据北交所官网信息，9月30日，四川睿健医疗科技股份有限公司（下称"睿健医疗"）披露北交所针对公司IPO的第二轮审核问询函（以下简称二轮问询）。在 二轮问询中，北交所就公司IPO材料中关联交易公允性、销售费用真实性、研发资本化合规性、经销商终端销售穿透核查充分性、境外股权架构稳定性等问 题作出问询。 此外，9月30日，睿健医疗因财务报告到期补充审计事项申请中止审核，北交所根据相关规定中止其公开发行股票并上市审核，睿健医疗最新IPO进程显示 为"中止"。 | 序号 | 原因 | 披露日期 | | --- | --- | --- | | | 2025年9月30日，睿健医疗因财务报告到期补充审计事项申请中止审核，根据 | | | | 《北京证券交易所向不特定合格投资者公开发行股票并上市审核规则》第五十 | 2025-09-3 | | | 二条,中止其公开发行股票并上市审核。 | | 北交所请公司：①全面梳理王滔具有重大影响相关交易主体的具体情况，包括与公司开展合作以来的相关主体的成立时间、股权结构、实际控制人、主要经 营管理人员、注销时间及原因（如涉及）、王滔重大影响的具体体现、经营规模及公司的交易占比、与公司的合作 ...

深圳商报·读创客户端记者 马强 | 序号 | 原因 | 披露日期 | | --- | --- | --- | | | 2025年9月30日，睿健医疗因财务报告到期补充审计事项申请中止审核，根据 | | | | 《北京证券交易所向不特定合格投资者公开发行股票并上市审核规则》 第五十 | 2025-09-3 | | | 二条,中止其公开发行股票并上市审核。 | | 招股书显示，睿健医疗成立于2013年，是一家专业从事血液净化产品的研发、生产和销售的企业。公司主要产品包括血液透析器和血液灌流器，2024年公司 取得了血液透析机、连续性血液净化设备和连续性肾脏替代治疗管路等产品的医疗器械注册证，公司产品可以覆盖血液透析环节主要设备和耗材。 ▍关联交易真实公允性：向印度乐普销售毛利率低、账期长，是否存利益输送嫌疑？ 据北交所官网信息，9月30日，四川睿健医疗科技股份有限公司（下称"睿健医疗"）披露北交所针对公司IPO的第二轮审核问询函（以下简称二轮问询）。在 二轮问询中，北交所就公司IPO材料中关联交易公允性、销售费用真实性、研发资本化合规性、经销商终端销售穿透核查充分性、境外股权架构稳定性等问 题作出问询。 此外，9 ...

（编辑 王雪儿） 证券日报网讯 健帆生物9月30日在互动平台回答投资者提问时表示，2024年度公司高通量、低通量血液 透析器通过集采实现的销售收入为962万元，占同期营业收入的0.36%；血液透析管路通过集采实现销 售收入336万元，占同期营业收入的0.13%。2025年上半年公司高通量、低通量血液透析器通过集采实 现销售收入1520万元，占同期营业收入的1.34%；血液透析管路通过集采实现销售收入245万元，占同 期营业收入的0.22%。截至目前，公司主营产品血液灌流器产品未被纳入国家及省级等集中带量采购范 围。 ...

（记者 胡玲） 健帆生物（300529.SZ）9月30日在投资者互动平台表示，（1）2024年度公司高通量、低通量血液透析 器通过集采实现的销售收入为962万元，占同期营业收入的0.36%；血液透析管路通过集采实现销售收 入336万元，占同期营业收入的0.13%。2025年上半年公司高通量、低通量血液透析器通过集采实现销 售收入1520万元，占同期营业收入的1.34%；血液透析管路通过集采实现销售收入245万元，占同期营 业收入的0.22%。截至目前，公司主营产品血液灌流器产品未被纳入国家及省级等集中带量采购范围。 （2）2025年上半年公司海外市场实现收入3443.76万元，占公司收入的3.04%。未来公司将持续高度重 视国际市场开拓，通过积极开展跨国科研合作、梳理海外经销商体系、招募海外推广人员、聚焦重点国 家等策略，深挖海外市场机会，实现国际业务"慢病+急危病"双轮驱动，打开国际业务增长新局面。 每经AI快讯，有投资者在投资者互动平台提问：董秘你好，1、请问公司血液透析器和血液透析管路集 采量占去年总销售量比例？折价多少？集采对公司业绩的影响预计如何？2、公司的海外销售进展如 何？ ...

健帆生物科技集团股份有限公司 投资者关系活动记录表 编号：2025-004 投 资 者 关 系 活动类别 □ 特定对象调研 □ 分析师会议 □ 媒体采访 √ 业绩说明会 □ 新闻发布会 □ 路演活动 □ 现场参观 □ 其他（线上会议） 参与人员 投资者网上提问 时间 2025 年 9 月 19 日 15:30-17:00 地点 公司通过全景网"投资者关系互动平台"（https://ir.p5w.net）采用网络远程的方 式召开业绩说明会 上 市 公 司 接 待人员姓名 董事长兼总经理 董凡 董事兼财务总监 廖雪云 董事会秘书 黄聪 独立董事 徐焱军 投 资 者 关 系 活 动 主 要 内 容介绍 投资者提出的问题及公司回复情况 公司就投资者在本次说明会中提出的问题进行了回复： 问题 1：公司股价近期下跌的原因是什么？公司管理层和大股东近期有没有 增持、回购公司股票的打算？ 答：您好，感谢您的建议！上市公司股票价格受多方面因素影响，敬请注意 投资风险。公司始终重视投资者利益，近几年已经实施了实控人增持、回购公司 1 股份、现金分红、股权激励计划等多种积极措施，多措并举提振信心。未来如有 相关计划，公司将严格按照 ...

Core Viewpoint - The report outlines the ongoing supervisory work conducted by Western Securities for Chongqing Mountain Outside Blood Purification Technology Co., Ltd. (Mountain Outside), emphasizing compliance with regulations and the company's operational status post-IPO [1][2]. Group 1: Supervisory Work - The sponsor has established and effectively implemented a continuous supervision work system, creating specific work plans for ongoing oversight [1]. - A continuous supervision agreement was signed between the sponsor and Mountain Outside, clarifying the rights and obligations of both parties during the supervision period [1]. - The sponsor conducts regular communication, visits, and on-site inspections to understand Mountain Outside's business situation [1][2]. Group 2: Financial Performance - For the first half of 2025, the company reported operating income of CNY 357.25 million, a year-on-year increase of 28.72% [14]. - The total profit reached CNY 60.14 million, reflecting a growth of 34.55% compared to the previous year [14]. - The net profit attributable to shareholders was CNY 55.04 million, marking a 20.28% increase year-on-year [14]. Group 3: Research and Development - The company increased its R&D investment by 37.12% in the first half of 2025, totaling CNY 36.51 million, which represents 10.22% of its operating income [24][25]. - The R&D team expanded to 236 personnel, a growth of 38.01% compared to the previous year [24]. - The company has obtained various patents and certifications, including 62 invention patents and CE certifications for several products, enhancing its competitive edge in the market [19][25]. Group 4: Market Position and Competition - Mountain Outside is positioned as a leading domestic manufacturer of blood purification equipment, benefiting from technological advantages and brand recognition [14][16]. - The company faces competition from established international brands, necessitating continuous innovation and product upgrades to maintain market share [11][12]. - The domestic market for blood purification devices is characterized by intense competition, with imported brands holding significant market shares [11][12]. Group 5: Risk Factors - The company is exposed to various risks, including core competitiveness risks related to technology and talent retention, operational risks associated with regulatory compliance, and financial risks linked to accounts receivable [4][9][10]. - The potential impact of changes in national healthcare policies and market dynamics poses additional challenges to the company's growth and profitability [12][13]. - The company is actively monitoring macroeconomic conditions and trade relations to mitigate risks associated with currency fluctuations and global trade disputes [13].

Investment Rating - The report maintains an "Outperform" rating for the pharmaceutical and biotechnology sector [5] Core Insights - The blood purification device industry is benefiting from an aging population and increasing treatment penetration rates, with hemodialysis being the primary treatment for end-stage renal disease (ESRD) [2][12] - The domestic substitution trend in the blood purification device industry is accelerating, with local brands gradually rising to compete with foreign brands [2][33] - The market for blood purification devices is expected to grow significantly, driven by the increasing number of ESRD patients and the low treatment penetration rate in China compared to developed countries [17][19] Summary by Sections Market Performance - The pharmaceutical sector outperformed the overall market, with a 2.21% increase in the biopharmaceutical sector, while the total A-share market declined by 0.05% [1][60] - The TTM price-to-earnings ratio for the biopharmaceutical sector is 34.03x, which is at the 69.61% percentile of the historical valuation over the past five years [1][67] Industry Analysis - The global ESRD patient population is projected to grow from 1113.86 million in 2023 to 1328.60 million by 2027, with a compound annual growth rate (CAGR) of 4.51% [17] - In China, the number of ESRD patients receiving dialysis treatment is significantly lower than in developed countries, indicating substantial growth potential for treatment penetration [19][30] Competitive Landscape - Foreign brands dominate the blood purification device market, with companies like Fresenius and Baxter holding significant market shares, but local brands are increasingly gaining ground [33][37] - Major domestic players include Weigao Blood Purification, Shanda Mountain, and Jianfan Biological, which are expanding their market presence through innovation and product development [33][41][45] Company Forecasts and Ratings - Major companies in the sector, such as Mindray Medical and WuXi AppTec, are rated as "Outperform" with strong projected earnings growth over the next few years [4][71] - Weigao Blood Purification is expected to generate revenue of 36.04 billion yuan in 2024, with a leading market share in blood purification devices [38][41]

Group 1 - The report highlights the selection of 94 companies in the North Exchange, covering various sectors including high-end equipment manufacturing, TMT, chemical new materials, consumption, and biomedicine, with a focus on new productivity companies [2][11][19] - The report emphasizes the importance of specialized and innovative companies, particularly "little giant" enterprises, in driving the new productivity construction [2][3][19] - The five selected companies for this report are Ruijian Medical, Kanghua Co., Tongbao Optoelectronics, Zuxing New Materials, and Peicheng Technology, with an average revenue of 626 million yuan and an average net profit of 95.72 million yuan for 2024 [4][19][20] Group 2 - Ruijian Medical specializes in blood purification products, achieving a revenue of 483 million yuan and a net profit of 127.93 million yuan in 2024, with a gross margin of 51.05% [4][28][30] - Kanghua Co. focuses on POCT in vitro diagnostics, reporting a revenue of 728 million yuan and a net profit of 125.07 million yuan in 2024, with a gross margin of 66.68% [4][35][40] - Tongbao Optoelectronics, which specializes in automotive lighting components, achieved a revenue of 588 million yuan and a net profit of 83.09 million yuan in 2024, reflecting an 11.02% increase in revenue [4][39][40] - Zuxing New Materials is an internationally recognized aluminum pigment manufacturer, with a revenue of 707 million yuan and a net profit of 58.72 million yuan in 2024 [5][39][40] - Peicheng Technology, a third-party BMS "little giant," reported a revenue of 733 million yuan and a net profit of 93.44 million yuan in 2024 [5][39][40]

Core Viewpoint - The blood purification market in China is experiencing significant growth, driven by an increasing number of patients with uremia and an aging population, with a projected annual growth rate of 15% [2] Group 1: Market Overview - The blood purification market in China is expected to grow from 11.6 billion in 2019 to 21.1 billion by 2025, and reach 51.515 billion by 2030, indicating substantial growth potential [2] - The company Weigao Blood Purification holds a leading market share in blood dialysis devices, with 32.5% in blood dialysis filters and 31.8% in blood dialysis tubing, and a second position in dialysis machines with a 24.6% market share [2] Group 2: Financial Performance - Weigao Blood Purification's revenue from 2022 to 2024 is projected to be 3.426 billion, 3.532 billion, and 3.604 billion respectively, with net profits of 315 million, 442 million, and 449 million, demonstrating stable growth [3] - The net profit growth in 2023 was 40.36%, followed by a slight increase of 1.65% in 2024, aligning with the industry's strategy of "volume for price" under the background of centralized procurement [3] Group 3: Company Overview - Weigao Blood Purification is the fourth listed company under Weigao Group, focusing on the research, production, and sales of blood purification medical products, covering the entire industry chain of blood dialysis and peritoneal dialysis [5] - The company collaborates with international firms like Nikkiso and Terumo to enhance the technology level of high-end products [5] Group 4: Product Line Development - The company launched its first self-developed blood dialysis filter in 2005, breaking the overseas monopoly, and has since introduced various innovative products, including the first polysulfone membrane dialysis filter in 2008 and the high-flux HF series in 2013 [6][8] - Blood dialysis tubing sales increased from 30.06 million sets in 2022 to 39 million sets in 2024, with revenue rising from 414 million to 495 million, marking a growth of approximately 29.74% [9]

Core Viewpoint - The financial performance of Jianfan Biological shows a strong growth in 2024, but a significant decline in Q1 2025 raises concerns about the sustainability of its pricing strategy and reliance on a single product line [1][2]. Financial Performance - In 2024, Jianfan Biological achieved a revenue of 2.677 billion yuan, a year-on-year increase of 39.27%, and a net profit of 820 million yuan, up 87.91% [1]. - The first quarter of 2025 saw a revenue drop to 548 million yuan, a decline of 26.40%, and a net profit decrease to 189 million yuan, down 33.71% [1]. Product and Market Dynamics - The blood purification market shows strong demand, with Jianfan's blood perfusion devices generating 2.504 billion yuan in sales in 2024, a 59.58% increase, accounting for 93.6% of total revenue [3]. - The company has initiated a price reduction strategy, lowering the price of its main product by 26%, which led to a significant increase in sales volume [3][4]. Business Structure and Risks - Jianfan Biological's heavy reliance on blood perfusion devices poses risks, as changes in policy, technology, or market demand could impact operations [4]. - The company is transitioning from a single-product dependency to a diversified product portfolio, including differentiated products in the nephrology field and new growth areas in hepatology and critical care [5]. International Expansion - Jianfan has made strides in international markets, obtaining product approvals in 98 countries, with overseas revenue reaching 59.36 million yuan, representing only 2.2% of total revenue [6]. - The company faces challenges in overcoming technical recognition differences and certification barriers in foreign markets [6]. Competitive Landscape - The potential inclusion of blood perfusion products in centralized procurement could pressure prices, although the company believes that quality and technological leadership will be considered in future procurement policies [7]. - The competitive environment is intensifying, with over 14 domestic companies and international giants entering the blood perfusion market, challenging Jianfan's market share [7]. Future Outlook - For 2025, Jianfan plans to focus on deepening its presence in the domestic blood purification market while expanding internationally, particularly in liver disease and critical care markets [8]. - The company aims to explore new applications for blood perfusion technology in sub-health areas and seek quality acquisition targets through capital market tools [8].