 3.975 billion yuan, with the largest outflows from WuXi AppTec (3.17 billion yuan), BeiGene (2.29 billion yuan), and Zhaoyan New Drug (1.78 billion yuan) [3][5] Top Gainers in Pharmaceutical Sector - The top gainers in the pharmaceutical sector included: - Jimin Health: +10.02% with a turnover rate of 16.96% and a capital flow of 236.996 million yuan - Shutai Shen: +7.24% with a turnover rate of 10.87% and a capital flow of 155.111 million yuan - Rejing Bio: +11.40% with a turnover rate of 6.65% and a capital flow of 140.912 million yuan [4] Top Losers in Pharmaceutical Sector - The top losers in the pharmaceutical sector included: - WuXi AppTec: -2.41% with a turnover rate of 4.06% and a capital outflow of -317.3795 million yuan - BeiGene: -3.73% with a turnover rate of 11.42% and a capital outflow of -229.1395 million yuan - Zhaoyan New Drug: -2.88% with a turnover rate of 9.44% and a capital outflow of -178.0592 million yuan [5]

Market Performance - Major market indices opened with mixed results, with the Shanghai Composite Index down 0.16% at 3806.06 points, the Shenzhen Component Index up 0.11% at 12570.87 points, and the ChiNext Index up 0.46% at 2917.77 points [1] Individual Stock Performance - A total of 1482 stocks rose at the opening, with 7 stocks hitting the daily limit up. Notable performers included *ST Weier with 13 consecutive limit ups, Qingshan Paper with 8 consecutive limit ups, and *ST Yatai with 4 consecutive limit ups [1] - Conversely, 3048 stocks declined at the opening, with 6 stocks hitting the daily limit down, including Youzu Network and Huaguang Huaneng [1] Continuity of Stock Prices - Among the stocks that hit the limit up yesterday, those that continued to hit the limit up today included Qingshan Paper and Xinju Network, among others [1] - Stocks that opened lower included Hezhan Energy, Sijuan New Materials, and Zhaoyan New Drug, with opening declines of 9.89%, 4.91%, and 4.37% respectively [1] - Among the stocks that hit the limit down yesterday, *ST Yuancheng and *ST Gaohong continued to hit the limit down today [1]

Group 1 - The A-share CRO sector experienced a decline, with major companies like WuXi AppTec and Tigermed dropping over 7% [1] - Kanglong Chemical fell by more than 5%, while other firms such as Zhaoyan New Drug, Mediso, and Hengrui Medicine also saw declines [1]

Investment Rating - The industry investment rating is optimistic [2] Core Views - The report indicates a recovery in the industry, marking a turning point for allocation strategies [6] - The financial data and order trends suggest that the CXO sector has reached a fundamental turning point and is in a phase of continuous recovery [63] Summary by Sections Stock Price Review - Domestic performance shows a significant increase in the medical research outsourcing index, which rose by 60.41% from December 31, 2024, to September 4, 2025, outperforming the pharmaceutical and biotechnology index by 36.15 percentage points [4] - Internationally, there is a general upward revision of performance forecasts, with signs of demand recovery. Medpace showed the largest upward adjustment in its 2025 guidance [4][17] Financial Analysis - Growth: The year-over-year (YOY) revenue trend is improving, with the average YOY revenue growth for CXO companies reaching 8.2% in Q1 2025 and 11.6% in Q2 2025 [26] - Profitability: The average gross margin in Q2 2025 was 32.45%, showing a slight increase of 0.18 percentage points YOY. Some companies like Medpace and Boten Co. saw significant improvements in their margins [33] - Operational Efficiency: Inventory turnover improved from 1.56 in H1 2024 to 1.81 in H1 2025, indicating enhanced operational efficiency driven by increased capacity utilization [35] Thoughts and Outlook - PE/VC financing in the healthcare sector has stabilized at a low point, with a slight decline in absolute values for Q2 2025 compared to previous quarters, but ongoing improvements in global IPOs and business development transactions are expected to drive demand recovery [47] - IPO financing in the A-share and US markets has stabilized, while Hong Kong's market has seen a significant rebound, with HK IPO amounts reaching 20.7 billion HKD in 2025 [52] - The construction of new projects remains high, indicating optimistic expectations for capacity expansion among CXO companies, with a focus on new business areas such as ADCs and oligonucleotides [56] Investment Strategy - The report recommends investing in CDMO opportunities driven by the continued realization of commercial orders for small and large molecules, as well as clinical CRO opportunities supported by domestic innovation drug policies [63] - Key companies to watch include WuXi AppTec, Kelun Pharmaceutical, and others in the small molecule and large molecule CDMO sectors [63]

Market Overview - The medical services sector increased by 1.22% on September 10, with Meidisi leading the gains [1] - The Shanghai Composite Index closed at 3812.22, up 0.13%, while the Shenzhen Component Index closed at 12557.68, up 0.38% [1] Top Gainers in Medical Services - Meidisi (688202) closed at 75.91, up 14.36% with a trading volume of 172,900 shares and a turnover of 1.262 billion yuan [1] - Zhaoyan New Drug (603127) closed at 35.44, up 9.99% with a trading volume of 710,100 shares and a turnover of 2.481 billion yuan [1] - Bid Medicine (688073) closed at 67.40, up 7.72% with a trading volume of 23,600 shares and a turnover of 156 million yuan [1] - Other notable gainers include Pusens (301257), Nuohezhiyuan (688315), and Haoyuan Medicine (688131) with respective increases of 7.07%, 6.12%, and 5.81% [1] Market Capital Flow - The medical services sector saw a net inflow of 523 million yuan from institutional investors, while retail investors experienced a net outflow of 179 million yuan [2] - The top stocks by net inflow from institutional investors include Zhaoyan New Drug with 481 million yuan and YaoMingKangDe with 106 million yuan [3] Notable Decliners - Nanmo Biology (688265) decreased by 4.09% to 54.64 with a trading volume of 13,800 shares and a turnover of 76.751 million yuan [2] - Zihua Medicine (600721) fell by 3.25% to 9.82 with a trading volume of 479,100 shares and a turnover of 476 million yuan [2] - Other decliners include Haitai Biology (300683) and Huada Muyin (300676) with respective declines of 2.50% and 2.17% [2]

9月10日早盘，医疗板块低开后快速回暖，CXO概念强劲反弹，昭衍新药涨停，康龙化成涨超5%，巨 头药明康德涨超2%。 消息面上，Grand View Research预测，全球CXO市场规模有望从2024年的1970亿美元增长至2030年的 2980亿美元，期间年复合增速为7%，略高于同期全球制药市场6%的年复合增速。 从估值来看，医疗ETF（512170）标的指数中证医疗最新PE估值约为36倍，仍低于近10年逾60%时间区 间，配置性价比相对突出。 牛市"高切低"，关注医疗估值洼地。配置工具认准A股最大医疗ETF（512170）及其联接基金 （012323）：聚焦"医疗器械（52%）+医疗服务（40%）"，与AI医疗高相关，覆盖6只CXO龙头股。截 至9月8日，医疗ETF（512170）规模275亿元，同类规模最大；年初以来日均成交6.45亿元，流动性优 秀。 风险提示：医疗 ETF 及其联接基金被动跟踪中证医疗指数，该指数基日为 2004.12.31 ，发布于 2014.10.31 。 中 证 医 疗 指 数 2020 年 至 2024 年 的 分 年 度 业 绩 分 别 为 79.67% 、 -14.7 ...

Core Viewpoint - The innovative drug concept stocks are experiencing significant activity, with notable gains in several companies, indicating a positive trend in the pharmaceutical sector [1] Company Summaries - Zhaoyan New Drug has reached its daily limit increase, reflecting strong investor interest and confidence in its growth potential [1] - MediXis, Kanglong Chemical, Haixiang Pharmaceutical, Kailaiying, and Jiuzhou Pharmaceutical have also seen upward movement in their stock prices, suggesting a broader rally in the innovative drug sector [1]

证券之星消息，9月9日医疗服务板块较上一交易日下跌2.94%，昭衍新药领跌。当日上证指数报收于 3807.29，下跌0.51%。深证成指报收于12510.6，下跌1.23%。医疗服务板块个股涨跌见下表： 从资金流向上来看，当日医疗服务板块主力资金净流出17.25亿元，游资资金净流入4.63亿元，散户资金 净流入12.62亿元。医疗服务板块个股资金流向见下表： 以上内容为证券之星据公开信息整理，由AI算法生成（网信算备310104345710301240019号），不构成投资建议。 | 代码 | 名称 | 收盘价 | 涨跌幅 | 成交量(手) | 成交额(元) | | --- | --- | --- | --- | --- | --- | | 603127 | 昭衍新药 | 32.22 | -7.01% | 47.36万 | 15.66亿 | | 688222 | 成都先导 | 25.13 | -6.79% | 25.48万 | 6.60亿 | | 835670 | 数字人 | 17.97 | -6.60% | 9.56万 | 1.76亿 | | 002173 | 创新医疗 | 22.49 | -5.74% | ...