Key Points - *ST Zhengping's stock will resume trading on November 12, 2025, after a significant increase of 152.42% from September 1 to October 28, 2025, with 21 days of trading halts and 5 instances of abnormal trading fluctuations [3] - Dongfang Zhizao plans to acquire 70% of Nantong Saifu Machinery Equipment Co., Ltd. for 27.4887 million yuan, making it a subsidiary [4] - Zhifei Biology received approval for clinical trials of a combined vaccine for adolescents and adults to prevent diphtheria, tetanus, and whooping cough [5] - CITIC Securities has been approved by the CSRC to issue up to 50 billion yuan in short-term corporate bonds [6] - Bangji Technology intends to terminate a major asset restructuring involving the acquisition of several companies, stating that current operations will not be adversely affected [7] - Dekeli is planning to issue S-shares and list on the Singapore Exchange as part of its global strategy [8] - Emei Mountain A announced that Leshan State Investment will transfer 90% of its stake in Emei Mountain Leshan Buddha Tourism Group to another state-owned entity without compensation, maintaining the current control structure [9] Performance Summary - Xincheng Development reported a contract sales amount of approximately 1.419 billion yuan in October 2025, with cumulative sales of about 16.468 billion yuan from January to October [11] - Huadong Holdings sold 242,500 pigs in October 2025, with a 19.85% month-on-month increase and a 20.80% year-on-year increase [13] - Xiamen Airport's passenger throughput in October was 2.5548 million, a year-on-year increase of 1.56% [14] Shareholding Changes - Huaguang Huaneng executives plan to reduce their holdings, with the chairman and several executives intending to sell up to 171,200 shares each [16] - Hot景 Biology announced a share buyback plan of 100 million to 200 million yuan for employee stock ownership or incentives [17] - Aladdin's controlling shareholder's stake decreased from 46.27% to 44.76% due to the dissolution of a partnership [18] - JianKai Technology's controlling shareholder plans to transfer 3% of the company's shares [19] - Yuyuan Holdings intends to repurchase shares worth 200 million to 300 million yuan at a price not exceeding 8.6 yuan per share [20] Major Contracts - China Oil Engineering's subsidiary won a project in Kazakhstan worth approximately 3.003 billion yuan for the construction of ethane and propane pipelines [22] - Dash Intelligent signed a contract for an intelligent display technology park project worth 12.7652 million yuan, which will positively impact its market share in the enterprise park sector [24]

Core Viewpoint - Zhifei Biological's subsidiary has received approval for clinical trials of a new vaccine aimed at preventing infectious diseases caused by diphtheria, tetanus, and whooping cough [1] Group 1 - Zhifei Biological announced that its wholly-owned subsidiary, Beijing Zhifei Lvzhu Biological Pharmaceutical Co., Ltd., has obtained the clinical trial approval notice from the National Medical Products Administration [1] - The vaccine is an adsorbed acellular diphtheria, tetanus, and pertussis (DTPa) combined vaccine intended for adults and adolescents [1] - The clinical trials will focus on preventing infections caused by diphtheria, tetanus, and whooping cough [1]

Core Viewpoint - The company announced that its wholly-owned subsidiary, Beijing Zhifei Lvzhu Biological Pharmaceutical Co., Ltd., has received approval from the National Medical Products Administration for clinical trials of an acellular combined vaccine for adults and adolescents, aimed at preventing infections caused by diphtheria, tetanus, and whooping cough [1] Group 1 - The vaccine is designed to prevent infectious diseases caused by diphtheria, tetanus, and whooping cough [1] - The approval allows the company to initiate clinical trials for the vaccine [1]

Group 1 - The core point of the article is that Zhifei Biological (SZ 300122) has received approval from the National Medical Products Administration for clinical trials of its acellular combined vaccine for diphtheria, tetanus, and pertussis aimed at adolescents and adults [1] - Zhifei Biological's revenue composition for the year 2024 is projected to be 99.14% from biological products and 0.86% from other businesses [1] - As of the report, Zhifei Biological has a market capitalization of 52.1 billion yuan [1] Group 2 - The chairman of Peking University Pharmaceutical, Xu Xiren, was investigated by the police prior to his arrest, with reports indicating that the group's assets were disposed of and large sums of money are unaccounted for [1]

智通财经APP讯，智飞生物(300122.SZ)发布公告，公司于近日获悉，由全资子公司北京智飞绿竹生物制 药有限公司(简称"智飞绿竹")研发的吸附无细胞百白破(组分)联合疫苗(成人及青少年用)(简称"青少年及 成人组分百白破疫苗")获得国家药品监督管理局药物临床试验批准通知书(通知书编号： 2025LP02971)，同意开展预防白喉、破伤风、百日咳引起的感染性疾病的临床试验。公司将根据临床试 验批准通知书的要求，尽快开展相关临床试验工作。 ...

证券代码：300122 证券简称：智飞生物 公告编号：2025-66 重庆智飞生物制品股份有限公司 关于吸附无细胞百白破（组分）联合疫苗（成人及青少年用） 获得临床试验批准通知书的公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚 假记载、误导性陈述或重大遗漏。 重庆智飞生物制品股份有限公司（以下简称"公司"）于近日获悉，由全资 子公司北京智飞绿竹生物制药有限公司（以下简称"智飞绿竹"）研发的吸附无 细胞百白破（组分）联合疫苗（成人及青少年用）（以下简称"青少年及成人组 分百白破疫苗"）获得国家药品监督管理局药物临床试验批准通知书（通知书编 号：2025LP02971），同意开展预防白喉、破伤风、百日咳引起的感染性疾病的 临床试验。公司将根据临床试验批准通知书的要求，尽快开展相关临床试验工作。 一、研发项目简介 百日咳是由百日咳杆菌引起的一种传染性极强的急性呼吸系统疾病。百日咳 在我国一年四季均可发病，春夏季发病较多，农村发病率高于城市。白喉是由白 喉杆菌所引起的一种急性呼吸道传染病，以发热，气憋，声音嘶哑，咳嗽，咽、 扁桃体及其周围组织出现白色伪膜为特征，发病无明显的季节性。破伤风通常是 ...

Market Overview - The biopharmaceutical sector experienced a slight decline of 0.08% on November 11, with He Yuan Bio leading the drop [1] - The Shanghai Composite Index closed at 4002.76, down 0.39%, while the Shenzhen Component Index closed at 13289.0, down 1.03% [1] Stock Performance - Notable gainers included: - Jin Ke (688670) with a closing price of 24.97, up 19.99% on a trading volume of 134,300 shares and a transaction value of 310 million [1] - Kanghua Bio (300841) closed at 83.21, up 6.04% with a trading volume of 57,100 shares [1] - Watson Bio (300142) closed at 12.82, up 2.64% with a trading volume of 942,000 shares [1] - Significant losers included: - Bu Yuan Bio (688765) closed at 86.00, down 8.02% with a trading volume of 107,600 shares [2] - Ao Pu Mai (688293) closed at 59.18, down 3.65% with a trading volume of 17,900 shares [2] - Rongchang Bio (688331) closed at 86.00, down 2.55% with a trading volume of 45,900 shares [2] Capital Flow - The biopharmaceutical sector saw a net outflow of 671 million from institutional investors, while retail investors contributed a net inflow of 335 million [2] - The capital flow for key stocks showed: - Jin Ke had a net inflow of 48.11 million from institutional investors, but a net outflow of 24.49 million from speculative funds [3] - Zhifei Bio (300122) experienced a net inflow of 15.25 million from institutional investors, with a net outflow of 23.20 million from retail investors [3] - Kanghua Bio had a net inflow of 14.35 million from institutional investors, but a net outflow of 23.26 million from speculative funds [3]

Core Viewpoint - The stock of Zhifei Biological has shown fluctuations, with a recent increase of 2.04% but a year-to-date decline of 16.50%, indicating potential volatility in the market [1][2]. Company Overview - Zhifei Biological, established on July 20, 1995, and listed on September 28, 2010, is located in Chongqing and specializes in the research, production, and sales of vaccines and biological products [1]. - The company's revenue composition includes 88.84% from agency products, 10.15% from self-developed products, and 1.00% from other sources [1]. Financial Performance - For the period from January to September 2025, Zhifei Biological reported a revenue of 76.27 billion, a year-on-year decrease of 66.53%, and a net profit attributable to shareholders of -12.06 billion, reflecting a significant decline of 156.10% [2]. - Cumulatively, the company has distributed 73.18 billion in dividends since its A-share listing, with 31.94 billion distributed over the last three years [3]. Shareholder Information - As of September 30, 2025, the number of shareholders for Zhifei Biological is 131,600, a decrease of 3.17% from the previous period, with an average of 10,750 circulating shares per shareholder, an increase of 3.28% [2]. - The top ten circulating shareholders include significant institutional investors, with notable reductions in holdings for several funds, indicating potential shifts in investor sentiment [3].

Group 1 - The vaccine sector experienced a significant rise, with Gendik hitting the daily limit increase [1] - Other companies such as Watson Bio, Zhifei Bio, Kangtai Bio, Baike Bio, and Kangle Weishi also saw gains [1]

Market Performance - The market experienced a volatile upward trend last week, with the Shanghai Composite Index rising by 1.08%, the Shenzhen Component Index by 0.19%, and the ChiNext Index by 0.65% [2] - The China Securities Index reported a decrease of 0.40%, closing at 2021.77 points [2] Strong Stock Performances - Notable strong performers included Zhongwei Company, which increased by 10.66%, and Darentang, which rose by 8.80% [2] - Other significant gainers were Yangguang Electric Power and Yiwei Lithium Energy, with increases of 5.90% and 5.04% respectively [2] Year-to-Date Stock Gains - Since the beginning of the second half of the year, Zhongji Xuchuang has surged by 236.32%, leading the gains [3] - Yangguang Electric Power follows with a rise of 198.52%, while Yiwei Lithium Energy, Zhaoyi Innovation, and Zhongwei Company have increased by 91.34%, 75.11%, and 69.86% respectively [3] Market Outlook - Short-term market sentiment is expected to remain volatile, with basic economic factors potentially having a reduced impact on stock structure [4] - Long-term perspectives suggest that the current market risk premium is at a historical median level, with equity asset valuations remaining reasonable [4] - The market is anticipated to shift from valuation-driven growth to fundamental-driven growth as domestic economic stability improves [4] Investment Focus - Investment strategies should focus on sectors with structural growth potential, particularly in emerging growth areas such as AI technology innovation, energy infrastructure, and semiconductors [4] - Additionally, attention should be given to cyclical sectors that may benefit from "anti-involution" policies and leading companies actively expanding into overseas markets [4]