在全球，超过300万名尿毒症患者长期依赖透析维持生命。他们不仅要忍受反复治疗的痛苦，更因缺乏自我健康管理和透析并发症预防知识，常常延误治 疗时机，影响预期寿命。如何帮助更多患者及时接受规范化治疗，在延长生命周期的同时提升生活质量，已成为医学和社会必须共同面对的课题。 健帆集团创始人、董事长董凡致辞 9月19日，在新华网与健帆集团联合主办的"919尿毒症关爱日"公益发布会上，健帆集团创始人、董事长董凡发表致辞。他回顾了企业二十三年来的发展历 程，强调健帆坚持原研原创与技术推广的双重使命，并提出"医学的使命不仅是延长生命，更是重建生活"。因此，健帆集团提出倡议：将每年的9月19日 设立为"尿毒症关爱日"，希望以此为起点，成为患者感到温暖与支持的节日，让每一位患者不仅要活下去，更要活得好。 从实验室到 临床："透析＋灌流"成为 可及选择 传统血液透析在清除小分子毒素方面效果显著，但难以去除中、大分子毒素。这些毒素的长期蓄积，会导致炎症反应和多种并发症，成为影响患者生存质 量的重要障碍。如何解决透析的"盲区"，曾是全球医学界普遍面临的难题。 健帆集团选择从这一"临床痛点"切入。2004年，健帆研发出全球首款适用于尿毒 ...

健帆生物科技集团股份有限公司 投资者关系活动记录表 编号：2025-004 投 资 者 关 系 活动类别 □ 特定对象调研 □ 分析师会议 □ 媒体采访 √ 业绩说明会 □ 新闻发布会 □ 路演活动 □ 现场参观 □ 其他（线上会议） 参与人员 投资者网上提问 时间 2025 年 9 月 19 日 15:30-17:00 地点 公司通过全景网"投资者关系互动平台"（https://ir.p5w.net）采用网络远程的方 式召开业绩说明会 上 市 公 司 接 待人员姓名 董事长兼总经理 董凡 董事兼财务总监 廖雪云 董事会秘书 黄聪 独立董事 徐焱军 投 资 者 关 系 活 动 主 要 内 容介绍 投资者提出的问题及公司回复情况 公司就投资者在本次说明会中提出的问题进行了回复： 问题 1：公司股价近期下跌的原因是什么？公司管理层和大股东近期有没有 增持、回购公司股票的打算？ 答：您好，感谢您的建议！上市公司股票价格受多方面因素影响，敬请注意 投资风险。公司始终重视投资者利益，近几年已经实施了实控人增持、回购公司 1 股份、现金分红、股权激励计划等多种积极措施，多措并举提振信心。未来如有 相关计划，公司将严格按照 ...

Core Viewpoint - The company reported a decline in revenue and net profit for the first half of 2025, but maintained strong cash flow and profitability metrics, indicating resilience despite market challenges [2][5]. Financial Performance - In the first half of 2025, the company achieved revenue of 1.134 billion yuan, a year-on-year decrease of 24.15% - Net profit was 389 million yuan, down 29.46% compared to the previous year - Operating cash flow was 538 million yuan, exceeding net profit by 149 million yuan, reflecting high-quality cash flow [2]. Business Segment Performance - **Nephrology Sector**: Sales revenue from nephrology products reached 784.97 million yuan, accounting for 69.20% of total revenue. The KHA series products generated 79.98 million yuan in sales, up 27.34% year-on-year, while pHA series sales increased by 374.22% to 11.75 million yuan [3]. - **Hepatology Sector**: Revenue from hepatology products was 131.53 million yuan, representing 11.59% of total revenue [3]. - **Critical Care Sector**: Sales in this area totaled 142.31 million yuan, making up 12.54% of total revenue, with a notable 36.15% increase in sales from the CA series [3]. - **Blood Purification Equipment**: Revenue was 19.34 million yuan, accounting for 1.71% of total revenue [3]. - **International Business**: Overseas revenue reached 34.44 million yuan, representing 3.04% of total revenue, with products used in over 2,000 hospitals across 98 countries [3]. Research and Development - The company invested 97 million yuan in R&D, which is 8.59% of revenue, and obtained 15 new patents during the reporting period [4]. - Two products received CE certification under the latest EU MDR regulations, and a new product for medical waste disposal was registered [4]. Dividend and Social Responsibility - The company distributed a cash dividend of 620 million yuan (including tax), with a payout ratio exceeding 75% [4]. - It contributed 19.17 million yuan in cash and materials for public welfare projects during the reporting period [4]. Future Outlook - The company anticipates a decline in revenue due to price adjustments and high base effects from the previous year, but plans to deepen its focus on blood purification and expand both domestic and international markets [5]. - The company is exploring new business areas related to metabolic cardiovascular diseases and has initiated a clinical study on plasma adsorption in stroke patients [5]. - The company aims to maintain a stable and sustainable dividend policy, having distributed a total of 4.07 billion yuan since its IPO [5].

Financial Performance - In the first half of 2025, the company achieved revenue of 1.134 billion CNY, a year-on-year decrease of 24.15% [1] - Net profit for the same period was 389 million CNY, down 29.46% year-on-year [1] - Operating cash flow was 538 million CNY, exceeding net profit by 149 million CNY, indicating high-quality cash flow [1] - Gross margin stood at 79.82%, while net margin was 34.26%, reflecting strong overall profitability [1] Marketing Progress - In the nephrology sector, sales from kidney disease products reached 784.97 million CNY, accounting for 69.20% of total revenue [2] - The KHA series generated 79.98 million CNY in sales, a 27.34% increase year-on-year, covering over 700 hospitals [2] - The pHA series, launched in November 2023, achieved sales of 11.75 million CNY, with a remarkable growth of 374.22% [2] - In the hepatology sector, sales reached 131.53 million CNY, representing 11.59% of total revenue [2] - The critical care sector generated 142.31 million CNY, accounting for 12.54% of total revenue [3] Research and Development - R&D investment amounted to 97 million CNY, representing 8.59% of total revenue [5] - The company obtained 15 new patents, bringing the total to 393, including 111 invention patents [5] - Two products received CE certification under the new EU MDR regulations, allowing sales in EU countries [5] Dividend Policy - The company distributed a cash dividend of 620 million CNY for the 2024 fiscal year, with a payout ratio exceeding 75% [5] - Cumulative dividends since the company's IPO amount to 4.07 billion CNY, 2.9 times the amount raised through IPO and refinancing [5] Social Responsibility - The company donated cash and materials valued at 19.17 million CNY for charitable projects, reflecting its commitment to social responsibility [5] Future Outlook - The company plans to enhance its focus on the blood purification field and expand its international market presence [8] - It aims to increase the penetration rate of kidney products and improve clinical application frequency [11] - The company is exploring new business areas related to metabolic cardiovascular diseases and health management [15] - Future international business growth will be driven by academic promotion and partnerships with key hospitals [14]

Core Viewpoint - Shandong Weigao Blood Purification Products Co., Ltd. reported a significant increase in revenue and net profit for the first half of 2025, reflecting strong growth in the blood purification industry driven by favorable government policies and increasing healthcare awareness among the population [1][2]. Company Overview and Financial Indicators - The company achieved an operating income of approximately 1.76 billion yuan, representing an 8.52% increase compared to the same period last year [2]. - The total profit reached approximately 264.16 million yuan, a 10.89% increase year-on-year [2]. - The net profit attributable to shareholders was approximately 220.24 million yuan, marking a 10.11% increase from the previous year [2]. - The company's net assets increased by 21.45% to approximately 6.80 billion yuan, and total assets grew by 16.11% to approximately 8.12 billion yuan [2]. Industry Context - The blood purification industry is characterized by high knowledge intensity and capital requirements, making it a crucial part of China's healthcare system [3]. - The treatment penetration rate for End-Stage Renal Disease (ESRD) patients in China is expected to rise significantly, with projections indicating that by 2030, the treatment rates for blood dialysis and peritoneal dialysis will reach 54.29% and 7.53%, respectively [4]. - Recent policies promoting bulk purchasing in the medical device sector are expected to increase industry concentration, leading to the exit of smaller companies and a stronger market position for larger firms [4]. Business Operations - The company specializes in the research, production, and sales of blood purification medical products, including blood dialysis machines and related consumables, and is one of the most comprehensive manufacturers in this field in China [5]. - The company has developed key technologies in blood dialysis, achieving performance metrics that meet or exceed those of leading international brands [5]. - The sales strategy combines direct sales and a robust distribution network, covering over 6,000 hospitals and dialysis centers across China [6][7]. Management and Development - The company has invested approximately 70.18 million yuan in research and development, accounting for 3.98% of its operating income, and has obtained multiple patents to enhance its technological edge [9][10]. - The management has focused on improving compliance, operational management, and digital transformation to enhance efficiency and risk management [8][9]. - The company aims to expand its market presence both domestically and internationally, with a strategic focus on becoming a leading global provider of blood purification solutions [10][11].

Core Viewpoint - The report outlines the ongoing supervisory work conducted by Western Securities for Chongqing Mountain Outside Blood Purification Technology Co., Ltd. (Mountain Outside), emphasizing compliance with regulations and the company's operational status post-IPO [1][2]. Group 1: Supervisory Work - The sponsor has established and effectively implemented a continuous supervision work system, creating specific work plans for ongoing oversight [1]. - A continuous supervision agreement was signed between the sponsor and Mountain Outside, clarifying the rights and obligations of both parties during the supervision period [1]. - The sponsor conducts regular communication, visits, and on-site inspections to understand Mountain Outside's business situation [1][2]. Group 2: Financial Performance - For the first half of 2025, the company reported operating income of CNY 357.25 million, a year-on-year increase of 28.72% [14]. - The total profit reached CNY 60.14 million, reflecting a growth of 34.55% compared to the previous year [14]. - The net profit attributable to shareholders was CNY 55.04 million, marking a 20.28% increase year-on-year [14]. Group 3: Research and Development - The company increased its R&D investment by 37.12% in the first half of 2025, totaling CNY 36.51 million, which represents 10.22% of its operating income [24][25]. - The R&D team expanded to 236 personnel, a growth of 38.01% compared to the previous year [24]. - The company has obtained various patents and certifications, including 62 invention patents and CE certifications for several products, enhancing its competitive edge in the market [19][25]. Group 4: Market Position and Competition - Mountain Outside is positioned as a leading domestic manufacturer of blood purification equipment, benefiting from technological advantages and brand recognition [14][16]. - The company faces competition from established international brands, necessitating continuous innovation and product upgrades to maintain market share [11][12]. - The domestic market for blood purification devices is characterized by intense competition, with imported brands holding significant market shares [11][12]. Group 5: Risk Factors - The company is exposed to various risks, including core competitiveness risks related to technology and talent retention, operational risks associated with regulatory compliance, and financial risks linked to accounts receivable [4][9][10]. - The potential impact of changes in national healthcare policies and market dynamics poses additional challenges to the company's growth and profitability [12][13]. - The company is actively monitoring macroeconomic conditions and trade relations to mitigate risks associated with currency fluctuations and global trade disputes [13].

Core Viewpoint - Sanxin Medical (300453) emphasizes its commitment to an innovation-driven development strategy, focusing on a comprehensive product range for various blood purification treatment modalities [1] Product Development - The company has established a complete product system for end-stage renal disease blood purification, including hemodialysis, hemofiltration, and Continuous Renal Replacement Therapy (CRRT) [1] - Hemodialysis products include hemodialysis machines, dialyzers, dialysis concentrates, dialysis tubing, and disposable dialysis catheters, with ongoing upgrades to address patient pain points [1] - Hemofiltration products consist of hemofiltration machines, hemofiltration filters, and blood purification infusion tubing [1] - CRRT products include CRRT tubing and accessories, with accelerated development of CRRT equipment [1]

Core Insights - The company reported a revenue of 357 million yuan for the first half of 2025, representing a year-on-year growth of 28.72% [1] - The net profit attributable to shareholders reached 55.0386 million yuan, with a year-on-year increase of 20.28% [1] - The basic earnings per share stood at 0.1713 yuan [1] Revenue Growth - The increase in revenue was driven by a continuous rise in market share for the company's products [1] - Sales revenue from blood purification equipment showed steady growth [1] - There was a significant increase in sales revenue from self-produced blood purification consumables [1]

Investment Rating - The report assigns a "Buy-A" investment rating to the company with a 6-month target price of 22.51 CNY, compared to the current stock price of 17.86 CNY [4]. Core Insights - The blood purification industry is experiencing sustained growth, providing a solid foundation for the company's expansion. The number of chronic kidney disease patients globally reached 4.1 million in 2023, with a compound annual growth rate (CAGR) of approximately 5% over the past decade. In China, the total number of dialysis patients is expected to reach 1.02 million by 2024, with a CAGR of about 12% [1][26]. - The company's revenue from equipment is closely correlated with the demand for terminal bidding, which has shown significant recovery in 2023 after a downturn in 2024 due to industry adjustments and procurement delays. The company is expected to see a continued improvement in its financial performance starting from Q1 2025 [2][39]. - Long-term growth is supported by an increase in market share for equipment, significant contributions from consumables, and accelerated international expansion. The company has improved its market share in blood dialysis equipment to 18% in terms of volume and 17% in terms of value by mid-2025, positioning itself as a strong competitor against foreign giants [3][50]. Summary by Sections 1. Blood Purification Industry Growth - The global market for blood dialysis services and products reached 81 billion euros in 2023, with China's dialysis product market expected to approach 30 billion CNY by 2025, reflecting a steady growth trend [1][30]. 2. Short-term Catalysts - The demand for blood dialysis equipment has rebounded significantly in 2023, leading to a substantial increase in the company's revenue and profit. The recovery trend is expected to continue into 2025, driven by improved bidding conditions [2][39]. 3. Long-term Growth Drivers - The company has enhanced its market share in blood dialysis equipment, achieving a notable increase in its bidding share from 13% in 2024 to 18% in 2025. The contribution from self-produced consumables has also seen rapid growth, with a 208.15% increase in sales revenue in 2024 [3][4]. - The company's international sales reached 128 million CNY in 2024, marking a 29.74% year-on-year growth, particularly in emerging markets such as South America and Africa [9][10]. 4. Financial Projections - The company is projected to achieve revenue growth rates of 33.7%, 16.1%, and 15.2% for the years 2025 to 2027, with net profit growth rates of 126.7%, 24.6%, and 20.4% respectively, indicating strong growth potential [10][12].

Group 1: Company Overview and Financial Performance - The company achieved operating revenue of 760.81 million yuan, a year-on-year increase of 10.83% [2] - Net profit attributable to shareholders reached 115.12 million yuan, up 8.35% from the previous year [2] - The net profit excluding non-recurring gains and losses was 103.23 million yuan, reflecting a growth of 9.26% [2] - Blood purification products generated revenue of 625.59 million yuan, a 19.73% increase, accounting for 82.23% of total revenue [2][3] - Revenue from drug delivery devices decreased by 15.06% to 82.41 million yuan, representing 10.83% of total revenue [3] - Revenue from cardiothoracic products was 34.98 million yuan, a slight increase of 0.74%, making up 4.60% of total revenue [3] Group 2: International Market Expansion - The company has accelerated its internationalization, successfully registering products in countries like Indonesia, Peru, and Mexico [4] - Overseas revenue reached 187.00 million yuan, a significant increase of 67.30% [4] - Blood purification product exports accounted for 88% of total export revenue, with sales increasing by 83.84% [4] - The company focuses on emerging markets along the "Belt and Road" initiative, which have a large and growing population [4] Group 3: Product Innovation and Development - The company is enhancing its product range in blood purification and expanding into diabetes and early-stage kidney disease management [5] - Innovative medical devices and high-value consumables are under development, with several projects receiving provincial support [5][6] - The company has developed a disposable blood dialysis catheter, which has gained market approval and is expected to improve patient safety and experience [8][10] Group 4: Market Challenges and Strategies - The drug delivery device market is facing increased competition and product homogeneity, leading to a 15% decline in revenue [10] - The company plans to innovate and upgrade drug delivery devices to meet rising clinical demands for safety and precision [10] - The blood dialysis product procurement process has expanded nationwide, benefiting domestic manufacturers [11] Group 5: Fundraising and Future Plans - The company plans to issue convertible bonds to raise up to 530 million yuan for expanding production capacity and enhancing financial stability [12][13] - The funds will support projects including the annual production of 10 million blood dialysis membranes and 10 million blood dialysis devices [13]