证券代码：300759 证券简称：康龙化成 公告编号：2025-036 康龙化成（北京）新药技术股份有限公司 | 1. 基本情况 | | | | | --- | --- | --- | --- | | 信息披露义务人（一） | Pharmaron Holdings Limited | | | | 住所 | CO Services Cayman Limited, P.O' Box 10008, Willow House, Cricket Square, Grand Cayman, KY1-1001, Cayman lslands | | | | 信息披露义务人（二） 楼小强 | | | | | 住所 | 北京市通州区马驹桥**** | | | | 信息披露义务人（三） | 宁波龙泰康投资管理有限公司 | | | | 住所 | 浙江省宁波杭州湾新区启源路 号 幢 室 39 1 341 | | | | 信息披露义务人（四） 郑北 | | | | | 住所 | 北京市通州区马驹桥**** | | | | 信息披露义务人（五） | 北海多泰创业投资有限公司 | | | | 住所 | 广西壮族自治区北海市银海区湖北路 2 ...

康龙化成（北京）新药技术股份有限公司 关于股东解除一致行动关系的公告 证券代码：300759 证券简称：康龙化成 公告编号：2025-033 本公司股东厦门龙泰鼎盛企业管理合伙企业（有限合伙）、厦门龙泰汇盛企业 管理合伙企业（有限合伙）、厦门龙泰汇信企业管理合伙企业（有限合伙）、厦门龙 泰众盛企业管理合伙企业（有限合伙）保证向本公司提供的信息内容真实、准确、 完整，没有虚假记载、误导性陈述或重大遗漏。 本公司及董事会全体成员保证公告内容与信息披露义务人提供的信息一致。 特别提示： 1、本次解除一致行动关系是因公司股东的普通合伙人暨执行事务合伙人发 生变更所致，不涉及股东持股数量变动； 2、本次一致行动关系解除不会导致公司实际控制人发生变化。 一、基本情况 郑北女士是公司实际控制人之一、董事、执行副总裁，在公司首次公开发行 股票并上市时，其作为员工持股平台的普通合伙人暨执行事务合伙人，实际控制 员工持股平台所持有公司股份的表决权，员工持股平台为郑北女士的一致行动人。 在一致行动关系存续期间，各方在公司重大事项的决策上始终保持一致意见，严 格履行相关承诺事项，不存在滥用自身控制地位的情形。 2025 年 6 月 ...

Core Insights - Ningbo Qianwan New Area is emerging as a hub for "unicorn" companies, with 11 enterprises listed in the 2025 Zhejiang Province unicorn company rankings, accounting for nearly one-third of Ningbo's total of 37 listed companies [1] - The total valuation of the 11 listed companies in Qianwan is approximately 25.25 billion yuan, driven by strong technological research and development capabilities [4] Unicorn Companies - The unicorn companies in Qianwan are primarily focused on "hard technology," with all 11 companies listed being categorized as such [1] - Kanglong Huacheng (Ningbo) Biopharmaceutical Co., Ltd. is the only unicorn in the life sciences sector, aiming to establish a world-class CGT (cell and gene therapy) drug R&D and production platform [2] Semiconductor Industry - Six of the listed companies in Qianwan are from the semiconductor industry, which is known for housing many unicorns and gazelles [2] - Qingchun Semiconductor, incubated by Fudan University Ningbo Research Institute, launched its first car-grade silicon carbide diode and MOSFET products within a year, filling domestic gaps [3] R&D Investment - Qianwan's total R&D expenditure surpassed 5 billion yuan for the first time in 2023, reaching 5.098 billion yuan, with an average growth rate of nearly 30% over the past three years [4] Digital Economy and Innovation - The Qianwan Digital Economy Industrial Park hosts over 40 companies engaged in R&D and production, with a total valuation exceeding 15 billion yuan [5] - The area has implemented forward-looking development policies for smart connected vehicles, digital economy, and biomedicine to attract potential projects [6] Financial Ecosystem - The financial ecosystem in Qianwan is continuously optimized to support the growth of unicorn companies, with nearly 100 capital matching events arranged annually [7] - Qianwan has established a leading capital market policy package, ensuring that companies receive necessary support at every growth stage [8] Investment and Collaboration - Qianwan has formed 31 sub-funds in collaboration with social capital, with a total scale approaching 25 billion yuan [9] - The region is focusing on AI and big data sectors, seeking professional fund collaboration teams to build an AI innovation industry cluster [9]

Core Viewpoint - The Hong Kong stock market is expected to open higher, with a positive pre-market performance in the innovative drug sector, driven by significant approvals for new drugs in China [1] Group 1: Market Performance - The Hong Kong innovative drug index constituents saw notable gains, with Innovent Biologics rising over 6%, and other companies like Zai Lab and WuXi AppTec increasing by over 2% [1] - The Hong Kong innovative drug ETF (159567) experienced a net inflow of over 165 million yuan in the past 20 trading days, indicating high market enthusiasm [1] - The price-to-earnings ratio of the Hong Kong innovative drug index decreased from 64 times on February 21 to 27 times on June 4, highlighting improved value for investors [1] Group 2: Regulatory Developments - On May 29, the National Medical Products Administration of China approved 11 innovative drugs, including 7 first-class innovative drugs, marking a historic moment for the sector [1] - Over 20 first-class innovative drugs have been approved from January to May, setting a record for the same period in the past five years [1] - The Chinese pharmaceutical industry is transitioning from "follow-up innovation" to "global leadership," focusing on clinical value in key areas like targeted cancer therapies and immunotherapy [1] Group 3: Investment Opportunities - The innovative drug ETF (159567) tracks the National Index of Hong Kong Innovative Drugs, with 90% of its weight in innovative drug companies, positioning it to benefit from trends like AI-enabled drug development and the expansion of domestic innovative drugs [1] - The innovative drug ETF (159992) encompasses leading companies in the innovative drug industry chain, benefiting from AI advancements and the introduction of new drug reimbursement policies [2] - The domestic innovative drug sector is expected to show strong growth and investment value in the first half of 2025, driven by ongoing international collaborations and the approval of new drugs [2]

Group 1 - The US government is pressuring countries to submit their best trade negotiation proposals by June 4, including tariffs and quotas for purchasing US agricultural products, or face punitive measures [1] - The Chinese government is tightening controls to prevent illegal outflow of strategic minerals, with various provinces enhancing regulatory measures [2] - The weakening of the US dollar is becoming a consensus among Wall Street banks, with the ICE dollar index down 8.9% year-to-date, leading to a rise in gold prices [3] Group 2 - Circle, a major stablecoin company, is set to go public on June 5, marking the first IPO in the stablecoin sector, which has positively impacted related stocks [4] - The Chinese government has issued new policies to improve the electricity service environment, which is expected to lower costs for small private enterprises and benefit power equipment companies [7] - Pharmaron, a leading CRO, is expanding its reach into overseas markets by investing in a healthcare fund, with a significant increase in revenue and new orders reported [8][10]

Group 1 - The core viewpoint of the news is the performance and holdings of the China Europe Medical Health Mixed Fund C, which has shown positive growth in its net value and returns over various time frames [1] - As of June 3, 2025, the latest net value of the fund is 1.6391 yuan, with a growth of 0.96%. The fund's return over the past month is 7.34%, ranking 224 out of 4690 in its category. Over the past three months, the return is 7.88%, ranking 461 out of 4620, and since the beginning of the year, the return is 8.66%, ranking 977 out of 4568 [1] - The top ten stock holdings of the fund account for a total of 55.30%, with significant positions in companies such as Heng Rui Pharmaceutical (10.60%), WuXi AppTec (9.95%), and Mindray Medical (5.21%) [1] Group 2 - The China Europe Medical Health Mixed Fund C was established on September 29, 2016, and as of March 31, 2025, it has a total scale of 15.566 billion yuan [1] - The fund manager, Ge Lan, has a background in biomedical engineering and has held various positions in research and fund management since joining China Europe Fund Management Company in October 2014 [2]

Group 1: Stock Movements and Market Reactions - JunDa Co., Ltd. (02865) fell by 12.69% due to weak fundamentals, expected shareholder sell-off, and cash flow concerns [1] - Rongchang Biopharmaceutical (09995) rose by 4.61% after ASCO announced positive data for RC108 combined with vorinostat, enhancing its commercialization prospects [1] - Datang Gold (08299) increased by 7.27% as it partnered with Wuxi to develop AI mining applications, benefiting from gold's safe-haven demand [1] - Kanglong Chemical (03759) gained 4.35% by investing in a biopharmaceutical fund, strengthening its investment ecosystem [1] - Automotive stocks surged following a significant increase in May's new energy vehicle sales, with Li Auto (2015) rising nearly 6% and Great Wall Motors (2333) up over 3% [1] - Gold stocks led the market as COMEX gold prices returned to $3,400, with Goldman Sachs predicting $4,200, driven by geopolitical tensions [1] Group 2: Company-Specific Developments - Changfei Optical Fiber (06869) rose by 8.34% as its Wuhan base began mass production of 6-inch silicon carbide wafers, achieving a 97% yield rate [2] - China Shipbuilding Defense (00317) increased by 7.58% after securing the highest global new orders from January to April, with Q1 net profit up 1,099% [2] - Hengrui Medicine (00013) rose by 5.09% as SACHI III phase data met expectations, opening up market space for MET amplification lung cancer treatment [2] - Lepu Medical Technology (02157) gained 5.76% following positive ASCO data for its ADC drug MRG003, boosting approval expectations for nasopharyngeal carcinoma [2] - Aidi Kang Holdings (09860) increased by 5.2% after acquiring Suzhou Yuande Youqin to enhance blood disease diagnostics [2] - NetDragon (00777) rose by 5.82% due to its collaboration with Thailand on an AI education platform, attracting investor interest [2] Group 3: Notable Market Trends - China Everbright Holdings (00165) surged over 21% following the enactment of Hong Kong's stablecoin regulations, with Circle's IPO expectations boosting related equity valuations [3] - iFlytek Medical (02506) rose by 6.62% as its medical AI model demonstrated superior accuracy, supported by favorable policies [3] - MicroPort NeuroTech (02172) increased by 9.59% as it initiated clinical research on brain-machine interfaces, benefiting from policy incentives [3] - Longpan Technology (02465) rose by 14.9% after its subsidiary signed a $7.1 billion contract with Yiwei Lithium Energy for lithium iron phosphate [4] - Hansoh Pharmaceutical (03692) gained 3.85% after reaching a global licensing agreement with Regeneron, receiving an $80 million upfront payment [4] Group 4: U.S. Market Highlights - Steel and aluminum stocks surged over 10%-28% as Trump proposed increasing steel tariffs to 50%, benefiting domestic companies [5] - Blueprint Medicines (BPMC.US) rose by 26% following Sanofi's $9.1 billion acquisition, enhancing its rare disease pipeline [5] - BioNTech (BNTX.US) increased by 18% due to a collaboration with Bristol-Myers Squibb, securing a $1.5 billion upfront payment [5] - Applied Digital (APLD.US) surged by 48.46% after signing a $7 billion AI data center lease, validating its business model [5] - Tempus AI (TEM.US) rose by 15% as it launched an AI medical innovation plan, attracting investor interest [7]

华创证券表示，创新药重磅BD不断，未来潜力管线丰富，掘金海外市场。展望2025年，我们认为医药 板块已经具备多方面的积极发展因素，基本完成了新旧增长动能转换（创新+出海能力提升）。具体配 置方面，建议关注创新药械（业绩/创新拐点的Pharma以及临床阶段的高价值资产）、出海（CXO及科 研上游、供应链、医疗器械及高端生物药和制剂）、国产创新（医疗设备和高值耗材）、老龄化及院外 消费（家用器械、中药等）、高壁垒行业（血制品、麻药）、AI医疗，同时建议积极关注估值较低有 望修复的优质标的。 国金证券发布研报称，国家药监局批准11款全新创新药的上市申请，另外还有2款创新药拟纳入优先审 评，新品种密集获批有望赶上今年医保谈判放量，为相关企业业绩增长提供助力。同时政策端对创新药 的支持持续，叠加海外授权重磅交易不断落地，创新药景气度有望持续。当前环境下，建议重点关注仿 创药板块重估机会。同时，后期可能的国家医保谈判和集采进程也是投资把握的重要节点。 6月3日，A股、港股开盘后震荡上涨，医药板块走高，创新药概念再度走强。相关ETF方面，创新药 ETF天弘（517380）截至发稿涨0.80%，盘中交投活跃。成分股超八成飘红 ...

Group 1 - The majority of Hong Kong pharmaceutical stocks are experiencing declines, with Hansoh Pharmaceutical falling over 4% [1] - Hansoh Pharmaceutical (03692.HK) decreased by 4.45%, while other companies like Aimeijia Vaccine (06660.HK) and CSPC Pharmaceutical Group (01093.HK) also saw significant drops of 3.98% and 2.72% respectively [1] - Kanglong Chemical (03759.HK) reported a decline of 1.83%, indicating a broader trend of weakness in the sector [1]

教育股也普遍上扬。其中，中教控股（00839.HK）涨8.7%，新东方-S（09901.HK）涨4.32%,思考乐教 育（01769.HK）涨2.56%,卓越教育集团（03978.HK）涨2.74%。 节假日概念股、体育用品、奢侈品股、香港零售股等消费股走高。美团-W（03690.HK）涨6.62%，消 息面，美团闪购618发布了酒品类首日战报，自5月28日启动以来的24小时内，酒类整体成交额相比增长 超18倍。同程旅行（00780.HK）涨4.34%，携程集团-S（09961.HK）涨3.51%，安踏体育（02020.HK） 涨4.18%，361度（01361.HK）涨3.49%。 稳定币概念板块午后爆发，其中，连连数字（02598.HK）飙升44.86%，众安在线（06060.HK）大涨 31.56%。消息面，美国副总统万斯5月28日表示，本届政府不认为稳定币会威胁美元的完整性。恰恰相 反，将其视为美国经济实力的倍增器。此外，近期香港立法会三读通过的《稳定币条例草案》。今年年 底前，合规的香港稳定币有望正式落地。 短视频概念、明星科网股等均表现活跃。快手-W（01024.HK）涨4.94%，京东集团-SW ...