中国经济网北京10月14日讯 亚太药业（002370.SZ）今日复牌一字涨停，截至发稿，报6.24元，涨 幅10.05%。 本次向特定对象发行股票的发行对象为新控股股东星浩控股，因此本次发行构成关联交易。 截至预案公告日，公司现控股股东为富邦集团，实际控制人为宋汉平、傅才、胡铮辉组成的管理团 队，富邦集团及汉贵投资合计持有公司108,945,566股股份，占公司总股本的14.61%。 2025年10月13日，星浩控股与公司签订附条件生效的《股份认购协议》。同时，公司现控股股东富 邦集团及汉贵投资与星浩控股及星宸投资签署了《股份转让协议》；星浩控股与星宸投资签署了《一致 行动人协议》《表决权委托协议》。 亚太药业昨日晚间披露《2025年度向特定对象发行股票预案》《关于筹划公司控制权变更事项进展 暨公司股票复牌的公告》等公告。 2025年10月13日，公司控股股东富邦集团及一致行动人汉贵投资与浙江星浩控股合伙企业（有限合 伙）（以下简称"星浩控股"）及一致行动人浙江星宸股权投资合伙企业（有限合伙）（以下简称"星宸 投资"）签署了《股份转让协议》。富邦集团和汉贵投资拟通过协议转让方式转让公司14.62%股份，共 计 ...

Group 1 - The core point of the article is that Guilin Sanjin has confirmed the progress of its BC006 monoclonal antibody injection project, which is nearing the completion of Phase I clinical trials and is expected to enter Phase III soon [2] - The company stated that if a significant breakthrough is achieved, it will disclose the information in accordance with the requirements of the Shenzhen Stock Exchange [2]

Core Viewpoint - The controlling shareholder of Asia-Pacific Pharmaceutical will change from Fubon Group to Xinghao Holdings, with the stock resuming trading on October 14, 2025 [2][5]. Shareholder Change - Fubon Group and Hangu Investment plan to transfer 14.62% of shares, totaling 108.9 million shares, at a price of 8.26 CNY per share, amounting to 900 million CNY [4]. - After the transfer, the controlling shareholder will be Xinghao Holdings, and the actual controllers will change to Qiu Zhongxun [4]. Corporate Restructuring - Asia-Pacific Pharmaceutical's board approved the dissolution of its wholly-owned subsidiary, Wuhan Guanggu Asia-Pacific Pharmaceutical, to optimize organizational structure and improve operational efficiency [5]. - The subsidiary will no longer be included in the consolidated financial statements after the dissolution [5]. Fundraising and Investment - The company announced a targeted fundraising plan to issue up to 137 million shares at a price of 5.11 CNY per share, raising a total of up to 700 million CNY [7]. - The funds will be used for new drug research and development projects, including oncolytic virus drug platforms and long-acting formulations [7][8]. - The issuance will not change the company's control but may dilute net asset returns and earnings per share in the short term [7]. Strategic Direction - The company aims to transition from traditional chemical generics to improved new drugs and innovative drug research, enhancing its risk resistance and expanding its product portfolio [8].

Core Viewpoint - The controlling shareholder of Asia-Pacific Pharmaceutical will change from Fubon Group to Xinghao Holdings, with the stock resuming trading on October 14, 2025 [1][3]. Shareholder Control Change - Fubon Group and Hangu Investment plan to transfer 14.62% of the company's shares, totaling 108.9 million shares, at a price of 8.26 CNY per share, amounting to a total of 900 million CNY [2]. - Following the transfer, the controlling shareholder will shift to Xinghao Holdings, and the actual controller will change to Qiu Zhongxun [2]. Stock Resumption and Subsidiary Deregistration - Asia-Pacific Pharmaceutical's stock will resume trading on October 14, 2025 [3]. - The company has approved the deregistration of its wholly-owned subsidiary, Wuhan Optics Valley Asia-Pacific Pharmaceutical Co., Ltd., which will no longer be included in the consolidated financial statements after deregistration [3]. Fundraising and Investment Plans - The company plans to issue up to 137 million shares at a price of 5.11 CNY per share, raising a total of no more than 700 million CNY for new drug research and development projects [4]. - The fundraising will focus on developing oncolytic virus drug platforms, long-acting formulations, and compound formulations, among others [4]. - The issuance will not change the company's control but will increase total share capital and net assets, potentially diluting net asset returns and earnings per share in the short term [4]. Strategic Transition - Through the implementation of the fundraising projects, the company aims to transition from a focus on traditional chemical generics to improved new drugs and first-class innovative drug research and development [5]. - This strategic shift is intended to enhance the company's operational resilience and advance promising new drug projects into critical clinical stages, thereby broadening its product portfolio [5].

于2025年10月13日，星浩控股与上市公司签订附条件生效的《股份认购协议》。同时，上市公司控股股 东富邦集团及其全资子公司汉贵投资与星浩控股及其一致行动人星宸投资签署了《股份转让协议》;星 浩控股与其一致行动人星宸投资签署了《一致行动人协议》《表决权委托协议》。富邦集团及其全资子 公司汉贵投资通过协议转让方式将其合计持有的1.09亿股上市公司股票(占公司总股本的14.61%)转让给 星浩控股及其一致行动人星宸投资;上述股份转让交割后，星宸投资按照《一致行动人协议》约定与星 浩控股保持一致行动，以确保星浩控股对亚太药业的实际控制;星宸投资将其获得的4842.03万股上市公 司股票(占公司总股本的6.49%)对应的全部表决权、召集权、提名和提案权、参会权、监督建议权及除 收益权和股份转让等财产性权利之外的其他权利无条件、不可撤销地委托给星浩控股行使。上市公司的 控股股东变更为星浩控股，实际控制人变更为邱中勋先生。 此外，公司股票自2025年10月14日开市起复牌。 智通财经APP讯，亚太药业(002370.SZ)披露2025年度向特定对象发行股票预案，公司拟向浙江星浩控股 合伙企业(有限合伙)发行股票不超过1. ...

Core Viewpoint - The company has received approval from the National Medical Products Administration for the clinical trial of SQ-129 vitreous sustained-release injection, a modified new drug aimed at treating diabetic macular edema and macular edema caused by retinal vein occlusion [1] Group 1: Product Development - SQ-129 vitreous sustained-release injection is classified as a chemical drug type 2.2 modified new drug [1] - The clinical application is intended for (1) treatment of diabetic macular edema (DME) in adult patients; (2) treatment of macular edema caused by branch retinal vein occlusion (BRVO) or central retinal vein occlusion (CRVO) in adult patients [1] - The company has completed various studies, including pharmaceutical and non-clinical pharmacology and toxicology, demonstrating good safety and clinical development value for SQ-129 [1] Group 2: Market Context - Currently, there are no approved products in the domestic and international markets for SQ-129 [1]

Core Insights - The event "Innovation Source, Health Navigation" highlighted Beijing's focus on the pharmaceutical and health sectors, showcasing how clinical needs and supportive policies drive innovation and economic growth [1][3]. Company Overview - Huahui Anjian (Beijing) Biotechnology Co., Ltd. is a biotech company founded in 2015, focusing on developing "first-in-class" or "best-in-class" drugs, particularly in virology, hepatology, and related oncology fields [3][4]. - The company has six potential "First-in-Class" or "Best-in-Class" drugs in various clinical development stages [3]. Scientific Breakthroughs - The discovery of NTCP (sodium taurocholate co-transporting polypeptide) by Dr. Li Wenhui's team in 2012 was pivotal for developing treatments for hepatitis B and D, marking a significant advancement in the field [3][4]. - Huahui Anjian has developed new drugs HH-0003 and HH-006 based on this discovery, with HH-003 being the world's first neutralizing antibody targeting the PreS1 region of the hepatitis B virus [4]. Regulatory Milestones - HH-003 has received "Breakthrough Therapy" designation from both China's CDE and the FDA, with its New Drug Application (NDA) accepted by the National Medical Products Administration of China, expected to be conditionally approved by late 2025 or early 2026 [4][6]. Talent and Capital Strategy - The company emphasizes a dual approach to talent acquisition, integrating global and local expertise to enhance innovation and commercial operations [6]. - Huahui Anjian's growth is supported by local government and social capital, facilitating the commercialization of HH-003 and the development of other innovative drugs [6][8]. Product Pipeline - Huahui Anjian has established a diversified product matrix centered around the innovative drug HH-003, with iterative products like HH-006 and strategic varieties like HH-1270, creating a comprehensive pipeline [8].

协议主要条款 对公司影响与风险 本次协议签署将加快奥布替尼及其他管线产品全球开发和商业化进程，是国际化战略重要里程碑，预计 对未来业绩产生积极影响，不影响业务独立性，不会形成依赖。但新药研发风险高、周期长，本次交易 付款需满足条件，最终金额存在不确定性，投资者需谨慎决策。 来源：新浪财经-鹰眼工作室 market诺诚健华10月9日发布公告称，其全资子公司InnoCare Pharma Inc.与Zenas BioPharma, Inc.签署授 权许可协议，将奥布替尼及2项临床前资产有偿许可给Zenas，使其可开发、生产、商业化或以其他方式 利用该等产品。 交易详情 交易审议与双方情况 2025年10月7日，诺诚健华董事会审议通过本次交易，无需提交股东大会审议。主要许可产品：奥布替 尼是处于后期临床阶段、具潜在同类最佳优势的高中枢神经系统渗透性、选择性、不可逆口服小分子 BTK抑制剂。在多发性硬化症领域已启动相关III期临床试验；在自身免疫疾病领域，免疫性血小板减少 症三期注册临床完成患者入组，系统性红斑狼疮IIb期临床数据预计于2025年第四季度公布；在血液肿 瘤领域，自中国上市以来已取得显著临床认可及市场覆 ...

2025年10月7日，诺诚健华全资子公司InnoCare Pharma Inc.与美国生物制药公司Zenas BioPharma, Inc.签 署授权许可协议。Zenas将获得奥布替尼等产品多项权利，公司保留部分权利。Zenas支付1亿美元首付 款和近期里程碑付款，授予700万普通股股票，交易总额超20亿美元，公司还可按净销售额收特许权使 用费。协议签署将加快产品全球开发和商业化，预计利好未来业绩。不过，新药研发风险高、周期长， 交易付款有条件，金额存不确定性，投资者需防范风险。 ...

Investment Rating - The report assigns a "Buy" rating for the company, marking its first coverage [2][9]. Core Insights - The company reported a significant increase in revenue and net profit for the first half of 2025, with total revenue reaching 17.52 billion yuan, a 46% increase year-on-year, and a net profit of 450 million yuan compared to a loss of 2.88 billion yuan in the same period last year [5][6]. - The company has raised its full-year revenue guidance from 4.9-5.3 billion USD to 5-5.3 billion USD, while maintaining its guidance for positive GAAP operating profit for the year [5][6]. Financial Performance - In Q2 2025, the company achieved a revenue of 9.47 billion yuan, a 42.7% increase year-on-year, and a net profit of 540 million yuan, compared to a loss of 970 million yuan in the same quarter last year [5][6]. - The global revenue for the drug Zebutinib reached 1.74 billion USD in the first half of 2025, with a year-on-year growth of 54.7%, driven by strong performance in the US and Europe [6][7]. Product Development - The company is advancing its product pipeline, with several key trials underway, including a Phase III trial for a combination therapy involving Zebutinib [7][8]. - The company anticipates significant data releases in the second half of 2025 for various products, including a KRAS inhibitor and ADCs [8]. Earnings Forecast - The company is projected to achieve revenues of 37.1 billion yuan, 47.15 billion yuan, and 58.18 billion yuan for the years 2025, 2026, and 2027, respectively, with corresponding net profits of 820 million yuan, 4.07 billion yuan, and 8.07 billion yuan [9][11].