Core Viewpoint - The article highlights the contrasting performance and business strategies of two A-share pharmaceutical companies, Shuyou Shen (舒泰神) and Zhaoyan New Drug (昭衍新药), both led by the same entrepreneurial couple, Feng Yuxia and Zhou Zhiwen. While Shuyou Shen focuses on innovative drug development and is currently facing losses, Zhaoyan New Drug, which provides CRO services, has shown consistent profitability but is experiencing market fluctuations related to its key resource, experimental monkeys [1][2][3]. Company Performance - Shuyou Shen's stock price surged over 700% from May to August, making it a standout in the pharmaceutical sector, while Zhaoyan New Drug's stock price doubled within the same timeframe [2]. - As of September 26, Shuyou Shen's stock was priced at 33.87 CNY, reflecting a year-to-date increase of 357.09%, while Zhaoyan New Drug's stock was at 36.93 CNY, with a 115.7% increase [3]. - Both companies have seen a decline in stock prices from their peak, with Shuyou Shen experiencing a 39.03% drop from August 19 to September 26, and Zhaoyan New Drug seeing a 12.49% decrease from September 17 to 26 [4]. Financial Results - Shuyou Shen reported a revenue of approximately 126 million CNY for the first half of the year, a 31.14% decrease year-on-year, and a net loss of 25 million CNY, down 619.7% [6]. - In contrast, Zhaoyan New Drug achieved a revenue of about 669 million CNY, a 21.28% decline, but turned a profit with a net income of 61 million CNY, marking a recovery from previous losses [7]. Market Dynamics - Zhaoyan New Drug's performance is closely tied to the market price of experimental monkeys, which are essential for drug research. The company benefits from stable supply and demand, which helps maintain monkey prices [8]. - The company has indicated that new orders are increasing, providing a positive outlook for future revenue and profit recovery, despite current challenges [7]. Future Outlook - Shuyou Shen's future growth hinges on the successful commercialization of its innovative drug STSP-0601 for hemophilia, which has been prioritized for review, creating significant market expectations [9]. - Zhaoyan New Drug faces long-term challenges from potential technological advancements that could reduce reliance on live animals for research, although it is currently investing in alternative research methods [10]. Related Transactions - There are ongoing collaborations between Shuyou Shen and Zhaoyan New Drug, with projected service fees of approximately 45.29 million CNY for 2025, reflecting a significant increase from 26.19 million CNY in 2024 [11]. - However, past transactions have raised regulatory concerns due to breaches of commitments regarding related party transactions, leading to administrative measures against Shuyou Shen and its chairman [12].

Group 1 - The core point of the news is that Shuyou Shen's stock price dropped by 5.01% to 33.72 CNY per share, with a trading volume of 269 million CNY and a turnover rate of 1.73%, resulting in a total market capitalization of 16.11 billion CNY [1] - Shuyou Shen (Beijing) Biopharmaceutical Co., Ltd. was established on August 16, 2002, and went public on April 15, 2011. The company primarily engages in the research, production, and sales of biological products and some chemical drugs [1] - The main revenue composition of Shuyou Shen includes: 59.17% from injectable mouse nerve growth factor (Sutai), 33.19% from compound polyethylene glycol electrolyte powder, and 7.63% from other products [1] Group 2 - According to data from the top ten heavy stocks of funds, one fund under GF Fund holds Shuyou Shen as a significant investment. The GF Hong Kong-Shenzhen Medical Mixed A Fund (014114) held 235,700 shares in the second quarter, accounting for 2.86% of the fund's net value, ranking as the tenth largest heavy stock [2] - The GF Hong Kong-Shenzhen Medical Mixed A Fund (014114) was established on December 29, 2021, with a latest scale of 204 million CNY. The fund has achieved an 82% return this year, ranking 223 out of 8171 in its category, and a 95.07% return over the past year, ranking 681 out of 8004 [2] - The fund manager of GF Hong Kong-Shenzhen Medical Mixed A Fund is Wu Xingwu, who has a cumulative tenure of 10 years and 230 days. The total asset scale of the fund is 9.853 billion CNY, with the best fund return during his tenure being 112.46% and the worst being -32.66% [3]

Core Viewpoint - The pharmaceutical sector in the Asia-Pacific market experienced a significant decline, with various indices showing notable drops, particularly in the weight loss drugs, innovative drugs, and CRO sectors [1][2]. Group 1: Market Performance - The A-share pharmaceutical and biotechnology sector saw a downturn, with weight loss drug index dropping by 1.56%, innovative drug index by 0.61%, and CRO index by 0.40% [2]. - Individual stocks such as Sunflower (向日葵) fell over 10%, while Aosaikang (奥赛康) and Guangshengtang (广生堂) also experienced significant declines of 9.02% and 6.56% respectively [3]. Group 2: Hong Kong and Japan Market Impact - The Hang Seng Biotechnology Index opened down nearly 2% and continued to decline, with companies like MicroPort Medical (微创医疗) and BeiGene (百济神州) showing notable drops of 5.47% and 4.75% respectively [4]. - In Japan, companies such as Sumitomo Pharma (住友制药) and Daiichi Sankyo (第一三共) also faced declines exceeding 4% and 3% respectively [4]. Group 3: External Factors - The recent announcement by U.S. President Trump regarding a new round of high tariffs on imported goods, including a punitive 100% tariff on patented and branded pharmaceuticals, is expected to impact the pharmaceutical industry significantly [5].

Group 1 - The A-share market saw a widespread decline in pharmaceutical stocks, with notable drops including Sunflower, Hanyu Pharmaceutical, and Kailaiying, each falling over 3% [1] - The U.S. President announced a new round of high tariffs on various imported products, including a 100% tariff on all brands and patented pharmaceutical products starting October 1 [1] Group 2 - Specific stock performance data shows that ST Complex dropped by 4.98%, with a total market value of 3.886 billion, and a year-to-date decline of 12.94% [2] - Sunflower's market value is 11.1 billion, with a year-to-date increase of 166.98%, despite a recent drop of 3.89% [2] - Hanyu Pharmaceutical's market value stands at 19.8 billion, with a year-to-date increase of 73.62%, and a recent decline of 3.20% [2] - Kailaiying's market value is 39.1 billion, with a year-to-date increase of 44.26%, and a recent drop of 3.01% [2] - Other companies such as Maiwei Bio, Zhaoyan New Drug, and Kanglong Chemical also experienced declines of over 2% [1][2]

Group 1 - The chemical pharmaceutical sector experienced a decline at the beginning of trading on September 26, with Sunflower falling over 10% [1] - Aokang saw a drop of more than 8%, while other companies such as Shutaishen, Hengrui Medicine, Yiming Medicine, and Yuandong Biology also faced declines [1]

证券代码：300204 证券简称：舒泰神 公告编号：2025-070 舒泰神（北京）生物制药股份有限公司 2025 年第二次临时股东会决议公告 本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假 记载、误导性陈述或重大遗漏。 特别提示： 1、本次股东会无增加、变更、否决提案的情况，本次股东会不涉及变更前 次股东会决议。 2、本次股东会以现场投票、网络投票相结合的方式召开。 3、为尊重中小投资者利益，提高中小投资者对公司股东会决议事项的参与 度，本次股东会对中小投资者的表决进行单独计票，中小投资者是指除上市公司 董事、高级管理人员以及单独或者合计持有公司5%以上股份的股东以外的其他 股东。 一、会议召开和出席情况 1、会议通知情况 舒泰神（北京）生物制药股份有限公司（以下简称"公司"）召开 2025 年第 二次临时股东会的通知于 2025 年 09 月 10 日在证监会指定信息披露网站（巨潮 资讯网）公告。 票系统投票的具体时间为：2025 年 09 月 25 日上午 09:15 至下午 15:00 期间的任 意时间。 出席公司 2025 年第二次临时股东会的股东（或委托代理人）492 人，代表 ...

北京市朝阳区建外大街丁 12 号英皇集团中心 8、9、11 层 8/9/11/F, Emperor Group Centre, No.12D, Jianwai Avenue, Chaoyang District, Beijing, 100022, P.R.China 电话/Tel.:010-50867666 传真/Fax:010-56916450 网址/Website:www.kangdalawyers.com 北京 西安 深圳 海口 上海 广州 杭州 沈阳 南京 天津 菏泽 成都 苏州 呼和浩特 香港 武汉 郑州 长沙 厦门 重庆 合肥 宁波 济南 昆明 南昌 北京市康达律师事务所 关于舒泰神（北京）生物制药股份有限公司 2025 年第二次临时股东会的法律意见书 康达股会字【2025】第 0422 号 致：舒泰神（北京）生物制药股份有限公司 根据《中华人民共和国公司法》（以下简称"《公司法》"）、《上市公司 股东会规则》（以下简称"《规则》"）、《深圳证券交易所上市公司股东会网 络投票实施细则》（以下简称"《实施细则》"）、《舒泰神（北京）生物制药 股份有限公司章程》（以下简称"《公司章程》"）及舒泰神（北 ...

本公司及董事会全体成员保证信息披露内容的真实、准确和完整，没有虚假记 载、误导性陈述或重大遗漏。 舒泰神（北京）生物制药股份有限公司（以下简称"公司"）第六届董事会第 九次会议审议通过了《关于提请召开公司2025年第二次临时股东会的议案》，本次 股东会将于2025年09月25日采用现场表决与网络投票相结合的方式召开。《关于召 开2025年第二次临时股东会的通知》已于2025年09月09日刊登于中国证监会指定的 创业板信息披露网站。现将会议有关事项提示如下： 一、召开会议的基本情况 1、股东会届次：2025年第二次临时股东会。 证券代码：300204 证券简称：舒泰神 公告编号：2025-069 舒泰神（北京）生物制药股份有限公司 关于召开 2025 年第二次临时股东会的提示性公告 2、股东会召集人：舒泰神（北京）生物制药股份有限公司董事会。 3、会议召开的合法、合规性：公司第六届董事会第九次会议审议通过了《关于 提请召开公司2025年第二次临时股东会的议案》，决定召开股东会，召集程序符合 有关法律、行政法规、部门规章、规范性文件和公司章程的规定。 4、会议召开日期和时间： （1）现场会议召开时间为：2025年 ...

Core Viewpoint - Shuyou Shen's stock price has shown significant volatility, with a year-to-date increase of 409.18%, but recent declines in the short term raise questions about future performance [1][2]. Company Overview - Shuyou Shen (Beijing) Biopharmaceutical Co., Ltd. was established on August 16, 2002, and listed on April 15, 2011. The company primarily engages in the research, production, and sales of biological products and some chemical drugs [1]. - The main revenue sources are: 59.17% from injectable mouse nerve growth factor (Sutai), 33.19% from compound polyethylene glycol electrolyte powder, and 7.63% from other products [1]. Financial Performance - For the first half of 2025, Shuyou Shen reported revenue of 126 million yuan, a year-on-year decrease of 31.14%, and a net profit attributable to shareholders of -24.64 million yuan, a decline of 619.70% [2]. - The company has distributed a total of 771 million yuan in dividends since its A-share listing, with no dividends paid in the last three years [3]. Shareholder Information - As of June 30, 2025, the number of shareholders increased by 29.20% to 31,700, with an average of 14,327 shares held per shareholder, a decrease of 22.60% [2]. - New institutional shareholders include several funds, with notable holdings such as 15.72 million shares by Xingquan Helun Mixed A and 8.81 million shares by Xingquan Commercial Model Mixed A [3]. Market Activity - On September 18, the stock price rose by 2.00% to 37.73 yuan per share, with a trading volume of 521 million yuan and a turnover rate of 3.09%. The total market capitalization reached 18.026 billion yuan [1]. - The stock has appeared on the daily trading leaderboard seven times this year, with the most recent occurrence on June 9, where it recorded a net buy of -54.65 million yuan [1].

格隆汇9月17日丨舒泰神(300204.SZ)公布，近日，公司收到香塘集团的告知函，香塘集团于2025年09月 10日、2025年09月15日通过证券交易所集中竞价交易方式合计减持141.70万股舒泰神股份，占公司有表 决权总股本的0.30%；2025年09月11日、2025年09月16日通过证券交易所大宗交易方式减持合计477.77 万股舒泰神股份，占公司有表决权总股本的1.00%。2025年09月16日减持完成后，香塘集团及其一致行 动人合计持股比例由2025年09月10日减持前6.99%下降至2025年09月16日减持后的5.69%，减持股份触 及1%整数倍（6%），香塘集团本次减持计划实施完毕。 ...