康方生物:AK112 to validate its potential as next-generation IO therapy-20250402
Zhao Yin Guo Ji· 2025-04-02 01:23
Investment Rating - The report maintains a "BUY" rating for Akeso, indicating a potential return of over 15% over the next 12 months [15]. Core Insights - Akeso's FY24 results showed strong cost controls despite a revenue shortfall, with total revenue of RMB2.1 billion, including RMB2.0 billion from product sales, representing a 25% YoY increase [8]. - The company is expected to see product sales surge by 60% YoY to RMB3.3 billion in FY25, driven by the inclusion of AK104 and AK112 in the National Reimbursement Drug List (NRDL) [8]. - AK112 is positioned as a next-generation immuno-oncology (IO) therapy, with pivotal clinical data demonstrating a meaningful progression-free survival (PFS) benefit in a Phase 3 trial against Keytruda for first-line PD-L1-positive non-small cell lung cancer (NSCLC) [8]. - The report highlights ongoing clinical trials for AK112 in various cancer types, including triple-negative breast cancer (TNBC) and pancreatic cancer, indicating a broad first-line strategy [8]. - The target price for Akeso has been raised from HK$58.97 to HK$102.61, reflecting increased sales projections for AK112 [8]. Financial Summary - For FY23A, Akeso reported revenue of RMB4,526 million, with a YoY growth of 440.3%, followed by a projected revenue of RMB2,124 million for FY24A, reflecting a decline of 53.1% [2]. - The net profit for FY23A was RMB2,028.3 million, with a projected net loss of RMB501 million for FY24A [2]. - R&D expenses are projected to be RMB1,306 million for FY25E, increasing to RMB1,937 million by FY27E [2]. - The company held a cash balance of RMB7.3 billion at the end of FY24, sufficient to support ongoing R&D and future commercial expansion [8]. Share Performance - Akeso's current market capitalization is HK$77,191.5 million, with a current price of HK$86.00 and a target price indicating a 19.3% upside [3]. - The stock has shown strong performance, with a 1-month absolute return of 17.9% and a 3-month return of 41.7% [5]. Valuation - The DCF valuation estimates the equity value at RMB 85,652 million, translating to a DCF per share of RMB 95.43 or HK$ 102.61 [9]. - The report includes a sensitivity analysis indicating how changes in the weighted average cost of capital (WACC) and terminal growth rate affect the target price [10].
固生堂(02273):024年业绩维持高增速,AI赋能有望拓展全新增长空间
Guoxin Securities· 2025-04-02 01:13
证券研究报告 | 2025年04月02日 固生堂(02273.HK) 优于大市 2024 年业绩维持高增速,AI 赋能有望拓展全新增长空间 2024 年公司收入维持高增速,AI 赋能有望带来业务能力提升。2024 年公司 实现营收 30.22 亿元(+30.1%),溢利净额 3.07 亿元(+21.6%),经调整 溢利净额 4.00 亿元(+31.4%)。2024 年公司旗下医疗机构延续 2023 年高 速增长的态势,彰显了公司业务的发展韧性;公司保持外延迅速扩张的节奏, 拓展国内的覆盖范围及市场份额,同时于上半年进军新加坡市场,迈出国际 化第一步。凭借内生增长和外延并购的双轮驱动,以及线下医疗机构和线上 健康平台相结合的业务模式,公司民营中医连锁服务机构龙头地位日渐稳 固。此外,叠加公司将推出的名医"AI 分身"为公司的诊疗质量和水平带来 的提升,公司未来增长势头依然强劲。 客户群持续增长,诊疗量与会员人数同比提升。按营收拆分来看,医疗健康 解决方案 2024 年实现收入 29.88 亿元(+30.6%),占总收入的 98.9%。2024 年全年,公司新增客户 88.9 万人,总就诊人次达到 541.1 万 ...
固生堂(02273):AI赋能中医服务龙头
Zhao Yin Guo Ji· 2025-04-02 01:02
2025 年 4 月 2 日 招银国际环球市场 | 睿智投资 | 公司更新 固生堂 (2273 HK) AI 赋能中医服务龙头 资料来源:公司资料、彭博及招银国际环球市场预测 | 目标价 | 52.38 港元 | | --- | --- | | (此前目标价 | 56.50 港元) | | 潜在升幅 | 57.5% | | 当前股价 | 33.25 港元 | 中国医药 武 煜, CFA (852) 3900 0842 jillwu@cmbi.com.hk 黄本晨, CFA huangbenchen@cmbi.com.hk 公司数据 固生堂发布 24 年度业绩,收入同比增长 30.1%至 30.2 亿元,经调整净利润同比 增长 31.4%至 4.0 亿元。公司的收入符合我们的预期,但利润端比我们的预测高 3.1%。公司业绩在医保监管趋严的情况下保持了高速的增长,体现出固生堂作为 龙头企业的合规性以及强劲发展势头。受益于强劲增长的客户需求,公司线下收 入同比增长 35%,其中老店收入同比增长 28%,门诊人次同比增长 25.9%,客单 价同比增长 3.3%。公司持续推进医联体合作,全年新增 8 家医联体合作单位。 ...
老铺黄金:2024年营收业绩强劲增长,2025年推动品牌出海-20250402
Shanxi Securities· 2025-04-02 00:23
来源:最闻,山西证券研究所 | 市场数据:2025 年 3 月 | 31 | 日 | | | --- | --- | --- | --- | | 收盘价(港元): | | | 729.00 | | 年内最高/最低(港元): | | | 798.00/60.950 | | 流通股/总股本(亿股): | | | 0.95/1.68 | | 流通市值(亿港元): | | | 690.91 | | 总市值(亿港元): | | | 1,227.39 | 来源:最闻,山西证券研究所 黄金珠宝 老铺黄金(06181.HK) 增持-A(维持) 分析师: 王冯 执业登记编码:S0760522030003 邮箱:wangfeng@sxzq.com 孙萌 执业登记编码:S0760523050001 邮箱:sunmeng@sxzq.com 2024 年营收业绩强劲增长,2025 年推动品牌出海 2025 年 4 月 1 日 公司研究/公司快报 事件描述 3 月 31 日,公司披露 2024 年年报,2024 年,公司实现收入 85.06 亿元,同比增长 167.5%,实现归母净利润 14.73 亿元,同比增长 253.9%。公司董事 ...
三生制药(01530):2024年核心品种稳健增长,新药出海有望提供弹性
Hua Yuan Zheng Quan· 2025-04-01 23:46
Investment Rating - The investment rating for the company is "Buy" (maintained) [5] Core Views - The company is expected to achieve steady growth in core products in 2024, with new drugs potentially providing flexibility in revenue generation [5][7] - The company reported a total revenue of 9.108 billion RMB in 2024, representing a year-on-year growth of 16.5%, with drug sales contributing 8.928 billion RMB, also up by 16.8% [7] - The net profit attributable to shareholders reached 2.09 billion RMB, marking a significant increase of 34.9% year-on-year [7] - Key products such as Tevizo and Mandi are experiencing robust growth, with Tevizo sales projected at 5.06 billion RMB in 2024, reflecting a 20.4% increase [7] - The company has a promising pipeline of innovative drugs, including the PD1/VEGF dual antibody, which shows potential for high returns from overseas markets [7] Financial Summary - Revenue projections for the company are as follows: 10.102 billion RMB in 2025, 11.164 billion RMB in 2026, and 12.430 billion RMB in 2027, with growth rates of 10.9%, 10.5%, and 11.3% respectively [6][8] - The net profit attributable to shareholders is forecasted to be 2.343 billion RMB in 2025, with a growth rate of 12.1% [6][8] - The company's price-to-earnings ratio (P/E) is projected to be 12.42 in 2025, decreasing to 9.68 by 2027 [6][8] - The company aims for a target market value of 40 billion RMB, supported by steady growth in core business and innovative products [7]
赢家时尚(03709):逆境之下规模稳定,线上渠道表现亮眼
Shenwan Hongyuan Securities· 2025-04-01 15:21
Investment Rating - The report maintains an "Outperform" rating for the company [2] Core Insights - The company reported a revenue of 6.589 billion RMB for FY2024, a decrease of 4.7% year-on-year, and a net profit of 469 million RMB, down 43.1% year-on-year, which aligns with expectations [7] - The company aims to build a Chinese luxury brand management group and has shown strong multi-brand operational capabilities, with potential for stronger growth momentum under new positioning and management upgrades [7] - The online sales channel has shown significant growth, with a 17% increase in revenue to 1.13 billion RMB in FY2024, contributing to the overall performance despite challenges in the retail environment [7] Financial Data and Profit Forecast - Revenue and profit forecasts for the company are as follows: - FY2023: Revenue 6,912 million RMB, Net Profit 838 million RMB - FY2024: Revenue 6,589 million RMB, Net Profit 469 million RMB - FY2025E: Revenue 6,998 million RMB, Net Profit 642 million RMB - FY2026E: Revenue 7,402 million RMB, Net Profit 707 million RMB - FY2027E: Revenue 7,775 million RMB, Net Profit 772 million RMB - The company’s net profit is expected to recover to 6.4 billion RMB by FY2025, with corresponding PE ratios of 8, 7, and 6 for FY2025E, FY2026E, and FY2027E respectively [6][17] Brand Performance - The revenue performance of the company's eight brands shows a mixed trend, with three brands increasing and five decreasing: - Koradior: 2.16 billion RMB, down 9.7% - NAERSI: 1.44 billion RMB, down 2% - NEXY.CO: 1.01 billion RMB, up 1% - La Koradior: 510 million RMB, up 10% - FF: 170 million RMB, up 22% [7][14] Store Optimization and E-commerce Growth - The total number of stores decreased by 125 to 1,839, with a focus on optimizing store quality and enhancing sales performance [7] - The company has successfully expanded its e-commerce channels, with significant contributions from platforms like Vipshop and Douyin, indicating a strategic shift towards online sales [15]
越秀地产(00123):港股公司点评:短期业绩承压,25年销售目标上升
SINOLINK SECURITIES· 2025-04-01 15:20
Investment Rating - The report maintains a "Buy" rating for the company, expecting a price increase of over 15% in the next 6-12 months [4]. Core Insights - The company reported a revenue of 86.4 billion yuan for 2024, a year-on-year increase of 7.7%, but the net profit attributable to shareholders fell to 1.04 billion yuan, a decline of 67.3% [1][4]. - The decline in net profit is primarily attributed to the downturn in the real estate market, with a gross margin of 10.5% for 2024, down 4.8 percentage points year-on-year [2]. - The company demonstrated stronger sales performance compared to peers, with a contract sales amount of 114.5 billion yuan in 2024, a decrease of 19.4%, while the top 10 real estate companies saw a decline of 24.4% [2]. - The company has set a sales target of 120.5 billion yuan for 2025, representing a 5.2% increase compared to the 2024 sales completion [2]. Financial Performance - The company maintains a healthy financial position, with key financial metrics remaining in the green zone as of the end of 2024. The asset-liability ratio, net debt ratio, and cash-to-short-term debt ratio are 68.1%, 51.7%, and 2.1 times, respectively [3]. - The total borrowings amount to 103.9 billion yuan, a slight decrease of 0.5% year-on-year, with short-term debt accounting for 22% of total borrowings [3]. - The weighted average borrowing cost has decreased to 3.49%, down by 0.33 percentage points year-on-year [3]. Future Projections - The company is expected to experience a bottoming phase in settlement performance for 2024-2025, with potential recovery in profit performance as high-margin projects are recognized and impairment pressures ease [4]. - Projected net profits for 2025-2027 are estimated at 1.02 billion yuan, 1.24 billion yuan, and 1.36 billion yuan, with year-on-year growth rates of -1.9%, +21.4%, and +10.1%, respectively [4].
毛戈平(01318):港股公司信息更新报告:2024年收入利润增长超30%,高端品牌势能持续向上
KAIYUAN SECURITIES· 2025-04-01 15:06
Investment Rating - The investment rating for the company is "Buy" (maintained) [1] Core Insights - The company reported a revenue growth of over 30% in 2024, with total revenue reaching 3.885 billion yuan (up 34.6% year-on-year) and a net profit of 881 million yuan (up 33.0% year-on-year) [4][5] - The company is expected to continue its strong performance, with projected net profits for 2025-2027 at 1.179 billion, 1.536 billion, and 1.939 billion yuan respectively, reflecting a compound annual growth rate of approximately 33.9% [4][7] - The company's gross margin for 2024 was 84.4%, with a stable expense ratio across sales, management, and R&D [5][7] Financial Summary and Valuation Metrics - Revenue and net profit projections for 2025 are 5.184 billion yuan and 1.179 billion yuan respectively, with an expected EPS of 2.41 yuan [7] - The company's P/E ratios for 2025, 2026, and 2027 are projected to be 41.9, 32.2, and 25.5 respectively, indicating a favorable valuation trend [7] - The company maintains a high return on equity (ROE) of 32.7% for 2025, reflecting strong profitability [7]
绿城中国(03900)港股公司信息更新报告:减值影响净利表现,周转提速,坚决布局核心城市
KAIYUAN SECURITIES· 2025-04-01 15:05
房地产/房地产开发 绿城中国(03900.HK) 2025 年 04 月 01 日 投资评级:买入(维持) | 日期 | 2025/4/1 | | --- | --- | | 当前股价(港元) | 11.340 | | 一年最高最低(港元) | 13.780/0.000 | | 总市值(亿港元) | 287.39 | | 流通市值(亿港元) | 287.39 | | 总股本(亿股) | 25.34 | | 流通港股(亿股) | 25.34 | | 近 3 个月换手率(%) | 38.95 | 股价走势图 数据来源:聚源 -40% 0% 40% 80% 120% 160% 2024-04 2024-08 2024-12 绿城中国 恒生指数 相关研究报告 《减值影响业绩表现,拿地强度维持 高 位 — 港 股 公 司 信 息 更 新 报 告 》 -2025.2.11 《销售拿地表现亮眼,行业排名持续 攀 升 — 港 股 公 司 信 息 更 新 报 告 》 -2025.1.10 《公开市场拿地稳健积极,销售均价 显著提升—港股公司信息更新报告》 -2024.12.9 减值影响净利表现,周转提速,坚决布局核心城市 —— ...
老铺黄金(06181):2024年业绩点评:全年业绩同比+254%,品牌破圈推动同店高增
Soochow Securities· 2025-04-01 14:34
Investment Rating - The investment rating for the company is "Buy" (maintained) [1] Core Views - The company achieved a revenue of 8.506 billion yuan in 2024, representing a year-on-year increase of 167.5%, and a net profit of 1.473 billion yuan, up 253.9% year-on-year. The strong performance is attributed to the brand's rapid expansion and high same-store sales growth [7] - The company plans to distribute a dividend of 6.35 yuan per share, totaling approximately 1.07 billion yuan, with a payout ratio of 72.6% [7] - The company's gross margin for 2024 was 41.2%, with a net profit margin of 17.3%, benefiting from improved cost control and economies of scale [7] - The company is experiencing a dual-channel growth with significant increases in both offline and online sales, with offline revenue reaching 7.45 billion yuan (up 164.3%) and online sales at 1.26 billion yuan (up 192%) [7] - The company is positioned as a leading brand in the ancient gold category in China, with a strong reputation among high-net-worth clients, and is expected to continue its growth trajectory with international expansion [7] Financial Summary - For 2024, the total revenue is projected at 8.506 billion yuan, with a net profit of 1.473 billion yuan, and an EPS of 8.75 yuan [1][8] - The company’s net profit forecasts for 2025-2027 have been revised upwards to 3.556 billion yuan, 5.644 billion yuan, and 7.232 billion yuan respectively, with corresponding P/E ratios of 32, 20, and 16 [7] - The company’s total assets are projected to reach 6.337 billion yuan by 2024, with a debt ratio of 24.57% [6][8]