证券代码：300676 证券简称：华大基因 公告编号：2025-069 深圳华大基因股份有限公司 关于持股 5%以上股东部分股份解除质押及再质押的公告 本公司及董事会全体成员保证信息披露的内容真实、准确、完整，没有虚假记 载、误导性陈述或重大遗漏。 深圳华大基因股份有限公司（以下简称公司或上市公司）近日接到公司持股5% 以上股东深圳生华投资企业（有限合伙）（以下简称生华投资）的通知，获悉生华 投资将其持有的部分公司股份办理了解除质押及再质押。现将具体情况公告如下： 一、股东股份解除质押及再质押的基本情况 （一）本次股东股份解除质押基本情况 截至公告披露日，生华投资所持质押股份情况如下： | | | | | | | | 已质押股份 | | 未质押股份 | | | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | --- | | | | | 本次解除质 | 本次解除质 | 占其所 | 占公司 | 情况 | | 情况 | | | | 持股数量 | 持股比 | 押及再质押 | 押及再质押 | | | 已质押股份 | | | | | 股东名称 | （ ...

Core Insights - The WISE 2025 Business King Conference aims to anchor the future of Chinese business amidst uncertainty, emphasizing the importance of technology and innovative narratives in shaping the business landscape [1] Group 1: Artificial Intelligence and Health - The rapid development of artificial intelligence (AI) is likened to "days feeling like years," with significant implications for various industries, including design and governance [3] - The average life expectancy in Beijing has increased to nearly 84 years, highlighting the importance of long-term thinking in personal and professional pursuits [2] - The potential for technology to extend human life is discussed, with the idea that for every three years lived, technology could add an additional year [3] Group 2: Disease Prevention and Health Management - Major health threats in China include malignant tumors and cardiovascular diseases, which account for approximately 70% of deaths, particularly in rural areas [4] - The five-year survival rate for cancer in China is around 42%-46%, compared to 70% in the US and Japan, indicating a significant gap in healthcare outcomes [4] - Emphasis is placed on preventive measures and lifestyle changes to combat chronic diseases, with a focus on weight control and healthy living [6] Group 3: Aging Population and Future Opportunities - The aging population presents opportunities for new markets, particularly in elder care and health management, with a projected increase in the elderly demographic [8] - Innovations in medical technology, such as organ transplantation from animals, are being explored to address the needs of an aging society [8] - The concept of "longevity" is redefined to encompass not just lifespan but also the quality of life, advocating for a holistic approach to health [11] Group 4: China's Position in Global Health Technology - China is positioned to become a global center for biomedical technology and treatment innovations, supported by recent government initiatives and pilot programs [10] - The accessibility of advanced medical treatments is crucial to prevent disparities in healthcare, ensuring that innovations benefit the broader population [10] - The digitization of health tools is expected to lower costs and improve health outcomes, aligning with national health policies [11]

Core Viewpoint - The event themed "Building a New Engine for the Development of the Biological Economy in Heilongjiang" highlighted the commitment of BGI Group to support the development of Heilongjiang's biological economy through technological innovation and collaboration [2]. Group 1: Company Initiatives - BGI Group aims to establish a comprehensive service system covering precision medicine, public health, and life science research, supported by the establishment of the Heilongjiang BGI Medical Testing Laboratory in 2023 and the Heilongjiang Future Laboratory in 2024 [2]. - The company plans to implement the "Heilongjiang Million Health Cohort" project to collect multi-omics health data from the cold region population, facilitating research and development of new screening and diagnostic technologies for prevalent diseases [3]. Group 2: Strategic Recommendations - BGI Group emphasizes the importance of supporting the "Healthy Heilongjiang" initiative by implementing inclusive projects that reduce medical insurance costs and enhance public health [3]. - The company proposes to develop modern seed industry technologies to ensure the safety of the "Black Soil Granary," focusing on core technologies in seed industry and collaborating with local research institutions to develop proprietary crop varieties [3]. - BGI Group plans to initiate the "Black Soil Microbiome" research project to create new microbial agents and bio-fertilizers aimed at improving soil health and promoting sustainable agricultural development [3].

Core Insights - Qingdao is accelerating marine technology innovation to establish a modern marine economy and aims to transition from a strong research base to a robust industrial base [1] - The city has built the world's largest marine gene bank and leads globally in marine biological gene sequencing capabilities [1] - Qingdao has initiated 84 key technology projects from 2021 to 2024, with a target of achieving 100 breakthroughs by 2027 [1] Group 1: Marine Industry Development - Qingdao is focusing on high-end, intelligent, green, clustered, and integrated development, establishing a "4+4+2" modern marine industry system [1] - The launch of the world's first 150,000-ton smart fishery large-scale breeding vessel "Guoxin 1 Hao 2-1" marks a new phase in the standardization of deep-sea breeding vessel production [1] Group 2: Financial Support and Collaboration - As of Q1 2023, the marine-related loan balance in Qingdao reached 124.086 billion yuan, an increase of 8.09% since the beginning of the year [2] - The city has established a marine technology financial system to support high-quality marine economic development through various financial institutions [2] - Qingdao's marine technology contract transaction volume is expected to exceed 8.7 billion yuan in 2024, reflecting a year-on-year growth of 26% [2] Group 3: Innovation and Collaboration Platforms - Qingdao has created platforms such as the National Marine Technology Transfer Center and the Marine Technology Market to facilitate the transformation of scientific achievements [2] - Since its establishment, the Marine Technology Market has facilitated 121 collaborations between industry, academia, and research [2] - The city held a meeting to plan marine economic development for the next five years, emphasizing the goal of becoming a modern marine center city [2]

该联盟由中国华大集团发起，汇聚了来自中国及东南亚多个国家和地区的知名医疗机构与科研专 家。华大集团董事长、联合创始人汪建在启动仪式上表示，通过防控联盟，将推动区域医疗模式从"被 动治疗"向"主动预防"转变，造福当地民众。 清迈大学副校长比里亚·策沙迪拉恭表示，期待联盟的成立能够加强跨越国界与代际的地贫防控工 作，为改善患者生活质量奠定坚实基础，并为该地区带来新希望。 在联盟启动仪式上，与会各方确立了清晰的战略规划和系统化工作机制，将重点围绕区域合作平 台、能力建设、共享经验、综合防控、公共认知与社会支持五大方向开展工作，致力于显著降低东南亚 地区地贫患儿出生率，提升患者生存质量，减轻患者家庭及社会的经济负担。 新华社曼谷11月25日电 （记者 常天童）东南亚地中海贫血防控联盟24日在泰国清迈成立，旨在联 合东南亚地区各国政府、专家及社区力量，共同加强地中海贫血的防控工作。泰国公共卫生部、清迈大 学、中华骨髓库等机构代表及多位国内外知名基因组学、血液学、遗传学专家出席联盟启动仪式。 地中海贫血（简称"地贫"）作为一种严重的遗传性血液疾病，因血红蛋白合成障碍导致红细胞加速 破坏，严重威胁患者的生命质量和预期寿命。 ...

人民网曼谷11月25日电（记者白元琪）为系统化应对地中海贫血这一重大区域公共卫生挑战，东南亚地中海贫血防控联盟（以下简称"联盟"）于24日在 泰国清迈成立。该联盟由华大集团发起，汇聚了来自中国及东南亚多个国家和地区的顶尖医疗机构与科研专家，标志着东南亚各国在遗传性血液疾病防控领 域迈入了跨国深度合作的新阶段。 地中海贫血是一种严重的遗传性血液疾病，在东南亚地区，其基因携带率和发病率高企，严重威胁着患者的生命质量和预期寿命。联盟秘书长曹苏杰表 示："联盟将通过区域合作，加快人才培训体系以及统一规范的建立，促进防控经验的共享，大幅提升区域整体的地中海贫血防控能力。" 泰国公共卫生部部长帕塔纳·蓬帕特对联盟的启动表示高度肯定，他指出，本次启动会是地中海贫血高发的东南亚国家分享知识、交流解决方案、学习 最佳实践的一次重要机遇。泰国正将先进疗法药物产品和精准医疗作为核心政策，全面强化和推进医疗卫生系统。 泰国公共卫生部部长帕塔纳·蓬帕特致辞。主办方供图 清迈大学副校长皮里亚·切萨迪拉古指出，联盟通过区域合作，加强跨越国界与代际的地中海贫血防控工作，为改善患者生活质量奠定坚实基础，并为 该地区带来新的希望。 华大集团董事 ...

Group 1 - The 2025 International Youth Innovation Conference (YSS) was successfully held in Shenzhen, focusing on the theme "Intelligent Creation Without Boundaries, Integration and Coexistence," aiming to create a global cooperation platform for technology, capital, and ecology [2] - The conference featured prominent figures including former UN Deputy Secretary-General Fabrizio Hochschild and leaders from various sectors, establishing an international tone for the event [2] - The conference included various formats such as keynote forums, sub-forums, technology exhibitions, and cross-border activities to inject new momentum into the global innovation ecosystem [2] Group 2 - The Robotics Forum titled "Form and Intelligence: New Dialogue" gathered industry leaders and experts to discuss the future development paths of robotics under the integration of form and intelligence [3] - Wang Peng, a partner at Waterwood Capital, emphasized the importance of international cooperation in data governance and the industrialization of robotics during his speech [3][5] - Wang analyzed the current state and challenges of AI global data governance and introduced the feasibility of Sino-European robot training factory cooperation, highlighting the complementary nature of European precision technology and Chinese large-scale data [5] Group 3 - Shenzhen's robot industry has a production value exceeding 200 billion, with 74,000 enterprises and significant technological breakthroughs, providing a solid foundation for cooperation [5] - Wang Peng joined the YSS expert think tank to contribute to the development of a healthy and robust science and technology investment ecosystem [5] - The Fourth Davos Global Fund of Funds Summit is scheduled to take place in January 2026, marking a significant multilateral dialogue in the global fund of funds industry [6][8]

公开资料显示，李宁为1981年出生的80后，中国国籍且无境外居留权，拥有博士学历。他在华大基因任 职经历丰富，曾任国际区域规划发展中心负责人、国际事业部负责人、首席发展官，以及深圳华大基因 科技有限公司欧非片区总经理、深圳华大基因研究院项目总监等职，辞职前还担任公司科技服务事业部 负责人。 近日，深圳华大基因股份有限公司（以下简称"华大基因"）发布公告称，董事、副总经理李宁因工作安 排原因申请辞去副总经理职务，其辞任申请自董事会收到辞任报告之日起生效。公告显示，李宁辞任后 将继续担任华大基因董事，并在控股子公司担任相关职务，其原定高级管理人员任期为2024年6月18日 至2027年6月17日。 薪酬方面，据华大基因2024年年报数据，李宁2024年税前报酬总额为140.74万元，较2023年的107.2万元 增长31.25%，增幅达33.58万元。在剔除独立董事、监事会主席及监事后的15位董事和高级管理人员 中，该薪酬位列第三，仅次于总经理赵立见的213.8万元和副总经理朱师达的150.23万元。从年龄维度 看，44岁的李宁在这15人中年序排名第10，低于48岁的平均年龄和46岁的年龄中位数。 股权持有情况显 ...

Core Insights - The medical services sector experienced a decline of 0.76% on November 18, with Baihua Pharmaceutical leading the drop [1] - The Shanghai Composite Index closed at 3939.81, down 0.81%, while the Shenzhen Component Index closed at 13080.49, down 0.92% [1] Medical Services Sector Performance - Chengda Pharmaceutical saw a significant increase of 20.01%, closing at 59.50, with a trading volume of 250,400 shares and a transaction value of 1.45 billion [1] - Other notable gainers included Digital Human (+4.49%), Dian Diagnostics (+3.84%), and Meinian Health (+3.25%) [1] - Conversely, Zihua Pharmaceutical led the declines with a drop of 4.39%, closing at 10.23, followed by Innovative Medical (-3.86%) and Tigermed (-3.42%) [2] Capital Flow Analysis - The medical services sector experienced a net outflow of 1.348 billion from institutional investors, while retail investors saw a net inflow of 1.001 billion [2][3] - Notable stocks with significant capital inflows included Meinian Health with a net inflow of 1.39 billion, while Chengda Pharmaceutical had a net inflow of 931.01 million [3] - The overall trend indicates a shift in investor sentiment, with retail investors actively participating despite institutional outflows [2][3]

Core Viewpoint - The resignation of Mr. Li Ning as Vice President of Shenzhen BGI Genomics Co., Ltd. is due to work arrangement reasons, but he will continue to serve as a director of the company and hold positions in its subsidiaries [2][3]. Summary by Sections Resignation Details - Mr. Li Ning's resignation as Vice President is effective immediately upon the board's receipt of his resignation report, and he will maintain his role as a director [2][3]. - His original term as a senior executive was from June 18, 2024, to June 17, 2027 [3]. Shareholding Information - As of the announcement date, Mr. Li holds 122,600 shares directly and has 1,037,880 shares through the company's second employee stock ownership plan [3]. - His associates do not hold any shares in the company [3]. Compliance and Transition - Mr. Li has completed the necessary work handover in accordance with the company's regulations, ensuring that his resignation will not affect the company's daily operations and management [4]. - The board expressed gratitude for Mr. Li's contributions during his tenure [4].