截至该公告日期，该款疫苗成为中国首款且唯一一款获批上市的全人群全剂量三价流感病毒亚单位疫 苗。该产品在传统病毒裂解疫苗的基础上进行重大升级，具有保护全面、组分抗原纯度高、不良反应风 险低等优势。 2月13日，恒生指数公司宣布截至2025年12月31日之恒生指数系列季度检讨结果，其中中慧生物- B(02627)获纳入恒生综合指数。变动将于2026年3月6日(星期五)收市后实施并于2026年3月9日(星期一) 起生效，届时沪深交易所会相应调整港股通可投资标的范围。据中金研报，中慧生物-B有可能被调入港 股通，因其满足了包括市值、流动性和上市时间等在内的一系列标准。 中慧生物-B(02627)发布公告，中国国家药品监督管理局已批准本集团针对所有年龄组别的三价流感病 毒亚单位疫苗的新药申请。 ...

Major Events - Lanke Technology (06809) will conduct an IPO from January 30 to February 4, with an expected listing on February 9 [1] - Aixin Yuanzhi (00600) will conduct an IPO from January 30 to February 5, with an expected listing on February 10 [1] - Lexin Outdoor (02720) will conduct an IPO from January 31 to February 5, raising HKD 130 million from Horizon Capital and Huangshan Dejun [1] - Dongpeng Beverage (09980) sets the offer price at HKD 248 per share [1] - Zhonghui Biotech-B (02627) received approval from the National Medical Products Administration for a trivalent influenza virus subunit vaccine [1] - Kangzheng Pharmaceutical (00867) received approval for the first and only targeted drug for vitiligo treatment in China [1] - Shishi Pharmaceutical Group (02005) received production registration for Propafenone Hydrochloride Injection from the National Medical Products Administration [1] - China Aluminum (02600) plans to jointly acquire 68.6% of Brazilian Aluminum from Rio Tinto and will initiate a mandatory offer [1] - Yanzhou Coal Mining (01171) plans to transfer 100% equity of Inner Mongolia Xintai Coal [1] - Botai Car Union (02889) plans to collaborate with Ping An Property & Casualty to reconstruct the smart travel insurance ecosystem [1] - Jin Jing New Energy (01783) signed a strategic framework agreement with Tianqi Grand for lithium battery recycling and precious metal extraction [1] - Guangdong-Hong Kong-Macau Holdings (01396) subsidiary Hongce Data introduces Fudian Capital as a strategic investor for 40% equity [1] - China Mobile (00941), China Unicom (00762), and China Telecom (00728) will adjust the applicable scope of value-added tax for telecom services [1] Operating Performance - BYD Company (01211) sold approximately 210,000 new energy vehicles in January [2] - Geely Automobile (00175) reported total vehicle sales of 270,200 units in January, a year-on-year increase of about 1% [2] - Chery Automobile (09973) saw total sales of 191,500 vehicles in January, a year-on-year decrease of about 10.7% [2] - Seres (09927) reported total vehicle sales of 45,900 units in January, a year-on-year increase of 104.85% [2] - Great Wall Motors (02333) sold approximately 90,300 vehicles in January, a year-on-year increase of 11.59% [2] - Li Auto-W (02015) delivered 27,668 new vehicles in January, a year-on-year decrease of 7.5% [2] - NIO-SW (09866) delivered 27,182 vehicles in January, a year-on-year increase of 96.1% [2] - GAC Group (02238) reported vehicle sales of 116,600 units in January, a year-on-year increase of 18.47% [2] - Great Wall Motors (02333) released a preliminary report indicating a net profit attributable to shareholders of 9.912 billion yuan for 2025, a year-on-year decrease of 21.71% [2] - Shandong Gold (01787) expects a net profit attributable to shareholders of approximately 4.6 billion to 4.9 billion yuan for 2025, a year-on-year increase of 56% to 66% [2] Earnings Forecast - SF Express (09699) expects a year-on-year profit increase of no less than 80% for 2025 [3] - China International Capital Corporation (03908) anticipates a net profit attributable to shareholders of 8.542 billion to 10.535 billion yuan for 2025, a year-on-year increase of 50% to 85% [3] - China Shenhua (01088) expects a year-on-year decline in net profit for 2025 [3] - Datang Power (00991) anticipates a net profit of approximately 6.8 billion to 7.8 billion yuan for 2025, a year-on-year increase of about 51% to 73% [3] - China Southern Airlines (01055) expects a net profit attributable to shareholders of 800 million to 1 billion yuan for 2025, turning a profit [3] - Air China (00753) warns of a net loss attributable to shareholders of approximately 1.3 billion to 1.9 billion yuan for 2025 [3] - China Eastern Airlines (00670) warns of a net loss attributable to shareholders of approximately 1.3 billion to 1.8 billion yuan for 2025 [3] - GAC Group (02238) expects a net loss attributable to shareholders of 8 billion to 9 billion yuan for 2025 [3] - Ansteel (00347) warns of a net loss attributable to shareholders of approximately 4.077 billion yuan for 2025, a year-on-year narrowing of 42.75% [3] - Junshi Biosciences (01877) warns of a net loss attributable to shareholders of approximately 873 million yuan for 2025, a year-on-year decrease of about 31.85% [3]

Company News - Great Wall Motors (02333.HK) expects a total revenue of RMB 222.79 billion in 2025, representing a year-on-year increase of 10.19%. However, net profit is projected to decline by 21.71% to RMB 9.912 billion due to increased investments in new user channels and marketing for new models and technologies [2] - China Southern Airlines (01055.HK) anticipates turning a profit in 2025, with net profit expected to be between RMB 800 million and RMB 1 billion [2] - CICC (03908.HK) forecasts a net profit of RMB 8.542 billion to RMB 10.535 billion in 2025, reflecting a year-on-year increase of 50% to 85% [3] - Datang Power (00991.HK) projects a net profit of approximately RMB 6.8 billion to RMB 7.8 billion in 2025, indicating a year-on-year increase of about 51% to 73% [4] - Rongchang Bio (09995.HK) expects 2025 revenue of approximately RMB 3.25 billion, a year-on-year increase of about 89%, and a net profit of around RMB 716 million, achieving profitability [4] - Haijia Medical (06078.HK) anticipates revenue of approximately RMB 4.0 billion to RMB 4.05 billion in 2025, a year-on-year decrease of about 9% to 10%, with net profit expected to decline by 66% to 76% to around RMB 140 million to RMB 200 million [4] - Junshi Biosciences (01877.HK) expects 2025 revenue of around RMB 2.5 billion, a year-on-year increase of approximately 28.32%, with a net loss of about RMB 873 million, a reduction of 31.85% compared to the previous year [4] - Kaisa New Energy (01108.HK) issued a profit warning, expecting a year-on-year increase in net loss of approximately RMB 90.07 million to RMB 290 million [4] - Xingye Alloy (00505.HK) issued a profit warning, anticipating a year-on-year decrease in profit attributable to equity shareholders of about 50% [4] - Fudan Zhangjiang (01349.HK) issued a profit warning, expecting a net loss of approximately RMB 120 million to RMB 180 million in 2025 [4] - Chenming Paper (01812.HK) issued a profit warning, expecting a net loss of RMB 8.2 billion to RMB 8.8 billion, a significant increase compared to the previous year [5] - Tianqi Lithium (09696.HK) has commenced production of the first batch of standard chemical-grade lithium concentrate products from its third-phase expansion project [6] Financing and Buyback Activities - Xiaomi Group-W (01810.HK) repurchased approximately 4.2 million shares for about HKD 150 million, with repurchase prices ranging from HKD 35.13 to HKD 42.50 [10] - Vitasoy International (00345.HK) repurchased shares worth HKD 24.37 million, acquiring 3.492 million shares at prices between HKD 6.9 and HKD 7 [11] - Yujian Xiaomian (02408.HK) plans to repurchase up to HKD 100 million of H-shares [12] - Nanshan Aluminum International (02610.HK) completed a placement of 31 million shares, raising approximately HKD 1.987 billion [12]

Core Viewpoint - Zhonghui Biotech-B (02627) has achieved a significant milestone with the approval of China's first and only trivalent subunit influenza virus vaccine for the entire population, enhancing its product matrix in the subunit influenza vaccine sector [1][4]. Group 1: Product Development and Market Position - The company previously launched the first and only quadrivalent subunit influenza vaccine (Hui Er Kang Xin) for the entire population, establishing a comprehensive product matrix that meets diverse public health needs and market preferences [4]. - The successful approval of the trivalent vaccine is expected to drive the company's performance and value reassessment, as it aligns with the growing demand for influenza vaccination in China, where the vaccination rate is significantly lower than in the U.S. [5][6]. - The trivalent subunit vaccine is designed to have high antigen purity and fewer adverse reactions, making it particularly suitable for vulnerable populations such as children and the elderly [6]. Group 2: Financial Performance and Market Dynamics - Following the commercialization of the quadrivalent vaccine, the company has seen rapid revenue growth, with projected revenues increasing from 52.168 million yuan in 2023 to 260 million yuan in 2024, and a staggering 918.91% year-on-year growth in the first half of 2025 [7]. - The quadrivalent vaccine has achieved a 100% approval rate for product batch issuance and has expanded its sales network to over 1,100 disease control centers across 30 provinces in China [7]. - The company has also made progress in market access, with the quadrivalent vaccine passing preliminary review for inclusion in the 2025 National Commercial Health Insurance innovative drug list, which is expected to alleviate market promotion pressures [7]. Group 3: Future Growth and R&D Pipeline - The company is actively expanding its product offerings, including a clinical trial for an adjuvanted vaccine targeting individuals aged 65 and older, and research for a vaccine specifically for pregnant women, which could fill a current gap in immunization for infants aged 0-6 months [8]. - The company has a robust R&D pipeline, with multiple promising products under development, including a freeze-dried rabies vaccine and other vaccines targeting pneumonia and shingles, ensuring long-term sustainable growth [9][10]. - The company is also expanding its international market presence, with plans to enter markets in Canada, Singapore, Mexico, and Hong Kong by 2026, leveraging the seasonal differences in influenza activity across regions [11]. Group 4: Market Outlook and Investment Potential - Analysts predict that the company will achieve profitability by 2027, with projected revenues of 798 million yuan and 1.24 billion yuan in 2026 and 2027, respectively, indicating a clear growth trajectory [11]. - The successful approval of the trivalent influenza vaccine is expected to provide immediate revenue growth and enhance the company's competitive advantage in the high-potential subunit vaccine sector [11].

近日，中慧生物-B(02627)迎来又一项里程碑式进展——全国首款且唯一的全人群三价流感病毒亚单位 疫苗成功获批上市。 此前，公司的四价流感亚单位疫苗(慧尔康欣®)已率先实现全人群覆盖，成为中国首款且唯一一款获批 上市的全人群全剂量四价流感病毒亚单位疫苗。此次三价疫苗的成功获批，标志着公司在亚单位流感疫 苗这一优势赛道构建起更加全面的产品矩阵，不仅能够灵活适配多元化的公共卫生需求与市场偏好，也 将为公司业绩的持续兑现与价值重估注入强劲动力。 与此同时，随着中慧生物被纳入新一轮港股通标的名单，市场对公司的关注度亦出现明显提升。自1月 13日以来，公司股价强势上行，突破50港元关口，近十个交易日累计上涨26.47%，成交量同步显著放 大，显示增量资金正持续流入。在产品获批的利好消息驱动下，公司流动性预期持续改善，有望进一步 强化公司在资本市场的吸引力。 前瞻布局亚单位疫苗技术路线 精准填补流感疫苗市场空白 当前，全球流感活动强度持续走高，而我国流感疫苗接种率仍远低于国际水平，这一巨大差距构成了长 期的结构性增长空间。 世卫组织报告显示，自2025年10月以来，全球流感活动强度持续攀升，甲型H3N2亚型流感病毒K亚 ...

智通财经APP讯，中慧生物-B(02627)发布公告，中国国家药品监督管理局已批准本集团针对所有年龄组 别的三价流感病毒亚单位疫苗的新药申请。 截至本公告日期，该款疫苗成为中国首款且唯一一款获批上市的全人群全剂量三价流感病毒亚单位疫 苗。该产品在传统病毒裂解疫苗的基础上进行重大升级，具有保护全面、组分抗原纯度高、不良反应风 险低等优势。 ...

Core Viewpoint - Zhonghui Biotech-B (02627) has received approval from the National Medical Products Administration of China for its trivalent influenza virus subunit vaccine, making it the first and only approved vaccine for all age groups in China [1] Group 1 - The vaccine is a significant upgrade over traditional virus split vaccines, offering comprehensive protection, high purity of antigen components, and a lower risk of adverse reactions [1]

Core Viewpoint - The announcement highlights that Zhonghui Biotech-B (02627.HK) has received approval from the National Medical Products Administration for its trivalent influenza virus subunit vaccine, making it the first and only vaccine approved for all age groups in China [1] Group 1: Product Approval - The trivalent influenza virus subunit vaccine is now approved for all age groups, marking a significant milestone for the company [1] - This vaccine is the first and only one in China that has been approved for the entire population and all dosage levels [1] Group 2: Product Advantages - The vaccine represents a major upgrade over traditional virus split vaccines, offering comprehensive protection [1] - It features high purity of antigen components and a lower risk of adverse reactions [1]

Core Viewpoint - Jiangsu Zhonghui Yuantong Biotechnology Co., Ltd. (Zhonghui Bio) reported significant growth in its first interim performance announcement post-IPO, driven by the commercialization of its core product, the quadrivalent influenza virus subunit vaccine, Hui Er Kang Xin® [1] Financial Performance - The company achieved a revenue of 71.12 million yuan in the first half of the year, representing a year-on-year increase of 918.91% [1] - Sales costs decreased by 18.3% year-on-year, while gross margin improved to 85.5% [1] - Losses narrowed by 22% compared to the previous year, indicating ongoing improvement in profitability [1] Product Development and Market Penetration - The quadrivalent influenza virus subunit vaccine, Hui Er Kang Xin®, is the first and only approved quadrivalent influenza subunit vaccine in China, with a 100% batch release qualification rate since its commercialization began in September 2023 [2] - The product's market coverage has expanded to 30 provinces, with over 1,100 county-level CDC collaborations, enhancing market penetration [2] - The vaccine's strategy for full population coverage has made significant progress, with an application for infants aged 6-35 months expected to be approved by Q3 2025 [2] Research and Development Pipeline - The lyophilized human rabies vaccine has entered the final clinical stage, showing good safety characteristics in Phase I trials [3] - The company has a diversified pipeline of 11 vaccines, with multiple key milestones expected between 2025 and 2026 [4] - The 23-valent pneumococcal polysaccharide vaccine has entered Phase III clinical sample preparation, while the recombinant shingles vaccine has commenced Phase II trials [4] Global Expansion Strategy - The company is building a global sales network, with plans to enter markets in Indonesia, Thailand, and Uruguay by 2025, and expand to Canada, Singapore, Mexico, and Hong Kong by 2026 [5] - The company has received registration certificates in Macau and is progressing smoothly with registration in the Philippines [5] - The R&D team is well-supported, with a significant portion of staff holding advanced degrees, ensuring robust pipeline advancement [5]

Core Viewpoint - The successful IPO of Zhonghui Biotech-B (02627) on August 11, 2025, marked a significant event in the Hong Kong stock market, with the stock price soaring by 157.98% on its first day, setting a record for the highest first-day gain of a new stock in 2025 [1] Company Overview - Zhonghui Biotech is a domestic innovative vaccine company with two core products: the quadrivalent influenza virus subunit vaccine (brand name: Huiru Kexin) and an in-development lyophilized human rabies vaccine [1][2] - The quadrivalent influenza vaccine is the first and only one approved in China for individuals aged 3 and above, showing significant improvements over traditional vaccines [2] Financial Performance - The public offering phase saw 191,000 participants with an oversubscription rate of 4007 times, freezing over HKD 210 billion, making it the "super subscription king" of the year in the biotech sector [1] - Sales revenue for Huiru Kexin is projected to reach HKD 260 million in 2024, a nearly 400% increase from HKD 52.2 million in 2023 [2] Product Pipeline - In addition to the two core products, Zhonghui Biotech has 11 other vaccines in development, including a trivalent influenza vaccine and a 23-valent pneumococcal polysaccharide vaccine, creating a diverse product pipeline [3] Market Trends - The Chinese innovative drug market is experiencing rapid growth, with the proportion of innovative drug business development (BD) transactions increasing from 10.8% in 2015 to 52.5% by August 2023 [3] - The global human vaccine market is expected to grow from USD 37.2 billion in 2019 to USD 49.8 billion in 2024, with a compound annual growth rate (CAGR) of 8.0% [5] Strategic Initiatives - Zhonghui Biotech's fundraising plan includes over 10% of funds allocated for strategic acquisitions, particularly in Southeast Asia, to enhance local production capabilities [4] - The company is also benefiting from favorable policies supporting innovative drugs, as indicated by recent meetings held by the National Medical Insurance Administration [5] Investment Appeal - The company is viewed as a defensive asset against global uncertainties, with its innovative vaccine technology positioned to thrive amid public health challenges [6] - The Chinese human vaccine market is projected to grow from RMB 53.5 billion in 2019 to RMB 96.1 billion in 2024, indicating substantial market potential [6]