Core Viewpoints - Zai Ding Pharma reported a 9% year-on-year revenue growth for Q2 2025, with total revenue reaching $110 million, despite a slowdown due to declining sales of the PARP inhibitor Niraparib, attributed to intensified competition in the same category [1] - The company expects rapid revenue growth in the next two to three years as multiple new products and indications are anticipated to be approved, aiming for operational profitability by Q4 2025 [1] - Key catalysts in the second half of the year include detailed data disclosure from the Phase III clinical trial of Bemarituzumab (FORTITUDE-101) and data readout from the Phase III trial of KarXT (ADEPT-2) [1] Financial Performance - In Q2 2025, Zai Ding Pharma's adjusted operating loss narrowed by 37% to $34.2 million, while net loss decreased by 28% to $54.9 million [1] - Revenue from Niraparib was $41 million, a 9% decline year-on-year due to competitive pressures, while Aigamod revenue grew by 14% year-on-year to $26.5 million, benefiting from extended treatment cycles and increased market penetration [1] - Omaveloxolone generated $14.3 million in revenue, reflecting a 16% year-on-year increase due to expanded market coverage [1] Product Pipeline and Innovations - ZL-1310 has received accelerated development status in small cell lung cancer, and Bemarituzumab has met primary endpoints in its Phase III study for FGFR2b overexpressing gastric cancer, with plans for a market application submission in China [2] - Aigamod has been upgraded in the Chinese guidelines for myasthenia gravis, highlighting its clinical value for early and long-term treatment [2] - ZL-1503 shows promising treatment prospects for atopic dermatitis, supported by its long half-life characteristics [2] Clinical Data and Efficacy - The global Phase II FIGHT study for Bemarituzumab demonstrated a median overall survival of 19.2 months in the chemotherapy combination group, with significant survival benefits in the FGFR2b overexpressing subgroup [3] - In the East Asian subgroup, median overall survival was further optimized to 30.1 months, underscoring the importance of biomarker selection for efficacy [3]

Core Viewpoint - The company announced a grant of restricted stock units to three recipients under the 2024 equity incentive plan, totaling 3,300 American Depositary Shares [1] Group 1 - The announcement was made on August 13, 2023, regarding the equity incentive plan [1] - The restricted stock units will be granted on August 11, 2025, Eastern Time [1] - The total number of restricted stock units involved is 3,300 [1]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完整性亦 不發表任何聲明，並明確表示，概不會對因本公告全部或任何部分內容而產生或因倚賴該等內容而引致的 任何損失承擔任何責任。 Zai Lab Limited 再鼎醫藥有限公司* （於開曼群島註冊成立的有限公司） （股份代號：9688） 授出受限制股份單位 本公告乃根據上市規則第17.06A、17.06B以及17.06C條作出。董事會謹此宣佈，於2025 年8月11日（美國東部時間），本公司根據2024年股權激勵計劃向3名承授人涉及合共 3,300股美國存託股份的受限制股份單位。 授出2024年股權激勵計劃項下的受限制股份單位 本公司根據2024年股權激勵計劃條款向3名承授人授出3,300份受限制股份單位（以美國 存託股份計）。 受限制股份單位授出詳情如下： | 授出日期： | 2025年8月11日（美國東部時間） | | --- | --- | | 承授人數目： | 3 | | 承授人類型： | 本集團僱員參與者 | | 所授出受限制股份單位數目 | 3,300 | | （以美國存託股份計）： | | | 所授出受限制股份單 ...

Core Insights - Zai Ding Pharma (ZLAB) opened with a 2.3% increase on August 13, reaching $35.1 per share, with a total market capitalization of $3.923 billion [1][2] Financial Performance - As of June 30, 2025, Zai Ding Pharma reported total revenue of $216 million, reflecting a year-on-year growth of 15.35% [1] - The company's net profit attributable to shareholders was -$89.165 million, showing a year-on-year increase of 33.33% [1][2] - Basic earnings per share for the fiscal year 2025 were reported at -$0.08 [2] Company Overview - Zai Ding Pharma is a patient-centered, innovative global biopharmaceutical company that is in the commercialization stage, focusing on providing optimal and first-in-class drugs for oncology, autoimmune diseases, infectious diseases, and central nervous system disorders [2] - The company's mission is to become a leading global biopharmaceutical company, offering transformative innovative drugs to patients in China and worldwide [2] - Zai Ding Pharma aims to establish itself as a global leader in biopharmaceuticals, with a foundation in China to provide innovative therapies for patients globally [2]

香港交易及結算所有限公司及香港聯合交易所有限公司對本公告的內容概不負責，對其準確性或完整性亦 不發表任何聲明，並明確表示，概不會對因本公告全部或任何部分內容而產生或因倚賴該等內容而引致的 任何損失承擔任何責任。 Zai Lab Limited 再鼎醫藥有限公司 * （於開曼群島註冊成立的有限公司） （股份代號：9688） 本公司根據香港上市規則將刊發的中期業績與本公司先前公佈並向證交會提交的業績相同，惟香 港上市規則規定須披露的若干附加資料以及本公司業績從美國公認會計準則至國際財務報告準則 的對賬結果除外。 承董事會命 再鼎醫藥有限公司 董事、董事長兼首席執行官 杜瑩 香港，2025 年 8 月 13 日 於本公告日期，本公司董事會包括董事杜瑩博士；以及獨立董事 John Diekman 博士、 Richard Gaynor 博士、 梁頴宇女士、 William Lis 先生、 Scott W. Morrison 先生、 Leon O. Moulder, Jr. 先生、 Michel Vounatsos 先生及 Peter Wirth 先生。 * 僅供識別 審核委員會行動通告 再鼎醫藥有限公司（「本公司」）董 ...

Group 1 - The core viewpoint of the article highlights that Zai Lab (ZLAB.US) saw a pre-market increase of 3.44%, reaching $35.49, following a report from CICC regarding the National Healthcare Security Administration's announcement on the preliminary review of drug directories [1] - A total of 534 drugs passed the preliminary review, indicating the expected launch of a dual-directory mechanism that will clarify the roles of basic medical insurance and commercial insurance for innovative drugs [1] - The report suggests that the combination of basic medical insurance support and the expansion of commercial insurance is likely to encourage commercial insurance companies to invest in innovative drug development through various means, providing stable long-term investment for R&D [1] Group 2 - The focus on high-value innovative drugs that are not covered by basic medical insurance but have significant clinical value is emphasized, which may lead to increased clinical penetration and enhanced market value for these drugs [1] - CICC recommends paying attention to stocks like Zai Lab, which may benefit from the new insurance policies and the potential for increased investment in innovative drug development [1]

Group 1 - The Hong Kong stock market showed strong performance on August 13, with the Hang Seng Index rising by 1.88% and the Hang Seng Tech Index increasing by 2.35%, particularly driven by the healthcare sector [1] - The Hong Kong Innovative Drug 50 ETF (513780) closed up by 3.38% with a turnover rate exceeding 18% and a transaction volume of over 400 million yuan, indicating strong investor interest [1] - Notably, the Hong Kong Innovative Drug 50 ETF (513780) experienced a net inflow of 1.07 billion yuan over the past 15 trading days, and it has gained over 92% year-to-date as of August 12 [1] Group 2 - The National Healthcare Security Administration announced the preliminary review results for the 2025 medical insurance directory and commercial insurance innovative drug directory, with 534 drugs passing the basic medical insurance directory review and 121 drugs passing the commercial insurance innovative drug directory review [2] - High-priced innovative drugs, including CAR-T therapies, are seeking inclusion in the commercial insurance innovative drug directory, indicating a push for diversified payment methods for innovative drugs [2] - Analysts suggest that the rise of innovative drugs is sustainable, recommending attention to companies with rich pipeline layouts, high-potential single innovative drugs, and leading technology platforms in the sector [2]

Summary of Key Points Core Viewpoint - The report highlights the top short-selling stocks in Hong Kong, indicating significant short-selling activity in companies like New World Development, Hong Kong Exchanges, and BYD, with notable short-selling ratios and amounts [1][2]. Short-Selling Ratios - New World Development (80016) has the highest short-selling ratio at 100.00% - Hong Kong Exchanges (80388) follows with a short-selling ratio of 94.27% - BYD (81211) has a short-selling ratio of 94.13% [1][2]. Short-Selling Amounts - Alibaba (09988) leads in short-selling amount with HKD 1.546 billion - Tencent (00700) has a short-selling amount of HKD 1.265 billion - Xiaomi (01810) follows with HKD 1.188 billion [1][2]. Deviation Values - Hong Kong Exchanges (80388) has the highest deviation value at 54.37% - New World Development (80016) has a deviation value of 41.90% - Alibaba (89988) shows a deviation value of 39.84% [1][2].

Key Points - The top three stocks with net inflows from southbound funds are Yingfu Fund (02800) with 1.184 billion, Alibaba-W (09988) with 730 million, and Hang Seng China Enterprises (02828) with 556 million [1] - The top three stocks with net outflows are WuXi Biologics (02269) with -539 million, Hua Hong Semiconductor (01347) with -509 million, and SMIC (00981) with -432 million [1] - In terms of net inflow ratio, Shanghai Industrial Holdings (00363) leads with 63.56%, followed by Bank of China Aviation Leasing (02588) with 60.26%, and Sunshine Insurance (06963) with 55.37% [1] - The top three stocks with the highest net outflow ratios are GX China (03040) at -100.00%, Southern Hang Seng Index ETF (03037) at -65.52%, and Sichuan Chengyu Expressway (00107) at -49.23% [1] Top 10 Net Inflows - Yingfu Fund (02800) had a net inflow of 1.184 billion, representing a 16.79% increase, closing at 25.380 [2] - Alibaba-W (09988) saw a net inflow of 730 million, with a 10.34% increase, closing at 116.300 [2] - Hang Seng China Enterprises (02828) had a net inflow of 556 million, with an 8.70% increase, closing at 91.160 [2] - Xiaomi Group-W (01810) had a net inflow of 473 million, with a 6.69% increase, closing at 51.250 [2] - Zai Ding Pharmaceutical (09688) had a net inflow of 429 million, with a 26.73% increase, closing at 27.200 [2] Top 10 Net Outflows - WuXi Biologics (02269) experienced a net outflow of -539 million, with a -33.02% decrease, closing at 29.360 [2] - Hua Hong Semiconductor (01347) had a net outflow of -509 million, with a -21.78% decrease, closing at 44.000 [2] - SMIC (00981) saw a net outflow of -432 million, with a -3.98% decrease, closing at 48.660 [2] - Kuaishou-W (01024) had a net outflow of -292 million, with a -14.76% decrease, closing at 79.150 [2] - Juzi Biotechnology (02367) experienced a net outflow of -220 million, with a -24.75% decrease, closing at 59.000 [2] Net Inflow Ratios - Shanghai Industrial Holdings (00363) had a net inflow ratio of 63.56%, with a net inflow of 11.36 million, closing at 14.870 [3] - Bank of China Aviation Leasing (02588) had a net inflow ratio of 60.26%, with a net inflow of 3.56 million, closing at 73.500 [3] - Sunshine Insurance (06963) had a net inflow ratio of 55.37%, with a net inflow of 2.48 million, closing at 3.790 [3] - Poly Property (06049) had a net inflow ratio of 52.60%, with a net inflow of 1.14 million, closing at 34.880 [3] Net Outflow Ratios - GX China (03040) had a net outflow ratio of -100.00%, with a net outflow of -7100.00, closing at 35.460 [3] - Southern Hang Seng Index ETF (03037) had a net outflow ratio of -65.52%, with a net outflow of -724,900, closing at 25.400 [3] - Sichuan Chengyu Expressway (00107) had a net outflow ratio of -49.23%, with a net outflow of -380,740, closing at 4.920 [3]

智通财经APP讯，再鼎医药(09688)发布公告，于2025年8月12日，该公司根据股权激励计划发行684.43 万股。 （原标题：再鼎医药(09688)根据股权激励计划发行684.43万股） ...