不仅仅是创新药，低迷数年的院外医药赛道也正重新成为公募基金卡位时代的新机会。 券商中国记者注意到，随着关税因素促使内需消费成为公募基金二季度挖掘股票的核心考量，叠加院外医药市 场复苏，今年四月底开始，易方达、广发、华夏、平安基金等多家头部公募基金频频调研各大连锁药店上市公 司，甚至有非医药的A股基金经理将十大重仓股席位几乎一半都安排在连锁药店赛道上，凸显出闭店潮强弩之 末时，基金经理已嗅到行业见底反转的机遇。 与A股基金经理策略相互呼应的是，虽然日本也在经历药店闭店潮，但今年一季度开始有全球著名的基金产品 在日本市场重仓四只连锁药店股票并大幅度获利，多个重仓中国连锁药店的A股基金经理则解释核心逻辑是挖 掘该赛道行业反转的可能性，并关注该赛道在经营场景中逐步增加慢病管理、宠物经济、保健品、药妆甚至彩 票等多元化业务带来的天花板突破机会。 闭店潮强弩之末，公募重新审视连锁药店赛道 在经历连续两年的闭店潮后，公募基金眼中的院外医药行业正迎来底部的战略性机会。 "连锁药店未来十年的需求是十分强劲的，消费支出场景可能不仅仅是用户进店买药，过去两年的关店潮会促 使市场集中度进一步提升，从而强化和增厚行业龙头的份额占有率和 ...

Investment Rating - The industry investment rating is "stronger than the market" indicating an expected performance that exceeds the market by more than 5% over the next six months [49]. Core Views - The chemical agents and blood products sectors are expected to perform outstandingly in 2024, with positive revenue and profit growth reported in the CXO and medical services (hospitals) sectors for Q1 2025 [4][5]. - The biopharmaceutical industry is anticipated to outperform the market overall [4]. Summary by Sections Industry Performance - As of April 30, 2025, 467 A-share biopharmaceutical companies reported their 2024 annual and Q1 2025 results. In 2024, 28 companies had revenue growth exceeding 30%, while 50 companies exceeded 20%, and 113 companies exceeded 10%. Approximately 220 companies reported positive revenue growth, while 246 experienced negative growth. On the profit side, 102 companies had profit growth over 30%, 132 over 20%, and 172 over 10%, with 218 maintaining positive profit growth and 249 facing negative growth [4]. - In Q1 2025, 24 companies reported revenue growth over 30%, 52 over 20%, and 109 over 10%, with 214 maintaining positive revenue growth and 251 reporting negative growth. For profits, 100 companies had growth over 30%, 120 over 20%, and 159 over 10%, with 220 maintaining positive profit growth and 240 facing negative growth [4]. Investment Strategies - Focus on "innovation," "going global," "equipment upgrades," and "consumption recovery." - **Innovation**: Invest in globally competitive innovative drugs and categories with significant market potential. Recommended companies include BeiGene, Dongcheng Pharmaceutical, and others [7]. - **Going Global**: Explore overseas markets for long-term opportunities, with companies like Mindray Medical and others highlighted [7]. - **Equipment Upgrades**: Expect support for medical equipment updates from central and local government financing, with companies like Mindray Medical and others recommended [7]. - **Consumption Recovery**: Anticipate recovery in quality sectors like ophthalmology and medical aesthetics, with companies such as Puri Eye Hospital and others suggested [7]. Key Companies to Watch - **Nocare Biopharma**: Expected to achieve over 1 billion yuan in revenue from its core product, with a 49% year-on-year sales increase. The company reported a gross margin of 86.3% and a significant reduction in losses [8]. - **Sihuan Pharmaceutical**: Strong fundamentals with core products maintaining growth, and a robust pipeline expected to yield multiple approvals from 2025 to 2027 [11]. - **China Biopharmaceutical**: Rapid revenue growth with an increasing share of innovative products, and a strong pipeline in oncology [13]. - **Aibo Medical**: Anticipated growth in high-end artificial lenses and recovery in consumption due to aging trends [23]. Industry News Highlights - BeiGene's Sonrotoclax NDA application has been accepted for review, indicating potential market entry for a new treatment for CLL/SLL [30]. - Novartis' Pluvicto has received acceptance for a new indication in China, expanding its market potential [31]. - The partnership between Fuhong Hanlin and Sandoz for HLX13 indicates a significant milestone in the commercialization of biosimilars [33].

Investment Rating - The report indicates a cautious outlook for the pharmaceutical industry, with a focus on recovery in 2024 after a challenging 2023 due to anti-corruption measures [6][19]. Core Insights - The pharmaceutical industry is projected to see a decline in sales revenue and net profit for 2024 compared to 2023, with total sales revenue growth at -0.46%, net profit at -6.73%, and non-recurring net profit at -11.97% [2][13]. - The fastest-growing segments in Q4 2024 are expected to be CXO, medical devices, and pharmaceutical distribution, while in Q1 2025, the growth leaders will shift to CXO, pharmacies, and pharmaceutical distribution [22]. - The report highlights a significant slowdown in growth for traditional Chinese medicine and a mixed performance across various sectors, with some showing resilience and others facing challenges [5][24]. Summary by Sector Pharmaceutical Industry - In 2024, the total revenue growth for 405 pharmaceutical companies is projected at -0.46%, with net profit declining by 6.73% [2][13]. - Q1 2025 shows a continued decline in revenue and net profit, indicating ongoing challenges [13]. Traditional Chinese Medicine - For 62 listed companies in traditional Chinese medicine, revenue and net profit are expected to decline by -3.9% and -14.6% respectively in 2024, with further declines in Q1 2025 [24][32]. Chemical Preparations - The 96 chemical preparation companies are expected to see revenue growth of 1.2% and net profit growth of 15.7% in 2024, with a slight slowdown in Q1 2025 [2][5]. Research Services - The 16 research service companies are projected to experience a revenue increase of 6.56% in 2024, despite a significant drop in net profit [2][5]. Medical Services - The 11 medical service companies are expected to face revenue growth of 1.4% in 2024, with a notable recovery in Q1 2025 [2][5]. Medical Devices - The 97 medical device companies are projected to see a slight revenue increase of 1.16% in 2024, with a decline in net profit [2][5]. Biopharmaceuticals - The 54 biopharmaceutical companies are expected to see a revenue decline of -6.9% in 2024, with a significant drop in Q1 2025 [3][5]. CXO - The 22 CXO companies are projected to experience a revenue decline of -4.14% in 2024, but a recovery is anticipated in Q1 2025 with a revenue increase of 13.1% [3][5]. Raw Materials - The 50 raw material companies are expected to see a slight revenue increase of 2.48% in 2024, with a recovery trend starting in Q1 2025 [3][5]. Pharmacies - The 7 pharmacy companies are projected to see revenue growth of 4.9% in 2024, but face challenges in Q1 2025 [2][5]. Pharmaceutical Distribution - The 22 pharmaceutical distribution companies are expected to see a slight revenue increase of 0.27% in 2024, with ongoing challenges in Q1 2025 [2][5].

Core Points - The current season marks the implementation of dividend distribution for listed companies, with 31 companies executing their distribution plans today [1] - A total of 3,529 companies have announced distribution plans for the 2024 fiscal year, with 3,525 of them including cash dividends, amounting to a total cash payout of 1.56 trillion yuan [1] - The implementation of cash dividends is increasingly active among listed companies, reflecting regulatory encouragement for cash dividends [1] Dividend Distribution Details - Among the companies with distribution plans, 26 companies are offering cash dividends of 1 yuan (after tax) or more per 10 shares, with Aimeike leading at 38.00 yuan per 10 shares [1] - The companies with the highest stock transfer ratios include Zhucheng Technology, Tongye Technology, and Leirwei, each offering a transfer of 4 shares for every 10 shares held [2] - The stock performance of companies with distribution plans shows that Sanwei Chemical has the highest increase over the past five days, with a rise of 23.38% [2] Company Performance Overview - A summary of companies with upcoming dividend distributions includes: - Sanwei Chemical: 3.00 yuan per 10 shares, latest closing price 9.87 yuan, 5-day increase 23.38% [2] - Yunnan Baiyao: 11.85 yuan per 10 shares, latest closing price 57.91 yuan, 5-day increase 1.22% [2] - Aimeike: 38.00 yuan per 10 shares, latest closing price 173.53 yuan, 5-day decrease -2.68% [3]

Investment Highlights - The agricultural sector is recognized as a fundamental industry with significant resilience, characterized by domestic supply shortages, historical price declines, and low asset prices, leading to increased investment value in the sector [10][12] - The current phase of agricultural stock price increases is believed to be in the early stage of the second phase, transitioning from emotional stimulation to industrial logic development [10] - The report highlights the importance of maintaining grain security and farmer income resilience, with a target grain production of 1.4 trillion jin for 2025 [10] Agriculture Sector - The pig price is expected to remain stable in the short term, with recent data showing a price of 14.78 yuan/kg and a slight increase in breeding stock [11][12] - The chicken market is experiencing a rebound, with prices for live chickens and chicks showing signs of recovery, indicating a shift in the industry towards upstream breeding sources [13] - The feed sector is recommended to focus on companies like Hai Da Group, which is expected to benefit from improved cash flow and overseas growth [14][15] Energy Sector - Wind and solar power installations have surpassed thermal power for the first time, with a total installed capacity of 1.482 billion kW for wind and solar combined [24][25] - The report emphasizes the acceleration of offshore wind projects and the potential for domestic cable manufacturers to benefit from European market demand [27][29] - The introduction of new policies is expected to enhance the market entry of renewable energy sources, with significant growth anticipated in the offshore wind sector [26][30] Pharmaceutical Sector - The demand for new drugs for depression and epilepsy is highlighted, with a focus on companies like Warner Pharmaceuticals and Hainan Haiyao, which are developing innovative treatments [32][35] - The report notes the significant unmet need in the epilepsy market, with an estimated market size exceeding 50 billion yuan in China [35] - Warner Pharmaceuticals' ZG001, a derivative of ketamine, is in clinical trials and has the potential to revolutionize depression treatment [36] Consumer Sector - The pet food market is experiencing steady growth, with a compound annual growth rate of approximately 10% from 2020 to 2024, particularly in the cat food segment [4][21] - The report indicates that exports of pet food have increased significantly, with a total export volume of 30,000 tons in March, reflecting a 24.6% year-on-year growth [17][20] - Companies like Lu Si Co. are identified as key players in the pet food industry, focusing on quality control and product development [4][21] Construction Materials Sector - The report emphasizes the importance of domestic demand and cyclical investment opportunities in the construction materials sector, particularly in light of recent political meetings that prioritize internal circulation [5][6] - Companies like San Ke Shu are noted for their competitive advantages in the paint sector, with expectations for improved performance as the market stabilizes [8][9] Transportation Sector - The logistics company Debang is experiencing short-term pressure on earnings but is expected to improve profitability through operational enhancements [8][9] - The report highlights the company's revenue growth driven by strategic adjustments and network integration [8][9]

Investment Rating - The industry investment rating is "stronger than the market" [3][47]. Core Viewpoints - The approval of Ivosidenib for first-line treatment of NSCLC in China is a significant milestone, being the first to show positive results in a clinical trial comparing it to Pembrolizumab [3]. - The HARMONi-2 trial demonstrated that Ivosidenib significantly improved progression-free survival (mPFS of 11.14 months vs. 5.82 months for Pembrolizumab), with a hazard ratio (HR) of 0.51, indicating a 49% reduction in the risk of disease progression or death [3]. - The interim analysis of overall survival (OS) at 39% maturity showed a 22.3% reduction in mortality risk for Ivosidenib compared to Pembrolizumab (HR=0.777) [3]. Summary by Sections Industry News - Ivosidenib has received approval for a new indication in first-line treatment of PD-L1 positive locally advanced or metastatic NSCLC based on the HARMONi-2 trial results [3]. - The trial involved a randomized comparison of Ivosidenib and Pembrolizumab, with primary endpoints focused on progression-free survival (PFS) [3]. - Additional studies have shown Ivosidenib's efficacy in various NSCLC settings, including in combination with chemotherapy [4]. Investment Strategy - The report suggests focusing on "innovation," "overseas expansion," "equipment upgrades," and "consumption recovery" as key investment themes [6]. - Companies to watch include innovative drug developers and those with strong overseas market potential, such as BeiGene, Dongcheng Pharmaceutical, and others [6]. Key Companies to Watch - **Nocera Healthcare**: Expected to achieve over 1 billion yuan in revenue from its core product, with a 49% year-on-year growth in sales [7]. - **Sihuan Pharmaceutical**: Strong fundamentals with a stable growth outlook, particularly in the ADC market [10]. - **China Biopharmaceutical**: Rapid revenue growth with a focus on innovative products, particularly in oncology [11]. - **Aier Eye Hospital**: Benefiting from increasing demand for eye care services and a strong pipeline of new products [20].

Core Insights - The Chinese medicine clinic industry is experiencing explosive growth, with the number of private clinics reaching 86,317 in 2023, a year-on-year increase of 16% [1][8] - The industry is supported by favorable government policies aimed at expanding the number of clinics and improving healthcare services [4][20] - The market is expected to continue expanding, with projections indicating that the number of private clinics could reach around 90,000 by 2024 [1][8] Industry Overview - Chinese medicine clinics provide healthcare services based on traditional Chinese medicine theories, utilizing both herbal and non-drug therapies [1] - The clinics serve as a platform for the promotion of Chinese culture and are part of the national strategy for developing grassroots healthcare [1] Industry Environment - Recent government policies have shifted from encouraging pilot programs to establishing mandatory targets, driving the expansion of Chinese medicine clinics [4] - The demand for healthcare services is increasing due to an aging population, urbanization, and rising health awareness [1][4] Industry Status - The number of private Chinese medicine clinics has seen a significant increase, with a 4.2-fold growth in the rate of new openings compared to 2022 [1][8] - The average spending per visit at Chinese medicine clinics has also risen, indicating a shift towards higher-quality services [10] Competitive Landscape - Capital investment in the Chinese medicine clinic sector is increasing, with successful public listings of companies attracting more attention [12] - Major players in the industry include Guoshengtang, Tongrentang, and Yuenanqing, which are expanding their clinic networks into second and third-tier cities [12][15] Future Trends - The market size of the Chinese medicine clinic industry is expected to continue expanding, driven by an increase in service quality and a shift towards self-paid services [17] - Digital transformation and the adoption of technologies such as AI and big data are anticipated to enhance service efficiency and patient experience [18] - Government support for the industry is expected to facilitate the integration of the supply chain and promote international expansion [20]

Core Viewpoint - The recent announcement by the National Medical Products Administration and the General Administration of Customs to allow the import of cow bile for traditional Chinese medicine production is expected to alleviate the supply shortage and stabilize prices of cow bile, benefiting high-end traditional Chinese medicine companies like Tong Ren Tang and Pian Zai Huang [2][3][12]. Group 1: Policy Changes and Implications - The pilot program for importing cow bile will last for two years and is limited to specific regions in China, allowing only designated companies to use the imported cow bile for their own production [5][7]. - The import of cow bile is a significant policy shift after nearly 24 years of restrictions due to concerns over mad cow disease, which had previously led to a complete ban on imported bovine materials [5][6]. - The pilot aims to create a controlled supply chain, ensuring that imported cow bile is used solely within the group of companies that import it, preventing external sales [7][8]. Group 2: Market Dynamics and Supply Chain - The natural cow bile market in China faces a significant supply-demand gap, with an annual demand of approximately 5 to 8 tons against a domestic production of only about 900 kilograms [6][12]. - The global cattle population is approximately ten times that of China, indicating a substantial potential for international supply to meet domestic needs [6]. - The introduction of imported cow bile is expected to lead to a stratified supply chain, where larger companies can better manage resources and mitigate price fluctuations in the international market [7][8]. Group 3: Price Trends and Market Reactions - The price of natural cow bile has seen a dramatic increase, rising from 570,000 yuan per kilogram at the beginning of 2023 to 1,700,000 yuan per kilogram by the end of 2024, marking a 198.25% increase [11][12]. - Despite the potential for imported cow bile to stabilize prices, some industry experts remain cautious, suggesting that the high price trend for natural cow bile may not change quickly [15]. - Companies like Tong Ren Tang have expressed a conservative stance regarding the impact of the new policy on cost pressures, indicating that multiple factors will influence the effectiveness of the pilot program [12][13].

截至股权登记日下午上海证券交易所收市后，在中国证券登记结算有限责任公司上海分公司（以下简 称"中国结算上海分公司"）登记在册的本公司全体股东。 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述或者重大遗漏，并对其内容 的真实性、准确性和完整性承担法律责任。 重要内容提示： 本次利润分配方案经公司2025年4月15日的2024年年度股东大会审议通过。 二、分配方案 1.发放年度：2024年年度 2.分派对象： 三、相关日期 ■ 四、分配实施办法 1.实施办法 3.分配方案： 除自行发放的对象外，截至股权登记日登记在册的本公司全体股东的红利委托中国结算上海分公司通过 其资金清算系统向股权登记日上海证券交易所收市后登记在册并在上海证券交易所各会员办理了指定交 易的股东派发。已办理指定交易的投资者可于红利发放日在其指定的证券营业部领取现金红利，未办理 指定交易的股东红利暂由中国结算上海分公司保管，待办理指定交易后再进行派发。 2.自行发放对象 华立医药集团有限公司、华立集团股份有限公司、武汉市江岸区先锋彩印厂及未办理补登记手续的原内 部职工股股东的现金红利由本公司自行发放。 3.扣税说明 （1）对于 ...

Core Viewpoint - The recent announcement by the National Medical Products Administration and the General Administration of Customs to allow the import of natural bezoar for traditional Chinese medicine production has not led to significant market enthusiasm among midstream enterprises, as they continue to face challenges in sales channels and cost pressures [2][3][4]. Group 1: Import Policy and Market Reaction - The import ban on natural bezoar has been lifted, allowing imports from countries free of mad cow disease, with a pilot program set for two years in 12 regions [2]. - Despite the lifting of the ban, stock prices of key companies relying on natural bezoar as a raw material showed minimal increases, with most experiencing declines shortly after the announcement [3]. - The global supply of natural bezoar remains limited, as major exporting countries are not included in the approved list, leading to ongoing supply-demand imbalances [3][6]. Group 2: Supply and Demand Dynamics - Natural bezoar, a rare and expensive traditional Chinese medicine ingredient, has seen its price surge from 170,000 yuan per kilogram in 2016 to around 1.6 million yuan in 2024, reflecting a nearly tenfold increase over nine years [2][5]. - In 2023, China's production of natural bezoar was approximately 5.58 tons, while the demand reached 10.95 tons, indicating a significant supply shortfall [4][5]. - The limited supply is exacerbated by the decline in the number of working cattle and changes in farming practices, which reduce the formation of bezoar [4]. Group 3: Financial Performance of Key Companies - Companies like Tongrentang and Pizhouhuang have reported revenue growth but declining profits due to rising raw material costs, with Tongrentang's net profit down 8.54% year-on-year [9][10]. - Pizhouhuang has also faced challenges, with its core product's price increasing significantly without corresponding profit growth, leading to inventory issues [9][10]. - The retail pharmacy sector is experiencing a contraction, with thousands of stores closing, further complicating the sales environment for these companies [10]. Group 4: Strategic Responses - In response to market challenges, companies are increasing marketing expenditures and opening new stores, but these efforts have not yet translated into substantial revenue growth [11]. - The ongoing inventory issues faced by companies like Tongrentang and Pizhouhuang highlight the shifting preferences in the market, necessitating clinical validation of product efficacy to rejuvenate sales [11].