证券代码：600196 股票简称：复星医药 编号：临 2025-160 上海复星医药（集团）股份有限公司 近日，上海复星医药（集团）股份有限公司（以下简称"本公司"）控股子公 司上海复宏汉霖生物技术股份有限公司及其控股子公司（以下合称"复宏汉霖"） 在研药品注射用 HLX43（即靶向 PD-L1 抗体偶联药物，以下简称"HLX43"）用于胸 腺上皮肿瘤（TETs）治疗获得美国 FDA（即美国食品药品监督管理局，下同）的孤 儿药资格认定（Orphan-drug Designation）。 二、HLX43 的基本信息及研究情况 HLX43 为复宏汉霖利用许可引进的新型 DNA 拓扑异构酶 I 抑制剂小分子毒素-肽 链连接子与其自主研发的靶向 PD-L1 的抗体进行偶联开发的靶向 PD-L1 的抗体偶联 药物（ADC），拟用于晚期/转移性实体瘤的治疗。截至本公告日期（即 2025 年 10 月 17 日，下同），HLX43 的主要研发进展情况如下： 1 适应症 进展 HLX43 单药 晚期/转移性实体瘤 （包括胸腺癌（TC）） 中国境内 1：处于 I 期临床试验阶段；其中， 胸腺癌（TC）队列为国际多中心试验 美国 ...

Core Viewpoint - Fosun Pharma's subsidiary, Fosun Kerry, is set to receive a total investment of 600 million yuan from the Shenzhen Biopharmaceutical Industry Fund as part of its Series A financing round, aimed at enhancing the company's growth and retaining key talent [1] Group 1: Financing and Investment - The Shenzhen Biopharmaceutical Industry Fund plans to invest a total of 600 million yuan in Fosun Kerry, contributing to a maximum of 524.44 million yuan in new registered capital [1] - A total of 14 participants, including current directors and core management of Fosun Kerry, will invest 3.525 million yuan through a co-investment platform, contributing to a total of 3.081 million yuan in new registered capital [1] Group 2: Equity Incentive Plan - To motivate and retain key personnel crucial for Fosun Kerry's business growth, the company will implement an equity incentive plan approved by both the board of directors and the shareholders' meeting [1] - The incentive plan will allow for the issuance of equity rights amounting to no more than 93.22 million yuan in registered capital, with the first batch not exceeding 76.18 million yuan [1] Group 3: Shareholding Structure - Following the completion of the financing, co-investment, and equity incentive plan, the group's shareholding in Fosun Kerry will decrease from approximately 97.78% to a maximum of 77.10%, while still maintaining control over the subsidiary [2]

证券代码：600196 股票简称：复星医药 编号：临 2025-159 上海复星医药（集团）股份有限公司 由于本公司若干董事、高级管理人员兼任深圳生物医药产业基金（系本公司之 联营企业）之投委会成员，根据上证所《上市规则》，深圳生物医药产业基金构成 本公司关联方、本次增资构成本公司的关联交易。 2、本次跟投 为充分调动复星凯瑞核心团队的积极性和创造性,于本次增资同时，包括复星凯 瑞现任董事及核心管理层在内的 14 名跟投参与方拟通过跟投平台共计出资 352.50 万元认缴复星凯瑞合计 308.1070 万元的新增注册资本。本次跟投的投前估值与本次 增资一致。 由于跟投参与方包括本公司董事陈玉卿先生、关晓晖女士及高级管理人员刘毅 先生、Xingli Wang 先生、Wenjie Zhang 先生、冯蓉丽女士、朱悦女士，根据上证 所《上市规则》，该等人士构成本公司关联方、其参与本次跟投构成本公司的关联 交易。 关于控股子公司增资扩股、实施跟投 及采纳并实施股权激励暨关联交易的公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重 ...

本报告依据中国资产评估准则编制 上海复健股权投资基金管理有限公司 拟投资涉及的复星凯瑞(上海)生物科技有限公司 股东全部权益价值项目 资产评估报告 中瑞评报字[2025]第 501086 号 (共一册,第一册) Werld Union A 中国资产评估协会 资产评估业务报告备案回执 | 报告编码: | 4743020020202501262 | | --- | --- | | 合同编号: | 2025-301038-1 | | 报告类型: | 法定评估业务资产评估报告 | | 报告文号: | 中瑞评报字[2025]第501086号 | | 报告名称: | 上海复健股权投资基金管理有限公司拟投资涉及的复星凯瑞(上 海)生物科技有限公司股东全部权益价值项目 | | 评估结论: | 2.246.412.451.69元 | | 评估报告日: | 2025年05月30日 | | 评估机构名称: | 中瑞世联资产评估集团有限公司 | | 签名人员: | 林海丰 (资产评估师) 正式会员 编号: 11140028 | | | 殷海斌 (资产评估师) 正式会员 编号: 11190036 | | | HEBER | (可扫描二 ...

Core Viewpoint - Fosun Pharma's subsidiary, Hanhui, has received orphan drug designation from the US FDA for its investigational drug HLX43, a PD-L1 targeted antibody-drug conjugate for the treatment of thymic epithelial tumors (TETs) [1] Group 1: Drug Development - HLX43 is a novel antibody-drug conjugate (ADC) developed by linking a small molecule toxin-peptide chain with a self-developed PD-L1 targeted antibody [1] - The drug is intended for the treatment of advanced/metastatic solid tumors [1] - As of the announcement date, HLX43 is in Phase I clinical trials in China, with the thymic carcinoma (TC) cohort being part of an international multicenter trial approved in the US and Japan [1] Group 2: Market Context - There are currently no approved PD-L1 targeted antibody-drug conjugates available in the global market [1]

Core Viewpoint - The 2025 Sustainable Global Leaders Conference held in Shanghai emphasizes global action, innovation, and sustainable growth, featuring around 500 attendees including Nobel Prize winners and leaders from Fortune 500 companies [1] Group 1: Innovation and Globalization - Fosun International's co-chairman, Wang Qunbin, highlighted the company's journey of globalization driven by innovation, aiming for a win-win in commercial and social value [3] - Fosun has developed the first approved anti-PD-1 monoclonal antibody, H drug, for the treatment of extensive-stage small cell lung cancer, which has been approved in nearly 40 countries, benefiting over 110,000 patients globally [4][5] - The company is transitioning from "following" to "leading" in the innovative drug sector, focusing on unmet clinical needs and global partnerships to advance healthcare [5] Group 2: Global Value Creation - Fosun has established a global presence in over 40 countries, building capabilities in research, registration, business development, and marketing, with its innovative biopharmaceutical products reaching nearly 600,000 patients [6] - The company has achieved significant growth in business development contracts, with cash inflow exceeding 1 billion yuan, a 280% increase year-on-year [6] - In the tourism sector, Fosun is enhancing customer experience through AI digital upgrades, expanding its services across 12 countries [6] Group 3: Corporate Social Responsibility - Fosun emphasizes the importance of ESG (Environmental, Social, Governance) responsibilities, contributing to global malaria control by supplying over 420 million doses of artemisinin-based injections [8][9] - The company has initiated a rural doctor project in China, benefiting 3 million rural families and over 16 million rural residents [9] - Fosun maintains a strong MSCI ESG rating of AA and is recognized in the top 1% of Chinese companies for sustainability efforts [9][10] Group 4: Future Vision - Wang Qunbin stated that the power of business for good is driving profound changes in the relationship between enterprises and society, and Fosun aims to continue climbing new heights in sustainable development [10]

Core Viewpoint - The company has announced a series of guarantees provided for its subsidiaries, totaling significant amounts, aimed at supporting their financing needs and ensuring operational stability [1][49]. Summary by Sections Guarantee Details - On October 14, 2025, the company signed a guarantee for its subsidiary, Fosun Pharma Industry, for a credit facility of RMB 700 million with China Merchants Bank, covering existing and new debts [1][11][13]. - A guarantee was also established for Fosun Health, covering a financing contract with a trust bank for up to RMB 150 million from October 14, 2025, to March 31, 2027 [2][16]. - On October 15, 2025, a guarantee was provided for Xuzhou Xingchen Hospital for a financing contract of up to RMB 157 million with SPD Bank [3][23]. - Additional guarantees were established for various subsidiaries, including Fosun Antigen, Hanjia Medical, and others, with amounts ranging from RMB 880,000 to RMB 10 million [5][31][39][45]. Cumulative Guarantee Situation - As of October 15, 2025, the total amount of guarantees provided by the group is approximately RMB 2,337.7 million, which represents 49.46% of the net assets attributable to shareholders as of December 31, 2024 [52]. Internal Decision-Making Process - The guarantees were approved by the company's board and the annual shareholders' meeting, ensuring compliance with internal governance procedures [8][50]. Necessity and Reasonableness of Guarantees - The guarantees are deemed necessary and reasonable, as they are intended to support the operational needs of the subsidiaries, with manageable risk levels [49]. Board Opinion - The board unanimously agreed on the necessity of the guarantees, considering them essential for the operational needs of the group and within the approved limits [50][51].

Group 1 - The core point of the article highlights that southbound funds have reduced their holdings in Fosun Pharma (02196.HK) by 704,000 shares on October 15, 2025, marking a trend of net reductions over recent trading days [1] - Over the past five trading days, southbound funds have reduced their holdings on four occasions, resulting in a total net reduction of 4.34 million shares [1] - In the last twenty trading days, there have been thirteen days of reductions, with a cumulative net decrease of 19.81 million shares [1] Group 2 - As of now, southbound funds hold 307 million shares of Fosun Pharma, which accounts for 55.57% of the company's total issued ordinary shares [1] - The trading data indicates a slight decrease in holdings, with a change of -0.23% on October 15, 2025, and a total holding of 307 million shares [2] - The company operates in five segments, including pharmaceuticals, medical devices, healthcare services, pharmaceutical distribution and retail, and other related businesses, focusing on treatments for oncology, immunology, and central nervous system disorders [2]

证券日报网讯 10月15日晚间，复星医药发布公告称，截至2025年10月15日，本集团无逾期担保事项。 （文章来源：证券日报） ...

证券代码：600196 证券简称：复星医药 公告编号：临 2025-158 上海复星医药（集团）股份有限公司 关于为控股子公司提供担保的进展公告 本公司董事会及全体董事保证本公告内容不存在任何虚假记载、误导性陈述 或者重大遗漏，并对其内容的真实性、准确性和完整性承担法律责任。 重要内容提示： 担保对象及基本情况 | | 名称 | 复星医药产业 | | --- | --- | --- | | | 本次担保金额 | 人民币 70,000 万元 | | 被担保方 1 | 截至 2025 年 10 月 15 日， 包括本次担保在内，本集 团实际为其提供的担保 | 折合人民币约 922,804 万元 | | | 余额 是否在前期预计额度内 | 是 □否 □不适用：________ | | | 本次担保是否有反担保 | 被担保方 1 系担保方（本公司）之全 资子公司，不涉及反担保安排 | | 被担保方 | 名称 | 复星健康 | | | 本次担保金额 | 人民币 19,800 万元 | | 2 | 截至 2025 年 10 月 15 日， 包括本次担保在内，本集 团实际为其提供的担保 余额 | 折合人民币约 204,6 ...